KR102096937B1 - 비경구 노로바이러스 백신 제제 - Google Patents

비경구 노로바이러스 백신 제제 Download PDF

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KR102096937B1
KR102096937B1 KR1020147003571A KR20147003571A KR102096937B1 KR 102096937 B1 KR102096937 B1 KR 102096937B1 KR 1020147003571 A KR1020147003571 A KR 1020147003571A KR 20147003571 A KR20147003571 A KR 20147003571A KR 102096937 B1 KR102096937 B1 KR 102096937B1
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norovirus
vlp
gene group
vaccine
vaccine composition
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KR20140066160A (ko
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찰스 리처드슨
로버트 에프 바게츠
폴 엠 멘들먼
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다케다 백신즈 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/16011—Caliciviridae
    • C12N2770/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
KR1020147003571A 2011-07-11 2012-07-11 비경구 노로바이러스 백신 제제 Active KR102096937B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161506447P 2011-07-11 2011-07-11
US61/506,447 2011-07-11
PCT/US2012/046222 WO2013009849A1 (en) 2011-07-11 2012-07-11 Parenteral norovirus vaccine formulations

Publications (2)

Publication Number Publication Date
KR20140066160A KR20140066160A (ko) 2014-05-30
KR102096937B1 true KR102096937B1 (ko) 2020-04-03

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US (5) US9801934B2 (enExample)
EP (3) EP2731621B1 (enExample)
JP (2) JP6208659B2 (enExample)
KR (1) KR102096937B1 (enExample)
CN (3) CN105031637A (enExample)
AU (2) AU2012282658B2 (enExample)
BR (1) BR112014000656A2 (enExample)
CA (1) CA2841356C (enExample)
CL (1) CL2014000082A1 (enExample)
CR (2) CR20190540A (enExample)
DK (1) DK3299030T3 (enExample)
DO (2) DOP2014000004A (enExample)
EA (3) EA202090699A3 (enExample)
EC (1) ECSP14013201A (enExample)
ES (2) ES2926487T3 (enExample)
GE (1) GEP201706668B (enExample)
HK (2) HK1199202A1 (enExample)
IL (1) IL230356B (enExample)
MA (1) MA35414B1 (enExample)
MX (2) MX356586B (enExample)
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PH (3) PH12014500093A1 (enExample)
PL (2) PL2731621T3 (enExample)
SG (1) SG10201605644WA (enExample)
TN (1) TN2014000008A1 (enExample)
UA (1) UA117732C2 (enExample)
WO (1) WO2013009849A1 (enExample)
ZA (2) ZA201401012B (enExample)

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CN107184970A (zh) * 2017-02-16 2017-09-22 北京生物制品研究所有限责任公司 口服诺如病毒亚单位疫苗及lt作为该疫苗佐剂的用途
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CN109265542B (zh) * 2018-09-27 2021-06-15 国药中生生物技术研究院有限公司 特异性结合诺如病毒gii.4基因型vp1蛋白或vlp的抗体及其制备方法和应用
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CN117098846A (zh) 2021-03-29 2023-11-21 电化株式会社 诺如病毒来源的肽、多核苷酸、抗体、组合物、鉴定诺如病毒的中和表位的方法
JP2024519800A (ja) 2021-05-21 2024-05-21 タケダ ワクチン，インコーポレイテッド 固体組成物、フリーズドライ方法およびガラスバイアル
CN118252924A (zh) * 2022-12-27 2024-06-28 远大赛威信生命科学(南京)有限公司 用于诱发哺乳动物针对诺如病毒的免疫反应的药物组合物及其制备方法和用途
WO2025076792A1 (en) * 2023-10-12 2025-04-17 Chengdu Kanghua Biological Product Co., Ltd. Methods of preparing norovirus vaccine with low amounts of adjuvant
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UA117732C2 (uk) 2018-09-25
DOP2022000030A (es) 2022-06-30
EP2731621B1 (en) 2017-11-01
CN103874507A (zh) 2014-06-18
US20180185468A1 (en) 2018-07-05
US20230338503A1 (en) 2023-10-26
CA2841356A1 (en) 2013-01-17
JP6208659B2 (ja) 2017-10-04
US20160000899A1 (en) 2016-01-07
PH12018501515A1 (en) 2019-02-04
EA202090699A2 (ru) 2020-07-31
ZA201401012B (en) 2015-05-27
MX356586B (es) 2018-06-05
EA201792407A2 (ru) 2018-03-30
ES2656527T3 (es) 2018-02-27
HK1198136A1 (en) 2015-03-13
ES2926487T3 (es) 2022-10-26
US10675341B2 (en) 2020-06-09
PH12014500093A1 (en) 2014-03-17
EA202090699A3 (ru) 2020-11-30
HK1215154A1 (zh) 2016-08-19
AU2012282658A1 (en) 2013-03-14
WO2013009849A1 (en) 2013-01-17
EP3299030A1 (en) 2018-03-28
AU2012282658B2 (en) 2014-11-27
US20130273102A1 (en) 2013-10-17
US9801934B2 (en) 2017-10-31
CR20190540A (es) 2022-04-04
US11701420B2 (en) 2023-07-18
MA35414B1 (fr) 2014-09-01
MY170746A (en) 2019-08-27
PH12021551773A1 (en) 2022-08-01
EA201792407A3 (ru) 2018-07-31
EP3299030B1 (en) 2022-06-08
US20210085778A1 (en) 2021-03-25
PL2731621T3 (pl) 2018-10-31
PE20140845A1 (es) 2014-08-03
EP2731621A1 (en) 2014-05-21
ZA201500915B (en) 2016-06-29
EA029470B1 (ru) 2018-03-30
CN105031637A (zh) 2015-11-11
PH12018501515B1 (en) 2022-02-18
JP6613259B2 (ja) 2019-11-27
AU2015200836B2 (en) 2016-08-25
NZ620865A (en) 2015-08-28
JP2017214357A (ja) 2017-12-07
IL230356B (en) 2019-05-30
JP2014520852A (ja) 2014-08-25
CR20140069A (es) 2014-06-27
AU2015200836A1 (en) 2015-03-12
US9867876B2 (en) 2018-01-16
CL2014000082A1 (es) 2014-07-04
EA201490258A1 (ru) 2014-05-30
CA2841356C (en) 2022-03-01
DOP2014000004A (es) 2014-10-31
BR112014000656A2 (pt) 2017-02-14
TN2014000008A1 (en) 2015-07-01
SG10201605644WA (en) 2016-09-29
EP2731621A4 (en) 2015-03-25
MX2014000411A (es) 2014-08-26
HK1199202A1 (en) 2015-06-26
MX379496B (es) 2025-03-11
EP4112074A1 (en) 2023-01-04
KR20140066160A (ko) 2014-05-30
EA035442B1 (ru) 2020-06-17
GEP201706668B (en) 2017-05-25
CN108567975A (zh) 2018-09-25
NZ710919A (en) 2017-12-22
DK3299030T3 (da) 2022-09-05
PL3299030T3 (pl) 2022-12-05

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