CR20190540A - FORMULACIONES PARENTERALES DE VACUNAS CONTRA LOS NOVOVIRUS (Divisional 2014-0069) - Google Patents
FORMULACIONES PARENTERALES DE VACUNAS CONTRA LOS NOVOVIRUS (Divisional 2014-0069)Info
- Publication number
- CR20190540A CR20190540A CR20190540A CR20190540A CR20190540A CR 20190540 A CR20190540 A CR 20190540A CR 20190540 A CR20190540 A CR 20190540A CR 20190540 A CR20190540 A CR 20190540A CR 20190540 A CR20190540 A CR 20190540A
- Authority
- CR
- Costa Rica
- Prior art keywords
- vaccine formulations
- norovirus vaccine
- parenteral
- parenteral norovirus
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
Composiciones de vacuna parenterales de dosis individuales que comprenden mezclas de partículas tipo virus monovalentes de Norovirus. También se divulgan métodos para conferir una inmunidad protectora contra infecciones por Norovirus en un ser humano por administración de dichas composiciones.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161506447P | 2011-07-11 | 2011-07-11 | |
PCT/US2012/046222 WO2013009849A1 (en) | 2011-07-11 | 2012-07-11 | Parenteral norovirus vaccine formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20190540A true CR20190540A (es) | 2022-04-04 |
Family
ID=47506489
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20190540A CR20190540A (es) | 2011-07-11 | 2012-07-11 | FORMULACIONES PARENTERALES DE VACUNAS CONTRA LOS NOVOVIRUS (Divisional 2014-0069) |
CR20140069A CR20140069A (es) | 2011-07-11 | 2014-02-11 | Formulaciones parenterales de vacunas contra los norovirus |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20140069A CR20140069A (es) | 2011-07-11 | 2014-02-11 | Formulaciones parenterales de vacunas contra los norovirus |
Country Status (29)
Country | Link |
---|---|
US (5) | US9801934B2 (es) |
EP (3) | EP4112074A1 (es) |
JP (2) | JP6208659B2 (es) |
KR (1) | KR102096937B1 (es) |
CN (3) | CN105031637A (es) |
AU (2) | AU2012282658B2 (es) |
BR (1) | BR112014000656A2 (es) |
CA (1) | CA2841356C (es) |
CL (1) | CL2014000082A1 (es) |
CR (2) | CR20190540A (es) |
DK (1) | DK3299030T3 (es) |
DO (2) | DOP2014000004A (es) |
EA (3) | EA029470B1 (es) |
EC (1) | ECSP14013201A (es) |
ES (2) | ES2656527T3 (es) |
GE (1) | GEP201706668B (es) |
HK (3) | HK1198136A1 (es) |
IL (1) | IL230356B (es) |
MA (1) | MA35414B1 (es) |
MX (1) | MX356586B (es) |
MY (1) | MY170746A (es) |
PE (1) | PE20140845A1 (es) |
PH (1) | PH12018501515A1 (es) |
PL (2) | PL3299030T3 (es) |
SG (1) | SG10201605644WA (es) |
TN (1) | TN2014000008A1 (es) |
UA (1) | UA117732C2 (es) |
WO (1) | WO2013009849A1 (es) |
ZA (2) | ZA201401012B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2008302276B2 (en) | 2006-09-29 | 2013-10-10 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
KR101515489B1 (ko) | 2006-09-29 | 2015-04-30 | 다케다 백신즈 인코포레이티드 | 노로바이러스 백신 제제 |
US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
EA029470B1 (ru) | 2011-07-11 | 2018-03-30 | Такеда Вэксинс, Инк. | Способ стимулирования формирования защитного иммунитета против норовируса |
KR102649950B1 (ko) | 2013-10-03 | 2024-03-22 | 다케다 백신즈 인코포레이티드 | 세포주로부터 랍도바이러스를 탐지 및 제거하는 방법 |
