FR2938432B1 - Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus - Google Patents

Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus

Info

Publication number
FR2938432B1
FR2938432B1 FR0857764A FR0857764A FR2938432B1 FR 2938432 B1 FR2938432 B1 FR 2938432B1 FR 0857764 A FR0857764 A FR 0857764A FR 0857764 A FR0857764 A FR 0857764A FR 2938432 B1 FR2938432 B1 FR 2938432B1
Authority
FR
France
Prior art keywords
granules
active ingredients
novel process
preparing pellets
pellets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0857764A
Other languages
English (en)
French (fr)
Other versions
FR2938432A1 (fr
Inventor
Christophe Lebon
Pascal Suplie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Debregeas Et Associes Pharma SAS
Original Assignee
Debregeas Et Associes Pharma SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40348849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2938432(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Debregeas Et Associes Pharma SAS filed Critical Debregeas Et Associes Pharma SAS
Priority to FR0857764A priority Critical patent/FR2938432B1/fr
Priority to US13/129,028 priority patent/US20110280945A1/en
Priority to BRPI0916019A priority patent/BRPI0916019A2/pt
Priority to CN2009801457596A priority patent/CN102223879A/zh
Priority to ARP090104388A priority patent/AR074330A1/es
Priority to NZ592857A priority patent/NZ592857A/xx
Priority to AU2009315449A priority patent/AU2009315449B2/en
Priority to EP09768187A priority patent/EP2349226A1/fr
Priority to SG2013082482A priority patent/SG195651A1/en
Priority to CA2743753A priority patent/CA2743753A1/fr
Priority to EA201100757A priority patent/EA201100757A1/ru
Priority to PCT/FR2009/052180 priority patent/WO2010055268A1/fr
Priority to PE2011001032A priority patent/PE20110945A1/es
Priority to MX2011005072A priority patent/MX2011005072A/es
Priority to JP2011543800A priority patent/JP5608681B2/ja
Priority to KR1020117013588A priority patent/KR101585705B1/ko
Priority to UAA201105988A priority patent/UA103781C2/uk
Priority to TW098138860A priority patent/TWI522113B/zh
Publication of FR2938432A1 publication Critical patent/FR2938432A1/fr
Priority to TN2011000235A priority patent/TN2011000235A1/fr
Priority to IL212850A priority patent/IL212850A0/en
Priority to ZA2011/03543A priority patent/ZA201103543B/en
Priority to CO11059023A priority patent/CO6382108A2/es
Priority to MA33837A priority patent/MA32789B1/fr
Priority to CL2011001115A priority patent/CL2011001115A1/es
Priority to CU20110107A priority patent/CU20110107A7/es
Publication of FR2938432B1 publication Critical patent/FR2938432B1/fr
Application granted granted Critical
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fertilizers (AREA)
  • Glanulating (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Seasonings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0857764A 2008-11-14 2008-11-14 Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus Expired - Fee Related FR2938432B1 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR0857764A FR2938432B1 (fr) 2008-11-14 2008-11-14 Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus
JP2011543800A JP5608681B2 (ja) 2008-11-14 2009-11-13 活性成分の粒状物質を製造する新規の方法、及びそれにより得られた粒状物質
KR1020117013588A KR101585705B1 (ko) 2008-11-14 2009-11-13 활성 성분 그래뉼의 새로운 제조 방법 및 그로부터 수득되는 그래뉼
CN2009801457596A CN102223879A (zh) 2008-11-14 2009-11-13 制备活性组分颗粒的新方法及所获得的颗粒
ARP090104388A AR074330A1 (es) 2008-11-14 2009-11-13 Nuevo procedimiento para la preparacion de granulos de principios activos y granulos asi obtenidos
NZ592857A NZ592857A (en) 2008-11-14 2009-11-13 Novel method for preparing granulates of active principles, and granulates obtained thereof
AU2009315449A AU2009315449B2 (en) 2008-11-14 2009-11-13 Novel method for preparing granulates of active principles, and granulates obtained thereof
EP09768187A EP2349226A1 (fr) 2008-11-14 2009-11-13 Nouveau procédé de préparation de granulés de principes actifs, et granulés tels qu'obtenus
SG2013082482A SG195651A1 (en) 2008-11-14 2009-11-13 Novel method for preparing granulates of active principles, and granulates obtained thereof
CA2743753A CA2743753A1 (fr) 2008-11-14 2009-11-13 Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus
BRPI0916019A BRPI0916019A2 (pt) 2008-11-14 2009-11-13 "processo de preparação de um granulado e granulado"
PCT/FR2009/052180 WO2010055268A1 (fr) 2008-11-14 2009-11-13 Nouveau procédé de préparation de granulés de principes actifs, et granulés tels qu'obtenus
PE2011001032A PE20110945A1 (es) 2008-11-14 2009-11-13 Nuevo procedimiento de preparacion de granulados de principios activos y granulados tal como se lo ha obtenido
MX2011005072A MX2011005072A (es) 2008-11-14 2009-11-13 Nuevo procedimiento de preparacion de granulados de principios activos, y granulados tal como se los ha obtenido.
US13/129,028 US20110280945A1 (en) 2008-11-14 2009-11-13 Novel method for the preparation of granulates of active constituents, and granulates as obtained
UAA201105988A UA103781C2 (uk) 2008-11-14 2009-11-13 Спосіб виготовлення гранульованого препарату активних інгредієнтів та гранульоваий препарат, одержаний таким способом
EA201100757A EA201100757A1 (ru) 2008-11-14 2009-11-13 Способ приготовления гранулята действующих веществ и полученный таким способом гранулят
TW098138860A TWI522113B (zh) 2008-11-14 2009-11-16 用以製備活性組份顆粒之新穎方法，及製得之顆粒
TN2011000235A TN2011000235A1 (fr) 2008-11-14 2011-05-12 Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus
IL212850A IL212850A0 (en) 2008-11-14 2011-05-12 Novel method for the preparation of granulates of active constituents, and granulates as obtained
ZA2011/03543A ZA201103543B (en) 2008-11-14 2011-05-13 Novel method for preparing granulates of active principles, and granulates obtained thereof
CU20110107A CU20110107A7 (es) 2008-11-14 2011-05-13 Nuevo procedimiento de preparación de granulados de principios activos, y granulados tal como se los ha obtenido
CO11059023A CO6382108A2 (es) 2008-11-14 2011-05-13 Nuevo procedimiento de preparacion de granulados de principios activos, y granulados tal como se los ha obtenido
MA33837A MA32789B1 (fr) 2008-11-14 2011-05-13 Nouveau procede de preparation de granules de principes actifs et granules tels qu'ostenus
CL2011001115A CL2011001115A1 (es) 2008-11-14 2011-05-13 Procedimiento de preparacion de granulado de al menos dos principios activos, que comprende una etapa de aplicacion por pulverizacion de dichos principios activos sobre un soporte particular solido, donde los principios activos no son extractos de plantas.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0857764A FR2938432B1 (fr) 2008-11-14 2008-11-14 Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus

Publications (2)

Publication Number Publication Date
FR2938432A1 FR2938432A1 (fr) 2010-05-21
FR2938432B1 true FR2938432B1 (fr) 2011-05-20

Family

ID=40348849

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0857764A Expired - Fee Related FR2938432B1 (fr) 2008-11-14 2008-11-14 Nouveau procede de preparation de granules de principes actifs, et granules tels qu'obtenus

Country Status (25)

Country Link
US (1) US20110280945A1 (enExample)
EP (1) EP2349226A1 (enExample)
JP (1) JP5608681B2 (enExample)
KR (1) KR101585705B1 (enExample)
CN (1) CN102223879A (enExample)
AR (1) AR074330A1 (enExample)
AU (1) AU2009315449B2 (enExample)
BR (1) BRPI0916019A2 (enExample)
CA (1) CA2743753A1 (enExample)
CL (1) CL2011001115A1 (enExample)
CO (1) CO6382108A2 (enExample)
CU (1) CU20110107A7 (enExample)
EA (1) EA201100757A1 (enExample)
FR (1) FR2938432B1 (enExample)
IL (1) IL212850A0 (enExample)
MA (1) MA32789B1 (enExample)
MX (1) MX2011005072A (enExample)
NZ (1) NZ592857A (enExample)
PE (1) PE20110945A1 (enExample)
SG (1) SG195651A1 (enExample)
TN (1) TN2011000235A1 (enExample)
TW (1) TWI522113B (enExample)
UA (1) UA103781C2 (enExample)
WO (1) WO2010055268A1 (enExample)
ZA (1) ZA201103543B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2971422B1 (fr) * 2011-02-11 2016-05-20 Debregeas Et Associes Pharma Granules d'acide gamma-hydroxybutyrique
US20140127296A1 (en) * 2012-11-05 2014-05-08 Kenneth John Tibbs Pharmaceutical preparation and method for treatment of diabetes
US9241956B2 (en) * 2012-11-05 2016-01-26 Kenneth John Tibbs Pharmaceutical preparation and method for treatment of diabetes
US11058635B1 (en) * 2020-10-15 2021-07-13 King Abdulaziz University Oral administration of 5-FU in a gelling nanosuspension for targeted delivery to treat colorectal cancers
KR20240157168A (ko) * 2023-04-24 2024-11-01 주식회사 케이티앤지 바인더를 사용하는 파우치 충진 물질의 제조 방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6327424A (ja) * 1986-07-17 1988-02-05 Shionogi & Co Ltd 徐放性製剤およびその製造法
JP2820829B2 (ja) * 1991-03-07 1998-11-05 武田薬品工業株式会社 有核散剤およびその製造方法
JPH08310969A (ja) * 1995-05-22 1996-11-26 Lion Corp 固形薬品組成物及びその製造方法
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
PT1178778E (pt) * 1999-05-17 2006-06-30 D B F Granulos que contem uma substancia vegetal e o seu procedimento de preparacao
MY148805A (en) * 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
US9247765B2 (en) * 2004-01-14 2016-02-02 Omniactive Health Technologies Limited Stable beadlets of lipophilic nutrients
FR2880541B1 (fr) * 2005-01-10 2008-02-22 Amalric Veret Une nouvelle formule de plantes sous forme de micro-granules de xilitol pour renforcer les effets des plantes et leurs proprietes par une meilleure assimilation
US20060182796A1 (en) * 2005-02-03 2006-08-17 Abrika Pharmaceuticals, Inc. Taste masked pharmaceutical compositions
KR101468053B1 (ko) * 2006-08-31 2014-12-02 앱탈리스 파마테크, 인코포레이티드 약 염기성 약물의 고용체를 포함하는 약물 전달 시스템
EP2110413B1 (en) * 2007-02-14 2013-03-20 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Dispersing agent for organic pigment and use thereof
US20090004281A1 (en) * 2007-06-26 2009-01-01 Biovail Laboratories International S.R.L. Multiparticulate osmotic delivery system

Also Published As

Publication number Publication date
CO6382108A2 (es) 2012-02-15
CU20110107A7 (es) 2012-01-31
EA201100757A1 (ru) 2011-12-30
NZ592857A (en) 2013-07-26
CN102223879A (zh) 2011-10-19
ZA201103543B (en) 2012-01-25
BRPI0916019A2 (pt) 2015-11-10
CL2011001115A1 (es) 2011-11-11
CA2743753A1 (fr) 2010-05-20
TWI522113B (zh) 2016-02-21
AU2009315449B2 (en) 2015-03-26
UA103781C2 (uk) 2013-11-25
EP2349226A1 (fr) 2011-08-03
SG195651A1 (en) 2013-12-30
JP2012508786A (ja) 2012-04-12
AR074330A1 (es) 2011-01-05
MA32789B1 (fr) 2011-11-01
US20110280945A1 (en) 2011-11-17
TW201029667A (en) 2010-08-16
PE20110945A1 (es) 2012-02-01
JP5608681B2 (ja) 2014-10-15
AU2009315449A1 (en) 2010-05-20
IL212850A0 (en) 2011-07-31
KR101585705B1 (ko) 2016-01-15
WO2010055268A1 (fr) 2010-05-20
MX2011005072A (es) 2011-10-03
TN2011000235A1 (fr) 2012-12-17
KR20110095888A (ko) 2011-08-25
FR2938432A1 (fr) 2010-05-21

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