KR20070065870A - 다량의 숙신산염을 생산하는 세균 - Google Patents

다량의 숙신산염을 생산하는 세균 Download PDF

Info

Publication number
KR20070065870A
KR20070065870A KR1020077004124A KR20077004124A KR20070065870A KR 20070065870 A KR20070065870 A KR 20070065870A KR 1020077004124 A KR1020077004124 A KR 1020077004124A KR 20077004124 A KR20077004124 A KR 20077004124A KR 20070065870 A KR20070065870 A KR 20070065870A
Authority
KR
South Korea
Prior art keywords
pta
succinate
poxb
dehydrogenase
iclr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020077004124A
Other languages
English (en)
Korean (ko)
Inventor
카-위우 산
조오지 엔. 베네트
헨리 린
아일렌 산체스
Original Assignee
라이스 유니버시티
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 라이스 유니버시티 filed Critical 라이스 유니버시티
Publication of KR20070065870A publication Critical patent/KR20070065870A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020077004124A 2004-09-17 2005-09-16 다량의 숙신산염을 생산하는 세균 Withdrawn KR20070065870A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61075004P 2004-09-17 2004-09-17
US60/610,750 2004-09-17

Publications (1)

Publication Number Publication Date
KR20070065870A true KR20070065870A (ko) 2007-06-25

Family

ID=36090558

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077004124A Withdrawn KR20070065870A (ko) 2004-09-17 2005-09-16 다량의 숙신산염을 생산하는 세균

Country Status (7)

Country Link
US (1) US20060073577A1 (cg-RX-API-DMAC7.html)
EP (1) EP1789569A2 (cg-RX-API-DMAC7.html)
JP (1) JP2008513023A (cg-RX-API-DMAC7.html)
KR (1) KR20070065870A (cg-RX-API-DMAC7.html)
CN (1) CN101023178A (cg-RX-API-DMAC7.html)
BR (1) BRPI0515273A (cg-RX-API-DMAC7.html)
WO (1) WO2006034156A2 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12600991B2 (en) 2019-04-12 2026-04-14 Green Earth Institute Co., Ltd. Genetically modified microorganism for production of aspartic acid and downstream metabolites from aspartic acid as target substance, and method for producing target substance using same

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4469568B2 (ja) 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
US7927859B2 (en) * 2003-08-22 2011-04-19 Rice University High molar succinate yield bacteria by increasing the intracellular NADH availability
US7244610B2 (en) * 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
KR101245428B1 (ko) * 2004-08-27 2013-03-19 라이스 유니버시티 숙신산 생산이 증가된 돌연변이 대장균 균주
WO2006069174A2 (en) * 2004-12-22 2006-06-29 Rice University Simultaneous anaerobic production of isoamyl acetate and succinic acid
CN101300356A (zh) * 2005-09-09 2008-11-05 基因组股份公司 用于琥珀酸盐之生长关联性生产的方法和生物
US7335066B2 (en) * 2005-12-16 2008-02-26 James A. Carroll Network connector and connection system
CN101389752B (zh) * 2006-02-24 2015-08-05 三菱化学株式会社 能够产生有机酸的细菌以及产生有机酸的方法
KR101390085B1 (ko) * 2006-03-31 2014-04-28 라이스 유니버시티 글리세롤의 혐기성 발효
KR100780324B1 (ko) * 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
EP2084288A1 (en) * 2006-10-31 2009-08-05 Metabolic Explorer Process for the biological production of 1,3-propanediol from glycerol with high yield
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
US8673601B2 (en) * 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
DE102007019184A1 (de) 2007-04-20 2008-10-23 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
US8026386B2 (en) * 2007-08-10 2011-09-27 Genomatica, Inc. Methods for the synthesis of olefins and derivatives
US7947483B2 (en) * 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
KR101575912B1 (ko) 2007-08-17 2015-12-08 바스프 에스이 파스테우렐라세애의 카복실산 생산 구성원
WO2009072562A1 (ja) 2007-12-06 2009-06-11 Ajinomoto Co., Inc. 有機酸の製造方法
EP2225373A4 (en) * 2007-12-13 2014-04-30 Glycos Biotechnologies Inc MICROBIAL CONVERSION OF OILS AND FATTY ACIDS IN HIGH-VALUE CHEMICALS
CA2712779C (en) 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
DK2262901T3 (en) 2008-03-05 2019-01-21 Genomatica Inc ORGANISMS PRODUCING PRIMARY ALCOHOL
ES2656790T3 (es) 2008-03-27 2018-02-28 Genomatica, Inc. Microorganismos para la producción de ácido adípico y otros compuestos
WO2009135074A2 (en) 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
BRPI0913901A2 (pt) * 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
WO2010006076A2 (en) * 2008-07-08 2010-01-14 Opx Biotechnologies Inc. Methods, compositions and systems for biosynthetic bio production of 1,4-butanediol
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
KR101613754B1 (ko) 2008-10-03 2016-04-19 메타볼릭 익스플로러 강하 막, 와이프드 막, 박막 또는 단경로 증발기를 사용한 발효 브로쓰로부터의 알콜의 정제 방법
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
EP2373781A4 (en) * 2008-12-16 2012-10-10 Genomatica Inc MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS
ES2559385T3 (es) 2008-12-23 2016-02-11 Basf Se Células bacterianas que tienen una derivación de glioxilato para la fabricación de ácido succínico
EP2204443B1 (en) 2008-12-23 2015-11-25 Basf Se Bacterial cells exhibiting formate dehydrogenase activity for the manufacture of suc-cinic acid
FR2941959B1 (fr) * 2009-02-12 2013-06-07 Roquette Freres Procedes de production d'acide succinique
EP2396401B1 (en) * 2009-02-16 2018-12-19 Basf Se Novel microbial succinic acid producers and purification of succinic acid
EP2233562A1 (en) 2009-03-24 2010-09-29 Metabolic Explorer Method for producing high amount of glycolic acid by fermentation
CA2756705C (en) * 2009-04-02 2017-04-11 University Of Florida Research Foundation, Inc. Engineered bacterial cells for succinate production
BRPI1013505A2 (pt) 2009-04-30 2018-02-14 Genomatica Inc organismos para a produção de isopropanol, n-butanol, e isobutanol
MY176050A (en) 2009-04-30 2020-07-22 Genomatica Inc Organisms for the production of 1,3-butanediol
EP2427544B1 (en) 2009-05-07 2019-07-17 Genomatica, Inc. Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid
JP2012526561A (ja) * 2009-05-15 2012-11-01 ゲノマチカ， インク． シクロヘキサノンの産生のための生物
WO2010141468A1 (en) * 2009-06-01 2010-12-09 Way Jeffrey C Methods and molecules for yield improvement involving metabolic engineering
CN101613669B (zh) * 2009-06-04 2012-01-25 山东大学 一株用于好氧发酵的大肠杆菌工程菌株
WO2010141920A2 (en) * 2009-06-04 2010-12-09 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
EP2440669A4 (en) * 2009-06-10 2013-08-28 Genomatica Inc MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL
EP3190174A1 (en) 2009-08-05 2017-07-12 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
US8715971B2 (en) 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
KR20120083908A (ko) 2009-10-13 2012-07-26 게노마티카 인코포레이티드 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-ｃｏａ, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
JP2013511277A (ja) 2009-11-18 2013-04-04 ミリアント・コーポレイション 化学物質の効率的な生産のための微生物の改変
US8778656B2 (en) 2009-11-18 2014-07-15 Myriant Corporation Organic acid production in microorganisms by combined reductive and oxidative tricaboxylic acid cylce pathways
KR20120120493A (ko) * 2009-12-10 2012-11-01 게노마티카 인코포레이티드 합성 가스 또는 기타 가스상 탄소원 및 메탄올을 1,3-부탄디올로 변환하는 방법 및 변환용 유기체
WO2011083059A1 (en) * 2010-01-06 2011-07-14 Universiteit Gent Bacterial mutants and uses thereof in protein production
JP2013517796A (ja) 2010-01-29 2013-05-20 ジェノマティカ・インコーポレイテッド ｐ−トルイル酸およびテレフタル酸を生合成するための方法および微生物
US8445244B2 (en) * 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
CN102812127B (zh) 2010-03-09 2014-12-03 三菱化学株式会社 琥珀酸的制造方法
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
CA2797409C (en) 2010-05-05 2019-12-24 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
WO2011163128A1 (en) 2010-06-21 2011-12-29 William Marsh Rice University Engineered bacteria produce succinate from sucrose
PH12013500158A1 (en) 2010-07-26 2013-03-11 Genomatica Inc Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
CA2807102C (en) 2010-07-31 2018-08-21 Myriant Corporation Improved fermentation process for the production of organic acids
CN102286387A (zh) * 2011-06-21 2011-12-21 江南大学 一株产富马酸的光滑球拟酵母工程菌的构建方法及应用
US9169486B2 (en) 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto
CA2850480A1 (en) * 2011-09-30 2013-06-20 Mascoma Corporation Engineering microorganisms to increase ethanol production by metabolic redirection
EP3517631B9 (en) 2011-12-16 2023-10-04 Inbiose N.V. Mutant microorganisms to synthesize ph sensitive molecules and organic acids
CN102618570B (zh) * 2012-03-20 2014-04-09 南京工业大学 构建产富马酸大肠杆菌基因工程菌的方法
MX2015001780A (es) 2012-08-10 2015-09-28 Opx Biotechnologies Inc Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos.
WO2014055670A1 (en) * 2012-10-02 2014-04-10 The Michigan Biotechynology Institute Recombinant microorganisms for producing organic acids
BE1021047B1 (fr) * 2013-01-18 2015-02-25 Man To Tree S.A. Actinobacillus succinogenes genetiquement modifiee et son utilisation pour la production d'acide succinique
CN103981203B (zh) * 2013-02-07 2018-01-12 中国科学院天津工业生物技术研究所 5‑氨基乙酰丙酸高产菌株及其制备方法和应用
US20150119601A1 (en) 2013-03-15 2015-04-30 Opx Biotechnologies, Inc. Monofunctional mcr + 3-hp dehydrogenase
CN104178443B (zh) * 2013-05-24 2017-04-12 中国科学院天津工业生物技术研究所 生产丁二酸的重组大肠杆菌及其应用
CN104178442B (zh) 2013-05-24 2017-10-31 中国科学院天津工业生物技术研究所 含有突变的lpdA基因的大肠杆菌及其应用
EP3022310B1 (en) 2013-07-19 2019-10-16 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
MY180352A (en) * 2014-04-11 2020-11-28 String Bio Private Ltd Recombinant methanotrophic bacterium and a method of production of succinic acid from methane or biogas thereof
DE102015112882B4 (de) * 2014-09-01 2022-06-30 Uniwersytet Wrocławski Methoden zur Regelung der Verlaufsbedingungen für biologische Prozesse, Reaktor zur Umsetzung dieser Methode sowie System zur Regelung der Verlaufsbedingungen von Prozessen in biologischen Reaktoren
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
CN104651289B (zh) * 2015-01-28 2017-09-26 江南大学 一种弱化发酵过程中乙酸积累以增强l‑色氨酸产量的基因工程菌及其构建方法
TWI673360B (zh) 2015-11-12 2019-10-01 財團法人工業技術研究院 促進琥珀酸或乳酸生產的基因改質菌株及方法
US11345938B2 (en) 2017-02-02 2022-05-31 Cargill, Incorporated Genetically modified cells that produce C6-C10 fatty acid derivatives
KR102129379B1 (ko) 2018-10-10 2020-07-02 한국과학기술원 고활성의 말산 탈수소효소가 도입된 숙신산 생성용 변이 미생물 및 이를 이용한 숙신산 제조방법
WO2020132737A2 (en) 2018-12-28 2020-07-02 Braskem S.A. Modulation of carbon flux through the meg and c3 pathways for the improved production of monoethylene glycol and c3 compounds
JPWO2024242124A1 (cg-RX-API-DMAC7.html) * 2023-05-23 2024-11-28

