KR101853513B1 - 감염, 염증, 호흡기 질환 등의 치료를 위해 사용되는 ｔｌｒ2 효능제로서의 화합물 (시스테인 기재 리포펩티드) 및 조성물 - Google Patents

감염, 염증, 호흡기 질환 등의 치료를 위해 사용되는 ｔｌｒ2 효능제로서의 화합물 (시스테인 기재 리포펩티드) 및 조성물 Download PDF

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KR101853513B1
KR101853513B1 KR1020127027449A KR20127027449A KR101853513B1 KR 101853513 B1 KR101853513 B1 KR 101853513B1 KR 1020127027449 A KR1020127027449 A KR 1020127027449A KR 20127027449 A KR20127027449 A KR 20127027449A KR 101853513 B1 KR101853513 B1 KR 101853513B1
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amino
alkyl
thia
formula
thio
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KR20130012068A (ko
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탐 야오-샹 우
예펀 쩌우
티모시 지. 호프만
지안펑 판
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노파르티스 아게
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
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    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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KR1020127027449A 2010-03-23 2011-03-23 감염, 염증, 호흡기 질환 등의 치료를 위해 사용되는 ｔｌｒ2 효능제로서의 화합물 (시스테인 기재 리포펩티드) 및 조성물 Expired - Fee Related KR101853513B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31655110P 2010-03-23 2010-03-23
US61/316,551 2010-03-23
PCT/US2011/029661 WO2011119759A1 (en) 2010-03-23 2011-03-23 Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.

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KR20130012068A KR20130012068A (ko) 2013-01-31
KR101853513B1 true KR101853513B1 (ko) 2018-04-30

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KR1020127027449A Expired - Fee Related KR101853513B1 (ko) 2010-03-23 2011-03-23 감염, 염증, 호흡기 질환 등의 치료를 위해 사용되는 ｔｌｒ2 효능제로서의 화합물 (시스테인 기재 리포펩티드) 및 조성물

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US (2) US8808703B2 (enExample)
EP (1) EP2549990A1 (enExample)
JP (1) JP5848748B2 (enExample)
KR (1) KR101853513B1 (enExample)
CN (1) CN102905703B (enExample)
AU (1) AU2011232421B2 (enExample)
CA (1) CA2792938C (enExample)
EA (2) EA023725B1 (enExample)
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CN102905703A (zh) 2013-01-30
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