KR20220047600A - 진단 시스템 - Google Patents

진단 시스템 Download PDF

Info

Publication number
KR20220047600A
KR20220047600A KR1020227008221A KR20227008221A KR20220047600A KR 20220047600 A KR20220047600 A KR 20220047600A KR 1020227008221 A KR1020227008221 A KR 1020227008221A KR 20227008221 A KR20227008221 A KR 20227008221A KR 20220047600 A KR20220047600 A KR 20220047600A
Authority
KR
South Korea
Prior art keywords
sample
cartridge
inspect
chamber
module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020227008221A
Other languages
English (en)
Korean (ko)
Inventor
사예드 안데시만드
토마스 에이치. 3세 컬리
존 딕슨
데이비드 글레이드
헤디아 마마르
마이클 존 맥아담스
잠-시 제시 응
데이비드 알렉산더 롤프
Original Assignee
탈리스 바이오메디컬 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 탈리스 바이오메디컬 코포레이션 filed Critical 탈리스 바이오메디컬 코포레이션
Publication of KR20220047600A publication Critical patent/KR20220047600A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221—Valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150961—Means for the detection of the presence or absence of a module, a component or an abnormal condition; detection of leaks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/021—Identification, e.g. bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/047—Additional chamber, reservoir
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Psychology (AREA)
  • Manufacturing & Machinery (AREA)
  • Virology (AREA)
  • General Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020227008221A 2019-08-15 2020-08-17 진단 시스템 Withdrawn KR20220047600A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962887469P 2019-08-15 2019-08-15
US62/887,469 2019-08-15
US16/655,007 2019-10-16
US16/655,028 2019-10-16
US16/655,007 US10820847B1 (en) 2019-08-15 2019-10-16 Diagnostic system
US16/655,028 US11008627B2 (en) 2019-08-15 2019-10-16 Diagnostic system
PCT/US2020/046721 WO2021030812A2 (en) 2019-08-15 2020-08-17 Diagnostic system

Publications (1)

Publication Number Publication Date
KR20220047600A true KR20220047600A (ko) 2022-04-18

Family

ID=73019724

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227008221A Withdrawn KR20220047600A (ko) 2019-08-15 2020-08-17 진단 시스템

Country Status (15)

Country Link
US (5) US11008627B2 (https=)
EP (1) EP4013893A4 (https=)
JP (1) JP2022544530A (https=)
KR (1) KR20220047600A (https=)
CN (1) CN114555828A (https=)
AU (1) AU2020327367A1 (https=)
BR (1) BR112022002789A2 (https=)
CA (1) CA3146765A1 (https=)
CL (1) CL2022000350A1 (https=)
CO (1) CO2022002783A2 (https=)
IL (1) IL290104A (https=)
JO (1) JOP20220026A1 (https=)
MX (1) MX2022001493A (https=)
PH (1) PH12022550372A1 (https=)
WO (1) WO2021030812A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025034038A1 (ko) * 2023-08-09 2025-02-13 경희대학교 산학협력단 유전자 분석용 카트리지 및 이를 포함하는 유전자 분석장치

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3134430A1 (en) * 2019-03-22 2020-10-01 Siemens Healthcare Diagnostics Inc. Biological sample analyzer with forced air convection plenum
AU2020248704B2 (en) 2019-03-22 2023-02-16 Siemens Healthcare Diagnostics Inc. Biological sample analyzer with accelerated thermal warming
US11008627B2 (en) 2019-08-15 2021-05-18 Talis Biomedical Corporation Diagnostic system
KR20220119071A (ko) * 2019-12-18 2022-08-26 라이프 테크놀로지스 코포레이션 자동화된 핵산 및 단백질 분리를 위한 시스템, 방법 및 장치
US20210252508A1 (en) * 2020-02-15 2021-08-19 Heska Corporation Sample cartridges
US20210290123A1 (en) * 2020-03-20 2021-09-23 Sea Run Holdings, Inc. Device and Method of Obtaining Aseptic Blood from Fish
MX2022014282A (es) * 2020-05-13 2023-02-22 Quidel Corp Sistema y cartucho para prueba de muestras.
JP2023529088A (ja) 2020-05-29 2023-07-07 クイデル コーポレーション 疾病診断用の試料検定の遠隔評価のためのシステム及び方法
WO2021243179A1 (en) * 2020-05-29 2021-12-02 Quidel Corporation System and methods for remote assessment of a sample assay for disease diagnostics
DE102020115728A1 (de) * 2020-06-15 2021-12-16 Agilent Technologies, Inc. Mikrofluidisches Bauteil mit Metallschichtstapel und damit gebondetem Fluidleitungselement aus anderem Material
GB202013087D0 (en) * 2020-08-21 2020-10-07 Vidya Holdings Ltd A combined sample collection and filtration device
US11384403B2 (en) * 2020-11-10 2022-07-12 Dnanudge Limited Use of pooled samples to optimise the efficiency and utility of a rapid, lab-free point-of-care test
WO2022101161A2 (en) * 2020-11-10 2022-05-19 Dnanudge Limited Point-of-care test for a group of individuals
US20220228226A1 (en) * 2021-01-15 2022-07-21 Purdue Research Foundation Loop-mediated isothermal amplification (lamp) analysis for pathogenic targets
US20220280573A1 (en) * 2021-03-03 2022-09-08 Axogen Corporation Human umbilical cord-derived compositions and uses thereof for treating neuropathy
GB2605956B (en) * 2021-04-14 2026-03-11 Univ Of South Eastern Norway Systems, apparatus and methods for extracting and analysing cellular material
US20240226887A1 (en) * 2021-04-27 2024-07-11 Northwestern University Analyte detection cartridge and methods of use thereof
US12352570B2 (en) * 2021-04-29 2025-07-08 Beijing Boe Technology Development Co., Ltd. Cabin entry-and-exit structure of analysis device, analysis device and analysis system
WO2022251508A1 (en) * 2021-05-28 2022-12-01 Proof Diagnostics Reaction cartridge
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
US20240342702A1 (en) * 2021-07-28 2024-10-17 Bioeclosion, S.L. Device for assay system, system and method
CN115877025B (zh) * 2021-08-27 2026-03-24 广州万孚生物技术股份有限公司 体外分析诊断检测装置及卡盒阀门控制组件
US20240390886A1 (en) * 2021-09-24 2024-11-28 Cubit Diagnostics, Inc. Timed system for rapid assay
US20230182133A1 (en) * 2021-12-01 2023-06-15 Graphene-Dx. Inc. Systems and methods for processing and testing biological samples
US12415183B1 (en) * 2021-12-09 2025-09-16 Amazon Technologies, Inc. Microfluidic systems and methods
CN114836308B (zh) * 2022-03-13 2023-03-21 首玺(广州)医疗科技有限责任公司 一种核酸检测试剂盒及其制备工艺
US12100143B2 (en) * 2022-05-13 2024-09-24 City University Of Hong Kong Label-free liquid biopsy-based disease model, analytical platform and method for predicting disease prognosis
US20240139726A1 (en) * 2022-10-28 2024-05-02 Seegene, Inc. Cartridge for detecting target analyte
KR102921590B1 (ko) * 2022-10-28 2026-02-03 주식회사 씨젠 타깃 분석물 검출 카트리지
US20240139740A1 (en) * 2022-10-28 2024-05-02 Seegene, Inc. Cartridge for detecting target analyte
KR102758657B1 (ko) * 2022-11-17 2025-01-22 엔트온(주) 유체분석기
TWI889052B (zh) * 2023-08-16 2025-07-01 新加坡商克雷多生醫股份有限公司 卡匣及其定量方法
CN117264750B (zh) * 2023-11-23 2024-01-30 中国科学院空天信息创新研究院 检测卡盒及其使用方法
WO2025138301A1 (zh) * 2023-12-30 2025-07-03 深圳市理邦精密仪器股份有限公司 医疗检测设备和用于医疗检测设备的试剂盒
WO2026024803A1 (en) * 2024-07-26 2026-01-29 Siemens Healthcare Diagnostics Inc. Test consumables that maintain sample integrity for use in diagnostic sample analyzers
WO2026024810A1 (en) * 2024-07-26 2026-01-29 Siemens Healthcare Diagnostics Inc. Methods and apparatus for facilitating sample movement and placement within test cards
WO2026043913A1 (en) * 2024-08-20 2026-02-26 Gen-Probe Incorporated On-board lysis, internal control, and volumetric expansion in a fluidic cartridge

