KR101596229B1 - 식물에 있어서 이종유래 단백질의 발현 향상을 위하여 5'(5'-ｕｔｒ) 내에 최적화된 리더 작용기를 가진 인공 ｄｎａ 서열 - Google Patents

식물에 있어서 이종유래 단백질의 발현 향상을 위하여 5'(5'-ｕｔｒ) 내에 최적화된 리더 작용기를 가진 인공 ｄｎａ 서열 Download PDF

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KR101596229B1
KR101596229B1 KR1020097015452A KR20097015452A KR101596229B1 KR 101596229 B1 KR101596229 B1 KR 101596229B1 KR 1020097015452 A KR1020097015452 A KR 1020097015452A KR 20097015452 A KR20097015452 A KR 20097015452A KR 101596229 B1 KR101596229 B1 KR 101596229B1
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artificial dna
sequence
artificial
promoter
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KR20090102825A (ko
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마르체티 스테파노
디 아미시스 프란체스카
파티 타마라
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로디나 홀딩 에스아
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
    • A01H6/4636—Oryza sp. [rice]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease

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  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Environmental Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Physiology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020097015452A 2006-12-29 2007-12-27 식물에 있어서 이종유래 단백질의 발현 향상을 위하여 5'(5'-ｕｔｒ) 내에 최적화된 리더 작용기를 가진 인공 ｄｎａ 서열 Expired - Fee Related KR101596229B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUD2006A000280 2006-12-29
IT000280A ITUD20060280A1 (it) 2006-12-29 2006-12-29 Sequenza artificiale di dna evente funzione di leader in 5' (5'-utr) ottimizzata per la sovraespressione di proteine eterologhe in pianta

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KR20090102825A KR20090102825A (ko) 2009-09-30
KR101596229B1 true KR101596229B1 (ko) 2016-03-07

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KR1020097015452A Expired - Fee Related KR101596229B1 (ko) 2006-12-29 2007-12-27 식물에 있어서 이종유래 단백질의 발현 향상을 위하여 5'(5'-ｕｔｒ) 내에 최적화된 리더 작용기를 가진 인공 ｄｎａ 서열

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Country Link
US (1) US9085775B2 (enExample)
EP (1) EP2118291B1 (enExample)
JP (2) JP2010514432A (enExample)
KR (1) KR101596229B1 (enExample)
CN (1) CN101617048B (enExample)
AU (1) AU2007341217A1 (enExample)
BR (1) BRPI0720641A8 (enExample)
CA (1) CA2674170C (enExample)
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ES (1) ES2546184T3 (enExample)
HU (1) HUE027484T2 (enExample)
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NZ (1) NZ578518A (enExample)
PL (1) PL2118291T3 (enExample)
PT (1) PT2118291E (enExample)
RU (1) RU2009129091A (enExample)
WO (1) WO2008080954A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITUD20080055A1 (it) * 2008-03-13 2009-09-14 Transactiva S R L Procedimento per la produzione di una proteina umana in pianta, in particolare un enzima lisosomiale umano ricombinante in endosperma di cereali
KR101703540B1 (ko) * 2012-06-04 2017-02-08 대한민국 3'' 영역의 염기 변이를 통한 전체 단백질의 발현 조절 방법
ITUD20130002A1 (it) * 2013-01-16 2014-07-17 Transactiva S R L Sequenza artificiale di dna avente funzione di leader in 5' (5'-utr) ottimizzata per la sovraespressione di proteine ricombinanti in pianta e metodo per la produzione di proteine ricombinanti in pianta
JP6609551B2 (ja) * 2013-06-25 2019-11-20 ザ ユニバーシティー オブ ユタ リサーチ ファンデーション ポリメラーゼ連鎖反応を行う方法及びその関連する使用
IT201700042052A1 (it) * 2017-04-14 2018-10-14 Transactiva S R L Vettore di espressione e metodo per la produzione di una proteina umana in pianta, in particolare un anticorpo ricombinante in endosperma di cereale
CN121022840A (zh) * 2025-02-06 2025-11-28 北京臻知医学科技有限责任公司 一种5’UTR序列及其在提高mRNA翻译效率中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999031258A1 (en) * 1997-12-12 1999-06-24 Mogen International N.V. Constitutive plant promoters

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8613481D0 (en) * 1986-06-04 1986-07-09 Diatech Ltd Translation of mrna
GB9206016D0 (en) * 1992-03-19 1992-04-29 Sandoz Ltd Improvements in or relating to organic compounds
US5362865A (en) 1993-09-02 1994-11-08 Monsanto Company Enhanced expression in plants using non-translated leader sequences
GB9515941D0 (en) 1995-08-03 1995-10-04 Zeneca Ltd DNA constructs
JP3761628B2 (ja) * 1995-07-14 2006-03-29 住友化学株式会社 植物プロモーターおよびその利用
GB9516241D0 (en) 1995-08-08 1995-10-11 Zeneca Ltd Dna constructs
US6376747B1 (en) 1999-08-27 2002-04-23 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada Plant-derived map kinase kinase
FR2815969B1 (fr) * 2000-10-30 2004-12-10 Aventis Cropscience Sa Plantes tolerantes aux herbicides par contournement de voie metabolique
KR100474115B1 (ko) * 2001-06-01 2005-03-08 대한민국 유전자변형식물에 대한 ｐｃｒ 검정용 프라이머
US7847064B2 (en) * 2004-07-09 2010-12-07 Donald Danforth Plant Science Center Methods and compositions for regulating gene expression in plant cells
US7517689B2 (en) * 2004-07-09 2009-04-14 Donald Danforth Plant Science Center Methods and compositions for regulating gene expression in plant cells
US8065093B2 (en) * 2004-10-06 2011-11-22 Agency For Science, Technology, And Research Methods, systems, and compositions for classification, prognosis, and diagnosis of cancers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999031258A1 (en) * 1997-12-12 1999-06-24 Mogen International N.V. Constitutive plant promoters

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Publication number Publication date
CN101617048A (zh) 2009-12-30
JP5913434B2 (ja) 2016-04-27
JP2010514432A (ja) 2010-05-06
CA2674170C (en) 2019-03-12
BRPI0720641A8 (pt) 2017-12-19
US20110041222A1 (en) 2011-02-17
ES2546184T3 (es) 2015-09-21
CA2674170A1 (en) 2008-07-10
PT2118291E (pt) 2015-09-24
HUE027484T2 (en) 2016-09-28
WO2008080954A1 (en) 2008-07-10
PL2118291T3 (pl) 2015-11-30
EP2118291A1 (en) 2009-11-18
DK2118291T3 (en) 2015-08-31
CY1116649T1 (el) 2017-03-15
CN101617048B (zh) 2012-11-07
EP2118291B1 (en) 2015-06-03
US9085775B2 (en) 2015-07-21
KR20090102825A (ko) 2009-09-30
AU2007341217A1 (en) 2008-07-10
JP2014221040A (ja) 2014-11-27
BRPI0720641A2 (pt) 2014-03-18
NZ578518A (en) 2012-08-31
RU2009129091A (ru) 2011-02-10
ITUD20060280A1 (it) 2008-06-30

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