KR20140014388A - 카복스아미드 화합물 및 칼파인 억제제로서의 이의 용도 - Google Patents

카복스아미드 화합물 및 칼파인 억제제로서의 이의 용도 Download PDF

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KR20140014388A
KR20140014388A KR20117029220A KR20117029220A KR20140014388A KR 20140014388 A KR20140014388 A KR 20140014388A KR 20117029220 A KR20117029220 A KR 20117029220A KR 20117029220 A KR20117029220 A KR 20117029220A KR 20140014388 A KR20140014388 A KR 20140014388A
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alkyl
carboxamide
rac
dioxo
aryl
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Korean (ko)
Inventor
헬무트 마크
안드레아스 크링
카트야 얀토스
아힘 모엘러
빌프리트 호른베르거
찰스 더블유. 허친스
Original Assignee
애브비 인코포레이티드
아비에 도이치란트 게엠베하 운트 콤파니 카게
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Application filed by 애브비 인코포레이티드, 아비에 도이치란트 게엠베하 운트 콤파니 카게 filed Critical 애브비 인코포레이티드
Publication of KR20140014388A publication Critical patent/KR20140014388A/ko
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • AIDS & HIV (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Hydrogenated Pyridines (AREA)
KR20117029220A 2009-05-07 2010-05-06 카복스아미드 화합물 및 칼파인 억제제로서의 이의 용도 Ceased KR20140014388A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17613809P 2009-05-07 2009-05-07
US61/176,138 2009-05-07
US28975309P 2009-12-23 2009-12-23
US61/289,753 2009-12-23
PCT/EP2010/056166 WO2010128102A1 (en) 2009-05-07 2010-05-06 Carboxamide compounds and their use as calpain inhibitors

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KR20140014388A true KR20140014388A (ko) 2014-02-06

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