KR101672114B1 - 항암제에서 기인하는 말초성 신경 장해성 동통의 예방 및/또는 치료제 - Google Patents

항암제에서 기인하는 말초성 신경 장해성 동통의 예방 및/또는 치료제 Download PDF

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KR101672114B1
KR101672114B1 KR1020147032155A KR20147032155A KR101672114B1 KR 101672114 B1 KR101672114 B1 KR 101672114B1 KR 1020147032155 A KR1020147032155 A KR 1020147032155A KR 20147032155 A KR20147032155 A KR 20147032155A KR 101672114 B1 KR101672114 B1 KR 101672114B1
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thrombomodulin
gly
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cys
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KR20150004855A (ko
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아츠후미 가와바타
히데아키 스즈키
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갓코 호진 긴키 다이가쿠
아사히 가세이 파마 가부시키가이샤
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/366Thrombomodulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/7455Thrombomodulin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
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  • Biochemistry (AREA)
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  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020147032155A 2012-05-31 2013-05-17 항암제에서 기인하는 말초성 신경 장해성 동통의 예방 및/또는 치료제 Active KR101672114B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2012-125316 2012-05-31
JP2012125316 2012-05-31
PCT/JP2013/063743 WO2013179910A1 (ja) 2012-05-31 2013-05-17 抗癌剤に起因する末梢性神経障害性疼痛の予防及び/又は治療剤

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KR20150004855A KR20150004855A (ko) 2015-01-13
KR101672114B1 true KR101672114B1 (ko) 2016-11-02

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US (1) US10709767B2 (https=)
EP (1) EP2857037B1 (https=)
JP (3) JP6124417B2 (https=)
KR (1) KR101672114B1 (https=)
CN (1) CN104394885B (https=)
AU (1) AU2013268725B2 (https=)
BR (1) BR112014028852A2 (https=)
CA (1) CA2875069C (https=)
DK (1) DK2857037T3 (https=)
ES (1) ES2743767T3 (https=)
HU (1) HUE045997T2 (https=)
IL (1) IL235984B (https=)
IN (1) IN2014DN10075A (https=)
MX (1) MX364934B (https=)
NZ (1) NZ702242A (https=)
PL (1) PL2857037T3 (https=)
PT (1) PT2857037T (https=)
RU (1) RU2595857C2 (https=)
WO (1) WO2013179910A1 (https=)
ZA (1) ZA201408769B (https=)

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JP6325036B2 (ja) * 2016-08-19 2018-05-16 株式会社明治 抗がん剤に起因する末梢神経障害を改善するための組成物
MX394717B (es) * 2017-03-31 2025-03-24 Toray Industries Agente terapeutico o profilactico para neuropatias perifericas.
WO2019123144A1 (en) * 2017-12-19 2019-06-27 Synergia Life Sciences Pvt. Ltd. Vitamin k2 compositions for the treatment of drug induced neuropathy
US11497795B2 (en) * 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent
KR102768798B1 (ko) 2018-09-28 2025-02-14 아사히 가세이 파마 가부시키가이샤 항악성 종양제에 의한 말초 신경 장애의 증상 경감 및/또는 발증 억제를 위한 의약
RU2707954C1 (ru) * 2019-01-24 2019-12-02 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ лечения онкологической боли
JP2024507995A (ja) * 2021-02-26 2024-02-21 ヴィブロセンス ダイナミクス アー・ベー 化学療法誘発性神経障害の予測のためのバイオマーカー

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MX364934B (es) 2019-03-28
RU2595857C2 (ru) 2016-08-27
ES2743767T3 (es) 2020-02-20
JP6427284B2 (ja) 2018-11-21
JP6124417B2 (ja) 2017-05-10
IL235984B (en) 2019-09-26
US10709767B2 (en) 2020-07-14
HK1203846A1 (en) 2015-11-06
JP2017141268A (ja) 2017-08-17
AU2013268725A1 (en) 2014-12-18
PL2857037T3 (pl) 2019-12-31
CA2875069A1 (en) 2013-12-05
IN2014DN10075A (https=) 2015-08-21
ZA201408769B (en) 2015-12-23
JP6279788B2 (ja) 2018-02-14
CN104394885B (zh) 2017-06-30
EP2857037B1 (en) 2019-06-26
EP2857037A1 (en) 2015-04-08
CA2875069C (en) 2018-01-02
EP2857037A4 (en) 2016-04-06
JPWO2013179910A1 (ja) 2016-01-18
IL235984A0 (en) 2015-01-29
MX2014014505A (es) 2015-06-02
WO2013179910A1 (ja) 2013-12-05
CN104394885A (zh) 2015-03-04
KR20150004855A (ko) 2015-01-13
PT2857037T (pt) 2019-07-19
DK2857037T3 (da) 2019-07-22
US20150148296A1 (en) 2015-05-28
RU2014148171A (ru) 2016-07-20
NZ702242A (en) 2016-03-31
AU2013268725B2 (en) 2017-02-16
BR112014028852A2 (pt) 2018-04-24
HUE045997T2 (hu) 2020-01-28
JP2018095652A (ja) 2018-06-21

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