KR20140068087A - 펩티드 나노입자 및 이의 용도 - Google Patents

펩티드 나노입자 및 이의 용도 Download PDF

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Publication number
KR20140068087A
KR20140068087A KR1020147007599A KR20147007599A KR20140068087A KR 20140068087 A KR20140068087 A KR 20140068087A KR 1020147007599 A KR1020147007599 A KR 1020147007599A KR 20147007599 A KR20147007599 A KR 20147007599A KR 20140068087 A KR20140068087 A KR 20140068087A
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KR
South Korea
Prior art keywords
peptide
trp
leu
lys
amphipathic
Prior art date
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Withdrawn
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KR1020147007599A
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English (en)
Korean (ko)
Inventor
크리스티안 디트리히
가우덴츠 다누저
Original Assignee
프레지던트 앤드 펠로우즈 오브 하바드 칼리지
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Application filed by 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 filed Critical 프레지던트 앤드 펠로우즈 오브 하바드 칼리지
Publication of KR20140068087A publication Critical patent/KR20140068087A/ko
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020147007599A 2011-08-23 2012-08-23 펩티드 나노입자 및 이의 용도 Withdrawn KR20140068087A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161526526P 2011-08-23 2011-08-23
US61/526,526 2011-08-23
PCT/US2012/052027 WO2013028843A1 (en) 2011-08-23 2012-08-23 Peptide nanoparticles and uses thereof

Publications (1)

Publication Number Publication Date
KR20140068087A true KR20140068087A (ko) 2014-06-05

Family

ID=46826904

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147007599A Withdrawn KR20140068087A (ko) 2011-08-23 2012-08-23 펩티드 나노입자 및 이의 용도

Country Status (19)

Country Link
US (1) US8828928B2 (cg-RX-API-DMAC7.html)
EP (1) EP2748182B1 (cg-RX-API-DMAC7.html)
JP (1) JP2014524477A (cg-RX-API-DMAC7.html)
KR (1) KR20140068087A (cg-RX-API-DMAC7.html)
CN (1) CN104011065B (cg-RX-API-DMAC7.html)
AU (1) AU2012298824B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014004014A2 (cg-RX-API-DMAC7.html)
CA (1) CA2845886A1 (cg-RX-API-DMAC7.html)
CL (1) CL2014000418A1 (cg-RX-API-DMAC7.html)
DK (1) DK2748182T3 (cg-RX-API-DMAC7.html)
ES (1) ES2610779T3 (cg-RX-API-DMAC7.html)
HU (1) HUE031511T2 (cg-RX-API-DMAC7.html)
IL (1) IL231005A0 (cg-RX-API-DMAC7.html)
MX (1) MX2014002062A (cg-RX-API-DMAC7.html)
PT (1) PT2748182T (cg-RX-API-DMAC7.html)
RU (1) RU2014110901A (cg-RX-API-DMAC7.html)
SG (1) SG11201400073SA (cg-RX-API-DMAC7.html)
WO (1) WO2013028843A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201401210B (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
WO2017139746A1 (en) * 2016-02-11 2017-08-17 Mark Daniels Posh inhibitor complex biomolecules and amphiphile micelles
CA3018561A1 (en) 2016-03-21 2017-09-28 Rhode Island Council On Postsecondary Education Ph-sensitive peptides
DE202017007363U1 (de) * 2016-12-16 2021-02-16 The Brigham And Women's Hospital, Inc. Zusammensetzung von Partikeln mit Eisenoxidkernen
CN106832003B (zh) * 2017-02-15 2021-01-05 中国药科大学 一种酸敏性多肽及其应用
EP3773483A4 (en) 2018-04-06 2022-01-26 Amma Therapeutics, Inc. Composition for controlled release of therapeutic agents
US12319711B2 (en) 2019-09-20 2025-06-03 Northwestern University Spherical nucleic acids with tailored and active protein coronae
US12378560B2 (en) 2019-10-29 2025-08-05 Northwestern University Sequence multiplicity within spherical nucleic acids
CN114516819B (zh) * 2022-02-25 2024-02-27 顺毅宜昌化工有限公司 一种n,n’-二乙酰基肼的制备方法
WO2023244536A2 (en) * 2022-06-13 2023-12-21 Neubase Therapeutics, Inc. Oligonucleotide analogue formulations
CN116004221B (zh) * 2022-12-15 2023-12-19 湖南卓润生物科技有限公司 环肽的新应用、吖啶标记复合物与制备方法、检测试剂盒

