ATE239698T1 - Angiogenese hemmer - Google Patents
Angiogenese hemmerInfo
- Publication number
- ATE239698T1 ATE239698T1 AT99106760T AT99106760T ATE239698T1 AT E239698 T1 ATE239698 T1 AT E239698T1 AT 99106760 T AT99106760 T AT 99106760T AT 99106760 T AT99106760 T AT 99106760T AT E239698 T1 ATE239698 T1 AT E239698T1
- Authority
- AT
- Austria
- Prior art keywords
- angiogenesis inhibitors
- angiogenesis
- inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27748595 | 1995-10-25 | ||
JP24804696 | 1996-09-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE239698T1 true ATE239698T1 (de) | 2003-05-15 |
Family
ID=26538555
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96116994T ATE230275T1 (de) | 1995-10-25 | 1996-10-23 | Angiogense-inhibitor |
AT99102501T ATE230389T1 (de) | 1995-10-25 | 1996-10-23 | Angiogenese inhibitoren |
AT99106760T ATE239698T1 (de) | 1995-10-25 | 1996-10-23 | Angiogenese hemmer |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96116994T ATE230275T1 (de) | 1995-10-25 | 1996-10-23 | Angiogense-inhibitor |
AT99102501T ATE230389T1 (de) | 1995-10-25 | 1996-10-23 | Angiogenese inhibitoren |
Country Status (13)
Country | Link |
---|---|
US (2) | US6057290A (de) |
EP (2) | EP0927716B1 (de) |
AR (1) | AR004694A1 (de) |
AT (3) | ATE230275T1 (de) |
AU (1) | AU716495B2 (de) |
BR (1) | BR9605267A (de) |
CA (1) | CA2188817C (de) |
DE (3) | DE69628050T2 (de) |
ES (2) | ES2190139T3 (de) |
HU (1) | HUP9602943A3 (de) |
MX (1) | MX9605156A (de) |
NO (1) | NO964514L (de) |
PL (1) | PL316669A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0838460A4 (de) * | 1995-07-13 | 1998-11-04 | Senju Pharma Co | Piperazinderivate und ihre anwendung |
US6214800B1 (en) * | 1995-10-25 | 2001-04-10 | Senju Pharmaceutical Co., Ltd. | Angiogenesis inhibitor |
DE19718826A1 (de) * | 1997-05-05 | 1998-11-12 | Marion S Dr Eckmiller | Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung |
ES2201524T3 (es) * | 1997-09-04 | 2004-03-16 | Nippon Chemiphar Co., Ltd. | Derivados de epoxisuccinamida. |
US6015787A (en) * | 1997-11-04 | 2000-01-18 | New England Medical Center Hospitals, Inc. | Cell-permeable protein inhibitors of calpain |
KR20010041605A (ko) * | 1998-03-05 | 2001-05-25 | 요시다 쇼지 | 안저 조직 세포병리와 관련된 질환의 예방 및 치료용 제약조성물 |
EP1064021B1 (de) | 1998-03-20 | 2004-09-08 | Senju Pharmaceutical Co., Ltd. | Verwendung von cysteinprotease inhibitoren zur herstellung eines arzneimittels zur vorgbeugung und behandlung von gehirngewebezerrütung infolge hypertensive enzephalopathie oder encephalothlipsis |
GB9819860D0 (en) * | 1998-09-12 | 1998-11-04 | Zeneca Ltd | Chemical compounds |
DE69930764D1 (de) | 1998-12-23 | 2006-05-18 | G D Searle Llc St Louis | Verwendung von cyclooxygenase-2 inhibitor celecoxib und capecitabine zur kombinationsbehandlung von neoplasia |
WO2000058280A1 (fr) * | 1999-03-26 | 2000-10-05 | Shionogi & Co., Ltd. | Derives de sulfonamide carbocyclique |
KR20010001270A (ko) * | 1999-06-03 | 2001-01-05 | 복성해 | 혈관신생을 억제하는 새로운 이소쿠마린 유도체 |
WO2001026648A1 (fr) | 1999-10-13 | 2001-04-19 | Senju Pharmaceutical Co., Ltd. | Preparation d'adhesif a usage ophtalmique pour l'absorption par voie percutanee |
AU1735001A (en) * | 1999-12-10 | 2001-06-18 | Senju Pharmaceutical Co., Ltd. | Cyclodextrin-containing pharmaceutical composition |
AU2001292287A1 (en) * | 2000-10-26 | 2002-05-06 | Senju Pharmaceutical Co. Ltd. | Drug composition comprising dipeptydyl aldehyde derivative |
AU2002221066A1 (en) * | 2000-12-12 | 2002-06-24 | Senju Pharmaceutical Co. Ltd. | Hydrazone derivatives and use thereof in medicines |
CZ20033296A3 (cs) * | 2001-06-06 | 2004-04-14 | Eli Lilly And Company | Benzoylsulfonamidy a sulfonylbenzamidiny jako protinádorové sloučeniny |
US7115607B2 (en) * | 2001-07-25 | 2006-10-03 | Amgen Inc. | Substituted piperazinyl amides and methods of use |
WO2003078415A1 (fr) * | 2002-03-15 | 2003-09-25 | Senju Pharmaceutical Co., Ltd. | Derive de l'hemiacetal cyclique et son utilisation |
EP1491537B1 (de) * | 2002-03-29 | 2010-07-07 | Senju Pharmaceutical Co., Ltd. | Hydroxymorpholinonderivat und dessen medizinische verwendung |
EP1354586A1 (de) * | 2002-04-20 | 2003-10-22 | Aventis Pharma Deutschland GmbH | Verwendung von Hydroxypyridon Derivaten zur Wundheilung |
AU2003248059A1 (en) | 2002-07-22 | 2004-02-09 | Senju Pharmaceutical Co., Ltd. | NOVEL Alpha-KETOAMIDE DERIVATIVE AND USE THEREOF |
GB0314262D0 (en) | 2003-06-19 | 2003-07-23 | Univ Nottingham Trent | Novel compounds and methods of using the same |
US7615556B2 (en) | 2006-01-27 | 2009-11-10 | Bristol-Myers Squibb Company | Piperazinyl derivatives as modulators of chemokine receptor activity |
US8236798B2 (en) | 2009-05-07 | 2012-08-07 | Abbott Gmbh & Co. Kg | Carboxamide compounds and their use as calpain inhibitors |
JPWO2011105070A1 (ja) | 2010-02-25 | 2013-06-20 | パナソニック株式会社 | 需給制御装置、需給制御方法、およびプログラム |
EP2593089B1 (de) | 2010-07-14 | 2018-04-04 | Senju Pharmaceutical Co., Ltd. | Feste dispersion eines alfa-ketoamid-derivats |
GB201218084D0 (en) * | 2012-10-09 | 2012-11-21 | Univ Aston | Novel compounds and methods for use in medicine |
GB201220474D0 (en) * | 2012-11-14 | 2012-12-26 | Sagetis Biotech Sl | Polypeptides |
WO2019217410A1 (en) * | 2018-05-07 | 2019-11-14 | Neuro Theranostics, Inc. | Compositions and methods for treating traumatic brain injury |
US20240150396A1 (en) * | 2021-03-03 | 2024-05-09 | The Texas A&M University System | Inhibitors of cysteine proteases |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50137951A (de) | 1974-04-27 | 1975-11-01 | ||
JPS5754157A (en) | 1980-09-19 | 1982-03-31 | Nippon Kayaku Co Ltd | L-argininal derivative and its preparation |
PT84170B (pt) * | 1986-01-24 | 1989-03-30 | Sanofi Sa | Processo para a preparacao de derivados n alfa-substituidos das n alfa-aril-sulfonilaminoacil d-amidinofenil-alaninamidas |
JP2536754B2 (ja) * | 1987-05-08 | 1996-09-18 | 日本ケミファ株式会社 | ピペラジン誘導体 |
JPH0832698B2 (ja) * | 1987-05-08 | 1996-03-29 | 日本ケミファ株式会社 | ピペラジン誘導体 |
JP2701932B2 (ja) | 1989-04-10 | 1998-01-21 | サントリー株式会社 | タンパク質分解酵素阻害剤 |
US5510531A (en) | 1989-04-10 | 1996-04-23 | Suntory Limited | Proteinase inhibitor |
DE69024400T2 (de) * | 1989-04-28 | 1996-06-27 | Takara Shuzo Co | Dem menschlichen Calpastatin ähnliches Polypeptid |
ZA921279B (en) | 1991-02-22 | 1993-08-23 | Du Pont Merck Pharma | Substituted alpha-aminoaldehydes and derivatives |
EP0504938A3 (en) * | 1991-03-22 | 1993-04-14 | Suntory Limited | Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient |
CA2071621C (en) * | 1991-06-19 | 1996-08-06 | Ahihiko Hosoda | Aldehyde derivatives |
JP2848232B2 (ja) | 1993-02-19 | 1999-01-20 | 武田薬品工業株式会社 | アルデヒド誘導体 |
US5607831A (en) | 1993-03-25 | 1997-03-04 | The United States Of America As Represented By The Department Of Health And Human Services | In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death |
