AU2018285821B2 - Tinostamustine for use in the treatment of T-cell prolymphocytic leukaemia - Google Patents

Tinostamustine for use in the treatment of T-cell prolymphocytic leukaemia Download PDF

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Publication number
AU2018285821B2
AU2018285821B2 AU2018285821A AU2018285821A AU2018285821B2 AU 2018285821 B2 AU2018285821 B2 AU 2018285821B2 AU 2018285821 A AU2018285821 A AU 2018285821A AU 2018285821 A AU2018285821 A AU 2018285821A AU 2018285821 B2 AU2018285821 B2 AU 2018285821B2
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AU
Australia
Prior art keywords
pll
tinostamustine
pharmaceutically acceptable
acceptable salt
patient
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AU2018285821A
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AU2018285821A1 (en
Inventor
Marco HERLING
Thomas Jorg MEHRLING
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Euro Celtique SA
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Euro Celtique SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2018285821A 2017-06-13 2018-06-13 Tinostamustine for use in the treatment of T-cell prolymphocytic leukaemia Active AU2018285821B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1709402.0 2017-06-13
GBGB1709402.0A GB201709402D0 (en) 2017-06-13 2017-06-13 Compounds for treating t-pll
PCT/EP2018/065664 WO2018229132A1 (en) 2017-06-13 2018-06-13 Tinostamustine for use in the treatment of t-cell prolymphocytic leukaemia

Publications (2)

Publication Number Publication Date
AU2018285821A1 AU2018285821A1 (en) 2019-12-19
AU2018285821B2 true AU2018285821B2 (en) 2024-07-04

Family

ID=59358363

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018285821A Active AU2018285821B2 (en) 2017-06-13 2018-06-13 Tinostamustine for use in the treatment of T-cell prolymphocytic leukaemia

Country Status (14)

Country Link
US (4) US11318117B2 (https=)
EP (1) EP3638231B1 (https=)
JP (1) JP7195283B2 (https=)
KR (1) KR102655833B1 (https=)
AR (1) AR112101A1 (https=)
AU (1) AU2018285821B2 (https=)
BR (1) BR112019026484A2 (https=)
CA (1) CA3067276A1 (https=)
ES (1) ES2966954T3 (https=)
GB (1) GB201709402D0 (https=)
IL (1) IL271017A (https=)
MX (1) MX392103B (https=)
TW (1) TW201919616A (https=)
WO (1) WO2018229132A1 (https=)

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Also Published As

Publication number Publication date
ES2966954T3 (es) 2024-04-25
US11918558B2 (en) 2024-03-05
KR102655833B1 (ko) 2024-04-08
JP2020523359A (ja) 2020-08-06
JP7195283B2 (ja) 2022-12-23
TW201919616A (zh) 2019-06-01
US11318117B2 (en) 2022-05-03
BR112019026484A2 (pt) 2020-07-14
EP3638231B1 (en) 2023-12-20
US20220401417A1 (en) 2022-12-22
AR112101A1 (es) 2019-09-18
MX392103B (es) 2025-03-21
US12370178B2 (en) 2025-07-29
WO2018229132A1 (en) 2018-12-20
IL271017A (en) 2020-01-30
US20260083707A1 (en) 2026-03-26
US20200113871A1 (en) 2020-04-16
EP3638231A1 (en) 2020-04-22
EP3638231C0 (en) 2023-12-20
US20240316009A1 (en) 2024-09-26
GB201709402D0 (en) 2017-07-26
KR20200015563A (ko) 2020-02-12
MX2019015208A (es) 2022-05-03
CA3067276A1 (en) 2018-12-20
AU2018285821A1 (en) 2019-12-19

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