CA3067276A1 - Tinostamustine for use in the treatment of t-cell prolymphocytic leukaemia - Google Patents

Tinostamustine for use in the treatment of t-cell prolymphocytic leukaemia Download PDF

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Publication number
CA3067276A1
CA3067276A1 CA3067276A CA3067276A CA3067276A1 CA 3067276 A1 CA3067276 A1 CA 3067276A1 CA 3067276 A CA3067276 A CA 3067276A CA 3067276 A CA3067276 A CA 3067276A CA 3067276 A1 CA3067276 A1 CA 3067276A1
Authority
CA
Canada
Prior art keywords
treatment
cells
pll
tinostamustine
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3067276A
Other languages
English (en)
French (fr)
Inventor
Thomas Jorg Mehrling
Marco HERLING
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Publication of CA3067276A1 publication Critical patent/CA3067276A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3067276A 2017-06-13 2018-06-13 Tinostamustine for use in the treatment of t-cell prolymphocytic leukaemia Pending CA3067276A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1709402.0 2017-06-13
GBGB1709402.0A GB201709402D0 (en) 2017-06-13 2017-06-13 Compounds for treating t-pll
PCT/EP2018/065664 WO2018229132A1 (en) 2017-06-13 2018-06-13 Tinostamustine for use in the treatment of t-cell prolymphocytic leukaemia

Publications (1)

Publication Number Publication Date
CA3067276A1 true CA3067276A1 (en) 2018-12-20

Family

ID=59358363

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3067276A Pending CA3067276A1 (en) 2017-06-13 2018-06-13 Tinostamustine for use in the treatment of t-cell prolymphocytic leukaemia

Country Status (14)

Country Link
US (4) US11318117B2 (https=)
EP (1) EP3638231B1 (https=)
JP (1) JP7195283B2 (https=)
KR (1) KR102655833B1 (https=)
AR (1) AR112101A1 (https=)
AU (1) AU2018285821B2 (https=)
BR (1) BR112019026484A2 (https=)
CA (1) CA3067276A1 (https=)
ES (1) ES2966954T3 (https=)
GB (1) GB201709402D0 (https=)
IL (1) IL271017A (https=)
MX (1) MX392103B (https=)
TW (1) TW201919616A (https=)
WO (1) WO2018229132A1 (https=)

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Also Published As

Publication number Publication date
ES2966954T3 (es) 2024-04-25
US11918558B2 (en) 2024-03-05
KR102655833B1 (ko) 2024-04-08
JP2020523359A (ja) 2020-08-06
JP7195283B2 (ja) 2022-12-23
TW201919616A (zh) 2019-06-01
US11318117B2 (en) 2022-05-03
BR112019026484A2 (pt) 2020-07-14
EP3638231B1 (en) 2023-12-20
US20220401417A1 (en) 2022-12-22
AR112101A1 (es) 2019-09-18
MX392103B (es) 2025-03-21
US12370178B2 (en) 2025-07-29
WO2018229132A1 (en) 2018-12-20
IL271017A (en) 2020-01-30
US20260083707A1 (en) 2026-03-26
US20200113871A1 (en) 2020-04-16
EP3638231A1 (en) 2020-04-22
EP3638231C0 (en) 2023-12-20
US20240316009A1 (en) 2024-09-26
AU2018285821B2 (en) 2024-07-04
GB201709402D0 (en) 2017-07-26
KR20200015563A (ko) 2020-02-12
MX2019015208A (es) 2022-05-03
AU2018285821A1 (en) 2019-12-19

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