HUP0104937A2 - Új, G-fehérjéhez kapcsolt receptorfehérje, DNS-e és ligandja - Google Patents

Új, G-fehérjéhez kapcsolt receptorfehérje, DNS-e és ligandja

Info

Publication number
HUP0104937A2
HUP0104937A2 HU0104937A HUP0104937A HUP0104937A2 HU P0104937 A2 HUP0104937 A2 HU P0104937A2 HU 0104937 A HU0104937 A HU 0104937A HU P0104937 A HUP0104937 A HU P0104937A HU P0104937 A2 HUP0104937 A2 HU P0104937A2
Authority
HU
Hungary
Prior art keywords
protein
receptor protein
ligand
salts
peptide
Prior art date
Application number
HU0104937A
Other languages
English (en)
Hungarian (hu)
Inventor
Kimiko Kanehashi
Chieko Kitada
Tetsuya Ohtaki
Yasushi Shintani
Yasuko Terao
Takuya Watanabe
Original Assignee
Takeda Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.
Publication of HUP0104937A2 publication Critical patent/HUP0104937A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
HU0104937A 1998-10-27 1999-10-26 Új, G-fehérjéhez kapcsolt receptorfehérje, DNS-e és ligandja HUP0104937A2 (hu)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP30594998 1998-10-27
JP2771099 1999-02-04
JP5720799 1999-03-04
JP27622599A JP4486187B2 (ja) 1998-10-27 1999-09-29 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド
PCT/JP1999/005905 WO2000024890A1 (en) 1998-10-27 1999-10-26 Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same

Publications (1)

Publication Number Publication Date
HUP0104937A2 true HUP0104937A2 (hu) 2002-04-29

Family

ID=27458743

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104937A HUP0104937A2 (hu) 1998-10-27 1999-10-26 Új, G-fehérjéhez kapcsolt receptorfehérje, DNS-e és ligandja

Country Status (19)

Country Link
US (3) US6699965B1 (enExample)
EP (1) EP1126028B1 (enExample)
JP (1) JP4486187B2 (enExample)
KR (1) KR20010085974A (enExample)
CN (1) CN1324405A (enExample)
AT (1) ATE394485T1 (enExample)
AU (1) AU6230699A (enExample)
BR (1) BR9914835A (enExample)
CA (1) CA2347294A1 (enExample)
CZ (1) CZ20011358A3 (enExample)
DE (1) DE69938666D1 (enExample)
HU (1) HUP0104937A2 (enExample)
ID (1) ID28288A (enExample)
IL (1) IL142428A0 (enExample)
NO (1) NO20012059L (enExample)
NZ (1) NZ510977A (enExample)
PL (1) PL347553A1 (enExample)
SK (1) SK5502001A3 (enExample)
WO (1) WO2000024890A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002536989A (ja) * 1999-02-24 2002-11-05 メルク エンド カムパニー インコーポレーテッド ガラニン受容体と類似したｇタンパク質共役受容体
WO2001075104A1 (fr) * 2000-03-30 2001-10-11 Takeda Chemical Industries, Ltd. Nouvelle proteine, adn codant pour celle-ci, et son procede de production
EP1168259A3 (en) 2000-06-28 2003-12-17 Hitachi, Ltd. Data management method and system for IC card
AU8020201A (en) * 2000-08-30 2002-03-13 Wakenyaku Co Ltd Design and construction of transcription template for synthesizing cell-free protein, and dilution batch-type method of synthesizing cell-free wheat germ protein by using the same
JP2002109169A (ja) 2000-09-29 2002-04-12 Hitachi Ltd 作業支援方法並びにシステム及び作業支援方法を記録した記録媒体
WO2002043709A1 (fr) 2000-12-01 2002-06-06 Takeda Chemical Industries, Ltd. Procede de production d'une preparation contenant une substance bioactive
US20050075494A1 (en) * 2000-12-18 2005-04-07 Liu Qingyun Isolated nucleic acid molecules encoding a human and mouse g protein-coupled receptor-gpr54: encoded proteins, cells transformed therewith and uses thereof
WO2002057309A1 (fr) * 2001-01-18 2002-07-25 Takeda Chemical Industries, Ltd. Nouvelle proteine receptrice couplee a la proteine g et adn de cette proteine
WO2002072816A1 (fr) * 2001-02-26 2002-09-19 Takeda Chemical Industries, Ltd. Proteine de recepteur murin de type kiss-1 et adn correspondant
WO2002083735A1 (fr) * 2001-04-06 2002-10-24 Takeda Chemical Industries, Ltd. Nouvelle proteine receptrice et son adn
AU2008202004A1 (en) * 2001-09-18 2008-05-29 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
NZ573739A (en) 2001-09-18 2010-07-30 Genentech Inc Compositions and methods for the diagnosis and treatment of tumor, particularly colorectal tumor - TAT201
DE60219645T2 (de) 2001-09-19 2007-08-09 Takeda Pharmaceutical Co. Ltd. Antikörper gegen metastin und dessen verwendung zur diagnose von schwangerschaft
AU2003201854A1 (en) * 2002-01-11 2003-07-30 Takeda Chemical Industries, Ltd. PROCESS FOR PRODUCING KiSS-1 PEPTIDE
JP2006521082A (ja) * 2002-09-11 2006-09-21 ジェネンテック・インコーポレーテッド 免疫関連疾患の治療のための新規組成物と方法
WO2004063221A1 (ja) 2002-12-26 2004-07-29 Takeda Pharmaceutical Company Limited メタスチン誘導体およびその用途
US6800611B2 (en) * 2003-01-06 2004-10-05 Takeda Chemical Industries, Ltd. Metastin derivatives and their use
JP4639052B2 (ja) * 2003-03-12 2011-02-23 武田薬品工業株式会社 性腺機能改善剤
US7754220B2 (en) 2003-03-12 2010-07-13 Takeda Pharmaceutical Company Limited Methods of inhibiting secretion of follicle-stimulating hormone and testosterone
EP1464652A1 (en) * 2003-04-02 2004-10-06 Institut National De La Sante Et De La Recherche Medicale (Inserm) GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases
US20050026224A1 (en) * 2003-04-28 2005-02-03 Follettie Maximillian T. Methods and compositions for modulating G-protein coupled receptor 54
WO2004101747A2 (en) * 2003-05-07 2004-11-25 The General Hospital Corporation Identification and use of gpr54 and its ligands for reproductive disorders and contraception
WO2005040833A1 (en) * 2003-10-21 2005-05-06 Bayer Healthcare Ag Regulation of human metastin recognising receptors
WO2006001499A2 (en) 2004-06-25 2006-01-05 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US8404643B2 (en) * 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
US20090099334A1 (en) * 2005-12-22 2009-04-16 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
ITMI20061607A1 (it) 2006-08-09 2008-02-10 Maria Vincenza Carriero Peptidi con attivita farmacologica
JO3048B1 (ar) 2006-10-25 2016-09-05 Takeda Pharmaceuticals Co مشتقات متاستين واستخدامها
US20110118172A1 (en) * 2008-04-24 2011-05-19 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
WO2010013762A1 (ja) 2008-07-30 2010-02-04 武田薬品工業株式会社 メタスチン誘導体およびその用途
EP2350118B1 (en) * 2008-09-19 2016-03-30 Nektar Therapeutics Carbohydrate-based drug delivery polymers and conjugates thereof
EP2340047A1 (en) * 2008-09-19 2011-07-06 Nektar Therapeutics Polymer conjugates of kiss1 peptides
US8716228B2 (en) 2009-05-27 2014-05-06 Yeda Research And Development Co. Ltd. GPR54 agonists or antagonists for treatment of diseases presenting behavioral abnormalities
US20150157619A1 (en) 2012-07-10 2015-06-11 Takeda Pharmaceutical Company Limited Pharmaceutical preparation for injection
CN116813705A (zh) 2017-07-05 2023-09-29 凯惠科技发展(上海)有限公司 一种肽类化合物、其应用及含其的组合物
CN109212217B (zh) * 2018-11-07 2021-09-10 李玉民 基于amy1a蛋白胃癌检测试剂盒及其使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436155A (en) * 1991-12-31 1995-07-25 Arch Development Corporation Isolated DNA encoding a somatostatin receptor
US6114139A (en) 1994-08-11 2000-09-05 Takeda Chemical Industries, Ltd. G-protein coupled receptor protein and a DNA encoding the receptor
WO1997013778A1 (en) 1995-10-11 1997-04-17 The Penn State Research Foundation A metastasis suppressor gene
US6010877A (en) 1997-01-10 2000-01-04 Smithkline Beecham Corporation cDNA clone HE8CS41 that encodes a novel 7-transmembrane receptor
US5851798A (en) 1997-01-27 1998-12-22 Smithkline Beecham Corporation Nucleic acid encoding human GPR14 receptor
CA2283299A1 (en) 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 human secreted proteins
US6420526B1 (en) * 1997-03-07 2002-07-16 Human Genome Sciences, Inc. 186 human secreted proteins
JP2002536989A (ja) * 1999-02-24 2002-11-05 メルク エンド カムパニー インコーポレーテッド ガラニン受容体と類似したｇタンパク質共役受容体
US20020077469A1 (en) * 1999-03-10 2002-06-20 Borowsky Beth E. DNA encoding orphan SNORF11 receptor
US7754220B2 (en) * 2003-03-12 2010-07-13 Takeda Pharmaceutical Company Limited Methods of inhibiting secretion of follicle-stimulating hormone and testosterone

Also Published As

Publication number Publication date
KR20010085974A (ko) 2001-09-07
IL142428A0 (en) 2002-03-10
AU6230699A (en) 2000-05-15
EP1126028A4 (en) 2002-11-27
WO2000024890A1 (en) 2000-05-04
US20080131976A1 (en) 2008-06-05
ID28288A (id) 2001-05-10
US20040180407A1 (en) 2004-09-16
US7608409B2 (en) 2009-10-27
US6699965B1 (en) 2004-03-02
JP2000312590A (ja) 2000-11-14
SK5502001A3 (en) 2002-01-07
US7314754B2 (en) 2008-01-01
EP1126028A1 (en) 2001-08-22
CA2347294A1 (en) 2000-05-04
JP4486187B2 (ja) 2010-06-23
DE69938666D1 (de) 2008-06-19
ATE394485T1 (de) 2008-05-15
BR9914835A (pt) 2002-06-18
CZ20011358A3 (cs) 2001-08-15
PL347553A1 (en) 2002-04-08
NO20012059L (no) 2001-06-26
NZ510977A (en) 2002-10-25
EP1126028B1 (en) 2008-05-07
CN1324405A (zh) 2001-11-28
NO20012059D0 (no) 2001-04-26

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