US20160310412A1 (en) | 2013-12-16 | 2016-10-27 | Takeda Pharmaceutical Company Limited | Microneedle |
CN107184970A (zh) * | 2017-02-16 | 2017-09-22 | 北京生物制品研究所有限责任公司 | 口服诺如病毒亚单位疫苗及lt作为该疫苗佐剂的用途 |
GB201703644D0 (en) | 2017-03-07 | 2017-04-19 | Elopak As | Improvements in or relating to toller mounting arrangements |
CN110603058A (zh) * | 2017-05-15 | 2019-12-20 | 扬森疫苗与预防公司 | 含有病毒的稳定组合物 |
JP2021514391A (ja) * | 2018-02-15 | 2021-06-10 | アイコン ジェネティクス ゲーエムベーハー | ノロウイルスに対する免疫応答を生成するための免疫原性組成物及びワクチン |
US20210121511A1 (en) * | 2018-05-29 | 2021-04-29 | Unm Rainforest Innovations | Virus-like particle compositions and methods of using same |
CN109265542B (zh) * | 2018-09-27 | 2021-06-15 | 国药中生生物技术研究院有限公司 | 特异性结合诺如病毒gii.4基因型vp1蛋白或vlp的抗体及其制备方法和应用 |
AR117462A1 (es) * | 2018-12-20 | 2021-08-04 | Takeda Vaccines Inc | Vacuna contra norovirus, formulaciones y métodos |
BR112022013537A2 (pt) * | 2020-01-08 | 2022-11-22 | Bharat Biotech Int Ltd | Composições de vacina viral e métodos de preparações das mesmas |
CN117098846A (zh) | 2021-03-29 | 2023-11-21 | 电化株式会社 | 诺如病毒来源的肽、多核苷酸、抗体、组合物、鉴定诺如病毒的中和表位的方法 |
WO2022246323A1 (en) | 2021-05-21 | 2022-11-24 | Takeda Vaccines, Inc. | Solid composition, freeze-drying method and glass vial |
CN118252924A (zh) * | 2022-12-27 | 2024-06-28 | 远大赛威信生命科学(南京)有限公司 | 用于诱发哺乳动物针对诺如病毒的免疫反应的药物组合物及其制备方法和用途 |
Family Cites Families (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6572862B1 (en) | 1989-11-08 | 2003-06-03 | Baylor College Of Medicine | Methods and reagents to detect and characterize Norwalk and related viruses |
AU1893592A (en) | 1991-03-25 | 1992-10-21 | Board Of Trustees Of The Leland Stanford Junior University | Norwalk virus human gastroenteritis agent and molecular cloning of corresponding cdnas |
AU683211B2 (en) | 1992-04-08 | 1997-11-06 | United States of America as represented by The Secretary Department of Health and Human Services, The | Wild-type measles virus glycoproteins: vaccine and detection method therefor |
WO1994005700A2 (en) | 1992-09-07 | 1994-03-17 | Baylor College Of Medicine | Methods and reagents to detect and characterize norwalk and related viruses |
PL178578B1 (pl) | 1993-03-23 | 2000-05-31 | Smithkline Beecham Biolog | Zawiesina cząstek 3-0-deacylowanego monofosforylolipidu A i sposób jej wytwarzania oraz kompozycja szczepionki zawierającej antygen w połączeniu z 3-0-deacylowanym monofosforylolipidem A i sposób jej wytwarzania |
US5788970A (en) | 1994-03-29 | 1998-08-04 | The University Of Maryland College Park | Chimeric infectious bursal disease virus CDNA clones, expression products and vaccines based thereon |
SK147696A3 (en) | 1994-05-16 | 1997-08-06 | Merck & Co Inc | Isolated and purified protein of papillomavirus, a capside, a viral particle, pharmaceutical composition comprising its, a method of making them and their use |
US5645051A (en) | 1995-04-21 | 1997-07-08 | Dura Pharmaceuticals, Inc. | Unit dose dry powder inhaler |
US5861241A (en) | 1995-08-16 | 1999-01-19 | University Of Massachusetts | Monoclonal antibodies for detecting Norwalk virus |
GB9525083D0 (en) | 1995-12-07 | 1996-02-07 | Danbiosyst Uk | Vaccine compositions |
US5834015A (en) * | 1996-09-11 | 1998-11-10 | Albany Medical College | Protein-lipid vesicles and autogenous vaccine comprising the same |
US5953727A (en) | 1996-10-10 | 1999-09-14 | Incyte Pharmaceuticals, Inc. | Project-based full-length biomolecular sequence database |
US6491919B2 (en) | 1997-04-01 | 2002-12-10 | Corixa Corporation | Aqueous immunologic adjuvant compostions of monophosphoryl lipid A |
EE9900612A (et) | 1997-04-08 | 2000-08-15 | Merck & Co., Inc. | Inimese papilloomiviiruse stabiliseeritud preparaadid |
WO1998050071A1 (en) | 1997-05-01 | 1998-11-12 | Chiron Corporation | Use of virus-like particles as adjuvants |
US20040265377A1 (en) | 1997-10-27 | 2004-12-30 | Harry Seager | Solid dispersing vaccine composition for oral delivery |
CN1354787A (zh) | 1998-08-14 | 2002-06-19 | 麦克公司 | 纯化人乳头瘤病毒样颗粒的方法 |
WO2000035479A1 (en) | 1998-12-17 | 2000-06-22 | Merck & Co., Inc. | Synthetic virus-like particles with heterologous epitopes |
SI1150712T1 (sl) * | 1999-02-05 | 2009-02-28 | Merck & Co Inc | Pripravek cepiva proti humanem papiloma virusu |
KR100762092B1 (ko) | 1999-06-22 | 2007-10-04 | 국립감염증연구소장이 대표하는 일본국 | Srsv 검출 킷트 |
JP2002020399A (ja) | 2000-07-10 | 2002-01-23 | Osaka Prefecture | ノルウォークウイルス(nv)を認識するモノクローナル抗体 |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
US20040121465A1 (en) | 2002-02-14 | 2004-06-24 | Novavax, Inc. | Optimization of gene sequences of virus-like particles for expression in insect cells |
GB0206360D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
GB0206359D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
CA2849556A1 (en) | 2002-04-11 | 2003-10-23 | Vu Truong-Le | Preservation of bioactive materials by freeze dried foam |
GB0302218D0 (en) | 2003-01-30 | 2003-03-05 | Chiron Sri | Vaccine formulation & Mucosal delivery |
AU2003237528A1 (en) | 2002-06-07 | 2003-12-22 | Kentucky Bioprocessing, Llc | Flexible vaccine assembly and vaccine delivery platform |
JP4598519B2 (ja) | 2002-06-20 | 2010-12-15 | サイトス バイオテクノロジー アーゲー | アジュバントとして使用するためのパッケージ化されたウィルス様粒子:調製法及び使用法 |
WO2004075829A2 (en) | 2003-01-30 | 2004-09-10 | Chiron Corporation | Adjuvanted influenza vaccine |
EP1599188A2 (en) | 2003-02-20 | 2005-11-30 | Becton, Dickinson and Company | POWDER FORMULATIONS OF RECOMBINANT STAPHYLOCOCCAL, ENTEROTOXIN B (<SB>R</SB>SEB) MADE BY ATMOSPHERIC SPRAY-FREEZE DRYING FOR IMPROVED VACCINATION |
US8592197B2 (en) | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
WO2005032457A2 (en) | 2003-07-21 | 2005-04-14 | Boyce Thompson Institute For Plant Research, Inc. | Vectors and methods for immunization against norwalk virus using transgenic plants |
JP2007537137A (ja) | 2003-09-24 | 2007-12-20 | モンタナ ステート ユニバーシティ | ノロウィルスモノクローナル抗体及びペプチド |
WO2005037223A2 (en) | 2003-10-15 | 2005-04-28 | Brigham And Women's Hospital, Inc. | Methods and compositions for immunomodulation |
US20050215501A1 (en) | 2003-10-24 | 2005-09-29 | Coley Pharmaceutical Group, Inc. | Methods and products for enhancing epitope spreading |
FR2863890B1 (fr) | 2003-12-19 | 2006-03-24 | Aventis Pasteur | Composition immunostimulante |
US7481997B1 (en) | 2004-02-12 | 2009-01-27 | Montana State University | Snow mountain virus genome sequence, virus-like particles and methods of use |
US20050260225A1 (en) | 2004-05-18 | 2005-11-24 | Goldberg Joanna B | Intranasal recombinant Salmonella vaccine encoding heterologous polysaccharide antigens |
CU23496A1 (es) | 2004-09-03 | 2010-02-23 | Ct Ingenieria Genetica Biotech | Composición vacunal contra el virus de la hepatitis c |
WO2006044857A2 (en) | 2004-10-20 | 2006-04-27 | Acambis Inc. | Vaccines against japanese encephalitis virus and west nile virus |
GB0428394D0 (en) | 2004-12-24 | 2005-02-02 | Chiron Srl | Saccharide conjugate vaccines |
US20060177468A1 (en) | 2005-01-05 | 2006-08-10 | Philadelphia Health and Education Corporation (d/b/a Drexel University College of Medicine | Delivery vehicles, bioactive substances and viral vaccines |
WO2006086188A2 (en) | 2005-01-31 | 2006-08-17 | The Johns Hopkins University | Use of consensus sequence as vaccine antigen to enhance recognition of virulent viral variants |
EP1858919B1 (en) | 2005-02-18 | 2012-04-04 | Novartis Vaccines and Diagnostics, Inc. | Immunogens from uropathogenic escherichia coli |
CA2599218C (en) | 2005-03-18 | 2015-08-11 | Cytos Biotechnology Ag | Cat allergen conjugates and uses thereof |
BRPI0611336A2 (pt) | 2005-06-01 | 2010-08-31 | Dow Global Technologies Inc | método para produzir uma partìcula multivalente semelhante a vìrus, partìcula multivalente semelhante a vìrus, método de aumentar a solubilidade de uma partìcula multivalente semelhante a vìrus e vacina |
EP1736538A1 (en) | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Process for the preparative purification of virus-like-particles (VLPs) |
WO2007081447A2 (en) | 2005-11-22 | 2007-07-19 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and sapovirus antigens |
JP2007145775A (ja) | 2005-11-29 | 2007-06-14 | Falco Life Science:Kk | ノロウイルスgiの高感度検出方法 |
US20080029915A1 (en) * | 2006-08-02 | 2008-02-07 | Courtoy Nv | Rotary tablet press |
AU2008302276B2 (en) * | 2006-09-29 | 2013-10-10 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
KR101515489B1 (ko) * | 2006-09-29 | 2015-04-30 | 다케다 백신즈 인코포레이티드 | 노로바이러스 백신 제제 |
PL2121011T3 (pl) | 2006-12-06 | 2014-10-31 | Novartis Ag | Szczepionki zawierające antygeny czterech szczepów wirusa grypy |
JP5284290B2 (ja) * | 2007-03-14 | 2013-09-11 | リゴサイト ファーマスーティカルズ,インコーポレイテッド | ウイルス様粒子の精製 |
US8648229B2 (en) | 2007-09-12 | 2014-02-11 | Australian Centre For Plant Functional Genomics Pty Ltd | Plant seed active transcriptional control sequences |
US20100266636A1 (en) * | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
SG2013057732A (en) | 2008-08-08 | 2015-02-27 | Ligocyte Pharmaceuticals Inc | Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity |
CA2750321A1 (en) * | 2009-01-22 | 2010-07-29 | Pharmathene, Inc. | Stable vaccine compositions and methods of use |
CA2752039A1 (en) * | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccine regimens for pandemic-associated strains |
US20110070260A1 (en) | 2009-09-09 | 2011-03-24 | Baric Ralph S | Multivalent Immunogenic Compositions Against Noroviruses and Methods of Use |
KR20120125627A (ko) * | 2010-01-21 | 2012-11-16 | 리고사이트 파머슈티컬즈 인코퍼레이티드 | 칼리시바이러스 바이러스 유사 입자들 상에 표적화된 이종 항원 제공 |
EP2575773A4 (en) * | 2010-05-26 | 2014-06-25 | Selecta Biosciences Inc | SYNTHETIC NANOTRÄGERKOMBINATIONSIMPFSTOFFE |
EA029470B1 (ru) | 2011-07-11 | 2018-03-30 | Такеда Вэксинс, Инк. | Способ стимулирования формирования защитного иммунитета против норовируса |
JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
WO2017100861A1 (en) | 2015-12-16 | 2017-06-22 | The Walter And Eliza Hall Institute Of Medical Research | Inhibition of cytokine-induced sh2 protein in nk cells |
CN110520530A (zh) | 2016-10-18 | 2019-11-29 | 明尼苏达大学董事会 | 肿瘤浸润性淋巴细胞和治疗方法 |
WO2019213610A1 (en) | 2018-05-03 | 2019-11-07 | Board Of Regents, The University Of Texas System | Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade |
JP2021534074A (ja) | 2018-08-20 | 2021-12-09 | タケダ ワクチン, インコーポレイテッドTakeda Vaccines, Inc. | Vlp製剤 |
AR117462A1 (es) | 2018-12-20 | 2021-08-04 | Takeda Vaccines Inc | Vacuna contra norovirus, formulaciones y métodos |
MX2021009742A (es) | 2019-02-15 | 2021-12-10 | Editas Medicine Inc | Celulas asesinas naturales (nk) modificadas para inmunoterapia. |
-
2012
- 2012-07-11 EA EA201490258A patent/EA029470B1/ru not_active IP Right Cessation
- 2012-07-11 BR BR112014000656A patent/BR112014000656A2/pt not_active Application Discontinuation
- 2012-07-11 PL PL17199372.8T patent/PL3299030T3/pl unknown
- 2012-07-11 CN CN201510262891.2A patent/CN105031637A/zh active Pending
- 2012-07-11 EA EA201792407A patent/EA035442B1/ru not_active IP Right Cessation
- 2012-07-11 EA EA202090699A patent/EA202090699A3/ru unknown
- 2012-07-11 WO PCT/US2012/046222 patent/WO2013009849A1/en active Application Filing
- 2012-07-11 EP EP22176978.9A patent/EP4112074A1/en active Pending
- 2012-07-11 CN CN201810373895.1A patent/CN108567975A/zh active Pending
- 2012-07-11 CN CN201280043691.2A patent/CN103874507A/zh active Pending
- 2012-07-11 GE GEAP201213384A patent/GEP201706668B/en unknown
- 2012-07-11 MY MYPI2014000073A patent/MY170746A/en unknown
- 2012-07-11 CR CR20190540A patent/CR20190540A/es unknown
- 2012-07-11 DK DK17199372.8T patent/DK3299030T3/da active
- 2012-07-11 ES ES12811916.1T patent/ES2656527T3/es active Active
- 2012-07-11 PL PL12811916T patent/PL2731621T3/pl unknown
- 2012-07-11 MX MX2014000411A patent/MX356586B/es active IP Right Grant
- 2012-07-11 ES ES17199372T patent/ES2926487T3/es active Active
- 2012-07-11 AU AU2012282658A patent/AU2012282658B2/en active Active
- 2012-07-11 CA CA2841356A patent/CA2841356C/en active Active
- 2012-07-11 KR KR1020147003571A patent/KR102096937B1/ko active IP Right Grant
- 2012-07-11 EP EP12811916.1A patent/EP2731621B1/en active Active
- 2012-07-11 PE PE2014000054A patent/PE20140845A1/es active IP Right Grant
- 2012-07-11 SG SG10201605644WA patent/SG10201605644WA/en unknown
- 2012-07-11 EP EP17199372.8A patent/EP3299030B1/en active Active
- 2012-07-11 JP JP2014520273A patent/JP6208659B2/ja active Active
- 2012-11-07 UA UAA201401321A patent/UA117732C2/uk unknown
-
2013
- 2013-03-15 US US13/840,403 patent/US9801934B2/en active Active
-
2014
- 2014-01-07 TN TNP2014000008A patent/TN2014000008A1/en unknown
- 2014-01-07 IL IL230356A patent/IL230356B/en active IP Right Grant
- 2014-01-10 DO DO2014000004A patent/DOP2014000004A/es unknown
- 2014-01-10 CL CL2014000082A patent/CL2014000082A1/es unknown
- 2014-02-06 MA MA36741A patent/MA35414B1/fr unknown
- 2014-02-10 ZA ZA2014/01012A patent/ZA201401012B/en unknown
- 2014-02-11 EC ECSP14013201 patent/ECSP14013201A/es unknown
- 2014-02-11 CR CR20140069A patent/CR20140069A/es unknown
- 2014-11-21 HK HK14111772.5A patent/HK1198136A1/xx unknown
- 2014-12-18 HK HK14112697.5A patent/HK1199202A1/xx unknown
- 2014-12-18 HK HK16102061.2A patent/HK1215154A1/zh unknown
-
2015
- 2015-02-09 ZA ZA2015/00915A patent/ZA201500915B/en unknown
- 2015-02-19 AU AU2015200836A patent/AU2015200836B2/en active Active
- 2015-07-10 US US14/796,614 patent/US9867876B2/en active Active
-
2017
- 2017-05-02 JP JP2017091755A patent/JP6613259B2/ja active Active
- 2017-12-08 US US15/836,030 patent/US10675341B2/en active Active
-
2018
- 2018-07-06 PH PH12018501515A patent/PH12018501515A1/en unknown
-
2020
- 2020-06-05 US US16/894,291 patent/US11701420B2/en active Active
-
2022
- 2022-02-04 DO DO2022000030A patent/DOP2022000030A/es unknown
-
2023
- 2023-05-24 US US18/322,679 patent/US20230338503A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH12018501515A1 (en) | Parenteral novovirus vaccine formulations | |
MY168959A (en) | Vaccine compositions for the prevention of dengue virus infection | |
PH12014502875A1 (en) | Vaccine compositions for prevention against dengue virus infection | |
MX352324B (es) | Vacunas multivalentes de nanovehiculos sinteticos. | |
EP2827869A4 (en) | COMPOSITIONS AND METHODS FOR IMPROVING THE THERAPEUTIC BENEFIT OF INDIRUBIN AND ITS ANALOGUES INCLUDING MESOINDIGO | |
MD20140136A2 (ro) | Inhibitori ai virusului hepatic C | |
MX2012009581A (es) | Vacunas para su uso en la profilaxis y tratamiento de la enfermedad del virus de influenza. | |
GB201400609D0 (en) | Vaccine adjuvant composition comprising inulin particles | |
MX2013013801A (es) | Oligodesoxinucleotidos inmunoestimuladores. | |
MX346596B (es) | Oligodesoxinucleotidos inmunoestimuladores. | |
BR112015008417A8 (pt) | composição imunogênica, vacina, e, uso de uma composição imunogênica | |
PH12017500304A1 (en) | Vaccine compositions against dengue virus diseases | |
EP2931310A4 (en) | COMPOSITIONS, METHODS OF ADMINISTRATION AND USES OF TRIVALENT FORMULATIONS AGAINST DENGUE VIRUS | |
EA032913B1 (ru) | Препараты производных пиримидиндиона | |
EA201690378A1 (ru) | Вакцинные композиции против наркотической зависимости | |
EP2780009A4 (en) | METHODS AND COMPOSITIONS FOR ENHANCED IL-MEDICATION ADMINISTRATION AND EXTENDED DELIVERY FORMULATIONS | |
IN2013CH04314A (es) | ||
PH12015500708A1 (en) | Agent for enhancing immunity containing glutathione | |
UA106101C2 (uk) | Спосіб виготовлення медичних противірусних препаратів, що містять наночастинки, та препарат проти вірусів герпесу hiv і грипу h1n1, виготовлений за даним способом | |
IN2013MU03123A (es) | ||
EP2777712A4 (en) | AUXILIARY SUBSTANCES FOR POLYSACCHARIDIVES AND FORMULATIONS OBTAINED THEREFROM | |
UA106111C2 (uk) | Спосіб отримання людського інтерферону з використанням наночастинок оксиду церію |