KR101614964B1 - Ｃ형 간염 바이러스 억제제로서 사용하기 위한 형태적으로 제한된 바이페닐 유도체 - Google Patents

Ｃ형 간염 바이러스 억제제로서 사용하기 위한 형태적으로 제한된 바이페닐 유도체 Download PDF

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KR101614964B1
KR101614964B1 KR1020107020259A KR20107020259A KR101614964B1 KR 101614964 B1 KR101614964 B1 KR 101614964B1 KR 1020107020259 A KR1020107020259 A KR 1020107020259A KR 20107020259 A KR20107020259 A KR 20107020259A KR 101614964 B1 KR101614964 B1 KR 101614964B1
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methyl
mmol
pyrrolidinyl
alkyl
imidazol
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KR20100121651A (ko
Inventor
캐롤 버챈드
마코넨 벨레마
대니얼 에이치. 데온
앤드루 씨. 굿
제이슨 굿리치
클린트 에이. 제임스
리코 라보이
오마르 디. 로페즈
얼레인 마르텔
니컬러스 에이. 민웰
반 엔. 응웬
제프리 리 로마인
에드워드 에이치. 뤼디거
로렌스 비. 스나이더
데니스 알. 생로랑
푸캉 양
데이비드 알. 랭글리
간 왕
로렌스 쥐. 하만
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브리스톨-마이어스 스큅 컴퍼니
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
KR1020107020259A 2008-02-13 2009-02-02 Ｃ형 간염 바이러스 억제제로서 사용하기 위한 형태적으로 제한된 바이페닐 유도체 Expired - Fee Related KR101614964B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2826608P 2008-02-13 2008-02-13
US61/028,266 2008-02-13

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KR20100121651A KR20100121651A (ko) 2010-11-18
KR101614964B1 true KR101614964B1 (ko) 2016-04-22

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US (1) US7704992B2 (https=)
EP (1) EP2242750B1 (https=)
JP (1) JP5425815B2 (https=)
KR (1) KR101614964B1 (https=)
CN (1) CN101998954B (https=)
AR (1) AR070365A1 (https=)
AU (1) AU2009215105B2 (https=)
BR (1) BRPI0908456A2 (https=)
CA (1) CA2715550C (https=)
CL (1) CL2009000323A1 (https=)
CO (1) CO6251260A2 (https=)
CY (1) CY1114298T1 (https=)
DK (1) DK2242750T3 (https=)
EA (1) EA020511B1 (https=)
ES (1) ES2415208T3 (https=)
HR (1) HRP20130421T1 (https=)
IL (1) IL207258A0 (https=)
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NZ (1) NZ586990A (https=)
PE (1) PE20091575A1 (https=)
PL (1) PL2242750T3 (https=)
PT (1) PT2242750E (https=)
SI (1) SI2242750T1 (https=)
TW (1) TWI423798B (https=)
WO (1) WO2009102568A1 (https=)
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