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869301A (en) * 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
KR19990013007A (ko) * 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ｓｓ373(ｋｃｔｃ 8818ｐ)과 이를 이용한숙신산의 생산방법
US20030087381A1 (en) * 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
WO1999053035A1 (en) * 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
US6159738A (en) * 1998-04-28 2000-12-12 University Of Chicago Method for construction of bacterial strains with increased succinic acid production
CA2466133A1 (en) * 2001-11-02 2003-05-15 Rice University Recycling system for manipulation of intracellular nadh availability
WO2004044210A2 (en) * 2002-11-06 2004-05-27 University Of Florida Materials and methods for the efficient production of acetate and other products
JP4275666B2 (ja) * 2003-02-24 2009-06-10 財団法人地球環境産業技術研究機構 微生物による高効率水素製造方法
US20040199941A1 (en) * 2003-03-24 2004-10-07 Rice University Increased bacterial CoA and acetyl-CoA pools
US7927859B2 (en) * 2003-08-22 2011-04-19 Rice University High molar succinate yield bacteria by increasing the intracellular NADH availability
US7244610B2 (en) * 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
US7326557B2 (en) * 2003-11-14 2008-02-05 Rice University Increasing intracellular NADPH availability in E. coli
WO2006020663A2 (en) * 2004-08-09 2006-02-23 Rice University Aerobic succinate production in bacteria
KR101245428B1 (ko) * 2004-08-27 2013-03-19 라이스 유니버시티 숙신산 생산이 증가된 돌연변이 대장균 균주

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12600991B2 (en) 2019-04-12 2026-04-14 Green Earth Institute Co., Ltd. Genetically modified microorganism for production of aspartic acid and downstream metabolites from aspartic acid as target substance, and method for producing target substance using same

Also Published As

Publication number Publication date
BRPI0515273A (pt) 2008-08-05
WO2006034156A3 (en) 2006-08-24
JP2008513023A (ja) 2008-05-01
CN101023178A (zh) 2007-08-22
US20060073577A1 (en) 2006-04-06
WO2006034156A2 (en) 2006-03-30
EP1789569A2 (en) 2007-05-30

Similar Documents

Publication Publication Date Title
KR20070065870A (ko) 다량의 숙신산염을 생산하는 세균
KR101245428B1 (ko) 숙신산 생산이 증가된 돌연변이 대장균 균주
US7262046B2 (en) Aerobic succinate production in bacteria
US7244610B2 (en) Aerobic succinate production in bacteria
AU780135B2 (en) Methods and materials for the synthesis of organic products
EP3006556B1 (en) Recombinant escherichia coli for producing succinic acid and application thereof
US8778656B2 (en) Organic acid production in microorganisms by combined reductive and oxidative tricaboxylic acid cylce pathways
US8486686B2 (en) Large scale microbial culture method
BRPI1008267B1 (pt) Processo para a produção fermentativa de ácido succínico
AU2003287625A8 (en) Materials and methods for the efficient production of acetate and other products
WO2006069174A2 (en) Simultaneous anaerobic production of isoamyl acetate and succinic acid
RU2537003C2 (ru) Мутантный микроорганизм, продуцирующий янтарную кислоту, способ его получения и способ получения янтарной кислоты (варианты).
US20100159542A1 (en) Bacterial cells exhibiting formate dehydrogenase activity for the manufacture of succinic acid
San et al. Mutant E. coli strain with increased succinic acid production

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20070222

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid