JP2010514432A - 植物における異種タンパク質の改善された発現のための、5’(5’−utr)における最適化されたリーダー機能を有する人工dna配列 - Google Patents

植物における異種タンパク質の改善された発現のための、5’(5’−utr)における最適化されたリーダー機能を有する人工dna配列 Download PDF

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JP2010514432A
JP2010514432A JP2009543473A JP2009543473A JP2010514432A JP 2010514432 A JP2010514432 A JP 2010514432A JP 2009543473 A JP2009543473 A JP 2009543473A JP 2009543473 A JP2009543473 A JP 2009543473A JP 2010514432 A JP2010514432 A JP 2010514432A
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sequence according
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マルケッティ,ステファノ
デ・アミチス,フランチェスカ
パッティ,タマラ
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ウニヴェルシータ・デッリ・ストゥーディ・ディ・ウーディネ
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00Processes for modifying genotypes ; Plants characterised by associated natural traits
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/46Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
    • A01H6/4636Oryza sp. [rice]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Natural Medicines & Medicinal Plants (AREA)
  • Physiology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2009543473A 2006-12-29 2007-12-27 植物における異種タンパク質の改善された発現のための、5’(5’−utr)における最適化されたリーダー機能を有する人工dna配列 Pending JP2010514432A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000280A ITUD20060280A1 (it) 2006-12-29 2006-12-29 Sequenza artificiale di dna evente funzione di leader in 5' (5'-utr) ottimizzata per la sovraespressione di proteine eterologhe in pianta
PCT/EP2007/064590 WO2008080954A1 (en) 2006-12-29 2007-12-27 Artificial dna sequence with optimized leader function in 5' (5'-utr) for the improved expression of heterologous proteins in plants

Related Child Applications (1)

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JP2014105535A Division JP5913434B2 (ja) 2006-12-29 2014-05-21 植物における異種タンパク質の改善された発現のための、5’(5’−utr)における最適化されたリーダー機能を有する人工dna配列

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JP2010514432A true JP2010514432A (ja) 2010-05-06
JP2010514432A5 JP2010514432A5 (enExample) 2011-02-17

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JP2009543473A Pending JP2010514432A (ja) 2006-12-29 2007-12-27 植物における異種タンパク質の改善された発現のための、5’(5’−utr)における最適化されたリーダー機能を有する人工dna配列
JP2014105535A Active JP5913434B2 (ja) 2006-12-29 2014-05-21 植物における異種タンパク質の改善された発現のための、5’(5’−utr)における最適化されたリーダー機能を有する人工dna配列

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US (1) US9085775B2 (enExample)
EP (1) EP2118291B1 (enExample)
JP (2) JP2010514432A (enExample)
KR (1) KR101596229B1 (enExample)
CN (1) CN101617048B (enExample)
AU (1) AU2007341217A1 (enExample)
BR (1) BRPI0720641A8 (enExample)
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NZ (1) NZ578518A (enExample)
PL (1) PL2118291T3 (enExample)
PT (1) PT2118291E (enExample)
RU (1) RU2009129091A (enExample)
WO (1) WO2008080954A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016502864A (ja) * 2013-01-16 2016-02-01 ロディナ ホールディング ソシエタ アノニマ 植物における組換えタンパク質の過剰発現のための5’(5’−utr)に最適化されたリーダー機能を持つ人工dna配列と植物における組換えタンパク質の産生方法

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Publication number Priority date Publication date Assignee Title
ITUD20080055A1 (it) * 2008-03-13 2009-09-14 Transactiva S R L Procedimento per la produzione di una proteina umana in pianta, in particolare un enzima lisosomiale umano ricombinante in endosperma di cereali
KR101703540B1 (ko) * 2012-06-04 2017-02-08 대한민국 3'' 영역의 염기 변이를 통한 전체 단백질의 발현 조절 방법
JP6609551B2 (ja) * 2013-06-25 2019-11-20 ザ ユニバーシティー オブ ユタ リサーチ ファンデーション ポリメラーゼ連鎖反応を行う方法及びその関連する使用
IT201700042052A1 (it) * 2017-04-14 2018-10-14 Transactiva S R L Vettore di espressione e metodo per la produzione di una proteina umana in pianta, in particolare un anticorpo ricombinante in endosperma di cereale
CN121022840A (zh) * 2025-02-06 2025-11-28 北京臻知医学科技有限责任公司 一种5’UTR序列及其在提高mRNA翻译效率中的应用

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GB8613481D0 (en) * 1986-06-04 1986-07-09 Diatech Ltd Translation of mrna
GB9206016D0 (en) * 1992-03-19 1992-04-29 Sandoz Ltd Improvements in or relating to organic compounds
US5362865A (en) 1993-09-02 1994-11-08 Monsanto Company Enhanced expression in plants using non-translated leader sequences
GB9515941D0 (en) 1995-08-03 1995-10-04 Zeneca Ltd DNA constructs
JP3761628B2 (ja) * 1995-07-14 2006-03-29 住友化学株式会社 植物プロモーターおよびその利用
GB9516241D0 (en) 1995-08-08 1995-10-11 Zeneca Ltd Dna constructs
ZA9811228B (en) * 1997-12-12 1999-06-14 Mogen Int New constitutive plant promoters
US6376747B1 (en) 1999-08-27 2002-04-23 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada Plant-derived map kinase kinase
FR2815969B1 (fr) * 2000-10-30 2004-12-10 Aventis Cropscience Sa Plantes tolerantes aux herbicides par contournement de voie metabolique
KR100474115B1 (ko) * 2001-06-01 2005-03-08 대한민국 유전자변형식물에 대한 pcr 검정용 프라이머
US7847064B2 (en) * 2004-07-09 2010-12-07 Donald Danforth Plant Science Center Methods and compositions for regulating gene expression in plant cells
US7517689B2 (en) * 2004-07-09 2009-04-14 Donald Danforth Plant Science Center Methods and compositions for regulating gene expression in plant cells
US8065093B2 (en) * 2004-10-06 2011-11-22 Agency For Science, Technology, And Research Methods, systems, and compositions for classification, prognosis, and diagnosis of cancers

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JPN5010000010; DOWSON DAY M J: PLANT MOLECULAR BIOLOGY V23 N1, 1993, P97-109, SPRINGER *
JPN6012058590; Journal of Virology Vol. 70(12), 1996, pp. 8411-8421 *
JPN6012058593; Proceedings of the National Academy of Sciences of the United States of America Vol. 86, 1989, pp. 129-132 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016502864A (ja) * 2013-01-16 2016-02-01 ロディナ ホールディング ソシエタ アノニマ 植物における組換えタンパク質の過剰発現のための5’(5’−utr)に最適化されたリーダー機能を持つ人工dna配列と植物における組換えタンパク質の産生方法

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CN101617048A (zh) 2009-12-30
JP5913434B2 (ja) 2016-04-27
CA2674170C (en) 2019-03-12
BRPI0720641A8 (pt) 2017-12-19
US20110041222A1 (en) 2011-02-17
ES2546184T3 (es) 2015-09-21
CA2674170A1 (en) 2008-07-10
PT2118291E (pt) 2015-09-24
HUE027484T2 (en) 2016-09-28
KR101596229B1 (ko) 2016-03-07
WO2008080954A1 (en) 2008-07-10
PL2118291T3 (pl) 2015-11-30
EP2118291A1 (en) 2009-11-18
DK2118291T3 (en) 2015-08-31
CY1116649T1 (el) 2017-03-15
CN101617048B (zh) 2012-11-07
EP2118291B1 (en) 2015-06-03
US9085775B2 (en) 2015-07-21
KR20090102825A (ko) 2009-09-30
AU2007341217A1 (en) 2008-07-10
JP2014221040A (ja) 2014-11-27
BRPI0720641A2 (pt) 2014-03-18
NZ578518A (en) 2012-08-31
RU2009129091A (ru) 2011-02-10
ITUD20060280A1 (it) 2008-06-30

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