KR101419320B1 - 2-(치환된-아미노)-벤조티아졸 설폰아미드 ｈｉｖ 프로테아제 저해제 - Google Patents

2-(치환된-아미노)-벤조티아졸 설폰아미드 ｈｉｖ 프로테아제 저해제 Download PDF

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KR101419320B1
KR101419320B1 KR1020097000754A KR20097000754A KR101419320B1 KR 101419320 B1 KR101419320 B1 KR 101419320B1 KR 1020097000754 A KR1020097000754 A KR 1020097000754A KR 20097000754 A KR20097000754 A KR 20097000754A KR 101419320 B1 KR101419320 B1 KR 101419320B1
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South Korea
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compound
compounds
formula
alkyl
hiv
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Korean (ko)
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KR20090024257A (ko
Inventor
코크 허만 데
팀 휴고 마리아 욘커스
파울 요제프 가브리엘 마리아 보오난츠
스테판 율리엔 라스트
인게 디린크
유디쓰 에바 바우마이스터
클로오스터 게르벤 알베르트 엘로이테리우스 반트
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얀센 알 앤드 디 아일랜드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020097000754A 2006-06-23 2007-06-22 2-(치환된-아미노)-벤조티아졸 설폰아미드 ｈｉｖ 프로테아제 저해제 Expired - Fee Related KR101419320B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06116003.2 2006-06-23
EP06116003 2006-06-23
PCT/EP2007/056235 WO2007147884A1 (en) 2006-06-23 2007-06-22 2-(substituted-amino)-benzothiazole sulfonamide hiv protease inhibitors

Publications (2)

Publication Number Publication Date
KR20090024257A KR20090024257A (ko) 2009-03-06
KR101419320B1 true KR101419320B1 (ko) 2014-07-14

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Family Applications (1)

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KR1020097000754A Expired - Fee Related KR101419320B1 (ko) 2006-06-23 2007-06-22 2-(치환된-아미노)-벤조티아졸 설폰아미드 ｈｉｖ 프로테아제 저해제

Country Status (30)

Country Link
US (1) US8202887B2 (enExample)
EP (1) EP2035432B1 (enExample)
JP (1) JP5232776B2 (enExample)
KR (1) KR101419320B1 (enExample)
CN (1) CN101479275B (enExample)
AP (1) AP2069A (enExample)
AR (1) AR061619A1 (enExample)
AT (1) ATE544769T1 (enExample)
AU (1) AU2007262943B2 (enExample)
BR (1) BRPI0713487B1 (enExample)
CA (1) CA2653233C (enExample)
CL (1) CL2007001826A1 (enExample)
CY (1) CY1112971T1 (enExample)
DK (1) DK2035432T3 (enExample)
EA (1) EA016387B1 (enExample)
ES (1) ES2381129T3 (enExample)
IL (1) IL195381A (enExample)
JO (1) JO2841B1 (enExample)
MX (1) MX2009000160A (enExample)
MY (1) MY146805A (enExample)
NZ (1) NZ573286A (enExample)
PE (1) PE20080342A1 (enExample)
PL (1) PL2035432T3 (enExample)
PT (1) PT2035432E (enExample)
SI (1) SI2035432T1 (enExample)
TW (1) TWI415851B (enExample)
UA (1) UA96445C2 (enExample)
UY (1) UY30416A1 (enExample)
WO (1) WO2007147884A1 (enExample)
ZA (1) ZA200810350B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3090B1 (ar) 2009-12-11 2017-03-15 Janssen Sciences Ireland Uc 5- امينو-4- هيدروكسي-بنتويل اميدات
MA34397B1 (fr) 2010-07-02 2013-07-03 Gilead Sciences Inc Dérivés d'acide napht-2-ylacétique dans le traitement du sida
WO2012003498A1 (en) 2010-07-02 2012-01-05 Gilead Sciences, Inc. 2 -quinolinyl- acetic acid derivatives as hiv antiviral compounds
US9024038B2 (en) 2010-12-27 2015-05-05 Purdue Research Foundation Compunds and methods for treating HIV
WO2012145728A1 (en) * 2011-04-21 2012-10-26 Gilead Sciences, Inc. Benzothiazole compounds and their pharmaceutical use
WO2013103724A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids
WO2013103738A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. Napthalene acetic acid derivatives against hiv infection
EP3070081B1 (en) 2012-04-20 2018-02-28 Gilead Sciences, Inc. Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
US12083099B2 (en) 2020-10-28 2024-09-10 Accencio LLC Methods of treating symptoms of coronavirus infection with viral protease inhibitors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040116485A1 (en) 2001-02-14 2004-06-17 Surleraux Dominique Louis Nestor Ghislain Broad spectrum 2-(substituted-amino)-benzothiazole sulfonamide hiv protease inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI286476B (en) * 2001-12-12 2007-09-11 Tibotec Pharm Ltd Combination of cytochrome P450 dependent protease inhibitors
BR0305717A (pt) * 2002-08-02 2004-09-28 Tibotec Pharm Ltd Inibidores da protease do hiv 2-amino-benzotiazol sulfonamida de amplo espectro
EP1670448B1 (en) * 2003-09-30 2007-11-21 Tibotec Pharmaceuticals Ltd. Hcv inhibiting sulfonamides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040116485A1 (en) 2001-02-14 2004-06-17 Surleraux Dominique Louis Nestor Ghislain Broad spectrum 2-(substituted-amino)-benzothiazole sulfonamide hiv protease inhibitors

Also Published As

Publication number Publication date
CL2007001826A1 (es) 2008-01-18
ZA200810350B (en) 2010-05-26
JO2841B1 (en) 2014-09-15
EA016387B1 (ru) 2012-04-30
SI2035432T1 (sl) 2012-06-29
EP2035432B1 (en) 2012-02-08
PT2035432E (pt) 2012-04-24
US8202887B2 (en) 2012-06-19
UA96445C2 (ru) 2011-11-10
PE20080342A1 (es) 2008-04-25
CA2653233C (en) 2015-09-29
NZ573286A (en) 2011-09-30
HK1125633A1 (en) 2009-08-14
US20090209583A1 (en) 2009-08-20
EP2035432A1 (en) 2009-03-18
IL195381A (en) 2013-01-31
UY30416A1 (es) 2008-01-31
JP5232776B2 (ja) 2013-07-10
TW200817416A (en) 2008-04-16
PL2035432T3 (pl) 2012-07-31
JP2009541272A (ja) 2009-11-26
IL195381A0 (en) 2009-08-03
AP2008004679A0 (en) 2008-12-31
BRPI0713487B1 (pt) 2022-07-26
EA200970052A1 (ru) 2009-04-28
BRPI0713487A2 (enExample) 2012-11-13
AU2007262943A1 (en) 2007-12-27
MX2009000160A (es) 2009-01-23
KR20090024257A (ko) 2009-03-06
MY146805A (en) 2012-09-28
CY1112971T1 (el) 2016-04-13
AR061619A1 (es) 2008-09-10
DK2035432T3 (da) 2012-05-14
ES2381129T3 (es) 2012-05-23
BRPI0713487A8 (pt) 2018-01-02
ATE544769T1 (de) 2012-02-15
AP2069A (en) 2009-12-08
AU2007262943B2 (en) 2012-04-12
TWI415851B (zh) 2013-11-21
WO2007147884A1 (en) 2007-12-27
CA2653233A1 (en) 2007-12-27
CN101479275B (zh) 2012-03-07
CN101479275A (zh) 2009-07-08

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