KR101585705B1 - 활성 성분 그래뉼의 새로운 제조 방법 및 그로부터 수득되는 그래뉼 - Google Patents

활성 성분 그래뉼의 새로운 제조 방법 및 그로부터 수득되는 그래뉼 Download PDF

Info

Publication number
KR101585705B1
KR101585705B1 KR1020117013588A KR20117013588A KR101585705B1 KR 101585705 B1 KR101585705 B1 KR 101585705B1 KR 1020117013588 A KR1020117013588 A KR 1020117013588A KR 20117013588 A KR20117013588 A KR 20117013588A KR 101585705 B1 KR101585705 B1 KR 101585705B1
Authority
KR
South Korea
Prior art keywords
granules
active ingredients
present
support
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020117013588A
Other languages
English (en)
Korean (ko)
Other versions
KR20110095888A (ko
Inventor
크리스토프 르봉
파스칼 서플리
Original Assignee
데브레게아 에 아쏘시에 파르마
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40348849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101585705(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 데브레게아 에 아쏘시에 파르마 filed Critical 데브레게아 에 아쏘시에 파르마
Publication of KR20110095888A publication Critical patent/KR20110095888A/ko
Application granted granted Critical
Publication of KR101585705B1 publication Critical patent/KR101585705B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fertilizers (AREA)
  • Glanulating (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Seasonings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020117013588A 2008-11-14 2009-11-13 활성 성분 그래뉼의 새로운 제조 방법 및 그로부터 수득되는 그래뉼 Expired - Fee Related KR101585705B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0857764 2008-11-14
FR0857764A FR2938432B1 (fr) 2008-11-14 2008-11-14 Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus

Publications (2)

Publication Number Publication Date
KR20110095888A KR20110095888A (ko) 2011-08-25
KR101585705B1 true KR101585705B1 (ko) 2016-01-15

Family

ID=40348849

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117013588A Expired - Fee Related KR101585705B1 (ko) 2008-11-14 2009-11-13 활성 성분 그래뉼의 새로운 제조 방법 및 그로부터 수득되는 그래뉼

Country Status (25)

Country Link
US (1) US20110280945A1 (enExample)
EP (1) EP2349226A1 (enExample)
JP (1) JP5608681B2 (enExample)
KR (1) KR101585705B1 (enExample)
CN (1) CN102223879A (enExample)
AR (1) AR074330A1 (enExample)
AU (1) AU2009315449B2 (enExample)
BR (1) BRPI0916019A2 (enExample)
CA (1) CA2743753A1 (enExample)
CL (1) CL2011001115A1 (enExample)
CO (1) CO6382108A2 (enExample)
CU (1) CU20110107A7 (enExample)
EA (1) EA201100757A1 (enExample)
FR (1) FR2938432B1 (enExample)
IL (1) IL212850A0 (enExample)
MA (1) MA32789B1 (enExample)
MX (1) MX2011005072A (enExample)
NZ (1) NZ592857A (enExample)
PE (1) PE20110945A1 (enExample)
SG (1) SG195651A1 (enExample)
TN (1) TN2011000235A1 (enExample)
TW (1) TWI522113B (enExample)
UA (1) UA103781C2 (enExample)
WO (1) WO2010055268A1 (enExample)
ZA (1) ZA201103543B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2971422B1 (fr) * 2011-02-11 2016-05-20 Debregeas Et Associes Pharma Granules d'acide gamma-hydroxybutyrique
US20140127296A1 (en) * 2012-11-05 2014-05-08 Kenneth John Tibbs Pharmaceutical preparation and method for treatment of diabetes
US9241956B2 (en) * 2012-11-05 2016-01-26 Kenneth John Tibbs Pharmaceutical preparation and method for treatment of diabetes
US11058635B1 (en) * 2020-10-15 2021-07-13 King Abdulaziz University Oral administration of 5-FU in a gelling nanosuspension for targeted delivery to treat colorectal cancers
KR20240157168A (ko) * 2023-04-24 2024-11-01 주식회사 케이티앤지 바인더를 사용하는 파우치 충진 물질의 제조 방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6327424A (ja) * 1986-07-17 1988-02-05 Shionogi & Co Ltd 徐放性製剤およびその製造法
JP2820829B2 (ja) * 1991-03-07 1998-11-05 武田薬品工業株式会社 有核散剤およびその製造方法
JPH08310969A (ja) * 1995-05-22 1996-11-26 Lion Corp 固形薬品組成物及びその製造方法
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
PT1178778E (pt) * 1999-05-17 2006-06-30 D B F Granulos que contem uma substancia vegetal e o seu procedimento de preparacao
MY148805A (en) * 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
US9247765B2 (en) * 2004-01-14 2016-02-02 Omniactive Health Technologies Limited Stable beadlets of lipophilic nutrients
FR2880541B1 (fr) * 2005-01-10 2008-02-22 Amalric Veret Une nouvelle formule de plantes sous forme de micro-granules de xilitol pour renforcer les effets des plantes et leurs proprietes par une meilleure assimilation
US20060182796A1 (en) * 2005-02-03 2006-08-17 Abrika Pharmaceuticals, Inc. Taste masked pharmaceutical compositions
KR101468053B1 (ko) * 2006-08-31 2014-12-02 앱탈리스 파마테크, 인코포레이티드 약 염기성 약물의 고용체를 포함하는 약물 전달 시스템
EP2110413B1 (en) * 2007-02-14 2013-03-20 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Dispersing agent for organic pigment and use thereof
US20090004281A1 (en) * 2007-06-26 2009-01-01 Biovail Laboratories International S.R.L. Multiparticulate osmotic delivery system

Also Published As

Publication number Publication date
CO6382108A2 (es) 2012-02-15
CU20110107A7 (es) 2012-01-31
EA201100757A1 (ru) 2011-12-30
NZ592857A (en) 2013-07-26
CN102223879A (zh) 2011-10-19
ZA201103543B (en) 2012-01-25
BRPI0916019A2 (pt) 2015-11-10
CL2011001115A1 (es) 2011-11-11
CA2743753A1 (fr) 2010-05-20
TWI522113B (zh) 2016-02-21
AU2009315449B2 (en) 2015-03-26
UA103781C2 (uk) 2013-11-25
EP2349226A1 (fr) 2011-08-03
FR2938432B1 (fr) 2011-05-20
SG195651A1 (en) 2013-12-30
JP2012508786A (ja) 2012-04-12
AR074330A1 (es) 2011-01-05
MA32789B1 (fr) 2011-11-01
US20110280945A1 (en) 2011-11-17
TW201029667A (en) 2010-08-16
PE20110945A1 (es) 2012-02-01
JP5608681B2 (ja) 2014-10-15
AU2009315449A1 (en) 2010-05-20
IL212850A0 (en) 2011-07-31
WO2010055268A1 (fr) 2010-05-20
MX2011005072A (es) 2011-10-03
TN2011000235A1 (fr) 2012-12-17
KR20110095888A (ko) 2011-08-25
FR2938432A1 (fr) 2010-05-21

Similar Documents

Publication Publication Date Title
KR101563390B1 (ko) 감마-하이드록시부티르산을 주성분으로 하는 신규 조성물
KR101190708B1 (ko) 모사프리드 또는 이의 염을 포함하는 서방형 약학 조성물
EP1231903B1 (en) Coating of tablet cores
KR101585705B1 (ko) 활성 성분 그래뉼의 새로운 제조 방법 및 그로부터 수득되는 그래뉼
EP3981390B1 (en) Lacosamide pharmaceutical composition and pharmaceutical preparation thereof
EA021501B1 (ru) Гранулы липоевой кислоты
CN103648485A (zh) 罗苏伐他汀钙的药物组合物
CN103976997A (zh) 一种降血糖复方缓释胶囊及其制备方法
CN101601663A (zh) 左乙拉西坦的多单元缓释制剂及其制备方法
CN103239719A (zh) 二甲双胍复方药物组合物及其制备方法
KR101409330B1 (ko) 복용순응도가 향상된 서방성 당뇨병 치료용 복합제제 및 이의 제조방법
CN115813866B (zh) 一种枸橼酸西地那非口崩片及其生产制备方法
CN102552190A (zh) 一种艾普拉唑肠溶片剂及其制备方法
CN102824316B (zh) 埃索美拉唑含药微丸及其制备方法
EP4265242B1 (en) High dose tranexamic acid composition and process for preparation thereof
CA3163378A1 (en) Dosage form with sustained release melatonin pellets
CN101879139A (zh) 一种治疗消化性疾病的肠溶制剂及其制备方法
US8252312B1 (en) Oral solid composition comprising a lipid absorption inhibitor
DE102021119130A1 (de) Ethylcellulose-beschichtete Partikel enthaltend ein Salz aus Tapentadol und Phosphorsäure
CN108066304A (zh) 具有缓释性能的坦索罗辛口腔崩解片组合物
CN103040761A (zh) 一种新的盐酸二甲双胍缓释小丸及其制备方法
CN112315942B (zh) 一种盐酸曲美他嗪缓释制剂及其制备方法
EP2736496B1 (en) Pharmaceutical composition containing an antimuscarinic agent and method for the preparation thereof
CN112057429A (zh) 雷西纳德控释药物组合物
CN120815048A (zh) 一种达格列净二甲双胍缓释片剂及其制备方法

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

A302 Request for accelerated examination
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0302 Request for accelerated examination

St.27 status event code: A-1-2-D10-D17-exm-PA0302

St.27 status event code: A-1-2-D10-D16-exm-PA0302

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20190103

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20200109

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20200109