Family Cites Families (366)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2350534A (en) 1942-10-05 1944-06-06 Rosinger Arthur Magnetic stirrer
US2428410A (en) 1943-07-30 1947-10-07 Lee G Daniels Rotary type multiport valve
US2451678A (en) 1945-04-04 1948-10-19 Automatic Pump & Softener Corp Multiple port valve structure
US2598362A (en) 1945-11-28 1952-05-27 Lee G Daniels Multiport rotary plate valve
US2857929A (en) 1954-03-22 1958-10-28 Aquamatic Inc Multiport valve
US2982132A (en) 1956-07-24 1961-05-02 Mount Sinai Hospital Res Found Calorimetric method and apparatus for continuous recording of heat exchange between bodies
US2990256A (en) 1957-05-01 1961-06-27 Curtiss Wright Corp Crystal growing apparatus
US3211433A (en) 1963-12-02 1965-10-12 Joseph E Chrostowski Magnetic stirring apparatus
US3454178A (en) 1966-01-10 1969-07-08 Charles E Bender Sterile cap for a freeze-drying container and method of freeze-drying materials under sterile conditions
US3689224A (en) 1966-04-13 1972-09-05 Westinghouse Electric Corp Chemical contaminant detection sampler
US3503410A (en) 1967-03-16 1970-03-31 George B Richards Fluid amplifier
US3495253A (en) 1967-06-26 1970-02-10 George B Richards Planar fluid amplifier
US3570819A (en) 1968-01-08 1971-03-16 Arther Rosinger Magnetic stirrers
US3504799A (en) 1968-04-02 1970-04-07 Beckman Instruments Inc Sample injector
SE327340B (https=) 1968-08-26 1970-08-17 Atlas Copco Ab
US3776276A (en) 1971-03-15 1973-12-04 M Stiltner Valve seal
NL179870C (nl) 1974-08-16 1986-12-01 Sarstedt Kunststoff Vat voor het afnemen van bloed met een capillair mondstuk.
US4119407A (en) 1976-03-08 1978-10-10 Bio-Dynamics, Inc. Cuvette with reagent release means
US4070249A (en) 1976-06-08 1978-01-24 American Home Products Corporation Apparatus for compensating for pressure within a biological test device
US6779557B2 (en) 2002-08-22 2004-08-24 Mego Afek Industrial Measuring Instruments Rotary disc valve
US4618476A (en) 1984-02-10 1986-10-21 Eastman Kodak Company Capillary transport device having speed and meniscus control means
US4608231A (en) 1984-12-12 1986-08-26 Becton, Dickinson And Company Self-contained reagent package device for an assay
US5279294A (en) 1985-04-08 1994-01-18 Cascade Medical, Inc. Medical diagnostic system
US4964539A (en) 1989-04-06 1990-10-23 Seaquist Closures Multiple chamber dispensing container and closure system
US5195877A (en) 1990-10-05 1993-03-23 Kletschka Harold D Fluid pump with magnetically levitated impeller
EP0501796A3 (en) 1991-03-01 1993-10-06 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
US5256571A (en) 1991-05-01 1993-10-26 Cytyc Corporation Cell preservative solution
US5837546A (en) 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
US6403367B1 (en) 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
JPH10503993A (ja) 1994-08-19 1998-04-14 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 凍結乾燥用のベント式バイアルと凍結乾燥された生産品の汚染を最少限にする方法
GB9501229D0 (en) 1995-01-21 1995-03-15 Robinson Alan K Improvements relating to magnetic coupling systems
EP0830510A1 (en) 1995-06-07 1998-03-25 Concis, L.L.C. Microfabricated, tube located gear pump system
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5662866A (en) 1995-09-25 1997-09-02 Steris Corporation Two compartment cup for powdered sterilant reagent components
US5639074A (en) 1996-03-05 1997-06-17 Smalley Steel Ring Co. Interlaced wave spring
FR2749663B1 (fr) 1996-06-07 1998-07-31 Bio Merieux Carte d'analyse a usage unique comprenant un conduit d'ecoul ement de liquides
US6074827A (en) 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
GB9620934D0 (en) 1996-10-08 1996-11-27 Molecular Drives Limited Multi-well containers
US6027694A (en) 1996-10-17 2000-02-22 Texperts, Inc. Spillproof microplate assembly
AU736154B2 (en) 1997-10-27 2001-07-26 Idexx Laboratories, Inc. Device and methods for determination of analyte in a solution
US6043097A (en) 1997-12-05 2000-03-28 Bayer Corporation Reagent package
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
FR2784522B1 (fr) 1998-10-07 2001-01-05 Cogema Dispositif d'agitation de liquide a accouplement magnetique
US6637463B1 (en) 1998-10-13 2003-10-28 Biomicro Systems, Inc. Multi-channel microfluidic system design with balanced fluid flow distribution
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US6416215B1 (en) 1999-12-14 2002-07-09 University Of Kentucky Research Foundation Pumping or mixing system using a levitating magnetic element
WO2000049382A2 (en) 1999-02-16 2000-08-24 The Perkin-Elmer Corporation Bead dispensing system
JP4078073B2 (ja) * 1999-05-28 2008-04-23 シーフィード 流体試料分析装置および方法
US6357907B1 (en) 1999-06-15 2002-03-19 V & P Scientific, Inc. Magnetic levitation stirring devices and machines for mixing in vessels
US7195670B2 (en) 2000-06-27 2007-03-27 California Institute Of Technology High throughput screening of crystallization of materials
US6250618B1 (en) 1999-09-10 2001-06-26 Smalley Steel Ring Company Curved wave shim
GB9922971D0 (en) 1999-09-29 1999-12-01 Secr Defence Reaction system
US6431202B1 (en) 1999-12-01 2002-08-13 Calgon Carbon Corporation Fluid-directing multiport rotary valve
US20010039369A1 (en) 1999-12-14 2001-11-08 Terentiev Alexandre N. Blood pump system
US6758593B1 (en) 2000-10-09 2004-07-06 Levtech, Inc. Pumping or mixing system using a levitating magnetic element, related system components, and related methods
US6254071B1 (en) 1999-12-20 2001-07-03 Smalley Steel Ring Company Single-turn, round wire wave spring
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
DE10006214A1 (de) 2000-02-11 2001-08-16 Roche Diagnostics Gmbh System zur einfachen Nukleinsäureanalytik
US6357476B1 (en) 2000-05-12 2002-03-19 Project Service S.R.L. Hot and cold water mixing/distributing valve with three or more outlets
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
EP1314024A4 (en) 2000-08-02 2007-04-11 Caliper Life Sciences Inc HIGH PERFORMANCE-BASED SEPARATION-BASED ANALYSIS SYSTEMS
US6615856B2 (en) 2000-08-04 2003-09-09 Biomicro Systems, Inc. Remote valving for microfluidic flow control
US6374684B1 (en) 2000-08-25 2002-04-23 Cepheid Fluid control and processing system
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
US7086778B2 (en) 2000-10-09 2006-08-08 Levtech, Inc. System using a levitating, rotating pumping or mixing element and related methods
US6663276B2 (en) 2000-10-10 2003-12-16 Smithkline Beecham Corporation Stirring element and associated metering gun
US6382827B1 (en) 2000-11-01 2002-05-07 Dade Behring Inc. Method and apparatus for mixing liquid solutions using a rotating magnet to generate a stirring vortex action
US6453928B1 (en) 2001-01-08 2002-09-24 Nanolab Ltd. Apparatus, and method for propelling fluids
US20050047976A1 (en) 2001-01-25 2005-03-03 Klaus Gubernator Method and apparatus for solid or solution phase reaction under ambient or inert conditions