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
US3270960A (en) 1964-09-11 1966-09-06 Sperry Rand Corp Fluid sensor
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3872925A (en) 1973-04-24 1975-03-25 Gearhart Owen Industries Through-tubing bridge plug
US3842067A (en) 1973-07-27 1974-10-15 American Home Prod Synthesis of(des-asn5)-srif and intermediates
JPS5726506B2 (cg-RX-API-DMAC7.html) 1974-03-08 1982-06-04
US4105603A (en) 1977-03-28 1978-08-08 The Salk Institute For Biological Studies Peptides which effect release of hormones
US4511390A (en) 1983-06-10 1985-04-16 E. I. Du Pont De Nemours And Company Aralkylcarbamoyl peptide alcohols
US5643873A (en) 1992-05-06 1997-07-01 Affymax Technologies N.V. Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1
US5625048A (en) 1994-11-10 1997-04-29 The Regents Of The University Of California Modified green fluorescent proteins
US5654276A (en) 1995-06-07 1997-08-05 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
FR2736642B1 (fr) 1995-07-10 1997-09-12 Pasteur Institut Immunovecteurs, notamment anticorps et fragments d'anticorps utilisables pour le transport intracellulaire et intranucleaire de principes biologiquement actifs notamment d'haptenes, de proteines et d'acides nucleiques
US6124128A (en) 1996-08-16 2000-09-26 The Regents Of The University Of California Long wavelength engineered fluorescent proteins
WO2001009191A1 (en) 1999-08-02 2001-02-08 Synt:Em S.A. Computational design methods for making molecular mimetics
CA2439400A1 (en) 2001-02-26 2002-09-06 The Regents Of The University Of California Non-oligomerizing tandem fluorescent proteins
CA2572964C (en) 2004-07-06 2018-03-06 3D Matrix, Inc. Purified amphiphilic peptide compositions and uses thereof
JP6088123B2 (ja) * 2008-02-01 2017-03-01 アルファ−オー・ペプチドズ・アーゲーＡｌｐｈａ−Ｏ Ｐｅｐｔｉｄｅｓ Ａｇ ワクチンとして有用な自己会合ペプチドナノ粒子
US20110112040A1 (en) * 2008-04-28 2011-05-12 President And Fellows Of Harvard College Supercharged proteins for cell penetration

Also Published As

Publication number Publication date
MX2014002062A (es) 2014-05-28
CN104011065B (zh) 2017-06-30
US20130064895A1 (en) 2013-03-14
IL231005A0 (en) 2014-03-31
SG11201400073SA (en) 2014-03-28
CA2845886A1 (en) 2013-02-28
AU2012298824A1 (en) 2014-03-20
EP2748182A1 (en) 2014-07-02
RU2014110901A (ru) 2015-09-27
CL2014000418A1 (es) 2014-07-25
US8828928B2 (en) 2014-09-09
ES2610779T3 (es) 2017-05-03
NZ622045A (en) 2016-02-26
ZA201401210B (en) 2015-12-23
WO2013028843A1 (en) 2013-02-28
AU2012298824B2 (en) 2017-06-01
PT2748182T (pt) 2017-01-20
DK2748182T3 (en) 2017-02-06
JP2014524477A (ja) 2014-09-22
CN104011065A (zh) 2014-08-27
EP2748182B1 (en) 2016-10-19
BR112014004014A2 (pt) 2020-10-27
HUE031511T2 (en) 2017-07-28

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20140321

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid