KR19990008181A - 알쯔하이머병과 관련된 유전자 서열 및 단백질 및 이의 용도 - Google Patents

알쯔하이머병과 관련된 유전자 서열 및 단백질 및 이의 용도 Download PDF

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Publication number
KR19990008181A
KR19990008181A KR1019970707706A KR19970707706A KR19990008181A KR 19990008181 A KR19990008181 A KR 19990008181A KR 1019970707706 A KR1019970707706 A KR 1019970707706A KR 19970707706 A KR19970707706 A KR 19970707706A KR 19990008181 A KR19990008181 A KR 19990008181A
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South Korea
Prior art keywords
presenilin
protein
seq
sequence
mutant
Prior art date
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Ceased
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KR1019970707706A
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English (en)
Korean (ko)
Inventor
죠지-히슬롭 피터 에이취 세인트
폴 이 프라셔
조한나 엠 롬멘즈
Original Assignee
크리스티안 에이 엠
에이치에스씨 리서치 앤드 디벨롭먼트 리미티드 파트너쉽
문쉐 피터 비
더 거버닝 카운실 오브 더 유니버서티 오브 토론토
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Priority claimed from US08/431,048 external-priority patent/US6531586B1/en
Priority claimed from US08/496,841 external-priority patent/US6210919B1/en
Application filed by 크리스티안 에이 엠, 에이치에스씨 리서치 앤드 디벨롭먼트 리미티드 파트너쉽, 문쉐 피터 비, 더 거버닝 카운실 오브 더 유니버서티 오브 토론토 filed Critical 크리스티안 에이 엠
Publication of KR19990008181A publication Critical patent/KR19990008181A/ko
Ceased legal-status Critical Current

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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KR1019970707706A 1995-04-28 1996-04-29 알쯔하이머병과 관련된 유전자 서열 및 단백질 및 이의 용도 Ceased KR19990008181A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US8/431,048 1995-04-28
US08/431,048 US6531586B1 (en) 1995-04-28 1995-04-28 Genetic sequences related to Alzheimer's Disease
US8/496,841 1995-06-28
US08/496,841 US6210919B1 (en) 1995-04-28 1995-06-28 Genetic sequences and proteins related to alzheimer's disease
US50935995A 1995-07-31 1995-07-31
US8/509,359 1995-07-31

Publications (1)

Publication Number Publication Date
KR19990008181A true KR19990008181A (ko) 1999-01-25

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ID=27411707

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Application Number Title Priority Date Filing Date
KR1019970707706A Ceased KR19990008181A (ko) 1995-04-28 1996-04-29 알쯔하이머병과 관련된 유전자 서열 및 단백질 및 이의 용도

Country Status (19)

Country Link
US (9) US5986054A (enExample)
EP (2) EP2000479A1 (enExample)
JP (3) JP4504463B2 (enExample)
KR (1) KR19990008181A (enExample)
AT (1) ATE405645T1 (enExample)
AU (1) AU716307B2 (enExample)
BR (1) BR9608140A (enExample)
CA (1) CA2219214A1 (enExample)
CZ (1) CZ339097A3 (enExample)
DE (1) DE69637649D1 (enExample)
DK (1) DK0826042T3 (enExample)
ES (1) ES2314979T3 (enExample)
HU (1) HUP9801639A3 (enExample)
MX (1) MX9708270A (enExample)
NO (1) NO974964L (enExample)
NZ (2) NZ335945A (enExample)
PL (1) PL185549B1 (enExample)
SK (1) SK145397A3 (enExample)
WO (1) WO1996034099A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023282552A1 (ko) * 2021-07-08 2023-01-12 주식회사 엠케이바이오텍 Human mutant presenilin-1 발현 인지장애 모델 개의 생산

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5986054A (en) 1995-04-28 1999-11-16 The Hospital For Sick Children, Hsc Research And Development Limited Partnership Genetic sequences and proteins related to alzheimer's disease
JP4073955B2 (ja) * 1995-07-07 2008-04-09 ダーウィン モレキュラー コーポレイション アルツハイマー病に関連する第１染色体の遺伝子および遺伝子産物
JP2000513923A (ja) * 1995-07-18 2000-10-24 ワシントン・ユニバーシティ 変異ｓ１８２遺伝子
WO1997007213A2 (en) * 1995-08-16 1997-02-27 President And Fellows Of Harvard College Assay for identifying genes causing chromosome non-disjunction
US6248555B1 (en) * 1995-08-31 2001-06-19 The General Hospital Corporation Genetic alterations related to familial alzheimer's disease
US6787641B1 (en) * 1995-09-27 2004-09-07 The Trustees Of Columbia University In The City Of New York Identification of sel-12 and uses thereof
ZA968898B (en) * 1995-10-25 1998-03-30 Washington University Of Medic Method for elucidation and detection of polymorphisms, splice variants and proximal coding mutations using intronic sequences of the mutations Alzheimer's S182 gene.
JPH10327897A (ja) * 1996-01-19 1998-12-15 Washington Univ プレセニリン−１遺伝子の配列を用いる疾患の診断および予後診断
JP2000506375A (ja) * 1996-01-26 2000-05-30 エイチエスシー リサーチ アンド デベロップメント リミテッド パートナーシップ アルツハイマー病に関連する核酸およびタンパク質、ならびにその使用
AU2541497A (en) * 1996-04-04 1997-10-29 Institute Of Genomic Research, The Variant presenilin-2 genes
WO1997046678A1 (en) * 1996-06-06 1997-12-11 Bayer Corporation Nucleic acids and polypeptides related to presenilin
EP0811695A3 (en) * 1996-06-06 1998-07-29 Washington University Mutant S182(PS-1) genes
EP0814157A3 (en) * 1996-06-18 1998-01-07 Smithkline Beecham Corporation Diagnostic marker for variants of presenilin genes associated with Alzheimers Disease and Familial Adult Onset Alzheimers Disease
AU3251997A (en) * 1996-07-05 1998-02-02 Governing Council Of The University Of Toronto, The Genetic sequences and proteins related to Alzheimer's disease, and uses herefor
WO1998025142A1 (en) 1996-12-02 1998-06-11 The Brigham And Women's Hospital, Inc. Alarm related peptides and nucleic acids and diagnosis using them
US6376239B1 (en) * 1997-04-04 2002-04-23 Elegene Gmbh DNA molecules comprising a promoter capable of conferring expression of a heterologous DNA sequence
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