ATE230389T1 - Angiogenese inhibitoren - Google Patents
Angiogenese inhibitorenInfo
- Publication number
- ATE230389T1 ATE230389T1 AT99102501T AT99102501T ATE230389T1 AT E230389 T1 ATE230389 T1 AT E230389T1 AT 99102501 T AT99102501 T AT 99102501T AT 99102501 T AT99102501 T AT 99102501T AT E230389 T1 ATE230389 T1 AT E230389T1
- Authority
- AT
- Austria
- Prior art keywords
- angiogenesis inhibitors
- angiogenesis
- inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27748595 | 1995-10-25 | ||
JP24804696 | 1996-09-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE230389T1 true ATE230389T1 (de) | 2003-01-15 |
Family
ID=26538555
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99106760T ATE239698T1 (de) | 1995-10-25 | 1996-10-23 | Angiogenese hemmer |
AT96116994T ATE230275T1 (de) | 1995-10-25 | 1996-10-23 | Angiogense-inhibitor |
AT99102501T ATE230389T1 (de) | 1995-10-25 | 1996-10-23 | Angiogenese inhibitoren |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99106760T ATE239698T1 (de) | 1995-10-25 | 1996-10-23 | Angiogenese hemmer |
AT96116994T ATE230275T1 (de) | 1995-10-25 | 1996-10-23 | Angiogense-inhibitor |
Country Status (13)
Country | Link |
---|---|
US (2) | US6057290A (de) |
EP (2) | EP0771565B1 (de) |
AR (1) | AR004694A1 (de) |
AT (3) | ATE239698T1 (de) |
AU (1) | AU716495B2 (de) |
BR (1) | BR9605267A (de) |
CA (1) | CA2188817C (de) |
DE (3) | DE69625622T2 (de) |
ES (2) | ES2190139T3 (de) |
HU (1) | HUP9602943A3 (de) |
MX (1) | MX9605156A (de) |
NO (1) | NO964514L (de) |
PL (1) | PL316669A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2226740A1 (en) * | 1995-07-13 | 1997-01-30 | Mitsuyoshi Azuma | Piperazine derivative and its uses |
US6214800B1 (en) * | 1995-10-25 | 2001-04-10 | Senju Pharmaceutical Co., Ltd. | Angiogenesis inhibitor |
DE19718826A1 (de) * | 1997-05-05 | 1998-11-12 | Marion S Dr Eckmiller | Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung |
ES2201524T3 (es) * | 1997-09-04 | 2004-03-16 | Nippon Chemiphar Co., Ltd. | Derivados de epoxisuccinamida. |
US6015787A (en) * | 1997-11-04 | 2000-01-18 | New England Medical Center Hospitals, Inc. | Cell-permeable protein inhibitors of calpain |
DE69939075D1 (de) | 1998-03-05 | 2008-08-21 | Senju Pharma Co | Pharmazeutische Zusammenstellung zur Vorbeugung und Behandlung von mit Zellkrankheiten des Augenhintergrundes zusammenhängenden Krankheiten |
KR20010041967A (ko) * | 1998-03-20 | 2001-05-25 | 요시다 쇼지 | 뇌조직 장애를 예방 및 치료하기 위한 시스테인프로테아제 억제제 함유 약제학적 조성물 |
GB9819860D0 (en) * | 1998-09-12 | 1998-11-04 | Zeneca Ltd | Chemical compounds |
EP1140194A2 (de) | 1998-12-23 | 2001-10-10 | G.D. SEARLE & CO. | Verwendung von einen cyclooxygenase-2 inhibitor, einen matrix metalloproteinase-inhibitor, einen antineoplastische wirkstoff und wahlweise bestrahlung als kombinationsterapie von neoplasie |
AU3196300A (en) * | 1999-03-26 | 2000-10-16 | Shionogi & Co., Ltd. | Carbocyclic sulfonamide derivatives |
KR20010001270A (ko) | 1999-06-03 | 2001-01-05 | 복성해 | 혈관신생을 억제하는 새로운 이소쿠마린 유도체 |
US7052714B1 (en) | 1999-10-13 | 2006-05-30 | Senju Pharmaceutical Co., Ltd | Ophthalmic adhesive preparations for percutaneous adsorption |
AU1735001A (en) * | 1999-12-10 | 2001-06-18 | Senju Pharmaceutical Co., Ltd. | Cyclodextrin-containing pharmaceutical composition |
JPWO2002034252A1 (ja) * | 2000-10-26 | 2004-03-04 | 千寿製薬株式会社 | ジペプチジルアルデヒド誘導体含有医薬組成物 |
AU2002221066A1 (en) * | 2000-12-12 | 2002-06-24 | Senju Pharmaceutical Co. Ltd. | Hydrazone derivatives and use thereof in medicines |
CZ20033296A3 (cs) * | 2001-06-06 | 2004-04-14 | Eli Lilly And Company | Benzoylsulfonamidy a sulfonylbenzamidiny jako protinádorové sloučeniny |
US7115607B2 (en) * | 2001-07-25 | 2006-10-03 | Amgen Inc. | Substituted piperazinyl amides and methods of use |
WO2003078415A1 (fr) * | 2002-03-15 | 2003-09-25 | Senju Pharmaceutical Co., Ltd. | Derive de l'hemiacetal cyclique et son utilisation |
AU2003236180A1 (en) | 2002-03-29 | 2003-10-13 | Senju Pharmaceutical Co., Ltd. | Hydroxymorpholinone derivative and medicinal use thereof |
EP1354586A1 (de) * | 2002-04-20 | 2003-10-22 | Aventis Pharma Deutschland GmbH | Verwendung von Hydroxypyridon Derivaten zur Wundheilung |
ES2332363T3 (es) * | 2002-07-22 | 2010-02-03 | Senju Pharmaceutical Co., Ltd. | Nuevos derivados de alfa-cetoamida y su uso. |
GB0314262D0 (en) | 2003-06-19 | 2003-07-23 | Univ Nottingham Trent | Novel compounds and methods of using the same |
US7615556B2 (en) * | 2006-01-27 | 2009-11-10 | Bristol-Myers Squibb Company | Piperazinyl derivatives as modulators of chemokine receptor activity |
US8236798B2 (en) | 2009-05-07 | 2012-08-07 | Abbott Gmbh & Co. Kg | Carboxamide compounds and their use as calpain inhibitors |
EP2541716A1 (de) | 2010-02-25 | 2013-01-02 | Panasonic Corporation | Bedarfs- und ausgabesteuerungsvorrichtung, bedarfs- und ausgabesteuerungsverfahren sowie programm dafür |
CN103052382B (zh) | 2010-07-14 | 2014-10-22 | 千寿制药株式会社 | α-酮酰胺衍生物的固体分散体 |
GB201218084D0 (en) * | 2012-10-09 | 2012-11-21 | Univ Aston | Novel compounds and methods for use in medicine |
GB201220474D0 (en) * | 2012-11-14 | 2012-12-26 | Sagetis Biotech Sl | Polypeptides |
WO2019217410A1 (en) * | 2018-05-07 | 2019-11-14 | Neuro Theranostics, Inc. | Compositions and methods for treating traumatic brain injury |
WO2022187491A1 (en) * | 2021-03-03 | 2022-09-09 | The Texas A& M University System | Inhibitors of cysteine proteases |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50137951A (de) | 1974-04-27 | 1975-11-01 | ||
JPS5754157A (en) | 1980-09-19 | 1982-03-31 | Nippon Kayaku Co Ltd | L-argininal derivative and its preparation |
PT84170B (pt) * | 1986-01-24 | 1989-03-30 | Sanofi Sa | Processo para a preparacao de derivados n alfa-substituidos das n alfa-aril-sulfonilaminoacil d-amidinofenil-alaninamidas |
JP2536754B2 (ja) * | 1987-05-08 | 1996-09-18 | 日本ケミファ株式会社 | ピペラジン誘導体 |
JPH0832698B2 (ja) * | 1987-05-08 | 1996-03-29 | 日本ケミファ株式会社 | ピペラジン誘導体 |
US5510531A (en) | 1989-04-10 | 1996-04-23 | Suntory Limited | Proteinase inhibitor |
JP2701932B2 (ja) * | 1989-04-10 | 1998-01-21 | サントリー株式会社 | タンパク質分解酵素阻害剤 |
DE69024400T2 (de) * | 1989-04-28 | 1996-06-27 | Takara Shuzo Co | Dem menschlichen Calpastatin ähnliches Polypeptid |
WO1992014696A2 (en) | 1991-02-22 | 1992-09-03 | The Du Pont Merck Pharmaceutical Company | SUBSTITUTED α-AMINOALDEHYDES AND DERIVATIVES |
EP0504938A3 (en) * | 1991-03-22 | 1993-04-14 | Suntory Limited | Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient |
CA2071621C (en) * | 1991-06-19 | 1996-08-06 | Ahihiko Hosoda | Aldehyde derivatives |
JP2848232B2 (ja) | 1993-02-19 | 1999-01-20 | 武田薬品工業株式会社 | アルデヒド誘導体 |
US5607831A (en) | 1993-03-25 | 1997-03-04 | The United States Of America As Represented By The Department Of Health And Human Services | In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death |