US6805841B2 (en) 2001-05-09 2004-10-19 The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Liquid pumping system
US20040208751A1 (en) 2001-05-22 2004-10-21 Lazar Juliana M Microchip integrated multi-channel electroosmotic pumping system
US7179423B2 (en) 2001-06-20 2007-02-20 Cytonome, Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
US6702256B2 (en) 2001-07-17 2004-03-09 Agilent Technologies, Inc. Flow-switching microdevice
WO2003013703A1 (en) 2001-08-03 2003-02-20 Aclara Biosciences, Inc. Straightflow system
EP2311934B1 (en) 2001-09-06 2013-06-05 Rapid Micro Biosystems, Inc. Rapid detection of replicating cells
JP4103363B2 (ja) 2001-09-18 2008-06-18 三菱電機株式会社 流量制御装置、冷凍サイクル装置および空気調和装置
US7318448B2 (en) 2001-11-30 2008-01-15 H-Tech, Inc. Swimming pool cleaning apparatus and parts therefor
US20030181826A1 (en) 2001-12-04 2003-09-25 Dave Smith Hydrophobic/hydrophilic sample collection tip
GB0129816D0 (en) 2001-12-13 2002-01-30 The Technology Partnership Plc Testing device for chemical or biochemical analysis
US6748975B2 (en) 2001-12-26 2004-06-15 Micralyne Inc. Microfluidic valve and method of manufacturing same
US6813568B2 (en) 2002-01-09 2004-11-02 Memorial Sloan-Kettering Cancer Center System and process for microfluidics-based automated chemistry
US6758465B1 (en) 2002-03-05 2004-07-06 Smalley Steel Ring Company Wave spring with single shim end
AU2003248273A1 (en) 2002-07-12 2004-02-02 Mitsubishi Chemical Corporation Analytical chip, analytical chip unit, analyzing apparatus, method of analysis using the apparatus, and method of producing the analytical chip
US7135147B2 (en) 2002-07-26 2006-11-14 Applera Corporation Closing blade for deformable valve in a microfluidic device and method
JP2004177105A (ja) 2002-09-30 2004-06-24 Fuji Koki Corp 電動弁
US6889710B2 (en) 2002-11-15 2005-05-10 Air Products And Chemicals, Inc. Rotary sequencing valve with flexible port plate
JP3768486B2 (ja) 2003-03-20 2006-04-19 株式会社エンプラス 微小流体取扱装置
US7544506B2 (en) 2003-06-06 2009-06-09 Micronics, Inc. System and method for heating, cooling and heat cycling on microfluidic device
US20040265172A1 (en) 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
US20080257754A1 (en) 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
US6843281B1 (en) 2003-07-30 2005-01-18 Agilent Techinologies, Inc. Methods and apparatus for introducing liquids into microfluidic chambers
US7347617B2 (en) 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
US7075040B2 (en) 2003-08-21 2006-07-11 Barnstead/Thermolyne Corporation Stirring hot plate
US7682833B2 (en) 2003-09-10 2010-03-23 Abbott Point Of Care Inc. Immunoassay device with improved sample closure
US20050086830A1 (en) 2003-10-24 2005-04-28 Zukor Kenneth S. Processing cap assembly for isolating contents of a container
DE102004005193B4 (de) 2004-02-02 2006-08-24 Medion Diagnostics Gmbh Vorrichtung zur Separation einzelner Partikel von Partikel-Agglutinationen
US7432106B2 (en) 2004-03-24 2008-10-07 Applied Biosystems Inc. Liquid processing device including gas trap, and system and method
US20080176209A1 (en) 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20060099567A1 (en) 2004-04-08 2006-05-11 Biomatrica, Inc. Integration of sample storage and sample management for life science
CA2560513A1 (en) 2004-04-08 2005-12-01 Biomatrica, Inc. Integration of sample storage and sample management for life science
US8961900B2 (en) 2004-04-28 2015-02-24 Yokogawa Electric Corporation Chemical reaction cartridge, method of producing chemical reaction cartridge, and mechanism for driving chemical reaction cartridge
US20050244837A1 (en) 2004-04-28 2005-11-03 Cepheid Method and device for sample preparation control
US7887750B2 (en) 2004-05-05 2011-02-15 Bayer Healthcare Llc Analytical systems, devices, and cartridges therefor
ATE353313T1 (de) 2004-05-22 2007-02-15 Agilent Technologies Inc Bauteil eines mikrofluidischen ventils
GB0416944D0 (en) 2004-07-29 2004-09-01 Lumora Ltd Method for determining the amount of template nucleic acid present in a sample
WO2006018044A1 (en) 2004-08-18 2006-02-23 Agilent Technologies, Inc. Microfluidic assembly with coupled microfluidic devices
US7645423B2 (en) 2004-08-20 2010-01-12 International Business Machines Corporation Optical micro plugs for multichannel and multilayer pharmaceutical device
CA2577824C (en) 2004-08-25 2012-02-07 Systeme Analytique Inc. Rotary valve and analytical chromatographic system using the same
US7159848B2 (en) 2004-09-10 2007-01-09 Agilent Technologies, Inc. Clamping systems
BRPI0515317A (pt) 2004-09-20 2008-07-22 Bayer Healthcare Llc sistema e método para reposicionar uma fita de teste para diagnóstico depois da inoculação
JP2006105638A (ja) * 2004-10-01 2006-04-20 Hitachi High-Technologies Corp 化学分析装置
EP1824601B1 (en) 2004-10-18 2016-12-28 Life Technologies Corporation A device including a dissolvable structure for flow control
EP1650297B1 (en) 2004-10-19 2011-04-13 Samsung Electronics Co., Ltd. Method and apparatus for the rapid disruption of cells or viruses using micro magnetic beads and laser
AU2005299590B2 (en) 2004-10-27 2010-09-16 Cepheid Closed-system multi-stage nucleic acid amplification reactions
US8883487B2 (en) 2004-12-23 2014-11-11 Abbott Point Of Care Inc. Molecular diagnostics system and methods
US7694938B2 (en) 2005-02-17 2010-04-13 Bioquiddity, Inc. Distal rate control device
GB0503986D0 (en) 2005-02-26 2005-04-06 Secr Defence Reaction apparatus
US7964413B2 (en) 2005-03-10 2011-06-21 Gen-Probe Incorporated Method for continuous mode processing of multiple reaction receptacles in a real-time amplification assay
WO2006102516A2 (en) 2005-03-23 2006-09-28 California Institute Of Technology Devices exhibiting differential resistance to flow and methods of their use
WO2006116616A2 (en) * 2005-04-26 2006-11-02 Applera Corporation Systems and methods for multiple analyte detection
EP1920070B1 (en) 2005-05-09 2019-08-07 BioFire Diagnostics, LLC Self-contained biological analysis
JP2007020387A (ja) 2005-06-07 2007-01-25 Maguneo Giken:Kk 超伝導非接触回転装置
US20060286004A1 (en) 2005-06-15 2006-12-21 Jacobs Merrit N Containers for reducing or eliminating foaming
US7484880B2 (en) 2005-06-24 2009-02-03 V & P Scientific, Inc. Vortex stirring of vessels in a two-dimensional array
DE602005026500D1 (de) 2005-07-15 2011-04-07 Agilent Technologies Inc Vorrichtung zur Handhaben von mikrofluidischen Vorrichtungen mit einer Klemmeinrichtung
US20070128083A1 (en) 2005-07-18 2007-06-07 U.S. Genomics, Inc. Microfluidic methods and apparatuses for sample preparation and analysis
TW200714898A (en) 2005-08-02 2007-04-16 3M Innovative Properties Co Apparatus and method for detecting an analyte
US20070105206A1 (en) 2005-10-19 2007-05-10 Chang Lu Fluidic device
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US20080241910A1 (en) 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for pathogen detection
US7377291B2 (en) 2005-12-28 2008-05-27 Serveron Corporation Multiport rotary valve
JP5063616B2 (ja) 2006-02-03 2012-10-31 インテジェニックス インコーポレイテッド マイクロ流体デバイス
US20090170064A1 (en) 2006-02-27 2009-07-02 Frank G Salinas Isothermal screening of human papillomavirus related nucleic acids
US20090061450A1 (en) 2006-03-14 2009-03-05 Micronics, Inc. System and method for diagnosis of infectious diseases
JP5254949B2 (ja) 2006-03-15 2013-08-07 マイクロニクス， インコーポレイテッド 一体型の核酸アッセイ
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
ES2692380T3 (es) 2006-03-24 2018-12-03 Handylab, Inc. Método para realizar PCR con un cartucho con varias pistas
US8057882B2 (en) 2006-03-28 2011-11-15 Kobe Steel, Ltd. Membrane structure element and method for manufacturing same
US8900828B2 (en) 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
CA2649532C (en) 2006-05-02 2013-05-21 Teijin Pharma Limited Rotary-valve and adsorption separation system
US20070280856A1 (en) 2006-06-02 2007-12-06 Applera Corporation Devices and Methods for Controlling Bubble Formation in Microfluidic Devices
US20070280857A1 (en) 2006-06-02 2007-12-06 Applera Corporation Devices and Methods for Positioning Dried Reagent In Microfluidic Devices
US8187557B2 (en) 2006-07-13 2012-05-29 Cepheid Reagent reservoir system for analytical instruments
EP1878802A1 (en) 2006-07-14 2008-01-16 Roche Diagnostics GmbH Disposable device for analysing a liquid sample containing a nucleic acid with a nucleic acid amplification apparatus
WO2008024319A2 (en) 2006-08-20 2008-02-28 Codon Devices, Inc. Microfluidic devices for nucleic acid assembly
US8275243B2 (en) 2006-08-31 2012-09-25 Georgia Tech Research Corporation Method and computer program product for synchronizing, displaying, and providing access to data collected from various media
KR100758274B1 (ko) 2006-09-27 2007-09-12 한국전자통신연구원 챔버 내에서의 다중 미세 유체의 흐름을 균일화하기 위한미세 유체 소자, 및 그를 이용한 미세 유로 망
US8765076B2 (en) 2006-11-14 2014-07-01 Handylab, Inc. Microfluidic valve and method of making same
EP3391812B1 (en) 2007-01-23 2025-01-01 Ascensia Diabetes Care Holdings AG Analyte-testing device
WO2008103097A1 (en) 2007-02-22 2008-08-28 Ge Healthcare Bio-Sciences Ab Selection valve
WO2008103098A1 (en) 2007-02-22 2008-08-28 Ge Healthcare Bio-Sciences Ab Rotation valve for sample injection
US8000532B2 (en) 2007-02-28 2011-08-16 Medtronic, Inc. Digital pen to capture data in ambulatory monitored patients
WO2008108027A1 (ja) 2007-03-02 2008-09-12 Shimadzu Corporation 反応容器プレート及び反応処理装置
US8298763B2 (en) 2007-03-02 2012-10-30 Lawrence Livermore National Security, Llc Automated high-throughput flow-through real-time diagnostic system
US8434930B2 (en) 2007-03-12 2013-05-07 Hach Company Magnetically-coupled stirring apparatus with sensor and related method
WO2008121239A1 (en) 2007-03-29 2008-10-09 Response Biomedical Corporation Modular assay reader system and apparatus
CA2984820C (en) 2007-04-04 2021-12-07 Ande Corporation Plastic microfluidic separation and detection platforms
BRPI0810516A2 (pt) 2007-04-24 2014-10-07 Biomatrica Inc Armazenamento de amostra para ciência da vida
EP2152417B1 (en) 2007-05-04 2018-07-11 Opko Diagnostics, LLC Device and method for analyses in microfluidic systems
WO2008140377A1 (en) 2007-05-15 2008-11-20 Ge Healthcare Bio-Sciences Ab Random access rotary valve
AU2008251098B2 (en) 2007-05-15 2013-11-21 Ge Healthcare Bio-Sciences Ab Flow distributing valve
KR101335726B1 (ko) 2007-06-04 2013-12-04 삼성전자주식회사 면역혈청 검사 및 생화학 검사를 동시에 수행하는 디스크형미세유동장치
GB0710957D0 (en) 2007-06-07 2007-07-18 Norchip As A device for carrying out cell lysis and nucleic acid extraction
US20090047191A1 (en) 2007-06-08 2009-02-19 Gafur Zainiev Closed space disposable micro-reactor and uses thereof
CA2754884C (en) 2007-06-21 2013-04-30 Gen-Probe Incorporated Methods of concentrating an analyte
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
WO2009035847A1 (en) 2007-09-14 2009-03-19 Siemens Heathcare Diagnostics Inc. Apparatus and methods for encapsulation of in vitro diagnostic reagents
US20090081768A1 (en) 2007-09-21 2009-03-26 Applera Corporation Devices and Methods for Thermally Isolating Chambers of an Assay Card
US8268564B2 (en) * 2007-09-26 2012-09-18 President And Fellows Of Harvard College Methods and applications for stitched DNA barcodes
JP5523327B2 (ja) 2007-10-12 2014-06-18 レオニックス，インコーポレイテッド 統合型マイクロ流体デバイスおよび方法
US8304245B2 (en) 2007-11-02 2012-11-06 Children's Hospital And Research Center At Oakland Microfluidic flow lysometer device, system and method
US8191578B2 (en) 2007-11-13 2012-06-05 Mego Afek Ac Ltd. Rotary disc valve
DE102007059533A1 (de) 2007-12-06 2009-06-10 Thinxxs Microtechnology Ag Mikrofluidische Speichervorrichtung
JP5152198B2 (ja) 2007-12-19 2013-02-27 株式会社島津製作所 分注デバイス
EP2254985A4 (en) 2008-02-21 2013-09-18 Avantra Biosciences Corp ASSAYS BASED ON LIQUID CURRENT VIA ASSEMBLY
WO2009112030A1 (en) 2008-03-12 2009-09-17 Fluimedix Aps Controlled liquid handling
FR2930457B1 (fr) 2008-04-24 2010-06-25 Commissariat Energie Atomique Procede de fabrication de microcanaux reconfigurables
WO2009131677A1 (en) 2008-04-25 2009-10-29 Claros Diagnostics, Inc. Flow control in microfluidic systems
JP5244461B2 (ja) 2008-05-29 2013-07-24 株式会社東芝 化学分析装置及び分析チップ
US20120034707A1 (en) 2008-06-02 2012-02-09 Datta Sujit S Atomically precise nanoribbons and related methods
CA3060930C (en) 2008-06-06 2022-03-22 Bionanomatrix, Inc. Integrated analysis devices and related fabrication methods and analysis techniques
JP5401542B2 (ja) 2008-06-19 2014-01-29 ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 流体計量容器
DE102008002675B4 (de) 2008-06-26 2014-11-06 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Abdichteinrichtung zur Verwendung in einem Probeaufbereitungschip sowie Verfahren zu deren Herstellung
EP2143491A1 (en) 2008-07-10 2010-01-13 Carpegen GmbH Device for analysing a chemical or biological sample
US20110306072A1 (en) 2008-07-15 2011-12-15 L3 Technology Limited Assay test card
US8272401B2 (en) 2008-09-09 2012-09-25 Air Products And Chemicals, Inc. Compact pressure balanced rotary valve
EP2349566B1 (en) 2008-10-03 2016-01-06 Micronics, Inc. Microfluidic apparatus and methods for performing blood typing and crossmatching
US9316324B2 (en) 2008-10-29 2016-04-19 Agilent Technologies, Inc. Shear valve with silicon carbide member
US9501619B2 (en) 2008-11-13 2016-11-22 Cerner Innovation, Inc. Integrated medication and infusion monitoring system
US8770226B2 (en) 2008-11-13 2014-07-08 Ge Healthcare Bio-Sciences Ab Random access rotary valve
US20110232373A1 (en) 2008-12-04 2011-09-29 Vrije Universiteit Brussel Chromatographic separation device with variable length and a method for its use
DE102008055120A1 (de) 2008-12-23 2010-07-01 Qiagen Gmbh Präparation und Amplifikation von Nukleinsäuren mittels magnetischer Partikel
