KR102655833B1 - T-세포 전림프구성 백혈병의 치료에 사용하기 위한 티노스타무스틴 - Google Patents

T-세포 전림프구성 백혈병의 치료에 사용하기 위한 티노스타무스틴 Download PDF

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KR102655833B1
KR102655833B1 KR1020197037098A KR20197037098A KR102655833B1 KR 102655833 B1 KR102655833 B1 KR 102655833B1 KR 1020197037098 A KR1020197037098 A KR 1020197037098A KR 20197037098 A KR20197037098 A KR 20197037098A KR 102655833 B1 KR102655833 B1 KR 102655833B1
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cells
pll
treatment
tinostamustine
pharmaceutically acceptable
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KR20200015563A (ko
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토마스 요르크 메를링
마르코 헤를링
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유로-셀띠끄 소시에떼 아노님
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020197037098A 2017-06-13 2018-06-13 T-세포 전림프구성 백혈병의 치료에 사용하기 위한 티노스타무스틴 Active KR102655833B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1709402.0A GB201709402D0 (en) 2017-06-13 2017-06-13 Compounds for treating t-pll
GB1709402.0 2017-06-13
PCT/EP2018/065664 WO2018229132A1 (en) 2017-06-13 2018-06-13 Tinostamustine for use in the treatment of t-cell prolymphocytic leukaemia

Publications (2)

Publication Number Publication Date
KR20200015563A KR20200015563A (ko) 2020-02-12
KR102655833B1 true KR102655833B1 (ko) 2024-04-08

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KR1020197037098A Active KR102655833B1 (ko) 2017-06-13 2018-06-13 T-세포 전림프구성 백혈병의 치료에 사용하기 위한 티노스타무스틴

Country Status (14)

Country Link
US (4) US11318117B2 (https=)
EP (1) EP3638231B1 (https=)
JP (1) JP7195283B2 (https=)
KR (1) KR102655833B1 (https=)
AR (1) AR112101A1 (https=)
AU (1) AU2018285821B2 (https=)
BR (1) BR112019026484A2 (https=)
CA (1) CA3067276A1 (https=)
ES (1) ES2966954T3 (https=)
GB (1) GB201709402D0 (https=)
IL (1) IL271017A (https=)
MX (1) MX392103B (https=)
TW (1) TW201919616A (https=)
WO (1) WO2018229132A1 (https=)

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GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
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EP4725489A2 (en) 2019-08-02 2026-04-15 OneHealthCompany, Inc. Treatment of canine cancers

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Also Published As

Publication number Publication date
EP3638231B1 (en) 2023-12-20
MX2019015208A (es) 2022-05-03
CA3067276A1 (en) 2018-12-20
GB201709402D0 (en) 2017-07-26
IL271017A (en) 2020-01-30
JP2020523359A (ja) 2020-08-06
KR20200015563A (ko) 2020-02-12
US20240316009A1 (en) 2024-09-26
TW201919616A (zh) 2019-06-01
BR112019026484A2 (pt) 2020-07-14
US20220401417A1 (en) 2022-12-22
WO2018229132A1 (en) 2018-12-20
US20200113871A1 (en) 2020-04-16
AR112101A1 (es) 2019-09-18
EP3638231C0 (en) 2023-12-20
EP3638231A1 (en) 2020-04-22
US11318117B2 (en) 2022-05-03
MX392103B (es) 2025-03-21
ES2966954T3 (es) 2024-04-25
US11918558B2 (en) 2024-03-05
US12370178B2 (en) 2025-07-29
JP7195283B2 (ja) 2022-12-23
US20260083707A1 (en) 2026-03-26
AU2018285821A1 (en) 2019-12-19
AU2018285821B2 (en) 2024-07-04

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