US5658885A (en) | 1993-04-27 | 1997-08-19 | The Dupont Merck Pharmaceutical Company | Amidino and guanidino substituted boronic acid inhibitors of trypsin-like enzymes |
JP3599287B2 (ja) * | 1993-04-28 | 2004-12-08 | 三菱化学株式会社 | スルホンアミド誘導体 |
CA2196182A1 (en) * | 1994-09-27 | 1996-04-04 | Takashi Sohda | Aldehyde derivatives as upsteine protease inhibitors |
US5614649A (en) | 1994-11-14 | 1997-03-25 | Cephalon, Inc. | Multicatalytic protease inhibitors |
EP0731107A1 (de) * | 1995-02-13 | 1996-09-11 | Takeda Chemical Industries, Ltd. | Herstellung von Aldehyd-Derivaten |
AU706064B2 (en) | 1995-05-10 | 1999-06-10 | Darwin Discovery Limited | Peptide compounds which inhibit metalloproteinase and TNF liberation, and their therapeutic use |
CA2226740A1 (en) * | 1995-07-13 | 1997-01-30 | Mitsuyoshi Azuma | Piperazine derivative and its uses |
EP0910564B1 (de) | 1995-11-28 | 2007-10-31 | Cephalon, Inc. | Aus d-aminosäuren abgeleitete cystein- und serinproteasehemmer |
-
1996
- 1996-10-23 DE DE69625622T patent/DE69625622T2/de not_active Expired - Lifetime
- 1996-10-23 AT AT99106760T patent/ATE239698T1/de not_active IP Right Cessation
- 1996-10-23 DE DE69625575T patent/DE69625575T2/de not_active Expired - Lifetime
- 1996-10-23 ES ES99102501T patent/ES2190139T3/es not_active Expired - Lifetime
- 1996-10-23 AT AT96116994T patent/ATE230275T1/de not_active IP Right Cessation
- 1996-10-23 EP EP96116994A patent/EP0771565B1/de not_active Expired - Lifetime
- 1996-10-23 EP EP99106760A patent/EP0927716B1/de not_active Expired - Lifetime
- 1996-10-23 AT AT99102501T patent/ATE230389T1/de not_active IP Right Cessation
- 1996-10-23 ES ES99106760T patent/ES2193615T3/es not_active Expired - Lifetime
- 1996-10-23 DE DE69628050T patent/DE69628050T2/de not_active Expired - Lifetime
- 1996-10-24 CA CA2188817A patent/CA2188817C/en not_active Expired - Fee Related
- 1996-10-24 PL PL96316669A patent/PL316669A1/xx unknown
- 1996-10-24 NO NO964514A patent/NO964514L/no not_active Application Discontinuation
- 1996-10-24 US US08/740,069 patent/US6057290A/en not_active Expired - Lifetime
- 1996-10-24 HU HU9602943A patent/HUP9602943A3/hu unknown
- 1996-10-24 AU AU70384/96A patent/AU716495B2/en not_active Ceased
- 1996-10-24 MX MX9605156A patent/MX9605156A/es unknown
- 1996-10-25 AR ARP960104906A patent/AR004694A1/es unknown
- 1996-10-25 BR BR9605267A patent/BR9605267A/pt not_active Application Discontinuation
-
1999
- 1999-02-03 US US09/243,822 patent/US6551999B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE230275T1 (de) | 2003-01-15 |
HUP9602943A3 (en) | 1998-03-02 |
HUP9602943A2 (en) | 1997-08-28 |
DE69625622D1 (de) | 2003-02-06 |
AR004694A1 (es) | 1999-03-10 |
CA2188817C (en) | 2010-01-26 |
CA2188817A1 (en) | 1997-04-26 |
US6057290A (en) | 2000-05-02 |
AU7038496A (en) | 1997-05-01 |
EP0771565A3 (de) | 1998-11-04 |
ES2193615T3 (es) | 2003-11-01 |
AU716495B2 (en) | 2000-02-24 |
EP0771565B1 (de) | 2003-01-02 |
DE69625575T2 (de) | 2003-09-25 |
EP0927716B1 (de) | 2003-05-07 |
BR9605267A (pt) | 1998-07-21 |
EP0771565A2 (de) | 1997-05-07 |
DE69628050D1 (de) | 2003-06-12 |
DE69628050T2 (de) | 2004-04-01 |
DE69625575D1 (de) | 2003-02-06 |
NO964514D0 (no) | 1996-10-24 |
US6551999B1 (en) | 2003-04-22 |
PL316669A1 (en) | 1997-04-28 |
DE69625622T2 (de) | 2003-08-14 |
EP0927716A1 (de) | 1999-07-07 |
ATE239698T1 (de) | 2003-05-15 |
ES2190139T3 (es) | 2003-07-16 |
MX9605156A (es) | 1998-05-31 |
NO964514L (no) | 1997-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |