HUE027484T2 - 5'-end optimized conductive (5'-UTR) artificial DNA sequence for improved expression of heterologous proteins in plants - Google Patents

5'-end optimized conductive (5'-UTR) artificial DNA sequence for improved expression of heterologous proteins in plants Download PDF

Info

Publication number
HUE027484T2
HUE027484T2 HUE07858186A HUE07858186A HUE027484T2 HU E027484 T2 HUE027484 T2 HU E027484T2 HU E07858186 A HUE07858186 A HU E07858186A HU E07858186 A HUE07858186 A HU E07858186A HU E027484 T2 HUE027484 T2 HU E027484T2
Authority
HU
Hungary
Prior art keywords
amely amely
tartalmaz tartalmaz
artificial
egyetlen
promoter
Prior art date
Application number
HUE07858186A
Other languages
English (en)
Hungarian (hu)
Inventor
Stefano Marchetti
Amicis Francesca De
Tamara Patti
Original Assignee
Rodina Holding S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rodina Holding S A filed Critical Rodina Holding S A
Publication of HUE027484T2 publication Critical patent/HUE027484T2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
    • A01H6/4636—Oryza sp. [rice]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Environmental Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Physiology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HUE07858186A 2006-12-29 2007-12-27 5'-end optimized conductive (5'-UTR) artificial DNA sequence for improved expression of heterologous proteins in plants HUE027484T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000280A ITUD20060280A1 (it) 2006-12-29 2006-12-29 Sequenza artificiale di dna evente funzione di leader in 5' (5'-utr) ottimizzata per la sovraespressione di proteine eterologhe in pianta

Publications (1)

Publication Number Publication Date
HUE027484T2 true HUE027484T2 (en) 2016-09-28

Family

ID=39205172

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE07858186A HUE027484T2 (en) 2006-12-29 2007-12-27 5'-end optimized conductive (5'-UTR) artificial DNA sequence for improved expression of heterologous proteins in plants

Country Status (18)

Country Link
US (1) US9085775B2 (enExample)
EP (1) EP2118291B1 (enExample)
JP (2) JP2010514432A (enExample)
KR (1) KR101596229B1 (enExample)
CN (1) CN101617048B (enExample)
AU (1) AU2007341217A1 (enExample)
BR (1) BRPI0720641A8 (enExample)
CA (1) CA2674170C (enExample)
CY (1) CY1116649T1 (enExample)
DK (1) DK2118291T3 (enExample)
ES (1) ES2546184T3 (enExample)
HU (1) HUE027484T2 (enExample)
IT (1) ITUD20060280A1 (enExample)
NZ (1) NZ578518A (enExample)
PL (1) PL2118291T3 (enExample)
PT (1) PT2118291E (enExample)
RU (1) RU2009129091A (enExample)
WO (1) WO2008080954A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITUD20080055A1 (it) * 2008-03-13 2009-09-14 Transactiva S R L Procedimento per la produzione di una proteina umana in pianta, in particolare un enzima lisosomiale umano ricombinante in endosperma di cereali
KR101703540B1 (ko) * 2012-06-04 2017-02-08 대한민국 3'' 영역의 염기 변이를 통한 전체 단백질의 발현 조절 방법
ITUD20130002A1 (it) * 2013-01-16 2014-07-17 Transactiva S R L Sequenza artificiale di dna avente funzione di leader in 5' (5'-utr) ottimizzata per la sovraespressione di proteine ricombinanti in pianta e metodo per la produzione di proteine ricombinanti in pianta
JP6609551B2 (ja) * 2013-06-25 2019-11-20 ザ ユニバーシティー オブ ユタ リサーチ ファンデーション ポリメラーゼ連鎖反応を行う方法及びその関連する使用
IT201700042052A1 (it) * 2017-04-14 2018-10-14 Transactiva S R L Vettore di espressione e metodo per la produzione di una proteina umana in pianta, in particolare un anticorpo ricombinante in endosperma di cereale
CN121022840A (zh) * 2025-02-06 2025-11-28 北京臻知医学科技有限责任公司 一种5’UTR序列及其在提高mRNA翻译效率中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8613481D0 (en) * 1986-06-04 1986-07-09 Diatech Ltd Translation of mrna
GB9206016D0 (en) * 1992-03-19 1992-04-29 Sandoz Ltd Improvements in or relating to organic compounds
US5362865A (en) 1993-09-02 1994-11-08 Monsanto Company Enhanced expression in plants using non-translated leader sequences
GB9515941D0 (en) 1995-08-03 1995-10-04 Zeneca Ltd DNA constructs
JP3761628B2 (ja) * 1995-07-14 2006-03-29 住友化学株式会社 植物プロモーターおよびその利用
GB9516241D0 (en) 1995-08-08 1995-10-11 Zeneca Ltd Dna constructs
ZA9811228B (en) * 1997-12-12 1999-06-14 Mogen Int New constitutive plant promoters
US6376747B1 (en) 1999-08-27 2002-04-23 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada Plant-derived map kinase kinase
FR2815969B1 (fr) * 2000-10-30 2004-12-10 Aventis Cropscience Sa Plantes tolerantes aux herbicides par contournement de voie metabolique
KR100474115B1 (ko) * 2001-06-01 2005-03-08 대한민국 유전자변형식물에 대한 ｐｃｒ 검정용 프라이머
US7847064B2 (en) * 2004-07-09 2010-12-07 Donald Danforth Plant Science Center Methods and compositions for regulating gene expression in plant cells
US7517689B2 (en) * 2004-07-09 2009-04-14 Donald Danforth Plant Science Center Methods and compositions for regulating gene expression in plant cells
US8065093B2 (en) * 2004-10-06 2011-11-22 Agency For Science, Technology, And Research Methods, systems, and compositions for classification, prognosis, and diagnosis of cancers

Also Published As

Publication number Publication date
CN101617048A (zh) 2009-12-30
JP5913434B2 (ja) 2016-04-27
JP2010514432A (ja) 2010-05-06
CA2674170C (en) 2019-03-12
BRPI0720641A8 (pt) 2017-12-19
US20110041222A1 (en) 2011-02-17
ES2546184T3 (es) 2015-09-21
CA2674170A1 (en) 2008-07-10
PT2118291E (pt) 2015-09-24
KR101596229B1 (ko) 2016-03-07
WO2008080954A1 (en) 2008-07-10
PL2118291T3 (pl) 2015-11-30
EP2118291A1 (en) 2009-11-18
DK2118291T3 (en) 2015-08-31
CY1116649T1 (el) 2017-03-15
CN101617048B (zh) 2012-11-07
EP2118291B1 (en) 2015-06-03
US9085775B2 (en) 2015-07-21
KR20090102825A (ko) 2009-09-30
AU2007341217A1 (en) 2008-07-10
JP2014221040A (ja) 2014-11-27
BRPI0720641A2 (pt) 2014-03-18
NZ578518A (en) 2012-08-31
RU2009129091A (ru) 2011-02-10
ITUD20060280A1 (it) 2008-06-30

Similar Documents

Publication Publication Date Title
DE69928264T2 (de) Samen-bevorzugende promotoren
JP5655947B2 (ja) 成葉特異的プロモーター
DE112010003500T5 (de) Regulatorische Nukleinsäuremoleküle für die Verstärkung der konstitutiven Genexpression in Pflanzen
DE112010003493T5 (de) Regulatorische Nukleinsäuremoleküle für die Verstärkung der samenspeziflschen und/oder samenpräferentielen Genexpression in Pflanzen
HUE027484T2 (en) 5'-end optimized conductive (5'-UTR) artificial DNA sequence for improved expression of heterologous proteins in plants
JPH0231683A (ja) Ｔ‐ｄｎａ７８０遺伝子の転写活性化要素
CN115820721B (zh) 提高贵州优质特色稻大白果糯分蘖和产量的方法和一种启动子核心序列及应用
CN114231539A (zh) 柳枝稷SBP-box类转录因子PvSPL6的应用及其重组载体
US20050235382A1 (en) Plant regulatory sequences for selective control of gene expression
US20090307797A1 (en) Seed-Preferred Regulatory Elements
CN105567687B (zh) 一种花生种子特异启动子ahssp1及其应用
US20150284738A1 (en) Artificial dna sequence with optimized leader function in 5' (5'-utr) for the improved expression of heterologous proteins in plants
JP2014003917A (ja) サトウキビ花成制御技術
TWI480375B (zh) 中草藥糖基轉移酶啟動子的表現調控與應用
JP5472089B2 (ja) 光合成組織における遺伝子発現制御に関わるｄｎａ
CN114214332A (zh) 一种天目地黄花青素相关基因RcMYB1及其应用
CN112010954A (zh) 茶树phr1转录因子及其编码基因和应用
CA2883151C (en) Stress-inducible promoter and uses thereof
CN112724216B (zh) 改变玉米开花期的基因及方法
CN111448206B (zh) 源自番薯的IbOr-R96H变异体及其用途
CN104797712A (zh) 提高棉纤维长度的方法
JP2775405B2 (ja) 新規チオニン
KR101700103B1 (ko) 감귤 유래의 ＣｕＣＲＴＩＳＯ 프로모터 및 이의 용도
CN106086038A (zh) 一种青蒿wrky类转录因子编码序列及克隆方法与应用
US20050102711A1 (en) Banana actin gene and its promoter