KR20180094965A - 위장 괄약근 기능장애의 치료를 위한 sGC 자극제의 용도 - Google Patents
위장 괄약근 기능장애의 치료를 위한 sGC 자극제의 용도 Download PDFInfo
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- KR20180094965A KR20180094965A KR1020187019784A KR20187019784A KR20180094965A KR 20180094965 A KR20180094965 A KR 20180094965A KR 1020187019784 A KR1020187019784 A KR 1020187019784A KR 20187019784 A KR20187019784 A KR 20187019784A KR 20180094965 A KR20180094965 A KR 20180094965A
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- ring
- alkyl
- membered heterocyclic
- membered heteroaryl
- phenyl
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Landscapes
- Health & Medical Sciences (AREA)
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Applications Claiming Priority (3)
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| US201562266988P | 2015-12-14 | 2015-12-14 | |
| US62/266,988 | 2015-12-14 | ||
| PCT/US2016/066357 WO2017106175A2 (en) | 2015-12-14 | 2016-12-13 | USE OF sGC STIMULATORS FOR THE TREATMENT OF GASTROINTESTINAL SPHINCTER DYSFUNCTION |
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| KR20180094965A true KR20180094965A (ko) | 2018-08-24 |
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| EP (1) | EP3389655A2 (https=) |
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| AU (1) | AU2016371762A1 (https=) |
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| EA (1) | EA201891416A1 (https=) |
| IL (1) | IL259639A (https=) |
| MX (1) | MX2018007152A (https=) |
| WO (1) | WO2017106175A2 (https=) |
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| EP3194386A2 (en) * | 2014-09-17 | 2017-07-26 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| WO2017107052A1 (en) | 2015-12-22 | 2017-06-29 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase stimulators |
| EA201991147A1 (ru) | 2016-11-08 | 2019-11-29 | ЛЕЧЕНИЕ ЗАБОЛЕВАНИЙ ЦЕНТРАЛЬНОЙ НЕРВНОЙ СИСТЕМЫ С ПОМОЩЬЮ СТИМУЛЯТОРОВ sGC | |
| US11180493B2 (en) * | 2016-11-08 | 2021-11-23 | Cyclerion Therapeutics, Inc. | SGC stimulators |
| WO2018111795A2 (en) * | 2016-12-13 | 2018-06-21 | Ironwood Pharmaceuticals, Inc. | Use of sgc stimulators for the treatment of esophageal motility disorders |
| KR20210031931A (ko) * | 2018-07-11 | 2021-03-23 | 사이클리온 테라퓨틱스, 인크. | 미토콘드리아 장애의 치료를 위한 sGC 자극제의 용도 |
| WO2022265984A1 (en) * | 2021-06-14 | 2022-12-22 | Curtails Llc | Use of nep inhibitors for the treatment of gastrointestinal sphincter disorders |
| KR20250004773A (ko) * | 2022-04-20 | 2025-01-08 | 상하이 지멍 바이오파마 아이엔씨 | Rho 관련 단백질 키나아제 억제제 및 이의 제조와 응용 |
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| GB8928043D0 (en) * | 1989-12-12 | 1990-02-14 | Pfizer Ltd | Muscarinic receptor antagonists |
| US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| US5886026A (en) | 1993-07-19 | 1999-03-23 | Angiotech Pharmaceuticals Inc. | Anti-angiogenic compositions and methods of use |
| JP2928079B2 (ja) | 1994-02-14 | 1999-07-28 | 永信薬品工業股▲ふん▼有限公司 | １−（置換ベンジル）−３−（置換アリール）縮合ピラゾール類、その製造法及びその用途 |
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| DE19642255A1 (de) | 1996-10-14 | 1998-04-16 | Bayer Ag | Verwendung von 1-Benzyl-3-(substituierten-hetaryl) -kondensierten Pyrazol-Derivaten |
| IL129416A0 (en) | 1996-10-14 | 2000-02-17 | Bayer Ag | New heterocyclylmethyl-substituted pyrazol derivatives |
| DE19649460A1 (de) | 1996-11-26 | 1998-05-28 | Bayer Ag | Neue substituierte Pyrazolderivate |
| DE19744026A1 (de) | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
| US6451805B1 (en) | 1997-11-14 | 2002-09-17 | Bayer Aktiengesellschaft | Substituted pyrazole derivatives for the treatment of cardiocirculatory diseases |
| DE19830430A1 (de) | 1998-07-08 | 2000-01-13 | Hoechst Marion Roussel De Gmbh | Schwefelsubstituierte Sulfonylamino-carbonsäure-N-arylamide, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| CN1332943C (zh) | 1998-07-08 | 2007-08-22 | 萨诺费－阿文蒂斯德国有限公司 | 硫取代的磺酰基氨基羧酸n－芳基酰胺,其制备方法、用途以及含有该化合物的药物制剂 |
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| GB9824310D0 (en) | 1998-11-05 | 1998-12-30 | Univ London | Activators of soluble guanylate cyclase |
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| DE19942809A1 (de) | 1999-09-08 | 2001-03-15 | Bayer Ag | Verfahren zur Herstellung substituierter Pyrimidinderivate |
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| DE10054278A1 (de) | 2000-11-02 | 2002-05-08 | Bayer Ag | Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Osteoporose |
| DE10057751A1 (de) | 2000-11-22 | 2002-05-23 | Bayer Ag | Neue Carbamat-substituierte Pyrazolopyridinderivate |
| DE10057754A1 (de) | 2000-11-22 | 2002-05-23 | Bayer Ag | Neue Sulfonamid-substituierte Pyrazolopyridinderivate |
| JP4295505B2 (ja) | 2000-11-22 | 2009-07-15 | バイエル アクチェンゲゼルシャフト | 新規なラクタム置換ピラゾロピリジン誘導体 |
| AR031176A1 (es) | 2000-11-22 | 2003-09-10 | Bayer Ag | Nuevos derivados de pirazolpiridina sustituidos con piridina |
| JP2004521898A (ja) * | 2001-02-05 | 2004-07-22 | カム、マイケル・アルバート | 食道運動性疾患及び胃食道逆流性疾病の治療方法 |
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| GB0207104D0 (en) * | 2002-03-26 | 2002-05-08 | Pfizer Ltd | Stable hydrate of a muscarinic receptor antagonist |
| DE10216145A1 (de) | 2002-04-12 | 2003-10-23 | Bayer Ag | Verwendung von Stimulatoren der löslichen Guanylatcyclase zur Behandlung von Glaukom |
| DE10220570A1 (de) | 2002-05-08 | 2003-11-20 | Bayer Ag | Carbamat-substituierte Pyrazolopyridine |
| DE10222550A1 (de) | 2002-05-17 | 2003-11-27 | Bayer Ag | Substituierte Benzyl-pyrazolopyridine |
| DE10232571A1 (de) | 2002-07-18 | 2004-02-05 | Bayer Ag | 4-Aminosubstituierte Pyrimidinderivate |
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| DE102006020327A1 (de) | 2006-04-27 | 2007-12-27 | Bayer Healthcare Ag | Heterocyclisch substituierte, anellierte Pyrazol-Derivate und ihre Verwendung |
| DE102006021733A1 (de) | 2006-05-09 | 2007-11-22 | Bayer Healthcare Ag | 3-Tetrazolylindazole und 3-Tetrazolylpyrazolopyridine sowie ihre Verwendung |
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-
2016
- 2016-12-13 AU AU2016371762A patent/AU2016371762A1/en not_active Abandoned
- 2016-12-13 EA EA201891416A patent/EA201891416A1/ru unknown
- 2016-12-13 CN CN201680078621.9A patent/CN108463224A/zh active Pending
- 2016-12-13 EP EP16867373.9A patent/EP3389655A2/en not_active Withdrawn
- 2016-12-13 MX MX2018007152A patent/MX2018007152A/es unknown
- 2016-12-13 JP JP2018531178A patent/JP2019502686A/ja active Pending
- 2016-12-13 WO PCT/US2016/066357 patent/WO2017106175A2/en not_active Ceased
- 2016-12-13 CA CA3006764A patent/CA3006764A1/en not_active Abandoned
- 2016-12-13 US US16/061,992 patent/US20180344735A1/en not_active Abandoned
- 2016-12-13 KR KR1020187019784A patent/KR20180094965A/ko not_active Withdrawn
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2018
- 2018-05-28 IL IL259639A patent/IL259639A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA201891416A1 (ru) | 2018-12-28 |
| WO2017106175A2 (en) | 2017-06-22 |
| MX2018007152A (es) | 2018-08-15 |
| US20180344735A1 (en) | 2018-12-06 |
| JP2019502686A (ja) | 2019-01-31 |
| AU2016371762A1 (en) | 2018-06-21 |
| CN108463224A (zh) | 2018-08-28 |
| WO2017106175A3 (en) | 2017-10-19 |
| IL259639A (en) | 2018-07-31 |
| EP3389655A2 (en) | 2018-10-24 |
| CA3006764A1 (en) | 2017-06-22 |
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