KR101709826B1 - 신규 pcr 서열화 방법 및 hla 제노타이핑에서의 상기 방법의 사용 - Google Patents

신규 pcr 서열화 방법 및 hla 제노타이핑에서의 상기 방법의 사용 Download PDF

Info

Publication number
KR101709826B1
KR101709826B1 KR1020137002332A KR20137002332A KR101709826B1 KR 101709826 B1 KR101709826 B1 KR 101709826B1 KR 1020137002332 A KR1020137002332 A KR 1020137002332A KR 20137002332 A KR20137002332 A KR 20137002332A KR 101709826 B1 KR101709826 B1 KR 101709826B1
Authority
KR
South Korea
Prior art keywords
hla
dna
primer
pcr
sequencing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020137002332A
Other languages
English (en)
Korean (ko)
Other versions
KR20130038353A (ko
Inventor
지안 리
쉬핑 첸
시안동 장
잉 리우
카이펀 장
타오 리우
메이루 자오
Original Assignee
비지아이 제노믹스 코포레이션 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201010213717.6A external-priority patent/CN101921840B/zh
Priority claimed from CN 201010213721 external-priority patent/CN101921842B/zh
Priority claimed from CN201010213719.5A external-priority patent/CN101921841B/zh
Priority claimed from PCT/CN2010/002149 external-priority patent/WO2012083505A1/zh
Priority claimed from PCT/CN2010/002150 external-priority patent/WO2012083506A1/zh
Application filed by 비지아이 제노믹스 코포레이션 리미티드 filed Critical 비지아이 제노믹스 코포레이션 리미티드
Publication of KR20130038353A publication Critical patent/KR20130038353A/ko
Application granted granted Critical
Publication of KR101709826B1 publication Critical patent/KR101709826B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
KR1020137002332A 2010-06-30 2011-06-30 신규 pcr 서열화 방법 및 hla 제노타이핑에서의 상기 방법의 사용 Active KR101709826B1 (ko)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
CN201010213719.5 2010-06-30
CN201010213717.6A CN101921840B (zh) 2010-06-30 2010-06-30 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法
CN 201010213721 CN101921842B (zh) 2010-06-30 2010-06-30 Hla-a,b基因分型用pcr引物及其使用方法
CN201010213717.6 2010-06-30
CN201010213721.2 2010-06-30
CN201010213719.5A CN101921841B (zh) 2010-06-30 2010-06-30 基于Illumina GA测序技术的HLA基因高分辨率分型方法
CNPCT/CN2010/002149 2010-12-24
PCT/CN2010/002149 WO2012083505A1 (zh) 2010-12-24 2010-12-24 Hla-c基因分型的方法及其相关引物
PCT/CN2010/002150 WO2012083506A1 (zh) 2010-12-24 2010-12-24 Hla-dqb1基因分型的方法及其相关引物
CNPCT/CN2010/002150 2010-12-24
PCT/CN2011/076688 WO2012000445A1 (zh) 2010-06-30 2011-06-30 新的的pcr测序方法及其在hla基因分型中的应用

Publications (2)

Publication Number Publication Date
KR20130038353A KR20130038353A (ko) 2013-04-17
KR101709826B1 true KR101709826B1 (ko) 2017-02-24

Family

ID=45401405

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137002332A Active KR101709826B1 (ko) 2010-06-30 2011-06-30 신규 pcr 서열화 방법 및 hla 제노타이핑에서의 상기 방법의 사용

Country Status (12)

Country Link
US (1) US9957564B2 (https=)
EP (1) EP2599877B1 (https=)
JP (1) JP5968879B2 (https=)
KR (1) KR101709826B1 (https=)
AU (1) AU2011274090B2 (https=)
BR (1) BR112012032586B1 (https=)
CA (1) CA2803940C (https=)
DK (1) DK2599877T3 (https=)
MY (1) MY173793A (https=)
RU (1) RU2587606C2 (https=)
SG (1) SG186876A1 (https=)
WO (1) WO2012000445A1 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3597772A1 (en) * 2013-04-17 2020-01-22 Agency For Science, Technology And Research Method for generating extended sequence reads
JP6308724B2 (ja) * 2013-05-09 2018-04-11 ジェノダイブファーマ株式会社 Hla遺伝子のマルチプレックスdnaタイピング方法及びキット
US10508311B2 (en) * 2013-08-26 2019-12-17 The Translational Genomics Research Institute Single molecule-overlapping read analysis for minor variant mutation detection in pathogen samples
GB201409282D0 (en) 2014-05-23 2014-07-09 Univ Sydney Tech Sequencing process
EP3842544A1 (en) * 2014-09-05 2021-06-30 QIAGEN GmbH Preparation of adapter-ligated amplicons
DK3192869T3 (da) * 2014-09-12 2019-05-20 Mgi Tech Co Ltd Isoleret oligonukleotid og anvendelse deraf i nukleinsyresekvensering
CN105400864B (zh) * 2014-09-12 2020-04-14 深圳华大基因股份有限公司 用于基于血液样品构建测序文库的方法及其在确定胎儿遗传异常中的用途
US10233490B2 (en) 2014-11-21 2019-03-19 Metabiotech Corporation Methods for assembling and reading nucleic acid sequences from mixed populations
US9618474B2 (en) 2014-12-18 2017-04-11 Edico Genome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US10006910B2 (en) 2014-12-18 2018-06-26 Agilome, Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
US9859394B2 (en) 2014-12-18 2018-01-02 Agilome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
CA2971589C (en) 2014-12-18 2021-09-28 Edico Genome Corporation Chemically-sensitive field effect transistor
US10020300B2 (en) 2014-12-18 2018-07-10 Agilome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US9857328B2 (en) 2014-12-18 2018-01-02 Agilome, Inc. Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same
WO2016124069A1 (zh) * 2015-02-04 2016-08-11 深圳华大基因研究院 一种构建长片段测序文库的方法
KR101651817B1 (ko) * 2015-10-28 2016-08-29 대한민국 Ngs 라이브러리 제작용 프라이머 세트 및 이를 이용한 ngs 라이브러리 제작방법 및 키트
US20190048413A1 (en) * 2016-02-23 2019-02-14 Novozymes A/S Improved next-generation sequencing
WO2017201081A1 (en) 2016-05-16 2017-11-23 Agilome, Inc. Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids
IL266197B2 (en) 2016-10-24 2024-03-01 Geneinfosec Inc Hiding information contained within nucleic acids
US11441188B2 (en) 2016-11-15 2022-09-13 Quest Diagnostics Investments Llc Methods for detecting DNA mutations using Mitra tip extraction
WO2018093723A1 (en) * 2016-11-15 2018-05-24 Quest Diagnostics Investments Llc Methods for detecting cystic fibrosis mutations using mitra tip extraction
EP3626835A1 (en) 2018-09-18 2020-03-25 Sistemas Genómicos, S.L. Method for genotypically identifying both alleles of at least one locus of a subject's hla gene
RU2703394C1 (ru) * 2018-10-24 2019-10-16 Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" Способ выявления и генотипирования РНК вируса репродуктивно-респираторного синдрома свиней
RU2703401C1 (ru) * 2018-10-24 2019-10-16 Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" Тест-система для выявления и генотипирования РНК вируса репродуктивно-респираторного синдрома свиней
FR3100820B1 (fr) 2019-09-12 2024-06-28 Bionobis Procédé de génotypage adapté au traitement d’un grand nombre d’échantillons, notamment en cas de polymorphisme élevé
FR3106596B1 (fr) 2020-01-27 2022-12-02 Bionobis Procede de genotypage hla simple et rapide
CN111235266B (zh) * 2020-03-10 2023-12-01 广州医科大学附属第二医院 Hla亚型检测试剂盒及其应用
FR3110178B1 (fr) * 2020-05-18 2022-05-27 Bionobis Procédé de génotypage adapté au traitement simultané d’un grand nombre de patients
CN112553313A (zh) * 2020-12-30 2021-03-26 武汉康圣达医学检验所有限公司 用于Sanger法的测序反应产物的变性方法
KR102507110B1 (ko) * 2022-02-15 2023-03-07 주식회사 네오젠티씨 주조직 적합성 복합체의 타입들을 분석하기 위한 방법 및 장치

