KR19990062857A - 신경기능 조절제 - Google Patents
신경기능 조절제 Download PDFInfo
- Publication number
- KR19990062857A KR19990062857A KR1019980053416A KR19980053416A KR19990062857A KR 19990062857 A KR19990062857 A KR 19990062857A KR 1019980053416 A KR1019980053416 A KR 1019980053416A KR 19980053416 A KR19980053416 A KR 19980053416A KR 19990062857 A KR19990062857 A KR 19990062857A
- Authority
- KR
- South Korea
- Prior art keywords
- glycosyl
- vitamin
- neurological
- trehalose
- weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dairy Products (AREA)
- Confectionery (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Saccharide Compounds (AREA)
Abstract
Description
판정 | 시료 No. | 대조 | |||
1 2 3 4 | |||||
극히 효과있음 | 3 | 1 | 2 | 0 | 0 |
효과있음 | 5 | 4 | 4 | 4 | 1 |
변화없음 | 2 | 4 | 4 | 5 | 8 |
악화 | 0 | 1 | 0 | 1 | 1 |
효능(%) | 80 | 50 | 60 | 40 | 10 |
Claims (9)
- 글리코실 비타민 P를 유효성분으로 함유하는 신경기능 조절제.
- 제1항에 있어서, 상기 글리코실 비타민 P는 글리코실 헤스페리딘 및/또는 글리코실 루틴인 신경기능 조절제.
- 제1항에 있어서, 상기 글리코실 비타민 P를 0.001w/w% 이상 함유하는 신경기능 조절제.
- 제1항에 있어서, 상기 글리코실 비타민 P 외에 상기 글리코실 비타민 P의 투여를 용이하게 하는 다른 첨가성분을 함유하는 신경기능 조절제.
- 제4항에 있어서, 상기 다른 첨가성분이 식품재료, 식품첨가 성분 및 의약상 허용되는 담체로 된 군으로부터 선택되는 1종인 신경기능 조절제.
- 제1항에 있어서, 트레할로오스를 함유하는 신경기능 조절제.
- 제6항에 있어서, 상기 트레할로오스를 고형물 기준으로 상기 글리코실 비타민 P의 양보다 5배 이상의 양으로 함유하는 신경기능 조절제.
- 제1항에 있어서, 항신경 질환제로서 사용되는 신경기능 조절제.
- 제1항에 있어서, 인간에게 경구투여 또는 비경구 투여되는 신경기능 조절제.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP35406897 | 1997-12-09 | ||
JP97-354068 | 1997-12-09 | ||
JP98-320778 | 1998-11-11 | ||
JP32077898A JP4203159B2 (ja) | 1997-12-09 | 1998-11-11 | 神経機能調節剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR19990062857A true KR19990062857A (ko) | 1999-07-26 |
KR100588953B1 KR100588953B1 (ko) | 2006-10-11 |
Family
ID=26570207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019980053416A KR100588953B1 (ko) | 1997-12-09 | 1998-12-07 | 신경기능조절제 |
Country Status (6)
Country | Link |
---|---|
US (1) | US6232294B1 (ko) |
EP (1) | EP0922460B1 (ko) |
JP (1) | JP4203159B2 (ko) |
KR (1) | KR100588953B1 (ko) |
DE (1) | DE69832250T2 (ko) |
TW (1) | TW443929B (ko) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100776124B1 (ko) * | 2000-09-14 | 2007-11-15 | 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 | 안과용 의약 조성물 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4295840B2 (ja) * | 1997-12-09 | 2009-07-15 | 株式会社林原生物化学研究所 | 血行改善剤 |
DE10315022A1 (de) * | 2003-03-03 | 2004-09-23 | Bioplanta Arzneimittel Gmbh | Verwendung von Rutin und Isorhamnetin zur Behandlung von depressiven Verstimmungen und Erkrankungen sowie bei anderen affektiven Störungen |
WO2004078189A1 (de) * | 2003-03-03 | 2004-09-16 | Bioplanta Arzneimittel Gmbh | Verwendung von rutin und isorhamnetin zur behandlung von depressiven verstimmungen und erkrankungen sowei bei anderen affektiven störungen |
JP3973649B2 (ja) * | 2004-09-03 | 2007-09-12 | 株式会社 伊藤園 | ヘスペリジン含有飲料 |
US20060204601A1 (en) * | 2005-03-09 | 2006-09-14 | Palu Afa K | Formulations and methods for preventing and treating substance abuse and addiction |
EP1721613B1 (de) * | 2005-05-13 | 2007-11-28 | Mewicon med. wiss. Beratung GmbH | Hesperidin zur Behandlung von Epilepsie |
JP5781727B2 (ja) * | 2007-02-23 | 2015-09-24 | 株式会社ネクスト21 | 血管攣縮の治療剤又は予防剤 |
JPWO2010029913A1 (ja) * | 2008-09-11 | 2012-02-02 | 株式会社林原生物化学研究所 | 気力改善剤 |
JP2019043862A (ja) * | 2017-08-30 | 2019-03-22 | キリン株式会社 | 疲労感軽減用または凝り改善用組成物 |
JPWO2020226165A1 (ko) * | 2019-05-08 | 2020-11-12 | ||
JPWO2022255276A1 (ko) * | 2021-06-03 | 2022-12-08 |
Family Cites Families (28)
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PT68117A (fr) | 1977-06-02 | 1978-06-01 | Sarget Lab | Nouveau procede de preparation de derives de glycosides benzopyranniques |
US5145781A (en) | 1989-03-08 | 1992-09-08 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Preparation and uses of alpha-glycosyl rutin |
JP3060227B2 (ja) | 1989-06-03 | 2000-07-10 | 株式会社林原生物化学研究所 | α―グリコシル ヘスペリジンとその製造方法並びに用途 |
IT1232343B (it) * | 1989-09-28 | 1992-01-28 | Eurogefi S P A | Derivati idrosolubili di bioflavonoidi di glicosidici, procedimenti per la loro preparazione e relative composizioni farmaceutiche. |
JP3194145B2 (ja) | 1989-09-28 | 2001-07-30 | 株式会社林原生物化学研究所 | 4G―α―D―グルコピラノシルルチンとその製造方法並びに用途 |
JP2896598B2 (ja) | 1990-10-06 | 1999-05-31 | 株式会社林原生物化学研究所 | ラクトネオトレハロースとその製造方法並びに用途 |
JP3082094B2 (ja) * | 1990-11-15 | 2000-08-28 | 株式会社林原生物化学研究所 | ネオトレハロースの製造方法とその用途 |
US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
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EP0565313B1 (en) | 1992-04-02 | 1997-07-30 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Method to improve taste preference of pine extract, and orally administrable product obtained thereby |
EP0691344B1 (en) | 1992-12-28 | 2003-03-19 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Purification of trehalose |
WO1994018955A1 (en) * | 1993-02-22 | 1994-09-01 | Alza Corporation | Compositions for oral delivery of active agents |
JP3559585B2 (ja) | 1993-06-03 | 2004-09-02 | 株式会社林原生物化学研究所 | トレハロース遊離酵素とその製造方法並びに用途 |
JP3989561B2 (ja) * | 1993-10-13 | 2007-10-10 | 江崎グリコ株式会社 | 可溶性フラボノイド類の製造方法 |
JPH07187974A (ja) * | 1993-12-24 | 1995-07-25 | Lion Corp | 口腔用組成物 |
DE69510116T2 (de) | 1994-02-23 | 1999-11-18 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama | Nicht reduzierendes Saccharid bildendes Enzym, dieses kodierende DNA, und deren Herstellungen und Verwendungen |
DE69532485T2 (de) | 1994-03-07 | 2004-11-04 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung |
JP3557277B2 (ja) | 1994-06-25 | 2004-08-25 | 株式会社林原生物化学研究所 | 耐熱性トレハロース遊離酵素とその製造方法並びに用途 |
AU695080B2 (en) | 1994-06-24 | 1998-08-06 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Thermostable non-reducing saccharide-forming enzyme, its production and uses |
EP0693558B1 (en) | 1994-07-19 | 2002-12-04 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Trehalose and its production and use |
JP3557289B2 (ja) | 1994-07-21 | 2004-08-25 | 株式会社林原生物化学研究所 | 非還元性糖質からトレハロースを遊離する組換え型耐熱性酵素 |
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-
1998
- 1998-11-11 JP JP32077898A patent/JP4203159B2/ja not_active Expired - Lifetime
- 1998-12-02 TW TW087119991A patent/TW443929B/zh not_active IP Right Cessation
- 1998-12-07 US US09/206,692 patent/US6232294B1/en not_active Expired - Lifetime
- 1998-12-07 KR KR1019980053416A patent/KR100588953B1/ko active IP Right Grant
- 1998-12-08 EP EP98310052A patent/EP0922460B1/en not_active Expired - Lifetime
- 1998-12-08 DE DE69832250T patent/DE69832250T2/de not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100776124B1 (ko) * | 2000-09-14 | 2007-11-15 | 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 | 안과용 의약 조성물 |
Also Published As
Publication number | Publication date |
---|---|
US6232294B1 (en) | 2001-05-15 |
DE69832250D1 (de) | 2005-12-15 |
DE69832250T2 (de) | 2006-08-03 |
JP4203159B2 (ja) | 2008-12-24 |
JPH11255655A (ja) | 1999-09-21 |
EP0922460B1 (en) | 2005-11-09 |
EP0922460A1 (en) | 1999-06-16 |
TW443929B (en) | 2001-07-01 |
KR100588953B1 (ko) | 2006-10-11 |
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