KR100919266B1 - 인간 파필로마 바이러스 치료법 - Google Patents
인간 파필로마 바이러스 치료법Info
- Publication number
- KR100919266B1 KR100919266B1 KR1020027017697A KR20027017697A KR100919266B1 KR 100919266 B1 KR100919266 B1 KR 100919266B1 KR 1020027017697 A KR1020027017697 A KR 1020027017697A KR 20027017697 A KR20027017697 A KR 20027017697A KR 100919266 B1 KR100919266 B1 KR 100919266B1
- Authority
- KR
- South Korea
- Prior art keywords
- hpv
- delete delete
- protein
- type
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21420200P | 2000-06-26 | 2000-06-26 | |
| US60/214,202 | 2000-06-26 | ||
| PCT/US2001/020240 WO2002000242A2 (en) | 2000-06-26 | 2001-06-26 | Human papilloma virus treatment |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020087018500A Division KR20080075560A (ko) | 2000-06-26 | 2001-06-26 | 인간 파필로마 바이러스 치료법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20030025939A KR20030025939A (ko) | 2003-03-29 |
| KR100919266B1 true KR100919266B1 (ko) | 2009-09-30 |
Family
ID=22798190
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020027017697A Expired - Fee Related KR100919266B1 (ko) | 2000-06-26 | 2001-06-26 | 인간 파필로마 바이러스 치료법 |
| KR1020087018500A Ceased KR20080075560A (ko) | 2000-06-26 | 2001-06-26 | 인간 파필로마 바이러스 치료법 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020087018500A Ceased KR20080075560A (ko) | 2000-06-26 | 2001-06-26 | 인간 파필로마 바이러스 치료법 |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US20020110566A1 (enExample) |
| EP (1) | EP1296711B1 (enExample) |
| JP (1) | JP2004512264A (enExample) |
| KR (2) | KR100919266B1 (enExample) |
| CN (1) | CN100441223C (enExample) |
| AT (1) | ATE326236T1 (enExample) |
| AU (3) | AU2001271449B2 (enExample) |
| BR (1) | BR0111956A (enExample) |
| CA (1) | CA2413543A1 (enExample) |
| CY (1) | CY1105389T1 (enExample) |
| CZ (1) | CZ20024154A3 (enExample) |
| DE (1) | DE60119734T2 (enExample) |
| DK (1) | DK1296711T3 (enExample) |
| EE (1) | EE200200709A (enExample) |
| ES (1) | ES2263637T3 (enExample) |
| HR (1) | HRP20021015A2 (enExample) |
| HU (1) | HUP0301308A3 (enExample) |
| IL (1) | IL153474A0 (enExample) |
| MX (1) | MXPA02012858A (enExample) |
| NO (1) | NO20026044L (enExample) |
| NZ (1) | NZ523408A (enExample) |
| PL (1) | PL359930A1 (enExample) |
| PT (1) | PT1296711E (enExample) |
| RU (1) | RU2282461C2 (enExample) |
| SK (1) | SK18362002A3 (enExample) |
| WO (1) | WO2002000242A2 (enExample) |
| ZA (1) | ZA200210211B (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| AU5926700A (en) | 1999-07-08 | 2001-01-30 | Stressgen Biotechnologies Corporation | Induction of a th1-like response in vitro |
| US20050226890A1 (en) * | 1999-08-12 | 2005-10-13 | Cohen David I | Tat-based vaccine compositions and methods of making and using same |
| US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
| US8128922B2 (en) | 1999-10-20 | 2012-03-06 | Johns Hopkins University | Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen |
| KR100919266B1 (ko) * | 2000-06-26 | 2009-09-30 | 엔벤타 바이오파마슈티컬스 코포레이션 | 인간 파필로마 바이러스 치료법 |
| EP1363938B1 (en) | 2000-08-03 | 2013-12-11 | Johns Hopkins University | Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen |
| US20080044435A1 (en) * | 2004-03-16 | 2008-02-21 | Cohen David I | Tat-Based Tolerogen Compositions and Methods of Making and Using Same |
| US6921534B2 (en) | 2001-02-05 | 2005-07-26 | Stressgen Biotechnologies Corporation | Hepatitis B virus treatment |
| US6649402B2 (en) * | 2001-06-22 | 2003-11-18 | Wisconsin Alumni Research Foundation | Microfabricated microbial growth assay method and apparatus |
| AU2003284239B2 (en) * | 2002-10-21 | 2008-08-21 | Eisai Inc. | Compositions and methods for treating human papillomavirus-mediated disease |
| PT1572233E (pt) * | 2002-12-20 | 2011-06-07 | Glaxosmithkline Biolog Sa | Utilização de hpv16 e hpv18 como vacina contra um ou mais de tipos de hpv oncogénicos 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 |
| EP1644048B1 (en) * | 2003-05-05 | 2015-04-29 | Johns Hopkins University | Anti-cancer dna vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein |
| CN1833030B (zh) | 2003-05-22 | 2014-07-23 | 美国弗劳恩霍夫股份有限公司 | 用于表达、传递及纯化目标多肽的重组载体分子 |
| DE10347710B4 (de) * | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| US7285386B2 (en) * | 2003-10-29 | 2007-10-23 | University Of New Mexico, And Educational Institution Of The State Of New Mexico | RhPV as a model for HPV-induced cancers |
| DE10357677A1 (de) * | 2003-12-10 | 2005-07-14 | Greiner Bio-One Gmbh | Primer und Sonden zum Nachweis genitaler HPV-Genotypen |
| US20050208482A1 (en) * | 2004-03-16 | 2005-09-22 | Cohen David I | Tat-based immunomodulatory compositions and methods for their discovery and use |
| WO2006073970A2 (en) | 2005-01-06 | 2006-07-13 | The Johns Hopkins University | Rna interference that blocks expression of pro-apoptotic proteins potentiates immunity induced by dna and transfected dendritic cell vaccines |
| US8252893B2 (en) * | 2005-01-31 | 2012-08-28 | Board Of Trustees Of The University Of Arkansas | CD8 T cell epitopes in HPV 16 E6 and E7 proteins and uses thereof |
| RU2285537C1 (ru) * | 2005-04-05 | 2006-10-20 | Автономная некоммерческая организация "Институт молекулярной диагностики (АНО "ИнМоДи") | Противоопухолевый пептидный препарат на основе фрагмента альфа-фетопротеина, его конъюгат, фармацевтическая композиция и способ лечения гормонзависимых опухолей |
| RU2283128C1 (ru) * | 2005-04-05 | 2006-09-10 | Сергей Викторович Луценко | Способ получения препарата белка из семейства стрессовых и препарат белка hsp70, полученный этим способом |
| CN101189014A (zh) * | 2005-04-27 | 2008-05-28 | 莱顿大学医学中心 | 用于治疗hpv诱导的上皮内瘤样病变的方法和手段 |
| RU2290204C1 (ru) * | 2005-07-27 | 2006-12-27 | Общество с ограниченной ответственностью "Аванген" | Рекомбинантный гибридный белок, препарат для иммунотерапии на его основе и способ иммунотерапии рецидивирующего папилломатоза гортани |
| EP1919504B1 (en) * | 2005-08-03 | 2013-10-16 | iBio, Inc. | Antibody to bacillus anthracis protective antigen |
| WO2007038083A2 (en) * | 2005-09-21 | 2007-04-05 | New York University | Heat shock proteins from mycobacterium leprae and uses thereof |
| WO2007095320A2 (en) * | 2006-02-13 | 2007-08-23 | Fraunhofer Usa, Inc. | Hpv antigens, vaccine compositions, and related methods |
| US8124103B2 (en) * | 2006-02-13 | 2012-02-28 | Fraunhofer Usa, Inc | Influenza antigens, vaccine compositions, and related methods |
| WO2008048344A2 (en) * | 2006-02-13 | 2008-04-24 | Fraunhofer Usa, Inc. | Bacillus anthracis antigens, vaccine compositions, and related methods |
| RU2316342C1 (ru) * | 2006-03-31 | 2008-02-10 | Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") | Вакцинная композиция для профилактики и лечения онкологических заболеваний, рекомбинантная плазмидная днк, обеспечивающая синтез гибридного белка, способ его получения |
| BRPI0712729A2 (pt) * | 2006-05-31 | 2013-07-02 | Nventa Biopharmaceuticals Corp | composiÇÕes hspe7 bioativas purificadas |
| US9085638B2 (en) | 2007-03-07 | 2015-07-21 | The Johns Hopkins University | DNA vaccine enhancement with MHC class II activators |
| WO2008124483A1 (en) * | 2007-04-04 | 2008-10-16 | Specigen, Inc. | Protein cage immunotherapeutics |
| CN101687024A (zh) * | 2007-04-28 | 2010-03-31 | 美国弗劳恩霍夫股份有限公司 | 锥虫抗原、疫苗组合物和相关方法 |
| US8404252B2 (en) | 2007-07-11 | 2013-03-26 | Fraunhofer Usa, Inc. | Yersinia pestis antigens, vaccine compositions, and related methods |
| CA2696764A1 (en) * | 2007-08-20 | 2009-02-26 | Fraunhofer Usa, Inc. | Prophylactic and therapeutic influenza vaccines, antigens, compositions, and methods |
| US20090117140A1 (en) * | 2007-09-26 | 2009-05-07 | Mayumi Nakagawa | Human papilloma virus dominant CD4 T cell epitopes and uses thereof |
| WO2009094006A2 (en) * | 2007-10-25 | 2009-07-30 | Wake Forest University Health Sciences | Bordetella outer-membrane protein antigens and methods of making and using the same |
| WO2009114085A2 (en) | 2008-03-03 | 2009-09-17 | The University Of Miami | Allogeneic cancer cell-based immunotherapy |
| AU2009226077B2 (en) | 2008-03-20 | 2012-04-19 | University Of Miami | Heat shock protein gp96 vaccination and methods of using same |
| WO2010037046A1 (en) | 2008-09-28 | 2010-04-01 | Fraunhofer Usa, Inc. | Humanized neuraminidase antibody and methods of use thereof |
| CA2736361C (en) * | 2008-10-31 | 2017-10-10 | Novartis Ag | Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor |
| BRPI0922301A2 (pt) * | 2008-11-28 | 2019-02-26 | Novartis Ag | combinações de inibidor de hsp90 |
| JP5692933B2 (ja) | 2009-03-23 | 2015-04-01 | ナニアールエックス セラピューティックス インコーポレイテッド | 免疫刺激HIVTat誘導体ポリペプチドによる腫瘍治療 |
| US8784819B2 (en) | 2009-09-29 | 2014-07-22 | Ibio Inc. | Influenza hemagglutinin antibodies, compositions and related methods |
| US9662510B2 (en) | 2010-07-19 | 2017-05-30 | Emblation Limited | Apparatus and method for the treatment of dermatological diseases or conditions |
| US11963716B2 (en) | 2010-07-19 | 2024-04-23 | Emblation Limited | Apparatus and method for the treatment of dermatological diseases or conditions |
| RU2438652C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинального раствора для орошения, набор и способ его получения |
| RU2438702C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинальных капсул |
| RU2438703C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинального суппозитория |
| AU2012220592A1 (en) * | 2011-02-23 | 2013-09-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Service | Combined cell based GP96-IG-SIV/HIV, recombinant GP120 protein vaccination for protection from SIV/HIV |
| US9028884B2 (en) | 2013-08-13 | 2015-05-12 | Preventamedics LLC | Medical delivery devices and methods for applying a barrier composition to a targeted skin surface |
| WO2015051245A1 (en) | 2013-10-04 | 2015-04-09 | Pin Pharma, Inc. | Immunostimulatory hiv tat derivative polypeptides for use in cancer treatment |
| GB2541749B (en) | 2015-08-31 | 2020-12-09 | Emblation Ltd | An interference suppression apparatus and method |
| US11497926B2 (en) | 2016-08-08 | 2022-11-15 | Emblation Limited | Method and apparatus for the treatment, management and/or control of pain |
| EP3600551A1 (en) | 2017-03-28 | 2020-02-05 | Emblation Limited | Stenosis treatment |
| EP3606550A2 (en) * | 2017-04-03 | 2020-02-12 | Neon Therapeutics, Inc. | Protein antigens and uses thereof |
| CN108409866A (zh) * | 2018-01-23 | 2018-08-17 | 合肥瑞城生生物科技有限公司 | 一种用于治疗和预防人乳头瘤病毒感染及相关疾病的多表位组合肽 |
| CA3108739A1 (en) | 2018-08-06 | 2020-02-13 | Nielsen Biosciences, Inc. | Treatment of warts |
| EP3909612A1 (en) * | 2020-05-12 | 2021-11-17 | Life Science Inkubator Betriebs GmbH & Co. KG | Composition of nanoparticles |
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| WO1999007860A1 (en) * | 1997-08-05 | 1999-02-18 | Stressgen Biotechnologies Corporation | Immune responses against hpv antigens elicited by compositions comprising an hpv antigen and a stress protein or an expression vector capable of expression of these proteins |
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| KR20030025939A (ko) | 인간 파필로마 바이러스 치료법 | |
| AU2001271449A1 (en) | Human papilloma virus treatment | |
| JP4198315B2 (ja) | Hpv抗原およびストレスタンパク質またはこれらのタンパク質の発現が可能な発現ベクターを含む組成物によって誘起されるhpv抗原に対する免疫応答 | |
| AU779770B2 (en) | Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins | |
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| EP1336621A2 (en) | Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins |
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