KR20010085974A - 신규 ｇ 단백질 공액형 리셉터 단백질, 그 ｄｎａ 및 그에대한 리간드 - Google Patents

신규 ｇ 단백질 공액형 리셉터 단백질, 그 ｄｎａ 및 그에대한 리간드 Download PDF

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Publication number
KR20010085974A
KR20010085974A KR1020017005344A KR20017005344A KR20010085974A KR 20010085974 A KR20010085974 A KR 20010085974A KR 1020017005344 A KR1020017005344 A KR 1020017005344A KR 20017005344 A KR20017005344 A KR 20017005344A KR 20010085974 A KR20010085974 A KR 20010085974A
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KR
South Korea
Prior art keywords
protein
present
receptor protein
ligand
salt
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English (en)
Korean (ko)
Inventor
타쿠야 와타나베
야스코 테라오
야스시 신타니
테츠야 오타키
키미코 카네하시
치에코 키타다
Original Assignee
다케다 야쿠힌 고교 가부시키가이샤
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Publication of KR20010085974A publication Critical patent/KR20010085974A/ko
Withdrawn legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
KR1020017005344A 1998-10-27 1999-10-26 신규 ｇ 단백질 공액형 리셉터 단백질, 그 ｄｎａ 및 그에대한 리간드 Withdrawn KR20010085974A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP30594998 1998-10-27
JP1998-305949 1998-10-27
JP1999-27710 1999-02-04
JP2771099 1999-02-04
JP5720799 1999-03-04
JP1999-57207 1999-03-04
JP27622599A JP4486187B2 (ja) 1998-10-27 1999-09-29 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド
JP1999-276225 1999-09-29
PCT/JP1999/005905 WO2000024890A1 (en) 1998-10-27 1999-10-26 Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same

Publications (1)

Publication Number Publication Date
KR20010085974A true KR20010085974A (ko) 2001-09-07

Family

ID=27458743

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017005344A Withdrawn KR20010085974A (ko) 1998-10-27 1999-10-26 신규 ｇ 단백질 공액형 리셉터 단백질, 그 ｄｎａ 및 그에대한 리간드

Country Status (19)

Country Link
US (3) US6699965B1 (enExample)
EP (1) EP1126028B1 (enExample)
JP (1) JP4486187B2 (enExample)
KR (1) KR20010085974A (enExample)
CN (1) CN1324405A (enExample)
AT (1) ATE394485T1 (enExample)
AU (1) AU6230699A (enExample)
BR (1) BR9914835A (enExample)
CA (1) CA2347294A1 (enExample)
CZ (1) CZ20011358A3 (enExample)
DE (1) DE69938666D1 (enExample)
HU (1) HUP0104937A2 (enExample)
ID (1) ID28288A (enExample)
IL (1) IL142428A0 (enExample)
NO (1) NO20012059L (enExample)
NZ (1) NZ510977A (enExample)
PL (1) PL347553A1 (enExample)
SK (1) SK5502001A3 (enExample)
WO (1) WO2000024890A1 (enExample)

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WO2000050563A2 (en) * 1999-02-24 2000-08-31 Merck & Co., Inc. G protein-coupled receptor resembling galanin receptors
AU2001244609A1 (en) * 2000-03-30 2001-10-15 Takeda Chemical Industries Ltd. Novel protein, dna thereof and process for producing the same
EP1168259A3 (en) 2000-06-28 2003-12-17 Hitachi, Ltd. Data management method and system for IC card
JP4762481B2 (ja) * 2000-08-30 2011-08-31 株式会社セルフリーサイエンス 無細胞タンパク質合成用転写鋳型の設計および構築、並びにこれを用いる希釈バッチ方式コムギ胚芽無細胞タンパク質合成法
JP2002109169A (ja) 2000-09-29 2002-04-12 Hitachi Ltd 作業支援方法並びにシステム及び作業支援方法を記録した記録媒体
CA2430934C (en) 2000-12-01 2011-06-21 Takeda Chemical Industries, Ltd. A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
EP1363655A4 (en) * 2000-12-18 2005-04-06 Merck & Co Inc FOR A G-PROTEIN-COUPLED RECEPTOR - GPR 54 - FROM HUMAN AND MOUSE-CODING, ISOLATED NUCLEIC ACID MOLECULES, PROTEINS CODED THEREBY, TRANSFORMED CELLS THEREOF, AND USES THEREOF
WO2002057309A1 (fr) * 2001-01-18 2002-07-25 Takeda Chemical Industries, Ltd. Nouvelle proteine receptrice couplee a la proteine g et adn de cette proteine
WO2002072816A1 (fr) * 2001-02-26 2002-09-19 Takeda Chemical Industries, Ltd. Proteine de recepteur murin de type kiss-1 et adn correspondant
WO2002083735A1 (fr) * 2001-04-06 2002-10-24 Takeda Chemical Industries, Ltd. Nouvelle proteine receptrice et son adn
JP2005536439A (ja) 2001-09-18 2005-12-02 ジェネンテック・インコーポレーテッド 腫瘍の診断及び治療のための組成物と方法
AU2008202007B2 (en) * 2001-09-18 2010-12-16 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
WO2003027149A1 (fr) * 2001-09-19 2003-04-03 Takeda Chemical Industries, Ltd. Anticorps et utilisation de ce dernier
CA2472423A1 (en) * 2002-01-11 2003-07-24 Takeda Chemical Industries, Ltd. Process for producing kiss-1 peptide
EP1578373A4 (en) * 2002-09-11 2007-10-24 Genentech Inc NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF ILLNESSES OF THE IMMUNE SYSTEM
CN1761680A (zh) 2002-12-26 2006-04-19 武田药品工业株式会社 肿瘤迁移抑制素衍生物及其用途
US6800611B2 (en) 2003-01-06 2004-10-05 Takeda Chemical Industries, Ltd. Metastin derivatives and their use
WO2004080479A1 (ja) * 2003-03-12 2004-09-23 Takeda Pharmaceutical Company Limited 性腺機能改善剤
JP4639052B2 (ja) * 2003-03-12 2011-02-23 武田薬品工業株式会社 性腺機能改善剤
EP1464652A1 (en) * 2003-04-02 2004-10-06 Institut National De La Sante Et De La Recherche Medicale (Inserm) GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases
AU2004234399A1 (en) * 2003-04-28 2004-11-11 Wyeth Methods utilising G-protein coupled receptor 54
WO2004101747A2 (en) * 2003-05-07 2004-11-25 The General Hospital Corporation Identification and use of gpr54 and its ligands for reproductive disorders and contraception
WO2005040833A1 (en) * 2003-10-21 2005-05-06 Bayer Healthcare Ag Regulation of human metastin recognising receptors
PE20060371A1 (es) 2004-06-25 2006-06-15 Takeda Pharmaceutical Derivados de metastina en el tratamiento del cancer
US20090099334A1 (en) * 2005-12-22 2009-04-16 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
US8404643B2 (en) * 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
ITMI20061607A1 (it) 2006-08-09 2008-02-10 Maria Vincenza Carriero Peptidi con attivita farmacologica
JO3048B1 (ar) * 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها
EP2277900A4 (en) * 2008-04-24 2011-08-03 Takeda Pharmaceutical METASTINE DERIVATIVE AND ITS USE
SMT201700131T1 (it) 2008-07-30 2017-05-08 Takeda Pharmaceuticals Co Derivato di metastina e suo uso
EP2340047A1 (en) * 2008-09-19 2011-07-06 Nektar Therapeutics Polymer conjugates of kiss1 peptides
EP2898900B1 (en) 2008-09-19 2017-11-15 Nektar Therapeutics Polymer conjugates of ziconotide
US8716228B2 (en) 2009-05-27 2014-05-06 Yeda Research And Development Co. Ltd. GPR54 agonists or antagonists for treatment of diseases presenting behavioral abnormalities
EP2873422A4 (en) 2012-07-10 2015-12-30 Takeda Pharmaceutical PHARMACEUTICAL PREPARATION FOR INJECTION
TWI810193B (zh) 2017-07-05 2023-08-01 大陸商尚華醫藥科技（江西）有限公司 一種Kiss1肽類化合物、其應用及含其的組合物
CN109212217B (zh) * 2018-11-07 2021-09-10 李玉民 基于amy1a蛋白胃癌检测试剂盒及其使用方法

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US5436155A (en) * 1991-12-31 1995-07-25 Arch Development Corporation Isolated DNA encoding a somatostatin receptor
US6114139A (en) 1994-08-11 2000-09-05 Takeda Chemical Industries, Ltd. G-protein coupled receptor protein and a DNA encoding the receptor
AU7399296A (en) 1995-10-11 1997-04-30 Penn State Research Foundation, The A metastasis suppressor gene
US6010877A (en) 1997-01-10 2000-01-04 Smithkline Beecham Corporation cDNA clone HE8CS41 that encodes a novel 7-transmembrane receptor
US5851798A (en) 1997-01-27 1998-12-22 Smithkline Beecham Corporation Nucleic acid encoding human GPR14 receptor
CA2283299A1 (en) 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 human secreted proteins
US6420526B1 (en) * 1997-03-07 2002-07-16 Human Genome Sciences, Inc. 186 human secreted proteins
WO2000050563A2 (en) 1999-02-24 2000-08-31 Merck & Co., Inc. G protein-coupled receptor resembling galanin receptors
US20020077469A1 (en) * 1999-03-10 2002-06-20 Borowsky Beth E. DNA encoding orphan SNORF11 receptor
WO2004080479A1 (ja) * 2003-03-12 2004-09-23 Takeda Pharmaceutical Company Limited 性腺機能改善剤

Also Published As

Publication number Publication date
CA2347294A1 (en) 2000-05-04
ATE394485T1 (de) 2008-05-15
EP1126028B1 (en) 2008-05-07
PL347553A1 (en) 2002-04-08
CN1324405A (zh) 2001-11-28
EP1126028A4 (en) 2002-11-27
WO2000024890A1 (en) 2000-05-04
NO20012059D0 (no) 2001-04-26
US7608409B2 (en) 2009-10-27
BR9914835A (pt) 2002-06-18
HUP0104937A2 (hu) 2002-04-29
ID28288A (id) 2001-05-10
US20040180407A1 (en) 2004-09-16
EP1126028A1 (en) 2001-08-22
IL142428A0 (en) 2002-03-10
JP4486187B2 (ja) 2010-06-23
AU6230699A (en) 2000-05-15
SK5502001A3 (en) 2002-01-07
US6699965B1 (en) 2004-03-02
CZ20011358A3 (cs) 2001-08-15
US7314754B2 (en) 2008-01-01
JP2000312590A (ja) 2000-11-14
NZ510977A (en) 2002-10-25
US20080131976A1 (en) 2008-06-05
NO20012059L (no) 2001-06-26
DE69938666D1 (de) 2008-06-19

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