KR101835386B1 - 트랜스티레틴 발현의 조절 - Google Patents

트랜스티레틴 발현의 조절 Download PDF

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KR101835386B1
KR101835386B1 KR1020127031119A KR20127031119A KR101835386B1 KR 101835386 B1 KR101835386 B1 KR 101835386B1 KR 1020127031119 A KR1020127031119 A KR 1020127031119A KR 20127031119 A KR20127031119 A KR 20127031119A KR 101835386 B1 KR101835386 B1 KR 101835386B1
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KR20130098162A (ko
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브렛 피. 모니아
수잔 엠. 프레이어
앤드류 엠. 시우코우스키
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아이오니스 파마수티컬즈, 인코포레이티드
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KR1020127031119A 2010-04-29 2011-04-29 트랜스티레틴 발현의 조절 Active KR101835386B1 (ko)

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US32953810P 2010-04-29 2010-04-29
US61/329,538 2010-04-29
US40516310P 2010-10-20 2010-10-20
US61/405,163 2010-10-20
PCT/US2011/034661 WO2011139917A1 (en) 2010-04-29 2011-04-29 Modulation of transthyretin expression

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KR101835386B1 true KR101835386B1 (ko) 2018-03-08

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EP (1) EP2563920B1 (OSRAM)
JP (1) JP5896175B2 (OSRAM)
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CN (1) CN103038345B (OSRAM)
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WO2010048228A2 (en) 2008-10-20 2010-04-29 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of transthyretin
JP5723378B2 (ja) 2009-11-03 2015-05-27 アルナイラム ファーマシューティカルズ， インコーポレイテッドＡｌｎｙｌａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． トランスサイレチン（ｔｔｒ）を阻害する脂質製剤化組成物及び方法
JP5896175B2 (ja) * 2010-04-29 2016-03-30 アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． トランスサイレチン発現の調節
EP2756080B1 (en) 2011-09-14 2019-02-20 Translate Bio MA, Inc. Multimeric oligonucleotide compounds
AU2012340159B2 (en) * 2011-11-18 2017-09-07 Alnylam Pharmaceuticals, Inc. RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases
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