KR102085349B1 - 세포 - Google Patents

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KR102085349B1
KR102085349B1 KR1020177019393A KR20177019393A KR102085349B1 KR 102085349 B1 KR102085349 B1 KR 102085349B1 KR 1020177019393 A KR1020177019393 A KR 1020177019393A KR 20177019393 A KR20177019393 A KR 20177019393A KR 102085349 B1 KR102085349 B1 KR 102085349B1
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KR20170092695A (ko
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마틴 풀레
숀 코르도바
시모비 오누오하
시몬 토마스
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유씨엘 비즈니스 리미티드
오토러스 리미티드
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N5/0634—Cells from the blood or the immune system
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    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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  • General Engineering & Computer Science (AREA)
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  • Plant Pathology (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Developmental Biology & Embryology (AREA)
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KR1020177019393A 2014-12-24 2015-12-23 세포 Active KR102085349B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201423172 2014-12-24
GB1423172.4 2014-12-24
PCT/GB2015/054137 WO2016102965A1 (en) 2014-12-24 2015-12-23 Cell

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020197038792A Division KR20200003939A (ko) 2014-12-24 2015-12-23 세포

Publications (2)

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KR20170092695A KR20170092695A (ko) 2017-08-11
KR102085349B1 true KR102085349B1 (ko) 2020-03-06

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ID=55066668

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KR1020177019393A Active KR102085349B1 (ko) 2014-12-24 2015-12-23 세포
KR1020227031979A Ceased KR20220129684A (ko) 2014-12-24 2015-12-23 세포
KR1020197038792A Ceased KR20200003939A (ko) 2014-12-24 2015-12-23 세포
KR1020217024459A Active KR102376244B1 (ko) 2014-12-24 2015-12-23 세포
KR1020237036909A Pending KR20230152824A (ko) 2014-12-24 2015-12-23 세포
KR1020217024458A Active KR102376242B1 (ko) 2014-12-24 2015-12-23 세포

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KR1020227031979A Ceased KR20220129684A (ko) 2014-12-24 2015-12-23 세포
KR1020197038792A Ceased KR20200003939A (ko) 2014-12-24 2015-12-23 세포
KR1020217024459A Active KR102376244B1 (ko) 2014-12-24 2015-12-23 세포
KR1020237036909A Pending KR20230152824A (ko) 2014-12-24 2015-12-23 세포
KR1020217024458A Active KR102376242B1 (ko) 2014-12-24 2015-12-23 세포

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US (8) US11091532B2 (enExample)
EP (3) EP4368704A3 (enExample)
JP (5) JP6633081B2 (enExample)
KR (6) KR102085349B1 (enExample)
CN (2) CN107002045B (enExample)
AU (5) AU2015370679C1 (enExample)
BR (1) BR112017013690A2 (enExample)
CA (2) CA2970440A1 (enExample)
CL (3) CL2017001314A1 (enExample)
DK (2) DK3560953T5 (enExample)
ES (2) ES2976197T3 (enExample)
FI (1) FI3560953T3 (enExample)
HR (1) HRP20240357T1 (enExample)
HU (2) HUE066020T2 (enExample)
IL (4) IL274903B (enExample)
LT (1) LT3560953T (enExample)
MX (1) MX2017006233A (enExample)
PL (2) PL3560953T3 (enExample)
PT (2) PT3560953T (enExample)
RS (1) RS65343B1 (enExample)
RU (2) RU2768019C2 (enExample)
SG (2) SG11201704084VA (enExample)
SI (1) SI3560953T1 (enExample)
SM (1) SMT202400134T1 (enExample)
WO (1) WO2016102965A1 (enExample)
ZA (1) ZA201703381B (enExample)

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GB201415347D0 (en) * 2014-08-29 2014-10-15 Ucl Business Plc Signalling system
PT3560953T (pt) 2014-12-24 2024-03-26 Autolus Ltd Célula
PL3253865T3 (pl) 2015-02-06 2022-10-10 National University Of Singapore Sposoby wzmacniania skuteczności terapeutycznych komórek odpornościowych
SG10201908203SA (en) 2015-03-05 2019-10-30 Hutchinson Fred Cancer Res Immunomodulatory Fusion Proteins And Uses Thereof
GB201503742D0 (en) 2015-03-05 2015-04-22 Ucl Business Plc Chimeric antigen receptor
PT3280729T (pt) 2015-04-08 2022-08-01 Novartis Ag Terapias para cd20, terapias para cd22 e terapias de combinação com uma célula que expressa o recetor de antigénio quimérico (car) para cd19
GB201507119D0 (en) * 2015-04-27 2015-06-10 Ucl Business Plc Nucleic Acid Construct
GB201507115D0 (en) * 2015-04-27 2015-06-10 Ucl Business Plc Nucleic Acid Construct
US11173179B2 (en) 2015-06-25 2021-11-16 Icell Gene Therapeutics Llc Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof
TW202444897A (zh) 2015-06-25 2024-11-16 美商生物細胞基因治療有限公司 嵌合抗原受體(car)、組合物及其使用方法
CA3019835A1 (en) 2016-04-08 2017-10-12 Purdue Research Foundation Methods and compositions for car t cell therapy
GB201610512D0 (en) 2016-06-16 2016-08-03 Autolus Ltd Chimeric antigen receptor
GB201610515D0 (en) * 2016-06-16 2016-08-03 Autolus Ltd Cell
CA3029197A1 (en) * 2016-06-24 2017-12-28 Icell Gene Therapeutics Llc Chimeric antigen receptors (cars), compositions and methods thereof
EP4282969A3 (en) * 2016-09-02 2024-01-31 Lentigen Technology, Inc. Compositions and methods for treating cancer with duocars
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