KR20140034861A - 디펩티딜 펩티다제-iv 억제제의 신규한 결정질 형태 - Google Patents
디펩티딜 펩티다제-iv 억제제의 신규한 결정질 형태 Download PDFInfo
- Publication number
- KR20140034861A KR20140034861A KR1020137034362A KR20137034362A KR20140034861A KR 20140034861 A KR20140034861 A KR 20140034861A KR 1020137034362 A KR1020137034362 A KR 1020137034362A KR 20137034362 A KR20137034362 A KR 20137034362A KR 20140034861 A KR20140034861 A KR 20140034861A
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- South Korea
- Prior art keywords
- crystalline form
- crystalline
- difluorophenyl
- pyran
- methylsulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003603 dipeptidyl peptidase IV inhibitor Substances 0.000 title description 4
- -1 2,5-difluorophenyl Chemical group 0.000 claims abstract description 39
- 238000000034 method Methods 0.000 claims abstract description 26
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- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims abstract description 22
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 claims abstract description 20
- 238000011282 treatment Methods 0.000 claims abstract description 17
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| WO2013003249A1 (en) * | 2011-06-29 | 2013-01-03 | Merck Sharp & Dohme Corp. | Novel crystalline forms of a dipeptidyl peptidase-iv inhibitor |
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