KR101358549B1 - 조절 가능한 체적 수용을 위한 박막 프로세싱 장치 - Google Patents

조절 가능한 체적 수용을 위한 박막 프로세싱 장치 Download PDF

Info

Publication number
KR101358549B1
KR101358549B1 KR1020127012234A KR20127012234A KR101358549B1 KR 101358549 B1 KR101358549 B1 KR 101358549B1 KR 1020127012234 A KR1020127012234 A KR 1020127012234A KR 20127012234 A KR20127012234 A KR 20127012234A KR 101358549 B1 KR101358549 B1 KR 101358549B1
Authority
KR
South Korea
Prior art keywords
slide
liquid
sample
cover
platen assembly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020127012234A
Other languages
English (en)
Korean (ko)
Other versions
KR20120107074A (ko
Inventor
브라이언 하워드 크램
케빈 데이비드 마샬
크리스틴 체
티모시 제임스 켈러
오스틴 미첼 애쉬비
Original Assignee
벤타나 메디컬 시스템즈, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 벤타나 메디컬 시스템즈, 인코포레이티드 filed Critical 벤타나 메디컬 시스템즈, 인코포레이티드
Publication of KR20120107074A publication Critical patent/KR20120107074A/ko
Application granted granted Critical
Publication of KR101358549B1 publication Critical patent/KR101358549B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
KR1020127012234A 2009-11-13 2010-11-15 조절 가능한 체적 수용을 위한 박막 프로세싱 장치 Expired - Fee Related KR101358549B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26126709P 2009-11-13 2009-11-13
US61/261,267 2009-11-13
PCT/US2010/056752 WO2011060387A1 (en) 2009-11-13 2010-11-15 Thin film processing apparatuses for adjustable volume accommodation

Publications (2)

Publication Number Publication Date
KR20120107074A KR20120107074A (ko) 2012-09-28
KR101358549B1 true KR101358549B1 (ko) 2014-02-05

Family

ID=43992102

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127012234A Expired - Fee Related KR101358549B1 (ko) 2009-11-13 2010-11-15 조절 가능한 체적 수용을 위한 박막 프로세싱 장치

Country Status (11)

Country Link
US (2) US8911815B2 (https=)
EP (1) EP2499500B1 (https=)
JP (2) JP5611363B2 (https=)
KR (1) KR101358549B1 (https=)
CN (1) CN102687023B (https=)
AU (1) AU2010320039B2 (https=)
BR (1) BR112012011181A2 (https=)
CA (1) CA2778837C (https=)
IL (1) IL219086A (https=)
IN (1) IN2012DN03245A (https=)
WO (1) WO2011060387A1 (https=)

Families Citing this family (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
DE102009032703A1 (de) * 2009-07-09 2011-01-13 Mtu Aero Engines Gmbh Vorrichtung und Verfahren zum Anordnen eines Bauteils an einem Bauteilträger
US9075225B2 (en) 2009-10-28 2015-07-07 Alentic Microscience Inc. Microscopy imaging
US20140152801A1 (en) 2009-10-28 2014-06-05 Alentic Microscience Inc. Detecting and Using Light Representative of a Sample
US9041790B2 (en) 2009-10-28 2015-05-26 Alentic Microscience Inc. Microscopy imaging
US10746752B2 (en) 2009-11-13 2020-08-18 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
WO2014102160A1 (en) * 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Automated specimen processing systems and methods of using the same
US9498791B2 (en) 2009-11-13 2016-11-22 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
JP5611363B2 (ja) 2009-11-13 2014-10-22 ベンタナ メディカル システムズ， インコーポレイテッド 調整可能な体積を収容する薄膜処理装置
US10509216B2 (en) 2012-12-26 2019-12-17 Ventana Medical Systems, Inc. Specimen processing systems and methods for aligning slides
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
WO2012048154A1 (en) 2010-10-06 2012-04-12 Biocare Medical, Llc Methods and systems for efficient processing of biological samples
JP5801410B2 (ja) * 2010-11-10 2015-10-28 コンスティテューション・メディカル・インコーポレイテッドＣｏｎｓｔｉｔｕｔｉｏｎ Ｍｅｄｉｃａｌ， Ｉｎｃ． 検査用に生物試料を準備するための自動化されたシステムおよび方法
US9945763B1 (en) 2011-02-18 2018-04-17 Biocare Medical, Llc Methods and systems for immunohistochemistry heat retrieval of biological samples
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
US8932543B2 (en) * 2011-09-21 2015-01-13 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
WO2013071358A2 (en) * 2011-11-16 2013-05-23 Leica Biosystems Melbourne Pty Ltd Biological sample treatment apparatus
IN2014CN04294A (https=) * 2011-11-16 2015-09-04 Leica Biosystems Melbourne Pty
WO2013152330A1 (en) * 2012-04-06 2013-10-10 Ventana Medical Systems, Inc. Method and device for the homogeneous distribution of suspended cell components
ITRM20120436A1 (it) * 2012-09-13 2014-03-14 System Optimal Solution S R L Elemento per la realizzazione di repliche di indagini superficiali di materiali e metodo atto a realizzare tali indagini
JP6253657B2 (ja) 2012-10-08 2017-12-27 ヴェンタナ メディカル システムズ， インク． 有色素サンプルを明確化するための方法、キット、及びシステム
EP4592400A3 (en) 2012-10-17 2025-10-29 10x Genomics Sweden AB Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
US9989448B2 (en) 2012-12-26 2018-06-05 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
CA2893501A1 (en) * 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Specimen processing systems and methods for aligning slides
US11274998B2 (en) 2012-12-26 2022-03-15 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
BR112015015413A2 (pt) * 2012-12-26 2017-07-11 Ventana Med Syst Inc aparelho de aquecimento de lâmina, método para aquecer um espécime biológico conduzido em uma lâmina e sistema para aquecer uma lâmina portadora de espécime
JP5981664B2 (ja) * 2012-12-26 2016-08-31 ベンタナ メディカル システムズ， インコーポレイテッド 対向部および対向部を有する自動検体処理システム
JP6117936B2 (ja) * 2012-12-26 2017-04-19 ベンタナ メディカル システムズ， インコーポレイテッド 標本処理システムおよび蒸発を抑える方法
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
USD728120S1 (en) 2013-03-15 2015-04-28 Ventana Medical Systems, Inc. Arcuate member for moving liquids along a microscope slide
ES2939124T3 (es) 2013-04-05 2023-04-19 Roche Diagnostics Hematology Inc Sistemas y procedimientos automatizados para preparar muestras biológicas para su examen
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
CA2916662C (en) 2013-06-25 2022-03-08 Prognosys Biosciences, Inc. Methods and systems for determining spatial patterns of biological targets in a sample
WO2014205576A1 (en) * 2013-06-26 2014-12-31 Alentic Microscience Inc. Sample processing improvements for microscopy
CN111089980B (zh) * 2013-12-13 2023-08-15 文塔纳医疗系统公司 生物样本的自动化组织学处理及相关的技术
JP6302066B2 (ja) 2013-12-13 2018-03-28 ベンタナ メディカル システムズ， インコーポレイテッド 顕微鏡スライドを熱処理する自動化された処理システムおよび方法
CN105980828B (zh) 2013-12-13 2021-12-17 文塔纳医疗系统公司 用于生物标本组织处理的染色试剂和其它液体及关联技术
AU2015239720B2 (en) 2014-03-31 2019-07-11 Ventana Medical Systems, Inc. Automated specimen processing systems and multistep processing of microscope slides
WO2015197742A1 (en) * 2014-06-27 2015-12-30 Ventana Medical Systems, Inc. Automated specimen processing systems and methods of detecting specimen-bearing microscope slides
CN104280280B (zh) * 2014-10-13 2016-12-07 赵烨梁 一种微漏进样法制备单分子样品的装置
JP2017532971A (ja) 2014-10-29 2017-11-09 コーニング インコーポレイテッド 細胞培養集合体を生成するためのマイクロウェル設計および製造
EP3212759A1 (en) 2014-10-29 2017-09-06 Corning Incorporated Cell culture insert
US10209166B2 (en) 2014-11-18 2019-02-19 Alfonso Heras System and method for processing biological specimens
CA2970258C (en) 2015-02-27 2022-06-21 Ventana Medical Systems, Inc. Assay reaction controller magazine
EP3901282B1 (en) 2015-04-10 2023-06-28 Spatial Transcriptomics AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
WO2016190111A1 (ja) * 2015-05-26 2016-12-01 オリンパス株式会社 検体染色装置および検体染色方法
AU2016286294B2 (en) * 2015-07-02 2019-09-19 Ventana Medical Systems, Inc. Opposables incorporating fluid control elements and automated specimen processing systems
CN105092865B (zh) * 2015-07-23 2017-07-18 爱威科技股份有限公司 试纸条淋样槽、淋样系统、干化分析仪及其淋样与清洗方法
CN113376364B (zh) 2015-08-10 2025-02-25 上海宜晟生物科技有限公司 步骤简化、小样品、快速、易使用的生物/化学分析装置和方法
MX392709B (es) 2015-09-14 2025-03-24 Essenlix Corp Dispositivo y sistema para recolectar y analizar condensado de vapor, particularmente condensado de exhalación de la respiración y un método para usarlo.
WO2017048871A1 (en) 2015-09-14 2017-03-23 Essenlix Corp. Device and system for analyzing a sample, particularly blood, as well as methods of using the same
ITUB20155913A1 (it) * 2015-11-26 2017-05-26 Delcon S R L Apparecchiatura e metodo per la colorazione di vetrini
EP3397940B1 (en) 2015-12-28 2022-12-21 Ventana Medical Systems, Inc. Opposables incorporating onboard reagents and automated specimen processing systems
EP3449234B1 (en) 2016-04-27 2020-09-02 Ventana Medical Systems, Inc. System and method for real-time volume control on microscope slides
CN110312473B (zh) 2016-12-21 2023-04-07 艾森利克斯公司 用于认证样本的装置和方法及其使用
DE102016225885B4 (de) * 2016-12-21 2023-12-21 Prime23 GmbH Vorrichtung und Verfahren zum Benetzen von biologischem Material
JP7003158B2 (ja) 2017-02-07 2022-01-20 エッセンリックス コーポレーション 圧縮開放流アッセイおよび使用
CN118347819A (zh) * 2017-02-08 2024-07-16 爱威科技股份有限公司 一种样本染色装置
US10823645B2 (en) 2017-02-08 2020-11-03 Essenlix Corporation Sample collection and handling for delayed analysis
CA3052986A1 (en) * 2017-02-08 2018-08-16 Essenlix Corporation Molecular manipulation and assay with controlled temperature
CN120685901A (zh) 2017-02-08 2025-09-23 上海宜晟生物科技有限公司 数字测定
CA3052809A1 (en) 2017-02-08 2018-08-23 Essenlix Corporation Qmax assays and applications
WO2018148469A1 (en) 2017-02-08 2018-08-16 Essenlix Corp. Bio/chemical material extraction and assay
CA3053132A1 (en) 2017-02-09 2018-08-16 Essenlix Corp. Assay with amplification
US11604148B2 (en) 2017-02-09 2023-03-14 Essenlix Corporation Colorimetric assays
WO2018148607A1 (en) 2017-02-09 2018-08-16 Essenlix Corporation Assay using different spacing heights
US12350680B2 (en) 2017-02-15 2025-07-08 Essenlix Corporation Assay with rapid temperature change
US12017218B2 (en) * 2017-02-15 2024-06-25 International Business Machines Corporation Hybrid microfluidics devices
US11523752B2 (en) 2017-02-16 2022-12-13 Essenlix Corporation Assay for vapor condensates
CN110462370A (zh) * 2017-03-31 2019-11-15 X-Zell公司 自动载玻片染色和冷却系统
CN121103450A (zh) 2017-05-23 2025-12-12 上海宜晟生物科技有限公司 用于测定的样品温度的快速变化
EP3631410B1 (en) * 2017-05-26 2024-08-28 Ventana Medical Systems, Inc. Non-contact, on-slide fluid mixing
BR112019026335A2 (pt) 2017-06-12 2020-07-21 Essenlix Corporation ensaio homogêneo
JP7245222B2 (ja) 2017-07-14 2023-03-23 コーニング インコーポレイテッド 手動又は自動で培地を交換するための３ｄ細胞培養容器
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
US11243201B2 (en) 2017-08-01 2022-02-08 Essenlix Corporation Sample collection, holding and assaying
WO2019028133A1 (en) 2017-08-01 2019-02-07 Essenlix Corporation DEVICES AND METHODS FOR EXAMINING THE EFFECTS OF MEDICINE ON MICROORGANISMS
CN111094966B (zh) * 2017-09-21 2023-07-11 浜松光子学株式会社 试样支撑体
WO2019075244A1 (en) 2017-10-11 2019-04-18 Essenlix Corporation CONTAINING A LIQUID SAMPLE
US11393561B2 (en) 2017-10-13 2022-07-19 Essenlix Corporation Devices and methods for authenticating a medical test and use of the same
US11221280B2 (en) * 2017-10-25 2022-01-11 Hitachi High-Tech Corporation Method of preparing biological tissue sample and method of observing biological tissue section sample
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
WO2019118652A1 (en) 2017-12-12 2019-06-20 Essenlix Corporation Sample manipulation and assay with rapid temperature change
US11510608B2 (en) 2017-12-14 2022-11-29 Essenlix Corporation Devices, systems, and methods for monitoring hair
AU2018391801B2 (en) 2017-12-24 2022-12-22 Ventana Medical Systems, Inc. Phenol-free acid-fast staining composition and use thereof
EP3729047A2 (en) 2017-12-24 2020-10-28 Ventana Medical Systems, Inc. Eosin staining techniques
WO2019140334A1 (en) 2018-01-11 2019-07-18 Essenlix Corporation Homogeneous assay (ii)
JP2021510894A (ja) 2018-01-11 2021-04-30 ベンタナ メディカル システムズ， インコーポレイテッド 曇り止めバーコード・リーダ
WO2020013845A1 (en) * 2018-07-13 2020-01-16 Corning Incorporated Cell culture vessels with stabilizer devices
CN111065725B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 包括具有互联的壁的微板的流体装置
JP7171695B2 (ja) 2018-07-13 2022-11-15 コーニング インコーポレイテッド 液体培地送達面を含む側壁を有するマイクロキャビティ皿
EP3824266B1 (en) 2018-07-16 2022-11-23 Ventana Medical Systems, Inc. Automated slide staining system and method for processing a specimen
EP3824265B1 (en) 2018-07-16 2024-02-14 Ventana Medical Systems, Inc. Automated staining system
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
US12529094B2 (en) 2018-12-10 2026-01-20 10X Genomics, Inc. Imaging system hardware
WO2020123316A2 (en) 2018-12-10 2020-06-18 10X Genomics, Inc. Methods for determining a location of a biological analyte in a biological sample
KR102833793B1 (ko) * 2018-12-20 2025-07-16 라이카 바이오시스템즈 멜버른 피티와이 엘티디 슬라이드 출력 모듈
MX392907B (es) * 2019-02-21 2025-03-20 Jesùs Raùl Beltran Ramìrez Aparato para el procesamiento inmunohistoquímico de múltiples muestras histológicas
US11712177B2 (en) 2019-08-12 2023-08-01 Essenlix Corporation Assay with textured surface
US20240077712A1 (en) * 2019-10-16 2024-03-07 Hitachi High-Tech Corporation Microscope Slide and Method for Selecting the Same
US12157124B2 (en) 2019-11-06 2024-12-03 10X Genomics, Inc. Imaging system hardware
US11768175B1 (en) 2020-03-04 2023-09-26 10X Genomics, Inc. Electrophoretic methods for spatial analysis
US11846643B2 (en) * 2020-03-27 2023-12-19 Alpha Technologies Services Llc Test sample handling system with rotary carousel
DE102020204670A1 (de) * 2020-04-14 2021-10-14 Prime23 GmbH Vorrichtung und Verfahren zum Benetzen von biologischen Material mit wenigstens einer Flüssigkeit sowie eine Halteeinrichtung
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
EP4421186B1 (en) 2020-06-08 2025-08-13 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
WO2021252747A1 (en) * 2020-06-10 2021-12-16 1Ox Genomics, Inc. Fluid delivery methods
WO2022061150A2 (en) 2020-09-18 2022-03-24 10X Geonomics, Inc. Sample handling apparatus and image registration methods
EP4729631A2 (en) 2020-12-21 2026-04-22 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
WO2022249191A1 (en) * 2021-05-27 2022-12-01 Scopio Labs Ltd. Systems and methods for coverslipping
WO2022256503A1 (en) 2021-06-03 2022-12-08 10X Genomics, Inc. Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
WO2023091750A1 (en) * 2021-11-19 2023-05-25 Cornell University Surface-patterned, omniphobic tiles (spots), fabrication, loading, and use thereof
WO2023102118A2 (en) 2021-12-01 2023-06-08 10X Genomics, Inc. Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis
WO2023122033A1 (en) 2021-12-20 2023-06-29 10X Genomics, Inc. Self-test for pathology/histology slide imaging device
WO2024107736A2 (en) * 2022-11-15 2024-05-23 Waters Technologies Corporation Pressed and mixed thin film enzymatic reactor and methods of making the same
WO2024237277A1 (ja) * 2023-05-18 2024-11-21 株式会社Ｓｃｒｅｅｎホールディングス 標本封入方法および標本封入装置
WO2025024557A1 (en) * 2023-07-25 2025-01-30 Ruby Robotics Inc Staining methods for automated systems

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030203493A1 (en) 2002-04-26 2003-10-30 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms
US20050153453A1 (en) 1990-03-02 2005-07-14 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US20050186114A1 (en) 2002-04-15 2005-08-25 Kurt Reinhardt Automated high volume slide processing system

Family Cites Families (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3551023A (en) 1969-01-17 1970-12-29 Ibm Pathology specimen processing method and article
US3556633A (en) 1969-01-17 1971-01-19 Winifred Liu Mutschmann Specimen carrying slide with runoff trough
US3672745A (en) 1970-06-29 1972-06-27 Propper Mfg Co Inc Bevelled edge microscope slide
GB1457137A (en) 1973-08-16 1976-12-01 Wyeth John & Brother Ltd Apparatus for handling coverslips
FR2263502B1 (https=) * 1974-03-06 1976-12-10 Ass Ctre Transfusion San
US3961346A (en) 1975-01-30 1976-06-01 Miles Laboratories, Inc. Liquid inspection slide
US4023949A (en) 1975-08-04 1977-05-17 Schlom Leslie A Evaporative refrigeration system
SE403940B (sv) 1976-02-26 1978-09-11 Cytologiska Centrallab Sett och anordning for maskinell applicering av teckplattor pa med preparat for mikroskopisk undersokning forsedda objektglas
US4146414A (en) 1977-05-09 1979-03-27 Cytologiska Centrallaboratoriet Ab Method for applying cover-slips to slides carrying specimens for microscopic examination
US4203797A (en) 1977-05-09 1980-05-20 Cytologiska Centrallaboratoriet Ab Method of and apparatus for applying cover-slips to slides carrying specimens for microscopic examination
US4418527A (en) 1980-04-21 1983-12-06 Schlom Leslie A Precooler for gas turbines
US4359013A (en) 1980-09-08 1982-11-16 Prevo Donald L Device for spreading monolayered films
US4392450A (en) 1981-02-12 1983-07-12 Prevo Donald L Device for spreading monolayered films
US4336765A (en) 1981-06-12 1982-06-29 Coughlin Vincent D Vacuum work piece holder
JPS5840519A (ja) * 1981-09-03 1983-03-09 Meisei Electric Co Ltd 顕微鏡用標本の封入方法
JPS58140457U (ja) * 1982-03-18 1983-09-21 明星電気株式会社 顕微鏡標本作成装置の試料固定機構
US4428793A (en) 1981-08-25 1984-01-31 Meisei Electric Co., Ltd. Preparation method for a microscopic specimen and a device therefor
US4597982A (en) 1982-03-18 1986-07-01 Delameter William D Method for processing flexible sheets
US4731335A (en) 1985-09-13 1988-03-15 Fisher Scientific Company Method for treating thin samples on a surface employing capillary flow
US5023187A (en) 1985-09-13 1991-06-11 Fisher Scientific Company Method and device for accelerated treatment of thin sample on surface
US4790640A (en) 1985-10-11 1988-12-13 Nason Frederic L Laboratory slide
US5002736A (en) 1987-03-31 1991-03-26 Fisher Scientific Co. Microscope slide and slide assembly
US4849340A (en) 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
GB8722902D0 (en) 1987-09-30 1987-11-04 Shandon Southern Prod Tissue &c processing
US5503803A (en) 1988-03-28 1996-04-02 Conception Technologies, Inc. Miniaturized biological assembly
US4911782A (en) 1988-03-28 1990-03-27 Cyto-Fluidics, Inc. Method for forming a miniaturized biological assembly
US5188963A (en) 1989-11-17 1993-02-23 Gene Tec Corporation Device for processing biological specimens for analysis of nucleic acids
US5281516A (en) 1988-08-02 1994-01-25 Gene Tec Corporation Temperature control apparatus and method
US5346672A (en) 1989-11-17 1994-09-13 Gene Tec Corporation Devices for containing biological specimens for thermal processing
ES2104699T3 (es) 1990-03-30 1997-10-16 Neuromedical Systems Inc Metodo y sistema automatizados de clasificar una muestra citologica.
US5075079A (en) 1990-05-21 1991-12-24 Technicon Instruments Corporation Slide analysis system
US5273905A (en) 1991-02-22 1993-12-28 Amoco Corporation Processing of slide mounted material
US5189751A (en) 1991-03-21 1993-03-02 Gemtech, Inc. Vibrating toothbrush using a magnetic driver
JP3320444B2 (ja) 1992-04-06 2002-09-03 株式会社千代田製作所 染色装置用ノズル洗浄装置
US5256241A (en) 1992-08-28 1993-10-26 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method for controlling protein crystallization
NO179729C (no) 1992-12-11 1996-12-04 Oeystein H Ljungmann Apparat for automatisk påklebing av dekkglass på objektglass
US5364790A (en) 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
JP3292765B2 (ja) 1993-07-30 2002-06-17 株式会社千代田製作所 顕微鏡標本の染色方法とその装置
AUPM352194A0 (en) 1994-01-25 1994-02-17 Australian Biomedical Corporation Limited Instrument for automatically applying coverslips and method
AUPN038995A0 (en) 1995-01-05 1995-01-27 Australian Biomedical Corporation Limited Method and apparatus for human or animal cell sample treatment
GB9506312D0 (en) 1995-03-28 1995-05-17 Medical Res Council Improvements in or relating to sample processing
AUPN357495A0 (en) 1995-06-15 1995-07-06 Australian Biomedical Corporation Limited Coverslip pick-up and laydown apparatus
JPH0943118A (ja) * 1995-07-31 1997-02-14 Aloka Co Ltd 生物組織の処理装置
GB9518129D0 (en) 1995-09-06 1995-11-08 Zynocyte Ltd Stain and capillary slide
US5650332A (en) 1995-11-14 1997-07-22 Coulter International Corp. Method for the preparation of microscope slides
JP3947226B2 (ja) * 1996-01-16 2007-07-18 デュレル・コーポレーション ロールコーティングされたｅｌパネル
AUPN762196A0 (en) 1996-01-17 1996-02-08 Australian Biomedical Corporation Limited Specimen preparation apparatus
AUPN923596A0 (en) * 1996-04-12 1996-05-09 Australian Biomedical Corporation Limited Method and apparatus for treatment of human or animal cell samples
US6544395B1 (en) 1996-05-06 2003-04-08 Helena Laboratories Corporation System for the application of samples on a substrate
JP3419430B2 (ja) 1996-08-21 2003-06-23 日本電子株式会社 生化学自動分析装置における試薬注入攪拌装置
JP3753526B2 (ja) 1996-12-18 2006-03-08 サクラ精機株式会社 顕微鏡標本のカバーガラス貼着方法と装置
US6703247B1 (en) 1996-12-23 2004-03-09 American Registry Of Pathology Apparatus and methods for efficient processing of biological samples on slides
AUPO439496A0 (en) * 1996-12-24 1997-01-23 Australian Biomedical Corporation Pty. Ltd. Smearer mechanism
JPH10197424A (ja) * 1997-01-14 1998-07-31 Chiyoda Manufacturing Co Ltd 顕微鏡標本のカバーガラス取付け方法及び装置
US6489171B1 (en) 1997-04-18 2002-12-03 Cell Marque Corporation Chemical dispensing system and method
US6567214B2 (en) 1997-09-04 2003-05-20 Andrew E. Lorincz Microscope slide having culture media and method for use
US5812312A (en) 1997-09-04 1998-09-22 Lorincz; Andrew Endre Microscope slide
US6239906B1 (en) 1997-09-04 2001-05-29 Andrew E. Lorincz Flexible microscope slide
US6486947B2 (en) 1998-07-22 2002-11-26 Ljl Biosystems, Inc. Devices and methods for sample analysis
WO1999034190A1 (en) 1997-12-23 1999-07-08 Dako A/S Cartridge device for processing a sample mounted on a surface of a support member
US6083759A (en) 1997-12-30 2000-07-04 University Of Hawaii Blood smearing cassette
US6037168A (en) 1997-12-31 2000-03-14 Cytonix Corporation Microbiological assembly comprising resealable closure means
JPH11202215A (ja) * 1998-01-09 1999-07-30 Chiyoda Mfg Co Ltd 顕微鏡標本のカバーガラス貼着方法と装置
US6589650B1 (en) 2000-08-07 2003-07-08 3M Innovative Properties Company Microscope cover slip materials
US20030211630A1 (en) 1998-02-27 2003-11-13 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
JP3847559B2 (ja) * 1998-02-27 2006-11-22 ベンタナ・メデイカル・システムズ・インコーポレーテツド 独立スライド加熱器を有する自動化分子病理学装置
CA2325583A1 (en) 1998-03-24 1999-09-30 Jianghong Shui Automated staining apparatus
US6180314B1 (en) 1998-05-27 2001-01-30 Becton, Dickinson And Company Method for preparing thin liquid samples for microscopic analysis
US6358475B1 (en) 1998-05-27 2002-03-19 Becton, Dickinson And Company Device for preparing thin liquid for microscopic analysis
NO986025D0 (no) * 1998-12-21 1998-12-21 Torstein Ljungmann Maskin for automatisk pÕklebing av dekkglass pÕ objektglass
US6544798B1 (en) 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6568447B1 (en) 1999-05-11 2003-05-27 Kabushiki Kaisha Tiyoda Seisakusho Cover glass adhering device
US6474386B2 (en) 1999-08-25 2002-11-05 Kabushiki Kaisha Tiyoda Seisakusho Cover glass adhering device
US6403931B1 (en) 1999-10-07 2002-06-11 Ventana Medical Systems, Inc. Slide heater calibrator and temperature converter apparatus and method
US6690470B1 (en) 1999-11-04 2004-02-10 Arcturus Engineering, Inc. Automated laser capture microdissection
USD445909S1 (en) 1999-11-11 2001-07-31 Hemocue Ab Cuvette
NO310385B1 (no) 1999-11-17 2001-06-25 Torstein Ljungmann Anordning for automatisk påklebing av dekkglass på objektglass
EP1257349B1 (en) 2000-02-23 2008-08-13 Schlom, Leslie A heat exchanger for cooling and for a pre-cooler for turbine intake air conditioning
USD464141S1 (en) 2000-10-17 2002-10-08 Acon Laboratories, Inc. Test device platform
US6717657B2 (en) 2001-01-02 2004-04-06 Becton, Dickinson And Company Apparatus for measuring the volume of individual red blood cells
US6544793B2 (en) 2001-04-27 2003-04-08 Becton, Dickinson And Company Method for calibrating a sample analyzer
US6485918B1 (en) 2001-07-02 2002-11-26 Packard Bioscience Corporation Method and apparatus for incubation of a liquid reagent and target spots on a microarray substrate
DE10144048B4 (de) 2001-09-07 2012-09-20 Leica Mikrosysteme Gmbh Vorrichtung und Verfahren zum Handhaben von Deckgläsern für Objektträger
US7425306B1 (en) 2001-09-11 2008-09-16 Ventana Medical Systems, Inc. Slide heater
US20030087292A1 (en) 2001-10-04 2003-05-08 Shiping Chen Methods and systems for promoting interactions between probes and target molecules in fluid in microarrays
DK1499548T3 (da) 2002-04-26 2008-09-01 Ventana Med Syst Inc Fremgangsmåde og apparat til automatiseret pålægning af dækglas
US7919308B2 (en) 2002-06-14 2011-04-05 Agilent Technologies, Inc. Form in place gaskets for assays
AUPS309002A0 (en) * 2002-06-20 2002-07-11 Vision Biosystems Limited A covertile for a substrate
CN105258988A (zh) 2002-06-20 2016-01-20 徕卡病理系统墨尔本控股有限公司 带有排放机构的生物反应装置
US7063758B2 (en) 2002-07-29 2006-06-20 Three Bond Co., Ltd. Laminating apparatus and laminating method
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
USD495806S1 (en) 2002-08-08 2004-09-07 Exiqon A/S Slide for use in chemical or biochemical procedures
US7186383B2 (en) 2002-09-27 2007-03-06 Ast Management Inc. Miniaturized fluid delivery and analysis system
US20040082058A1 (en) 2002-10-29 2004-04-29 Arthur Schleifer Array hybridization apparatus and method for making uniform sample volumes
US7850912B2 (en) 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
WO2004083824A1 (en) 2003-03-20 2004-09-30 Dakocytomation Denmark A/S System for establishing a sample cover on a substrate
US7468160B2 (en) 2003-12-05 2008-12-23 Agilent Technologies, Inc. Devices and methods for performing array based assays
WO2005064309A1 (en) 2003-12-23 2005-07-14 Ventana Medical Systems, Inc. Method and apparatus for efficient thin film fluid
WO2006012498A1 (en) 2004-07-23 2006-02-02 Ventana Medical Systems, Inc. Method and apparatus for applying fluids to a biological sample
DE102004037848B4 (de) 2004-08-04 2007-03-29 Advalytix Ag Probenträgerwaschbehälter, Probenträgerwaschstation, System zum Waschen von Probenträgern und Verfahren zum Waschen von Probenträgern
US7481980B2 (en) 2004-09-08 2009-01-27 Intavis Bioanalytical Instruments Ag Device for staining and hybridization reactions
US7300804B2 (en) 2004-11-15 2007-11-27 Beckman Coulter, Inc. Method and apparatus for controlling the uniform smearing of a biological liquid over a substrate
US8034610B2 (en) * 2005-04-21 2011-10-11 Celerus Diagnostics, Inc. Parallel processing fluidic method and apparatus for automated rapid immunohistochemistry
JP4607703B2 (ja) * 2005-08-22 2011-01-05 東芝機械株式会社 薄切片標本作製方法
EP2013603A1 (en) 2006-04-26 2009-01-14 Quantifoil Instruments Gmbh A sample handling device for and a method of handling a sample
USD569990S1 (en) 2006-09-28 2008-05-27 Millennium Sciences Microscope slide assembly
US20110217731A1 (en) 2008-06-16 2011-09-08 Mayo Foundation For Medical Education And Research Pathology sample processing workstation
US9072576B2 (en) 2008-12-08 2015-07-07 Sunstar Inc. Linear actuator
WO2010074917A1 (en) 2008-12-24 2010-07-01 Ventana Medical Systems, Inc. Microscope-slide dryer
JP5611363B2 (ja) 2009-11-13 2014-10-22 ベンタナ メディカル システムズ， インコーポレイテッド 調整可能な体積を収容する薄膜処理装置
US9498791B2 (en) 2009-11-13 2016-11-22 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
WO2014102160A1 (en) 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Automated specimen processing systems and methods of using the same
WO2011139978A1 (en) 2010-05-04 2011-11-10 Ventana Medical Systems, Inc. Moving meniscus rinsing and mixing in cell staining
USD645971S1 (en) 2010-05-11 2011-09-27 Claros Diagnostics, Inc. Sample cassette
US20110305842A1 (en) 2010-06-11 2011-12-15 Ventana Medical Systems, Inc. Floatable opposables for applying fluids to process biological samples
EP2819775A1 (en) 2012-03-01 2015-01-07 Victorious Medical Systems ApS Method and system for distributing and agitating an amount of liquid over a microscope slide
JP5981664B2 (ja) 2012-12-26 2016-08-31 ベンタナ メディカル システムズ， インコーポレイテッド 対向部および対向部を有する自動検体処理システム
USD728120S1 (en) 2013-03-15 2015-04-28 Ventana Medical Systems, Inc. Arcuate member for moving liquids along a microscope slide

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050153453A1 (en) 1990-03-02 2005-07-14 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US20050186114A1 (en) 2002-04-15 2005-08-25 Kurt Reinhardt Automated high volume slide processing system
US20030203493A1 (en) 2002-04-26 2003-10-30 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms

Also Published As

Publication number Publication date
IL219086A0 (en) 2012-06-28
IN2012DN03245A (https=) 2015-10-23
AU2010320039B2 (en) 2013-08-15
BR112012011181A2 (pt) 2020-10-13
CA2778837C (en) 2016-01-19
HK1175845A1 (zh) 2013-07-12
US8911815B2 (en) 2014-12-16
US20150071833A1 (en) 2015-03-12
KR20120107074A (ko) 2012-09-28
CN102687023B (zh) 2016-01-06
US20130052331A1 (en) 2013-02-28
EP2499500B1 (en) 2020-12-30
JP2013511048A (ja) 2013-03-28
CA2778837A1 (en) 2011-05-19
EP2499500A1 (en) 2012-09-19
AU2010320039A1 (en) 2012-05-03
US9618430B2 (en) 2017-04-11
JP5923145B2 (ja) 2016-05-24
JP2015007646A (ja) 2015-01-15
JP5611363B2 (ja) 2014-10-22
IL219086A (en) 2017-10-31
WO2011060387A1 (en) 2011-05-19
EP2499500A4 (en) 2016-01-06
CN102687023A (zh) 2012-09-19

Similar Documents

Publication Publication Date Title
KR101358549B1 (ko) 조절 가능한 체적 수용을 위한 박막 프로세싱 장치
US9989448B2 (en) Specimen processing systems and methods for holding slides
CN104870974B (zh) 标本处理系统和用于制备试剂的方法
US12104994B2 (en) Specimen processing systems and methods for holding slides
EP2938997B1 (en) Automated specimen processing systems and methods of aligning and transporting specimen-bearing microscope slides
CN104871006B (zh) 标本处理系统和用于均匀加热载片的方法
WO2011002779A2 (en) Methods and apparatuses for applying and removing fluids for processing biological samples
US20150293341A1 (en) Specimen processing systems and methods for aligning slides
CN104902998A (zh) 标本处理系统和用于减轻蒸发的方法
HK1175845B (en) Thin film processing apparatuses for adjustable volume accommodation

Legal Events

Date Code Title Description
A201 Request for examination
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20161229

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

FPAY Annual fee payment

Payment date: 20171228

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20190128

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20190128