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007037678A2 (en) * 2005-09-29 2007-04-05 Keygene N.V. High throughput screening of mutagenized populations
WO2007073165A1 (en) * 2005-12-22 2007-06-28 Keygene N.V. Method for high-throughput aflp-based polymorphism detection

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07500734A (ja) 1991-10-31 1995-01-26 ユニヴァーシティ オブ ピッツバーグ オリゴヌクレオチドプローブのポリマーを用いる核酸配列の検出方法
US5580730A (en) * 1994-08-19 1996-12-03 Olympus America, Inc. Enzyme digestion method for the detection of amplified DNA
US6287764B1 (en) * 1997-02-11 2001-09-11 William H. Hildebrand Class I sequence based typing of HLA-A, -B, and -C alleles by direct DNA sequencing
EP0953650A1 (en) * 1998-04-20 1999-11-03 Innogenetics N.V. Method for typing of HLA alleles
CA2513899C (en) 2003-01-29 2013-03-26 454 Corporation Methods of amplifying and sequencing nucleic acids
US7300755B1 (en) * 2003-05-12 2007-11-27 Fred Hutchinson Cancer Research Center Methods for haplotyping genomic DNA
EP1711621A4 (en) * 2003-10-28 2008-06-18 Dynal Biotech Llc PRIMERS, METHODS AND KITS FOR THE AMPLIFICATION OR DETECTION OF HUMAN LEUKOCYTE ANTIGEN ALLELES
WO2006122215A2 (en) * 2005-05-10 2006-11-16 State Of Oregon Acting By & Through The State Board Of Higher Education On Behalf Of The University Of Oregon Methods of mapping polymorphisms and polymorphism microarrays
WO2007044091A2 (en) * 2005-06-02 2007-04-19 Fluidigm Corporation Analysis using microfluidic partitioning devices
JP5166276B2 (ja) 2005-11-14 2013-03-21 ケイヘーネ・エヌ・ブイ トランスポゾンタギング集団のハイスループットスクリーニングおよび挿入部位の大規模並行配列特定のための方法
WO2007140540A2 (en) * 2006-06-09 2007-12-13 Conexio 4 Pty Ltd Identification of a nucleic acid molecule
US20100086914A1 (en) * 2008-10-03 2010-04-08 Roche Molecular Systems, Inc. High resolution, high throughput hla genotyping by clonal sequencing
CN102124125A (zh) 2007-10-16 2011-07-13 霍夫曼-拉罗奇有限公司 通过克隆性测序的高分辨率、高通量hla基因分型
RU2393231C1 (ru) * 2008-12-29 2010-06-27 Федеральное государственное учреждение здравоохранения "Российский научно-исследовательский противочумный институт "Микроб" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека ("РосНИПЧИ "Микроб") Способ определения генетического родства штаммов холерных вибрионов методом секвенирования генов, фланкирующих кластер генов биосинтеза о-антигена
CN101921840B (zh) * 2010-06-30 2014-06-25 深圳华大基因科技有限公司 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法
CN101921841B (zh) 2010-06-30 2014-03-12 深圳华大基因科技有限公司 基于Illumina GA测序技术的HLA基因高分辨率分型方法
CN101921842B (zh) * 2010-06-30 2013-08-07 深圳华大基因科技有限公司 Hla-a,b基因分型用pcr引物及其使用方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007037678A2 (en) * 2005-09-29 2007-04-05 Keygene N.V. High throughput screening of mutagenized populations
WO2007073165A1 (en) * 2005-12-22 2007-06-28 Keygene N.V. Method for high-throughput aflp-based polymorphism detection

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Bentley G., et al., Tissue Antigens. Vol.74(5), pp.393-403 (2009. 11.)*
Kozarewa I., et al., Nat Methods. Vol.6(4), pp.291-295 (2009. 4.)*

Also Published As

Publication number Publication date
DK2599877T3 (da) 2017-11-20
CA2803940A1 (en) 2012-01-05
CA2803940C (en) 2019-07-02
AU2011274090A1 (en) 2013-02-07
RU2013103795A (ru) 2014-08-20
SG186876A1 (en) 2013-02-28
MY173793A (en) 2020-02-24
EP2599877A4 (en) 2014-01-01
AU2011274090B2 (en) 2015-04-09
KR20130038353A (ko) 2013-04-17
US20130237432A1 (en) 2013-09-12
BR112012032586B1 (pt) 2021-08-17
BR112012032586A2 (pt) 2019-07-30
US9957564B2 (en) 2018-05-01
JP5968879B2 (ja) 2016-08-10
WO2012000445A1 (zh) 2012-01-05
JP2013529472A (ja) 2013-07-22
EP2599877A1 (en) 2013-06-05
EP2599877B1 (en) 2017-09-27
RU2587606C2 (ru) 2016-06-20

Similar Documents

Publication Publication Date Title
KR101709826B1 (ko) 신규 pcr 서열화 방법 및 hla 제노타이핑에서의 상기 방법의 사용
CN101921840B (zh) 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法
CN111676318B (zh) 新型冠状病毒全基因组的扩增引物和方法
CN116323979A (zh) 用于hla分型的方法、组合物和试剂盒
CN108060227A (zh) 一种检测pah基因突变的扩增引物、试剂盒及其检测方法
CN111286548A (zh) 基于二代测序技术检测68个基因座的试剂盒及其使用的引物组合
CN109680040A (zh) 一种针对FFPE和cfDNA的DNA二代测序文库构建的试剂盒及其应用
CN114657269B (zh) 一组常染色体微单倍型遗传标记以及用于检测该组遗传标记的引物组
CN120060455B (zh) 基于三代测序平台的hla基因扩增引物及其应用
CN103270170B (zh) Hla-dqb1基因分型的方法及其相关引物
CN103261438B (zh) Hla-c基因分型的方法及其相关引物
CN114540486A (zh) 一种hla-dpa1基因全长扩增引物组、分型试剂盒
RU2829344C1 (ru) Способ пробоподготовки образцов для типирования генов главного комплекса гистосовместимости HLA-A, HLA-B, HLA-C, HLA-DPB1, HLA-DQB1, HLA-DRB1 и олигонуклеотидные праймеры для его реализации
JP5143450B2 (ja) Hla−bローカスにおける新規アリル
RU2837865C1 (ru) Способ секвенирования экзонов гена HLA-DPA1 и набор синтетических олигонуклеотидов для его реализации
CN114717337B (zh) 一种细胞交叉污染检测方法及其应用
CN103289994B (zh) 用于扩增T细胞受体α链CDR3编码序列的引物组合物及其用途
KR20260011275A (ko) A형 간염 바이러스 검출용 다중 복합 프라이머 세트 및 a형 간염 바이러스 전장 유전체 서열 획득 방법
HK1185114B (en) Method for hla-c genotyping and related primers thereof
WO2025018304A1 (ja) 1種以上のhla-dp遺伝子用プライマー
WO2026042842A1 (ja) Hla-drb遺伝子用プライマーのセット
WO2013097744A1 (zh) 用于扩增cdr3编码序列的引物组合物及其用途
JP2010162020A (ja) 新規hla−drb1遺伝子およびその用途
HK1185115B (en) Method for hla-dqb1 genotyping and related primers thereof

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

N231 Notification of change of applicant
PN2301 Change of applicant

St.27 status event code: A-3-3-R10-R13-asn-PN2301

St.27 status event code: A-3-3-R10-R11-asn-PN2301

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E601 Decision to refuse application
PE0601 Decision on rejection of patent

St.27 status event code: N-2-6-B10-B15-exm-PE0601

X091 Application refused [patent]
AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PX0901 Re-examination

St.27 status event code: A-2-3-E10-E12-rex-PX0901

PX0701 Decision of registration after re-examination

St.27 status event code: A-3-4-F10-F13-rex-PX0701

X701 Decision to grant (after re-examination)
GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20200129

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE)

Year of fee payment: 10