KR20100023833A - 식물 배지에서 만노스 풍부 단백질의 제조 - Google Patents

식물 배지에서 만노스 풍부 단백질의 제조 Download PDF

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KR20100023833A
KR20100023833A KR1020097024840A KR20097024840A KR20100023833A KR 20100023833 A KR20100023833 A KR 20100023833A KR 1020097024840 A KR1020097024840 A KR 1020097024840A KR 20097024840 A KR20097024840 A KR 20097024840A KR 20100023833 A KR20100023833 A KR 20100023833A
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South Korea
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lysosomal protein
human
cells
protein
leu
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요셉 샤알티엘
기데온 바움
다니엘 발트펠드
샤론 하쉬무엘리
아얄라 레코위츠
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프로탈릭스 리미티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
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    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
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    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
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    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01022—Alpha-galactosidase (3.2.1.22)
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01045—Glucosylceramidase (3.2.1.45), i.e. beta-glucocerebrosidase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif

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KR1020097024840A 2007-04-30 2008-04-30 식물 배지에서 만노스 풍부 단백질의 제조 Withdrawn KR20100023833A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/790,991 US7951557B2 (en) 2003-04-27 2007-04-30 Human lysosomal proteins from plant cell culture
US11/790,991 2007-04-30

Publications (1)

Publication Number Publication Date
KR20100023833A true KR20100023833A (ko) 2010-03-04

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KR1020097024840A Withdrawn KR20100023833A (ko) 2007-04-30 2008-04-30 식물 배지에서 만노스 풍부 단백질의 제조

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Country Link
US (8) US7951557B2 (https=)
EP (1) EP2220105A4 (https=)
JP (1) JP2010525806A (https=)
KR (1) KR20100023833A (https=)
CN (1) CN101855232A (https=)
AU (1) AU2008243744A1 (https=)
BR (1) BRPI0810003A2 (https=)
CA (1) CA2685400A1 (https=)
MX (1) MX2009011751A (https=)
RU (1) RU2009143751A (https=)
WO (1) WO2008132743A2 (https=)
ZA (1) ZA200908423B (https=)

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US20110182868A1 (en) 2011-07-28
US20110250181A1 (en) 2011-10-13
CN101855232A (zh) 2010-10-06
WO2008132743A2 (en) 2008-11-06
US8449876B2 (en) 2013-05-28
BRPI0810003A2 (pt) 2015-07-21
US20140271577A1 (en) 2014-09-18
US8790641B2 (en) 2014-07-29
JP2010525806A (ja) 2010-07-29
US7951557B2 (en) 2011-05-31
US20130177538A1 (en) 2013-07-11
US8741620B2 (en) 2014-06-03
WO2008132743A3 (en) 2010-06-03
US9220737B2 (en) 2015-12-29
ZA200908423B (en) 2010-12-29
EP2220105A2 (en) 2010-08-25
MX2009011751A (es) 2010-02-22
US8227230B2 (en) 2012-07-24
US20120282231A1 (en) 2012-11-08
US20090208477A1 (en) 2009-08-20
US20080038232A1 (en) 2008-02-14
AU2008243744A1 (en) 2008-11-06
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