US5658885A (en) | 1993-04-27 | 1997-08-19 | The Dupont Merck Pharmaceutical Company | Amidino and guanidino substituted boronic acid inhibitors of trypsin-like enzymes |
JP3599287B2 (ja) * | 1993-04-28 | 2004-12-08 | 三菱化学株式会社 | スルホンアミド誘導体 |
WO1996010014A1 (en) * | 1994-09-27 | 1996-04-04 | Takeda Chemical Industries, Ltd. | Aldehyde derivatives as upsteine protease inhibitors |
US5614649A (en) | 1994-11-14 | 1997-03-25 | Cephalon, Inc. | Multicatalytic protease inhibitors |
EP0731107A1 (de) * | 1995-02-13 | 1996-09-11 | Takeda Chemical Industries, Ltd. | Herstellung von Aldehyd-Derivaten |
JPH11505532A (ja) | 1995-05-10 | 1999-05-21 | カイロサイエンス・リミテッド | 金属プロテアーゼとtnfの放出を抑制するペプチド化合物およびその治療的使用 |
EP0838460A4 (de) * | 1995-07-13 | 1998-11-04 | Senju Pharma Co | Piperazinderivate und ihre anwendung |
KR100490807B1 (ko) | 1995-11-28 | 2005-10-14 | 세파론, 인코포레이티드 | 시스테인및세린프로테아제의d-아미노산함유억제제 |
-
1996
- 1996-10-23 AT AT96116994T patent/ATE230275T1/de not_active IP Right Cessation
- 1996-10-23 ES ES99102501T patent/ES2190139T3/es not_active Expired - Lifetime
- 1996-10-23 AT AT99102501T patent/ATE230389T1/de not_active IP Right Cessation
- 1996-10-23 ES ES99106760T patent/ES2193615T3/es not_active Expired - Lifetime
- 1996-10-23 DE DE69628050T patent/DE69628050T2/de not_active Expired - Lifetime
- 1996-10-23 AT AT99106760T patent/ATE239698T1/de not_active IP Right Cessation
- 1996-10-23 DE DE69625575T patent/DE69625575T2/de not_active Expired - Lifetime
- 1996-10-23 DE DE69625622T patent/DE69625622T2/de not_active Expired - Lifetime
- 1996-10-23 EP EP99106760A patent/EP0927716B1/de not_active Expired - Lifetime
- 1996-10-23 EP EP96116994A patent/EP0771565B1/de not_active Expired - Lifetime
- 1996-10-24 PL PL96316669A patent/PL316669A1/xx unknown
- 1996-10-24 HU HU9602943A patent/HUP9602943A3/hu unknown
- 1996-10-24 US US08/740,069 patent/US6057290A/en not_active Expired - Lifetime
- 1996-10-24 NO NO964514A patent/NO964514L/no not_active Application Discontinuation
- 1996-10-24 MX MX9605156A patent/MX9605156A/es unknown
- 1996-10-24 CA CA2188817A patent/CA2188817C/en not_active Expired - Fee Related
- 1996-10-24 AU AU70384/96A patent/AU716495B2/en not_active Ceased
- 1996-10-25 BR BR9605267A patent/BR9605267A/pt not_active Application Discontinuation
- 1996-10-25 AR ARP960104906A patent/AR004694A1/es unknown
-
1999
- 1999-02-03 US US09/243,822 patent/US6551999B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU7038496A (en) | 1997-05-01 |
US6551999B1 (en) | 2003-04-22 |
EP0927716A1 (de) | 1999-07-07 |
ES2190139T3 (es) | 2003-07-16 |
NO964514L (no) | 1997-04-28 |
US6057290A (en) | 2000-05-02 |
EP0771565A3 (de) | 1998-11-04 |
DE69625622D1 (de) | 2003-02-06 |
PL316669A1 (en) | 1997-04-28 |
DE69625575T2 (de) | 2003-09-25 |
ES2193615T3 (es) | 2003-11-01 |
ATE230275T1 (de) | 2003-01-15 |
EP0771565A2 (de) | 1997-05-07 |
EP0927716B1 (de) | 2003-05-07 |
DE69625575D1 (de) | 2003-02-06 |
DE69625622T2 (de) | 2003-08-14 |
DE69628050D1 (de) | 2003-06-12 |
BR9605267A (pt) | 1998-07-21 |
AR004694A1 (es) | 1999-03-10 |
HUP9602943A2 (en) | 1997-08-28 |
ATE230389T1 (de) | 2003-01-15 |
CA2188817A1 (en) | 1997-04-26 |
AU716495B2 (en) | 2000-02-24 |
CA2188817C (en) | 2010-01-26 |
DE69628050T2 (de) | 2004-04-01 |
HUP9602943A3 (en) | 1998-03-02 |
MX9605156A (es) | 1998-05-31 |
NO964514D0 (no) | 1996-10-24 |
EP0771565B1 (de) | 2003-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |