KR20080019014A - 키토산 및 사이클로덱스트린을 포함하는 나노입자 - Google Patents

키토산 및 사이클로덱스트린을 포함하는 나노입자 Download PDF

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Publication number
KR20080019014A
KR20080019014A KR1020077029819A KR20077029819A KR20080019014A KR 20080019014 A KR20080019014 A KR 20080019014A KR 1020077029819 A KR1020077029819 A KR 1020077029819A KR 20077029819 A KR20077029819 A KR 20077029819A KR 20080019014 A KR20080019014 A KR 20080019014A
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KR
South Korea
Prior art keywords
cyclodextrin
chitosan
nanoparticles
biologically active
active molecule
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Ceased
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KR1020077029819A
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English (en)
Korean (ko)
Inventor
엠에이 호세 알론소 페르난데스
마르코스 가르시아 푸엔테스
프란세스카 마에스트렐리
파올라 무라
Original Assignee
유니버시다데 데 산티아고 데 콤포스텔라
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Application filed by 유니버시다데 데 산티아고 데 콤포스텔라 filed Critical 유니버시다데 데 산티아고 데 콤포스텔라
Publication of KR20080019014A publication Critical patent/KR20080019014A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5161Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020077029819A 2005-06-02 2006-06-01 키토산 및 사이클로덱스트린을 포함하는 나노입자 Ceased KR20080019014A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ESP200501331 2005-06-02
ES200501331A ES2277743B2 (es) 2005-06-02 2005-06-02 Nanoparticulas que comprenden quitosano y ciclodextrina.

Publications (1)

Publication Number Publication Date
KR20080019014A true KR20080019014A (ko) 2008-02-29

Family

ID=37482018

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077029819A Ceased KR20080019014A (ko) 2005-06-02 2006-06-01 키토산 및 사이클로덱스트린을 포함하는 나노입자

Country Status (11)

Country Link
US (1) US20080220030A1 (https=)
EP (1) EP1891943A2 (https=)
JP (1) JP5191884B2 (https=)
KR (1) KR20080019014A (https=)
CN (1) CN101217947B (https=)
AU (1) AU2006254128A1 (https=)
BR (1) BRPI0613234A2 (https=)
CA (1) CA2610403A1 (https=)
ES (1) ES2277743B2 (https=)
IL (1) IL187696A0 (https=)
WO (1) WO2006128937A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102034982B1 (ko) * 2019-03-08 2019-10-21 주식회사 제론바이오 Pdrn이 캡슐화된 키토산 나노 입자가 포함된 점안제 및 이의 제조 방법
KR102172667B1 (ko) * 2020-02-05 2020-11-02 이채현 덱스트린 글루코노 락톤 술폰 유도체의 제조 방법 및 약제학적 조성물 이를 이용한 동물, 인간, 어류 등의 바이러스 질환 예방 및 치료제

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ES2310122B1 (es) * 2007-04-20 2009-10-30 Instituto Cientifico Y Tecnologico De Navarra, S.A Nanoparticulas que comprenden una ciclodextrina y una molecula biologicamente activa y sus aplicaciones.
US20110064664A1 (en) * 2007-10-08 2011-03-17 The Board Of Regents Of The University Of Texas System Methods and compositions involving chitosan nanoparticles
UA90013C2 (ru) * 2008-03-19 2010-03-25 Давид Анатолійович Нога Фармацевтическая композиция, содержащая инсулин, и способ его получения
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JP5841044B2 (ja) * 2009-03-23 2016-01-06 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. 複合糖質ワクチン
JP5804453B2 (ja) * 2009-05-14 2015-11-04 国立大学法人 東京大学 結晶性ポリオール微粒子及びその調製方法
CN102481360B (zh) * 2009-06-25 2015-06-17 生物领先公司 包含聚γ谷氨酸-壳聚糖纳米颗粒的佐剂组合物
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CN102416000B (zh) * 2011-12-13 2013-04-10 张维芬 一种用于肺吸入的壳聚糖季铵盐大孔微球及其制备方法
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JP2016510001A (ja) * 2013-02-21 2016-04-04 マサチューセッツ インスティテュート オブ テクノロジー シスプラチン充填キトサンナノ粒子を含む標的化された頬側送達
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CN110522921A (zh) * 2018-05-24 2019-12-03 广东省医疗器械研究所 一种具有胰岛素捕获功能的胰岛素输运体系的合成方法
CN108849995B (zh) * 2018-06-12 2020-06-30 甘肃省科学院生物研究所 黄帚橐吾提取物纳米杀虫剂及其制备方法
CN109012629B (zh) * 2018-08-16 2021-07-30 南京大学 一种制备磁性羧甲基β-环糊精聚合物的方法及其应用
CN109908367A (zh) * 2019-04-30 2019-06-21 南开大学 磺胺酸-β-环糊精介导的超分子纳米粒子在胰岛素的控制释放方面的应用
CN110384684B (zh) * 2019-08-26 2021-04-06 安徽农业大学 一种单羧基壳聚糖/紫草素复合纳米颗粒及其制备方法
KR102904096B1 (ko) * 2019-12-06 2025-12-24 (주) 에이치엔에이파마켐 공유결합성 유기 골격체 및 폴리머를 이용한 경피전달용 복합체
JP7319931B2 (ja) * 2020-01-22 2023-08-02 オリエンタル酵母工業株式会社 キトサン部分分解物の安定化方法、キトサン部分分解物の保存方法および食品用保存剤
CN111437381B (zh) * 2020-02-13 2023-12-12 汕头大学 一种水凝胶微粒及其制备方法
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KR102034982B1 (ko) * 2019-03-08 2019-10-21 주식회사 제론바이오 Pdrn이 캡슐화된 키토산 나노 입자가 포함된 점안제 및 이의 제조 방법
WO2020184916A1 (ko) * 2019-03-08 2020-09-17 주식회사 제론바이오 Pdrn이 캡슐화된 키토산 나노 입자가 포함된 점안제 및 이의 제조 방법
US12427107B2 (en) 2019-03-08 2025-09-30 Zerone Bio Inc. Eye drops containing chitosan nanoparticles in which PDRN is encapsulated, and preparation method therefor
KR102172667B1 (ko) * 2020-02-05 2020-11-02 이채현 덱스트린 글루코노 락톤 술폰 유도체의 제조 방법 및 약제학적 조성물 이를 이용한 동물, 인간, 어류 등의 바이러스 질환 예방 및 치료제

Also Published As

Publication number Publication date
CN101217947A (zh) 2008-07-09
ES2277743B2 (es) 2008-12-16
ES2277743A1 (es) 2007-07-16
AU2006254128A1 (en) 2006-12-07
EP1891943A2 (en) 2008-02-27
WO2006128937A3 (es) 2007-02-15
JP2008542342A (ja) 2008-11-27
JP5191884B2 (ja) 2013-05-08
CA2610403A1 (en) 2006-12-07
US20080220030A1 (en) 2008-09-11
CN101217947B (zh) 2012-04-25
WO2006128937A2 (es) 2006-12-07
BRPI0613234A2 (pt) 2010-12-28
IL187696A0 (en) 2008-08-07

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