KR101851130B1 - Ｃｋ2 억제제로서 피라졸로피리미딘 및 관련된 헤테로사이클 - Google Patents

Ｃｋ2 억제제로서 피라졸로피리미딘 및 관련된 헤테로사이클 Download PDF

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KR101851130B1
KR101851130B1 KR1020127017450A KR20127017450A KR101851130B1 KR 101851130 B1 KR101851130 B1 KR 101851130B1 KR 1020127017450 A KR1020127017450 A KR 1020127017450A KR 20127017450 A KR20127017450 A KR 20127017450A KR 101851130 B1 KR101851130 B1 KR 101851130B1
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KR20130067486A (ko
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무스타파 하다치
조 에이. 트란
파브리스 피에르
콜린 에프. 레건
니콜라스 비. 라파엘
수치트라 라불라
데이비드 엠. 릭먼
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센화 바이오사이언시즈 인코포레이티드
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    • C07—ORGANIC CHEMISTRY
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127017450A 2009-12-04 2010-11-15 Ｃｋ2 억제제로서 피라졸로피리미딘 및 관련된 헤테로사이클 Active KR101851130B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26680109P 2009-12-04 2009-12-04
US61/266,801 2009-12-04
US35416510P 2010-06-11 2010-06-11
US61/354,165 2010-06-11
PCT/US2010/056712 WO2011068667A1 (en) 2009-12-04 2010-11-15 Pyrazolopyrimidines and related heterocycles as ck2 inhibitors

Publications (2)

Publication Number Publication Date
KR20130067486A KR20130067486A (ko) 2013-06-25
KR101851130B1 true KR101851130B1 (ko) 2018-04-23

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US (2) US8575177B2 (https=)
EP (1) EP2509602B9 (https=)
JP (1) JP5802676B2 (https=)
KR (1) KR101851130B1 (https=)
CN (1) CN102762208A (https=)
AU (1) AU2010326268B2 (https=)
BR (1) BR112012013508A2 (https=)
CA (1) CA2782684C (https=)
ES (1) ES2629170T3 (https=)
IL (1) IL220086B (https=)
PL (1) PL2509602T3 (https=)
RU (1) RU2607453C2 (https=)
SG (1) SG181507A1 (https=)
WO (1) WO2011068667A1 (https=)

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