KR20150115023A - 광범위한 온도에 걸쳐 활성인 프로테아제 변이형 - Google Patents

광범위한 온도에 걸쳐 활성인 프로테아제 변이형 Download PDF

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Publication number
KR20150115023A
KR20150115023A KR1020157026840A KR20157026840A KR20150115023A KR 20150115023 A KR20150115023 A KR 20150115023A KR 1020157026840 A KR1020157026840 A KR 1020157026840A KR 20157026840 A KR20157026840 A KR 20157026840A KR 20150115023 A KR20150115023 A KR 20150115023A
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South Korea
Prior art keywords
protease
sequence
protein
ala
dna
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Korean (ko)
Inventor
피테르 아우구스티누스
프리츠 구데게부르
아이루카랜 제이 파울로스
데르 란 요하네스 코넬리스 반
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다니스코 유에스 인크.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38681—Chemically modified or immobilised enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020157026840A 2006-07-18 2007-07-09 광범위한 온도에 걸쳐 활성인 프로테아제 변이형 Ceased KR20150115023A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83173206P 2006-07-18 2006-07-18
US60/831,732 2006-07-18
PCT/US2007/015642 WO2008010925A2 (en) 2006-07-18 2007-07-09 Protease variants active over a broad temperature range

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020097000871A Division KR20090031906A (ko) 2006-07-18 2007-07-09 광범위한 온도에 걸쳐 활성인 프로테아제 변이형

Publications (1)

Publication Number Publication Date
KR20150115023A true KR20150115023A (ko) 2015-10-13

Family

ID=38893328

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020157026840A Ceased KR20150115023A (ko) 2006-07-18 2007-07-09 광범위한 온도에 걸쳐 활성인 프로테아제 변이형
KR1020097000871A Abandoned KR20090031906A (ko) 2006-07-18 2007-07-09 광범위한 온도에 걸쳐 활성인 프로테아제 변이형

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020097000871A Abandoned KR20090031906A (ko) 2006-07-18 2007-07-09 광범위한 온도에 걸쳐 활성인 프로테아제 변이형

Country Status (13)

Country Link
US (6) US20080090747A1 (enExample)
EP (1) EP2059591B1 (enExample)
JP (2) JP2009543577A (enExample)
KR (2) KR20150115023A (enExample)
CN (2) CN104232365A (enExample)
AU (1) AU2007275864B2 (enExample)
BR (1) BRPI0714329B1 (enExample)
CA (1) CA2658396C (enExample)
DK (1) DK2059591T3 (enExample)
MX (1) MX2009000537A (enExample)
NZ (1) NZ573467A (enExample)
RU (1) RU2509152C2 (enExample)
WO (1) WO2008010925A2 (enExample)

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