KR101916928B1 - 조성물 - Google Patents

조성물 Download PDF

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Publication number
KR101916928B1
KR101916928B1 KR1020147004436A KR20147004436A KR101916928B1 KR 101916928 B1 KR101916928 B1 KR 101916928B1 KR 1020147004436 A KR1020147004436 A KR 1020147004436A KR 20147004436 A KR20147004436 A KR 20147004436A KR 101916928 B1 KR101916928 B1 KR 101916928B1
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KR
South Korea
Prior art keywords
compound
delete delete
composition
nanograms
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020147004436A
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English (en)
Korean (ko)
Other versions
KR20140049001A (ko
Inventor
클레어 루이즈 앰버리
크리스토퍼 데이비드 에드워즈
Original Assignee
글락소스미스클라인 엘엘씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of KR20140049001A publication Critical patent/KR20140049001A/ko
Application granted granted Critical
Publication of KR101916928B1 publication Critical patent/KR101916928B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020147004436A 2011-07-22 2012-07-19 조성물 Expired - Fee Related KR101916928B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161510624P 2011-07-22 2011-07-22
US61/510,624 2011-07-22
PCT/EP2012/064139 WO2013014052A1 (en) 2011-07-22 2012-07-19 Composition

Publications (2)

Publication Number Publication Date
KR20140049001A KR20140049001A (ko) 2014-04-24
KR101916928B1 true KR101916928B1 (ko) 2018-11-08

Family

ID=46581948

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147004436A Expired - Fee Related KR101916928B1 (ko) 2011-07-22 2012-07-19 조성물

Country Status (20)

Country Link
US (2) US10112946B2 (https=)
EP (1) EP2734186B1 (https=)
JP (1) JP2014520874A (https=)
KR (1) KR101916928B1 (https=)
CN (1) CN103841958A (https=)
AU (2) AU2012289042A1 (https=)
BR (1) BR112014001425A2 (https=)
CA (1) CA2841361A1 (https=)
CY (1) CY1120802T1 (https=)
DK (1) DK2734186T3 (https=)
ES (1) ES2693122T3 (https=)
HR (1) HRP20181667T1 (https=)
LT (1) LT2734186T (https=)
PL (1) PL2734186T3 (https=)
PT (1) PT2734186T (https=)
RS (1) RS57995B1 (https=)
RU (1) RU2631482C2 (https=)
SI (1) SI2734186T1 (https=)
SM (1) SMT201800642T1 (https=)
WO (1) WO2013014052A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA103195C2 (uk) 2008-08-11 2013-09-25 Глаксосмитклайн Ллк Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
HRP20181667T1 (hr) 2011-07-22 2018-12-14 Glaxosmithkline Llc Pripravak
EA026354B1 (ru) 2012-08-24 2017-03-31 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Пиразолопиримидиновые соединения
BR112015011439A2 (pt) 2012-11-20 2017-07-11 Glaxosmithkline Llc composto, composição farmacêutica, composição de vacina, e, uso de um composto
EA028480B1 (ru) 2012-11-20 2017-11-30 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Новые соединения
AU2013348217B2 (en) 2012-11-20 2016-10-06 Glaxosmithkline Llc Novel compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010111406A2 (en) 2009-03-24 2010-09-30 Myriad Pharmaceuticals, Inc. Compounds and therapeutic uses thereof

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Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010111406A2 (en) 2009-03-24 2010-09-30 Myriad Pharmaceuticals, Inc. Compounds and therapeutic uses thereof

Also Published As

Publication number Publication date
DK2734186T3 (en) 2019-01-07
AU2016202513B2 (en) 2018-03-22
JP2014520874A (ja) 2014-08-25
US20190023707A1 (en) 2019-01-24
RU2013157398A (ru) 2015-08-27
HRP20181667T1 (hr) 2018-12-14
PL2734186T3 (pl) 2019-01-31
US20140288099A1 (en) 2014-09-25
LT2734186T (lt) 2018-12-10
KR20140049001A (ko) 2014-04-24
EP2734186A1 (en) 2014-05-28
RS57995B1 (sr) 2019-01-31
BR112014001425A2 (pt) 2017-11-21
RU2631482C2 (ru) 2017-09-22
EP2734186B1 (en) 2018-09-12
CN103841958A (zh) 2014-06-04
ES2693122T3 (es) 2018-12-07
SI2734186T1 (sl) 2018-11-30
WO2013014052A1 (en) 2013-01-31
CY1120802T1 (el) 2019-12-11
CA2841361A1 (en) 2013-01-31
SMT201800642T1 (it) 2019-01-11
US10112946B2 (en) 2018-10-30
PT2734186T (pt) 2018-12-17
AU2012289042A1 (en) 2014-03-13

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