DE69938666D1 - Neue g protein-gekoppelte rezeptor proteine, dnas davon und liganden für diese - Google Patents
Neue g protein-gekoppelte rezeptor proteine, dnas davon und liganden für dieseInfo
- Publication number
- DE69938666D1 DE69938666D1 DE69938666T DE69938666T DE69938666D1 DE 69938666 D1 DE69938666 D1 DE 69938666D1 DE 69938666 T DE69938666 T DE 69938666T DE 69938666 T DE69938666 T DE 69938666T DE 69938666 D1 DE69938666 D1 DE 69938666D1
- Authority
- DE
- Germany
- Prior art keywords
- present
- protein
- coupled receptor
- ligand
- protein coupled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 title abstract 10
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 title abstract 10
- 239000003446 ligand Substances 0.000 title abstract 10
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 6
- 150000003839 salts Chemical class 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000000556 agonist Substances 0.000 abstract 3
- 102000005962 receptors Human genes 0.000 abstract 3
- 108020003175 receptors Proteins 0.000 abstract 3
- 238000012216 screening Methods 0.000 abstract 3
- 239000005557 antagonist Substances 0.000 abstract 2
- 210000004556 brain Anatomy 0.000 abstract 2
- 210000001638 cerebellum Anatomy 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 238000011002 quantification Methods 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30594998 | 1998-10-27 | ||
| JP2771099 | 1999-02-04 | ||
| JP5720799 | 1999-03-04 | ||
| JP27622599A JP4486187B2 (ja) | 1998-10-27 | 1999-09-29 | 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド |
| PCT/JP1999/005905 WO2000024890A1 (en) | 1998-10-27 | 1999-10-26 | Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69938666D1 true DE69938666D1 (de) | 2008-06-19 |
Family
ID=27458743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69938666T Expired - Lifetime DE69938666D1 (de) | 1998-10-27 | 1999-10-26 | Neue g protein-gekoppelte rezeptor proteine, dnas davon und liganden für diese |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US6699965B1 (enExample) |
| EP (1) | EP1126028B1 (enExample) |
| JP (1) | JP4486187B2 (enExample) |
| KR (1) | KR20010085974A (enExample) |
| CN (1) | CN1324405A (enExample) |
| AT (1) | ATE394485T1 (enExample) |
| AU (1) | AU6230699A (enExample) |
| BR (1) | BR9914835A (enExample) |
| CA (1) | CA2347294A1 (enExample) |
| CZ (1) | CZ20011358A3 (enExample) |
| DE (1) | DE69938666D1 (enExample) |
| HU (1) | HUP0104937A2 (enExample) |
| ID (1) | ID28288A (enExample) |
| IL (1) | IL142428A0 (enExample) |
| NO (1) | NO20012059L (enExample) |
| NZ (1) | NZ510977A (enExample) |
| PL (1) | PL347553A1 (enExample) |
| SK (1) | SK5502001A3 (enExample) |
| WO (1) | WO2000024890A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002536989A (ja) * | 1999-02-24 | 2002-11-05 | メルク エンド カムパニー インコーポレーテッド | ガラニン受容体と類似したｇタンパク質共役受容体 |
| WO2001075104A1 (fr) * | 2000-03-30 | 2001-10-11 | Takeda Chemical Industries, Ltd. | Nouvelle proteine, adn codant pour celle-ci, et son procede de production |
| EP1168259A3 (en) | 2000-06-28 | 2003-12-17 | Hitachi, Ltd. | Data management method and system for IC card |
| AU8020201A (en) * | 2000-08-30 | 2002-03-13 | Wakenyaku Co Ltd | Design and construction of transcription template for synthesizing cell-free protein, and dilution batch-type method of synthesizing cell-free wheat germ protein by using the same |
| JP2002109169A (ja) | 2000-09-29 | 2002-04-12 | Hitachi Ltd | 作業支援方法並びにシステム及び作業支援方法を記録した記録媒体 |
| WO2002043709A1 (fr) | 2000-12-01 | 2002-06-06 | Takeda Chemical Industries, Ltd. | Procede de production d'une preparation contenant une substance bioactive |
| US20050075494A1 (en) * | 2000-12-18 | 2005-04-07 | Liu Qingyun | Isolated nucleic acid molecules encoding a human and mouse g protein-coupled receptor-gpr54: encoded proteins, cells transformed therewith and uses thereof |
| WO2002057309A1 (fr) * | 2001-01-18 | 2002-07-25 | Takeda Chemical Industries, Ltd. | Nouvelle proteine receptrice couplee a la proteine g et adn de cette proteine |
| WO2002072816A1 (fr) * | 2001-02-26 | 2002-09-19 | Takeda Chemical Industries, Ltd. | Proteine de recepteur murin de type kiss-1 et adn correspondant |
| WO2002083735A1 (fr) * | 2001-04-06 | 2002-10-24 | Takeda Chemical Industries, Ltd. | Nouvelle proteine receptrice et son adn |
| AU2008202004A1 (en) * | 2001-09-18 | 2008-05-29 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| NZ573739A (en) | 2001-09-18 | 2010-07-30 | Genentech Inc | Compositions and methods for the diagnosis and treatment of tumor, particularly colorectal tumor - TAT201 |
| DE60219645T2 (de) | 2001-09-19 | 2007-08-09 | Takeda Pharmaceutical Co. Ltd. | Antikörper gegen metastin und dessen verwendung zur diagnose von schwangerschaft |
| AU2003201854A1 (en) * | 2002-01-11 | 2003-07-30 | Takeda Chemical Industries, Ltd. | PROCESS FOR PRODUCING KiSS-1 PEPTIDE |
| JP2006521082A (ja) * | 2002-09-11 | 2006-09-21 | ジェネンテック・インコーポレーテッド | 免疫関連疾患の治療のための新規組成物と方法 |
| WO2004063221A1 (ja) | 2002-12-26 | 2004-07-29 | Takeda Pharmaceutical Company Limited | メタスチン誘導体およびその用途 |
| US6800611B2 (en) * | 2003-01-06 | 2004-10-05 | Takeda Chemical Industries, Ltd. | Metastin derivatives and their use |
| JP4639052B2 (ja) * | 2003-03-12 | 2011-02-23 | 武田薬品工業株式会社 | 性腺機能改善剤 |
| US7754220B2 (en) | 2003-03-12 | 2010-07-13 | Takeda Pharmaceutical Company Limited | Methods of inhibiting secretion of follicle-stimulating hormone and testosterone |
| EP1464652A1 (en) * | 2003-04-02 | 2004-10-06 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases |
| US20050026224A1 (en) * | 2003-04-28 | 2005-02-03 | Follettie Maximillian T. | Methods and compositions for modulating G-protein coupled receptor 54 |
| WO2004101747A2 (en) * | 2003-05-07 | 2004-11-25 | The General Hospital Corporation | Identification and use of gpr54 and its ligands for reproductive disorders and contraception |
| WO2005040833A1 (en) * | 2003-10-21 | 2005-05-06 | Bayer Healthcare Ag | Regulation of human metastin recognising receptors |
| WO2006001499A2 (en) | 2004-06-25 | 2006-01-05 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| US8404643B2 (en) * | 2005-12-22 | 2013-03-26 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| AR058584A1 (es) | 2005-12-22 | 2008-02-13 | Takeda Pharmaceutical | Derivados de metastina y uso de los mismos |
| US20090099334A1 (en) * | 2005-12-22 | 2009-04-16 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| ITMI20061607A1 (it) | 2006-08-09 | 2008-02-10 | Maria Vincenza Carriero | Peptidi con attivita farmacologica |
| JO3048B1 (ar) | 2006-10-25 | 2016-09-05 | Takeda Pharmaceuticals Co | مشتقات متاستين واستخدامها |
| US20110118172A1 (en) * | 2008-04-24 | 2011-05-19 | Takeda Pharmaceutical Company Limited | Metastin derivative and use thereof |
| WO2010013762A1 (ja) | 2008-07-30 | 2010-02-04 | 武田薬品工業株式会社 | メタスチン誘導体およびその用途 |
| EP2350118B1 (en) * | 2008-09-19 | 2016-03-30 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
| EP2340047A1 (en) * | 2008-09-19 | 2011-07-06 | Nektar Therapeutics | Polymer conjugates of kiss1 peptides |
| US8716228B2 (en) | 2009-05-27 | 2014-05-06 | Yeda Research And Development Co. Ltd. | GPR54 agonists or antagonists for treatment of diseases presenting behavioral abnormalities |
| US20150157619A1 (en) | 2012-07-10 | 2015-06-11 | Takeda Pharmaceutical Company Limited | Pharmaceutical preparation for injection |
| CN116813705A (zh) | 2017-07-05 | 2023-09-29 | 凯惠科技发展(上海)有限公司 | 一种肽类化合物、其应用及含其的组合物 |
| CN109212217B (zh) * | 2018-11-07 | 2021-09-10 | 李玉民 | 基于amy1a蛋白胃癌检测试剂盒及其使用方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5436155A (en) * | 1991-12-31 | 1995-07-25 | Arch Development Corporation | Isolated DNA encoding a somatostatin receptor |
| US6114139A (en) | 1994-08-11 | 2000-09-05 | Takeda Chemical Industries, Ltd. | G-protein coupled receptor protein and a DNA encoding the receptor |
| WO1997013778A1 (en) | 1995-10-11 | 1997-04-17 | The Penn State Research Foundation | A metastasis suppressor gene |
| US6010877A (en) | 1997-01-10 | 2000-01-04 | Smithkline Beecham Corporation | cDNA clone HE8CS41 that encodes a novel 7-transmembrane receptor |
| US5851798A (en) | 1997-01-27 | 1998-12-22 | Smithkline Beecham Corporation | Nucleic acid encoding human GPR14 receptor |
| CA2283299A1 (en) | 1997-03-07 | 1998-09-11 | Human Genome Sciences, Inc. | 186 human secreted proteins |
| US6420526B1 (en) * | 1997-03-07 | 2002-07-16 | Human Genome Sciences, Inc. | 186 human secreted proteins |
| JP2002536989A (ja) * | 1999-02-24 | 2002-11-05 | メルク エンド カムパニー インコーポレーテッド | ガラニン受容体と類似したｇタンパク質共役受容体 |
| US20020077469A1 (en) * | 1999-03-10 | 2002-06-20 | Borowsky Beth E. | DNA encoding orphan SNORF11 receptor |
| US7754220B2 (en) * | 2003-03-12 | 2010-07-13 | Takeda Pharmaceutical Company Limited | Methods of inhibiting secretion of follicle-stimulating hormone and testosterone |
-
1999
- 1999-09-29 JP JP27622599A patent/JP4486187B2/ja not_active Expired - Fee Related
- 1999-10-26 CA CA002347294A patent/CA2347294A1/en not_active Abandoned
- 1999-10-26 AT AT99949421T patent/ATE394485T1/de not_active IP Right Cessation
- 1999-10-26 CZ CZ20011358A patent/CZ20011358A3/cs unknown
- 1999-10-26 NZ NZ510977A patent/NZ510977A/xx unknown
- 1999-10-26 PL PL99347553A patent/PL347553A1/xx not_active Application Discontinuation
- 1999-10-26 IL IL14242899A patent/IL142428A0/xx unknown
- 1999-10-26 WO PCT/JP1999/005905 patent/WO2000024890A1/ja not_active Ceased
- 1999-10-26 AU AU62306/99A patent/AU6230699A/en not_active Abandoned
- 1999-10-26 CN CN99812722A patent/CN1324405A/zh active Pending
- 1999-10-26 US US09/830,428 patent/US6699965B1/en not_active Expired - Fee Related
- 1999-10-26 BR BR9914835-8A patent/BR9914835A/pt not_active IP Right Cessation
- 1999-10-26 EP EP99949421A patent/EP1126028B1/en not_active Expired - Lifetime
- 1999-10-26 HU HU0104937A patent/HUP0104937A2/hu unknown
- 1999-10-26 KR KR1020017005344A patent/KR20010085974A/ko not_active Withdrawn
- 1999-10-26 DE DE69938666T patent/DE69938666D1/de not_active Expired - Lifetime
- 1999-10-26 SK SK550-2001A patent/SK5502001A3/sk unknown
- 1999-10-27 ID IDW20010936A patent/ID28288A/id unknown
-
2001
- 2001-04-26 NO NO20012059A patent/NO20012059L/no not_active Application Discontinuation
-
2004
- 2004-02-05 US US10/771,417 patent/US7314754B2/en not_active Expired - Fee Related
-
2007
- 2007-10-24 US US11/976,414 patent/US7608409B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010085974A (ko) | 2001-09-07 |
| IL142428A0 (en) | 2002-03-10 |
| AU6230699A (en) | 2000-05-15 |
| EP1126028A4 (en) | 2002-11-27 |
| WO2000024890A1 (en) | 2000-05-04 |
| US20080131976A1 (en) | 2008-06-05 |
| ID28288A (id) | 2001-05-10 |
| HUP0104937A2 (hu) | 2002-04-29 |
| US20040180407A1 (en) | 2004-09-16 |
| US7608409B2 (en) | 2009-10-27 |
| US6699965B1 (en) | 2004-03-02 |
| JP2000312590A (ja) | 2000-11-14 |
| SK5502001A3 (en) | 2002-01-07 |
| US7314754B2 (en) | 2008-01-01 |
| EP1126028A1 (en) | 2001-08-22 |
| CA2347294A1 (en) | 2000-05-04 |
| JP4486187B2 (ja) | 2010-06-23 |
| ATE394485T1 (de) | 2008-05-15 |
| BR9914835A (pt) | 2002-06-18 |
| CZ20011358A3 (cs) | 2001-08-15 |
| PL347553A1 (en) | 2002-04-08 |
| NO20012059L (no) | 2001-06-26 |
| NZ510977A (en) | 2002-10-25 |
| EP1126028B1 (en) | 2008-05-07 |
| CN1324405A (zh) | 2001-11-28 |
| NO20012059D0 (no) | 2001-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |