KR102713679B1 - 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도 - Google Patents

항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도 Download PDF

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KR102713679B1
KR102713679B1 KR1020237010730A KR20237010730A KR102713679B1 KR 102713679 B1 KR102713679 B1 KR 102713679B1 KR 1020237010730 A KR1020237010730 A KR 1020237010730A KR 20237010730 A KR20237010730 A KR 20237010730A KR 102713679 B1 KR102713679 B1 KR 102713679B1
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antibody
ror2
amino acid
chain variable
variable region
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KR20230044567A (ko
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제이 엠 쇼트
화이 웬 창
게르하르트 프레이
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바이오아트라, 인코퍼레이티드
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    • A—HUMAN NECESSITIES
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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KR1020237010730A 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도 Active KR102713679B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247032268A KR20240148936A (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662335719P 2016-05-13 2016-05-13
US62/335,719 2016-05-13
US201762447218P 2017-01-17 2017-01-17
US62/447,218 2017-01-17
PCT/US2017/032357 WO2017197234A1 (en) 2016-05-13 2017-05-12 Anti-ror2 antibodies, antibody fragments, their immunoconjugates and uses thereof
KR1020187032869A KR20180137517A (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도

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KR1020187032869A Division KR20180137517A (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도

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KR1020247032268A Division KR20240148936A (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도

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KR20230044567A KR20230044567A (ko) 2023-04-04
KR102713679B1 true KR102713679B1 (ko) 2024-10-04

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KR1020237010730A Active KR102713679B1 (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도
KR1020247032268A Pending KR20240148936A (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도
KR1020187032869A Ceased KR20180137517A (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도

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KR1020247032268A Pending KR20240148936A (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도
KR1020187032869A Ceased KR20180137517A (ko) 2016-05-13 2017-05-12 항 ror2 항체, 항체 단편 및 이의 면역접합체와 이것들의 용도

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US (4) US11254742B2 (https=)
EP (2) EP3455261B1 (https=)
JP (4) JP7051715B2 (https=)
KR (3) KR102713679B1 (https=)
CN (3) CN116751298A (https=)
AU (2) AU2017263568B2 (https=)
CA (1) CA3023979A1 (https=)
DK (1) DK3455261T3 (https=)
ES (1) ES2930255T3 (https=)
HR (1) HRP20221298T1 (https=)
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IL (2) IL308504A (https=)
LT (1) LT3455261T (https=)
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PL (1) PL3455261T3 (https=)
PT (1) PT3455261T (https=)
RS (1) RS63698B1 (https=)
SG (1) SG11201808882QA (https=)
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