IT1392842B1 (it) 2008-12-29 2012-03-23 St Microelectronics Rousset Microreattore con canali di sfiato per rimuovere aria da una camera di reazione
CN102348986B (zh) 2009-01-13 2015-05-06 Fio公司 与电子设备和快速诊断测试中的测试盒结合使用的手持诊断测试设备和方法
WO2010083147A1 (en) 2009-01-14 2010-07-22 Waters Technologies Corporation Rotating valve
DE102009005874A1 (de) 2009-01-21 2010-07-22 Thinxxs Microtechnology Ag Ventil, insbesondere für ein Bauelement der Mikrofluidtechnik
KR101578149B1 (ko) 2009-01-29 2015-12-17 삼성전자주식회사 미세유체 제어용 밸브 유닛, 및 이의 제조방법
EP2391883B1 (en) 2009-01-30 2018-03-07 Micronics, Inc. Portable high gain fluorescence detection system
EP2394152B1 (en) 2009-02-03 2019-05-01 ANDE Corporation Nucleic acid purification
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
DE102009015395B4 (de) 2009-03-23 2022-11-24 Thinxxs Microtechnology Gmbh Flusszelle zur Behandlung und/oder Untersuchung eines Fluids
EP2248915B1 (en) 2009-05-05 2013-09-18 Qiagen GmbH Detection of multiple nucleic acid sequences in a reaction cartridge
EP2430195B1 (en) 2009-05-11 2019-01-23 Biomatrica, INC. Compositions and methods for biological sample storage
US8017409B2 (en) 2009-05-29 2011-09-13 Ecolab Usa Inc. Microflow analytical system
GB0910330D0 (en) 2009-06-16 2009-07-29 Univ Leiden A biological microfluidics chip and related methods
DE102009027352A1 (de) 2009-06-30 2011-01-05 Qiagen Gmbh Mikroventildichtung
US8876081B2 (en) 2009-07-13 2014-11-04 Idex Health & Science Llc Rotary shear valve assembly with a polymer insert device
KR20110027419A (ko) 2009-09-10 2011-03-16 삼성전자주식회사 유체 수용 챔버, 유체 수용 챔버를 구비한 미세 유동 장치, 및 유체 혼합 방법
CA3041540C (en) 2009-09-21 2021-08-24 Bio-Rad Laboratories, Inc. Magnetic lysis method and device
US8008080B2 (en) 2009-09-23 2011-08-30 Ecolab Usa Inc. Valve analytical system
US9320461B2 (en) 2009-09-29 2016-04-26 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
US8763640B2 (en) 2009-09-30 2014-07-01 Daikin Industries, Ltd. Rotary valve
SG169918A1 (en) 2009-10-02 2011-04-29 Fluidigm Corp Microfluidic devices with removable cover and methods of fabrication and application
DE102009048378B3 (de) 2009-10-06 2011-02-17 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Mikrofluidische Struktur
GB0919159D0 (en) 2009-11-02 2009-12-16 Sec Dep For Environment Food A Device and apparatus
EP4459241A3 (en) 2009-12-07 2025-01-01 Meso Scale Technologies, LLC. Assay cartridge reader
JP5709894B2 (ja) 2009-12-18 2015-04-30 アボット ポイント オブ ケア インコーポレイテッド 生物学的液体分析カートリッジ
EP2528687B1 (en) 2010-01-29 2018-08-22 Micronics, Inc. System comprising a host instrument and a microfluidic cartridge for assays
US9102979B2 (en) 2010-02-23 2015-08-11 Rheonix, Inc. Self-contained biological assay apparatus, methods, and applications
JP5800836B2 (ja) 2010-02-25 2015-10-28 アイデックス・ヘルス・アンド・サイエンス・リミテッド ライアビリティ カンパニーＩｄｅｘ Ｈｅａｌｔｈ ＆ Ｓｃｉｅｎｃｅ Ｌｌｃ マイクロ流体弁取り付け装置、マイクロ流体弁アセンブリ、及び、マイクロ流体弁システム
ES2914111T3 (es) 2010-03-01 2022-06-07 Ecole Polytechnique Fed Lausanne Epfl Aparato y método para detectar y medir interacciones biomoleculares
US8720036B2 (en) 2010-03-09 2014-05-13 Netbio, Inc. Unitary biochip providing sample-in to results-out processing and methods of manufacture
US20110293558A1 (en) 2010-03-22 2011-12-01 Massachusetts Institute Of Technology Material properties of t cells and related methods and compositions
EP2553473A4 (en) 2010-03-30 2016-08-10 Advanced Liquid Logic Inc DROPLET OPERATION PLATFORM
BR112012026366B1 (pt) 2010-04-16 2020-05-05 Opko Diagnostics, Llc analisador de amostras microfluídicas e método para analisar uma amostra microfluídica
US8656955B2 (en) 2010-05-20 2014-02-25 Bio-Rad Laboratories, Inc. Rotary column selector valve
WO2011150368A1 (en) 2010-05-28 2011-12-01 Arizona Board Of Regents Acting For And On Behalf Of Arziona State University Apparatus and methods for a gas dynamic virtual nozzle
CN102985827A (zh) 2010-07-09 2013-03-20 皇家飞利浦电子股份有限公司 用于选择性处理样本的系统
KR20130029128A (ko) 2010-07-23 2013-03-21 베크만 컬터, 인코포레이티드 실시간 pcr용 용기
CA2806670A1 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
GB201013267D0 (en) 2010-08-06 2010-09-22 Enigma Diagnostics Ltd Vessel and process for production thereof
US9114399B2 (en) 2010-08-31 2015-08-25 Canon U.S. Life Sciences, Inc. System and method for serial processing of multiple nucleic acid assays
TW201217783A (en) 2010-09-15 2012-05-01 Mbio Diagnostics Inc System and method for detecting multiple molecules in one assay
US8586348B2 (en) 2010-09-22 2013-11-19 California Institute Of Technology Lateral flow microfluidic assaying device and related method
US9089883B2 (en) 2010-10-07 2015-07-28 Boehringer Ingelheim International Gmbh Method for washing a microfluidic cavity
DE102010042265A1 (de) 2010-10-11 2012-04-12 PARltec GmbH Ventil, Vorrichtung mit Ventil, Verwendung des Ventils in der Vorrichtung, Mikropumpe mit Ventil, Verneblersystem mit Ventil und Dosier-/Mischvorrichtung mit Ventil
EP4024029A3 (en) 2011-01-21 2022-09-14 Labrador Diagnostics LLC Systems and methods for sample use maximization
GB201101488D0 (en) 2011-01-28 2011-03-16 Ge Healthcare Ltd Container storing freeze dried biological sample
DE102011003856B4 (de) 2011-02-09 2020-06-18 Robert Bosch Gmbh Mikrosystem für fluidische Anwendungen sowie Herstellungsverfahren und Benutzungsverfahren für ein Mikrosystem für fluidische Anwendungen
WO2013103360A1 (en) 2011-02-25 2013-07-11 The Trustees Of The University Of Pennsylvania Isothermal nucleic acid amplification reactor with integrated solid state membrane
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
GB201103917D0 (en) 2011-03-08 2011-04-20 Univ Leiden Apparatus for and methods of processing liquids or liquid based substances
US8911941B2 (en) 2011-04-14 2014-12-16 Kenneth J. Michlitsch Methods and apparatus for point-of-care nucleic acid amplification and detection
US9469871B2 (en) 2011-04-14 2016-10-18 Corporos Inc. Methods and apparatus for point-of-care nucleic acid amplification and detection
WO2012151080A1 (en) 2011-05-05 2012-11-08 Waters Technologies Corporation High pressure fluidic switching valve having variable pressure loading
US9316321B2 (en) 2011-05-09 2016-04-19 Fisher Controls International, Llc Multi-piece flow control apparatus for use with fluid valves
WO2012170560A2 (en) 2011-06-06 2012-12-13 Cornell University Microfluidic device for extracting, isolating, and analyzing dna from cells
GB201113990D0 (en) 2011-08-12 2011-09-28 Molecular Vision Ltd Flow control in a microfluidic device
US9822890B2 (en) 2011-08-30 2017-11-21 The Royal Institution For The Advancement Of Learning/Mcgill University Method and system for pre-programmed self-power microfluidic circuits
GB2494653A (en) * 2011-09-13 2013-03-20 Orreco Ltd Apparatus for blood analysis
CN102500267B (zh) 2011-11-22 2013-10-30 马荣华 机械调速磁力搅拌器
WO2013096801A1 (en) 2011-12-23 2013-06-27 Abbott Point Of Care Inc Reader devices for optical and electrochemical test devices
US8741235B2 (en) 2011-12-27 2014-06-03 Honeywell International Inc. Two step sample loading of a fluid analysis cartridge
CN103184143A (zh) 2011-12-29 2013-07-03 三星电子株式会社 固体试剂溶解器件以及使用其溶解固体试剂的方法
KR102090934B1 (ko) 2012-01-09 2020-03-19 퍼킨엘머 헬스 사이언시즈, 아이엔씨. 마이크로유체 반응기 시스템
DE102012005270A1 (de) 2012-03-10 2013-09-12 Microfluidic Chipshop Gmbh Vorrichtung zur Manipulation von Flüssigkeiten
US9333471B2 (en) 2012-04-11 2016-05-10 STAT—Diagnostica & Innovation, S.L. Fluidically integrated magnetic bead beater
EP2653216A1 (en) 2012-04-16 2013-10-23 Strategisch Initiatief Materialen vzw Baffle system and magnetic mixing system comprising such baffle system
EP2839260B1 (en) 2012-04-20 2018-07-18 Talis Biomedical Corporation Fluidic devices and systems for sample preparation or autonomous analysis
WO2013169709A1 (en) * 2012-05-08 2013-11-14 Northwestern University Cartridge for use in an automated system for isolating an analyte from a sample, and methods of use
US9063121B2 (en) 2012-05-09 2015-06-23 Stat-Diagnostica & Innovation, S.L. Plurality of reaction chambers in a test cartridge
US8857792B2 (en) 2012-05-14 2014-10-14 Fisher Controls International Llc Seal ring assemblies for use with rotary valves
EP2664914A1 (en) 2012-05-16 2013-11-20 Koninklijke Philips N.V. Magnetically assisted processing of a medium
WO2013171483A1 (en) 2012-05-18 2013-11-21 Fluorogenics Ltd Vessel of thermally conductive plastic for freeze - drying
US20130331298A1 (en) 2012-06-06 2013-12-12 Great Basin Scientific Analyzer and disposable cartridge for molecular in vitro diagnostics
JP2013256964A (ja) 2012-06-11 2013-12-26 Hitachi Appliances Inc 冷媒切替弁及びこれを備えた機器
US20150184760A1 (en) 2012-06-19 2015-07-02 Waters Technologies Corporation Injection-compression molded rotors
EP2679307B1 (de) 2012-06-28 2015-08-12 Thinxxs Microtechnology Ag Mikrospeicher, insbesondere zur Integration in eine mikrofluidische Flusszelle
ITTO20120703A1 (it) 2012-08-03 2014-02-04 Biomerieux Sa Dispositivo microfluidico monouso, cartuccia includente il dispositivo microfluidico, apparecchio per eseguire una amplificazione di acido nucleico, metodo di fabbricazione del dispositivo microfluidico, e metodo di uso del dispositivo microfluidico
US9285323B2 (en) 2012-08-08 2016-03-15 Scanadu Incorporated Quantifying color changes of chemical test pads induced concentrations of biological analytes under different lighting conditions
CN104737024B (zh) 2012-09-05 2018-01-09 塞弗德公司 流体分析系统中的通用对接站和数据门
US9573128B1 (en) 2012-09-06 2017-02-21 SciKon Innovation, Inc. Fluidics device allowing fluid flow between a plurality of wells
WO2014047523A2 (en) * 2012-09-21 2014-03-27 California Institute Of Technology Methods and devices for sample lysis
US9914968B2 (en) 2012-09-26 2018-03-13 Cepheid Honeycomb tube
US20140114215A1 (en) 2012-10-20 2014-04-24 Medtronic Ardian Luxembourg S.A.R.L. Methods for Renal Neuromodulation and Associated Systems and Devices
CN103849548A (zh) 2012-12-03 2014-06-11 三星电子株式会社 用于扩增核酸的试剂容器及其制备方法、存储试剂的方法和用于核酸分析的微流体系统
US20140197101A1 (en) 2013-01-11 2014-07-17 The Charles Stark Draper Laboratory, Inc. Systems and methods for increasing convective clearance of undesired particles in a microfluidic device
US10342909B2 (en) 2013-01-11 2019-07-09 The Charles Stark Draper Laboratory Inc. Systems and methods for increasing convective clearance of undesired particles in a microfluidic device
US10603419B2 (en) 2013-01-11 2020-03-31 The Charles Stark Draper Laboratories, Inc. Systems and methods for increasing convective clearance of undesired particles in a microfluidic device
BR112015010695B1 (pt) 2013-01-11 2023-03-07 Becton, Dickinson And Company Dispositivo microfluídico e método para realizar um ensaio de uma amostra líquida, método para formar um dispositivo microfluídico, sistema e kit
US10478543B2 (en) 2013-01-11 2019-11-19 The Charles Stark Draper Laboratory, Inc. Systems and methods for increasing convective clearance of undesired particles in a microfluidic device
US9304334B2 (en) 2013-01-21 2016-04-05 Photronics, Inc. Microfluidic thermoptic energy processor
US10376877B2 (en) 2013-02-07 2019-08-13 Sandstone Diagnostics, Inc. Automated sample processing, fluid distribution, and sedimentation assay
US10274489B2 (en) 2013-02-12 2019-04-30 Charm Sciences, Inc. Assessing assay analysis development
CA2903382A1 (en) 2013-03-01 2014-09-12 Wave 80 Biosciences, Inc. Methods and systems for enhanced microfluidic processing
AU2013202805B2 (en) 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
US9039993B2 (en) 2013-03-14 2015-05-26 Formulatrix, Inc. Microfluidic device
DE102013205412A1 (de) 2013-03-27 2014-10-02 Robert Bosch Gmbh Normal-geschlossenes Ventil für mikrofluidische Bauteile aus einem polymeren Schichtsystem sowie Verfahren
WO2014165373A1 (en) 2013-04-04 2014-10-09 Surnetics, Llc Microfluidic products with controlled fluid flow
US10350352B2 (en) 2013-05-23 2019-07-16 Turnpoint Medical Devices, Inc. Pneumatically coupled fluid control system and process with air detection and elimination
DK2821138T4 (da) 2013-07-05 2022-05-16 Thinxxs Microtechnology Gmbh Flydecelle med integreret tørstof
US10946376B2 (en) 2013-07-05 2021-03-16 Thinxxs Microtechnology Ag Carrier element for introducing a dry substance into a flow cell
GB2516667A (en) * 2013-07-29 2015-02-04 Atlas Genetics Ltd An improved cartridge, cartridge reader and method for preventing reuse
US9440233B2 (en) 2013-08-09 2016-09-13 Shark Kabushiki Kaisha Microfluidic device for serial fluidic operations
US9383020B2 (en) 2013-08-21 2016-07-05 Fisher Controls International Llc High temperature seals for use in rotary valves
WO2015031351A1 (en) 2013-08-26 2015-03-05 Diagenetix, Inc. Hardware and mobile software for operation of portable instruments for nucleic acid amplification
WO2015047190A1 (en) 2013-09-30 2015-04-02 Agency For Science, Technology And Research Microfluidic device
TW201514861A (zh) 2013-10-08 2015-04-16 Hui-Qi Gu 檢測卡匣讀取裝置及其讀取方法
US9463461B2 (en) 2013-10-25 2016-10-11 The Johns Hopkins University Self-contained cartridge and methods for integrated biochemical assay at the point-of-care
CN105873681B (zh) 2013-11-18 2019-10-11 尹特根埃克斯有限公司 用于样本分析的卡盒和仪器
US9283560B2 (en) 2013-11-22 2016-03-15 Sharp Kabushiki Kaisha Passive microfluidic metering device
JP6467419B2 (ja) 2013-11-27 2019-02-13 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 使い捨て試験ユニットをレーザ溶着するための方法
WO2015089238A1 (en) 2013-12-11 2015-06-18 Genapsys, Inc. Systems and methods for biological analysis and computation
US20150167065A1 (en) 2013-12-13 2015-06-18 General Electric Company Isothermal amplification of nucleic acids within a porous matrix
DE102013114634A1 (de) 2013-12-20 2015-06-25 Karlsruher Institut für Technologie Mikrofluidischer Bioreaktor mit modularem Aufbau zur Synthese von Zellmetaboliten, das Verfahren zur Nutzung sowie dessen Verwendung
EP3102329B1 (en) 2014-02-05 2018-10-10 Talis Biomedical Corporation Sample preparation module with stepwise pressurization mechanism
US10140654B2 (en) 2014-03-20 2018-11-27 United Parcel Service Of America, Inc. Concepts for repair and service of a consumer device using a network connection and diagnostic test
US9886750B2 (en) 2014-05-08 2018-02-06 LifeSaver Int'l Inc Electronic device for reading diagnostic test results and collecting subject data for inclusion in a local chain of evidence database and for transferring and receiving data from remote databases
US9956534B2 (en) 2014-05-17 2018-05-01 Miltenyi Biotec, Gmbh Method and device for suspending cells
EP2962758B1 (de) 2014-07-01 2017-07-19 ThinXXS Microtechnology AG Flusszelle mit einem speicherbereich und einem an einer sollbruchstelle aufschliessbaren transportkanal
GB201412043D0 (en) 2014-07-07 2014-08-20 Univ Southampton Cell positioning and analysis device
WO2016020775A1 (en) 2014-08-08 2016-02-11 Kimiya Pty. Ltd. Diagnostic, prognostic, and analytical system
JP6389328B2 (ja) 2014-09-23 2018-09-12 アイデックス・ヘルス・アンド・サイエンス・リミテッド ライアビリティ カンパニーＩｄｅｘ Ｈｅａｌｔｈ ＆ Ｓｃｉｅｎｃｅ Ｌｌｃ バネなし多位置マイクロ流体バルブアセンブリ
US10724069B2 (en) 2014-09-29 2020-07-28 Chipcare Corporation Methods and devices for cell detection
US20180264464A1 (en) 2014-11-04 2018-09-20 Grace Bio-Labs, Inc. Nitrocellulose extrusion for porous film strips
WO2016090264A1 (en) 2014-12-05 2016-06-09 Carnegie Mellon University Methods and devices for assessing cell properties under controlled gas environments
EP4029606A1 (en) 2014-12-31 2022-07-20 Visby Medical, Inc. Molecular diagnostic testing
EP3248018B1 (en) 2015-01-22 2020-01-08 Becton, Dickinson and Company Devices and systems for molecular barcoding of nucleic acid targets in single cells
GB201501705D0 (en) * 2015-02-02 2015-03-18 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
GB2531616B (en) * 2015-02-02 2017-11-22 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
SG10201501672PA (en) 2015-03-05 2016-10-28 Emage Vision Pte Ltd Inspection of sealing quality in blister packages
US20160310948A1 (en) * 2015-04-24 2016-10-27 Mesa Biotech, Inc. Fluidic Test Cassette
EP3091457B1 (en) 2015-05-02 2018-10-24 F. Hoffmann-La Roche AG Point-of-care testing system
WO2016195894A1 (en) 2015-06-05 2016-12-08 Abbott Point Of Care Inc. Systems and methods for assuring quality compliance of point-of-care single-use testing devices
TWI581862B (zh) 2015-06-16 2017-05-11 亞諾法生技股份有限公司 微流道裝置的夾持載具
US10233491B2 (en) 2015-06-19 2019-03-19 IntegenX, Inc. Valved cartridge and system
US10775370B2 (en) 2015-07-17 2020-09-15 Stat-Diagnostica & Innovation, S.L. Fluidic system for performing assays
US10463297B2 (en) 2015-08-21 2019-11-05 Medtronic Minimed, Inc. Personalized event detection methods and related devices and systems
CN205047979U (zh) 2015-09-30 2016-02-24 博奥生物集团有限公司 一种微流控阀门和微流控芯片
US9901923B2 (en) 2015-11-06 2018-02-27 The Regents Of The University Of California Mobile molecular diagnostics system with wireless communication
EP3394293B1 (en) 2015-12-22 2021-05-26 Canon U.S. Life Sciences, Inc. Sample-to-answer system for microorganism detection featuring target enrichment, amplification and detection
EP3400284A4 (en) 2016-01-08 2019-10-23 Advanced Theranostics Inc. INDEPENDENT, FULLY INTEGRATED AND CAREFUL DEVICE FOR THE DETECTION OF TARGET NUCLEIC ACIDS
US20170276599A1 (en) 2016-03-24 2017-09-28 The Board Of Regents Of The University Of Texas System Cost effective battery-powered spectrophotometric system
WO2017210334A1 (en) 2016-05-31 2017-12-07 Massachusetts Institute Of Technology Hydrodynamically controlled electric fields for high throughput transformation & high throughput parallel transformation platform
EP3475409B1 (en) 2016-06-22 2026-03-11 Becton, Dickinson and Company Modular assay reader device
CN106090311B (zh) 2016-06-27 2018-03-20 苏州麦可旺志生物技术有限公司 一种多种流体周期性定向导流装置
EP3263215B1 (de) 2016-06-30 2021-04-28 ThinXXS Microtechnology AG Vorrichtung mit einer flusszelle mit reagenzspeicher
SG10201605723YA (en) 2016-07-13 2018-02-27 Delta Electronics Intl Singapore Pte Ltd Integrated Fluidic Module
CN109892008A (zh) 2016-07-15 2019-06-14 哥特科学股份有限公司 无线感测封闭环境的性质及其装置
US20180080067A1 (en) 2016-09-14 2018-03-22 The Board Of Regents Of The University Of Texas System Rapid pertussis diagnosis on a point-of-care hybrid microfluidic biochip
US20200011847A1 (en) 2016-10-07 2020-01-09 Boehringer Ingelheim Vetmedica Gmbh Analysis system and method for testing a sample
CN106523740A (zh) 2016-12-02 2017-03-22 深圳市恒永达科技有限公司 一种用于引导液体流向的多通旋转阀
WO2018111728A1 (en) 2016-12-12 2018-06-21 Slipchip Corporation Capsule containment of dried reagents
US10331924B2 (en) 2016-12-14 2019-06-25 Reliant Immune Diagnostics, Inc. System and method for audiovisual response to retail diagnostic product
EP3342485B1 (de) 2017-01-02 2020-07-08 Thinxxs Microtechnology Ag Halterung für reagenzträgerelemente
CA3054610A1 (en) 2017-02-28 2018-09-07 Alere San Diego, Inc. Microfluidic devices and related methods
US10146909B2 (en) 2017-04-06 2018-12-04 Diassess Inc. Image-based disease diagnostics using a mobile device
EP3406340B1 (de) 2017-05-26 2021-07-07 Thinxxs Microtechnology Ag Flusszelle mit gehäusebauteil
US20210285977A1 (en) 2017-06-23 2021-09-16 Everyplace Labs, Inc. Automated Medical Diagnostic System and Method
US10610843B2 (en) 2017-11-28 2020-04-07 Talis Biomedical Corporation Magnetic mixing apparatus
US11278897B2 (en) 2017-12-28 2022-03-22 Stmicroelectronics S.R.L. Cartridge for sample preparation and molecule analysis, cartridge control machine, sample preparation system and method using the cartridge
US10527192B2 (en) 2018-02-15 2020-01-07 Talis Biomedical Corporation Rotary valve
US10046322B1 (en) 2018-03-22 2018-08-14 Talis Biomedical Corporation Reaction well for assay device
US10450616B1 (en) 2018-05-09 2019-10-22 Talis Biomedical Corporation Polynucleotides for the amplification and detection of Chlamydia trachomatis
EP3840635A4 (en) 2018-08-23 2022-05-18 Sanwa Biotech Ltd. PORTABLE DIAGNOSTIC APPARATUS AND RELATED METHOD
US10898895B2 (en) 2018-09-13 2021-01-26 Talis Biomedical Corporation Vented converging capillary biological sample port and reservoir
US10954572B2 (en) * 2019-07-25 2021-03-23 Talis Biomedical Corporation Polynucleotides for the amplification and detection of Neisseria gonorrhoeae
BR112022002794A2 (pt) 2019-08-15 2022-08-09 Childrens Hospital Philadelphia Terapia combinada de transgene e mirna derivado de íntron para tratamento de sca1
US11008627B2 (en) 2019-08-15 2021-05-18 Talis Biomedical Corporation Diagnostic system
CN110429831B (zh) 2019-08-16 2021-07-23 南京南瑞继保工程技术有限公司 换流阀
JP2022544818A (ja) 2019-08-20 2022-10-21 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 二重特異性抗体の製剤最適化

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025034038A1 (ko) * 2023-08-09 2025-02-13 경희대학교 산학협력단 유전자 분석용 카트리지 및 이를 포함하는 유전자 분석장치

Also Published As

Publication number Publication date
US11986299B2 (en) 2024-05-21
CA3146765A1 (en) 2021-02-18
WO2021030812A3 (en) 2021-04-08
US20210251540A1 (en) 2021-08-19
US20210369160A1 (en) 2021-12-02
CL2022000350A1 (es) 2022-11-18
EP4013893A2 (en) 2022-06-22
PH12022550372A1 (en) 2023-03-13
BR112022002789A2 (pt) 2022-08-09
WO2021030812A2 (en) 2021-02-18
EP4013893A4 (en) 2023-08-16
US20210047678A1 (en) 2021-02-18
US20220280081A1 (en) 2022-09-08
US11008627B2 (en) 2021-05-18
MX2022001493A (es) 2022-05-10
CO2022002783A2 (es) 2022-04-19
IL290104A (en) 2022-03-01
AU2020327367A1 (en) 2022-02-17
JP2022544530A (ja) 2022-10-19
CN114555828A (zh) 2022-05-27
US10820847B1 (en) 2020-11-03
US12310730B2 (en) 2025-05-27
JOP20220026A1 (ar) 2023-01-30

Similar Documents

Publication Publication Date Title
US12310730B2 (en) Diagnostic system
JP6392830B2 (ja) 生体関連物質測定装置
CA2988128C (en) A component of a device, a device, and a method for purifying and testing biomolecules from biological samples
EP3081301B1 (en) Apparatus and methods for integrated sample preparation, reaction and detection
US20120214167A1 (en) Apparatus for bio-automation
US20210354122A1 (en) System and cartridge for sample testing
JP2020534517A (ja) 試料の減容のための方法および装置
HK40066508A (zh) 诊断系统
US10525461B2 (en) Cartridge for purification of biological samples
CN116419800A (zh) 分子poc诊断系统中的集成的热调节和pcr
US20240017255A1 (en) Mvp cartridge and methods of use and manufacture
US20220081730A1 (en) Method, system and apparatus for respiratory testing
WO2022109480A1 (en) Method, system and apparatus for respiratory testing
WO2021046506A1 (en) Infection detection systems and methods including intermediate filtering and metering

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PC1202 Submission of document of withdrawal before decision of registration

St.27 status event code: N-1-6-B10-B11-nap-PC1202