KR100827973B1 - 신규 펩티드 - Google Patents

신규 펩티드 Download PDF

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Publication number
KR100827973B1
KR100827973B1 KR1020027000758A KR20027000758A KR100827973B1 KR 100827973 B1 KR100827973 B1 KR 100827973B1 KR 1020027000758 A KR1020027000758 A KR 1020027000758A KR 20027000758 A KR20027000758 A KR 20027000758A KR 100827973 B1 KR100827973 B1 KR 100827973B1
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KR
South Korea
Prior art keywords
peptide
amino acid
based compound
ghrelin
group
Prior art date
Application number
KR1020027000758A
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English (en)
Korean (ko)
Other versions
KR20020026543A (ko
Inventor
겐지 간가와
마사야스 고지마
히로시 호소다
히사유끼 마쯔오
요시하루 미나미따께
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겐지 간가와
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Application filed by 겐지 간가와 filed Critical 겐지 간가와
Publication of KR20020026543A publication Critical patent/KR20020026543A/ko
Application granted granted Critical
Publication of KR100827973B1 publication Critical patent/KR100827973B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/463—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
KR1020027000758A 1999-07-23 2000-07-24 신규 펩티드 KR100827973B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP21000299 1999-07-23
JPJP-P-1999-00210002 1999-07-23
JPJP-P-1999-00338841 1999-11-29
JP33884199 1999-11-29
JPJP-P-2000-00126623 2000-04-26
JP2000126623 2000-04-26

Publications (2)

Publication Number Publication Date
KR20020026543A KR20020026543A (ko) 2002-04-10
KR100827973B1 true KR100827973B1 (ko) 2008-05-21

Family

ID=27329078

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027000758A KR100827973B1 (ko) 1999-07-23 2000-07-24 신규 펩티드

Country Status (16)

Country Link
US (5) US7385026B1 (es)
EP (3) EP2119785B1 (es)
JP (2) JP3471780B2 (es)
KR (1) KR100827973B1 (es)
CN (2) CN101693736B (es)
AT (2) ATE366813T1 (es)
AU (2) AU784035B2 (es)
BR (2) BR0012688A (es)
CA (2) CA2696819C (es)
CY (2) CY1107724T1 (es)
DE (2) DE60043361D1 (es)
DK (2) DK1795598T3 (es)
ES (3) ES2335235T3 (es)
IL (2) IL147652A0 (es)
PT (2) PT1197496E (es)
WO (1) WO2001007475A1 (es)

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EP1353683A4 (en) * 2000-05-30 2004-05-12 Merck & Co Inc ANALOGS BY GHRELIN
US20020187938A1 (en) * 2000-07-24 2002-12-12 Romano Deghenghi Ghrelin antagonists
IL162780A0 (en) * 2002-04-11 2005-11-20 Kenji Kangawa Method for producing modified peptide
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WO2005097830A2 (en) * 2004-04-07 2005-10-20 Aditech Pharma Ab Uses of isolated binding members capable of reducing the biological activity of secretagogue compounds
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WO2014119753A1 (ja) * 2013-01-31 2014-08-07 学校法人 東京薬科大学 マイオスタチン阻害ペプチド
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Also Published As

Publication number Publication date
CN101693736B (zh) 2020-09-11
DE60035502T2 (de) 2008-03-20
CN1362968A (zh) 2002-08-07
BR0012688A (pt) 2002-04-16
AU784035B2 (en) 2006-01-19
JP4227857B2 (ja) 2009-02-18
CA2380058C (en) 2011-08-09
DE60035502D1 (de) 2007-08-23
US20110184153A1 (en) 2011-07-28
CA2380058A1 (en) 2001-02-01
BRPI0012688B8 (pt) 2021-05-25
CA2696819C (en) 2015-07-07
EP1197496A1 (en) 2002-04-17
IL147652A0 (en) 2002-08-14
ES2288151T3 (es) 2008-01-01
US8227570B2 (en) 2012-07-24
BRPI0012688B1 (pt) 2018-06-05
AU6023100A (en) 2001-02-13
EP1197496B8 (en) 2007-10-03
CN101693736A (zh) 2010-04-14
ES2335235T3 (es) 2010-03-23
US7385026B1 (en) 2008-06-10
AU2006201580A1 (en) 2006-05-18
EP1795598B1 (en) 2009-11-18
ES2401939T3 (es) 2013-04-25
DK1197496T3 (da) 2007-10-22
EP2119785B1 (en) 2013-03-13
EP1197496B1 (en) 2007-07-11
PT1197496E (pt) 2007-08-29
US9938332B2 (en) 2018-04-10
CY1109714T1 (el) 2014-08-13
US20100240866A1 (en) 2010-09-23
ATE449174T1 (de) 2009-12-15
JP2004000251A (ja) 2004-01-08
US20130172251A1 (en) 2013-07-04
PT1795598E (pt) 2010-01-05
JP3471780B2 (ja) 2003-12-02
EP1795598A1 (en) 2007-06-13
ATE366813T1 (de) 2007-08-15
US8524871B2 (en) 2013-09-03
KR20020026543A (ko) 2002-04-10
US9573986B2 (en) 2017-02-21
CN100506844C (zh) 2009-07-01
DK1795598T3 (da) 2010-02-01
DE60043361D1 (de) 2009-12-31
AU2006201580B2 (en) 2009-01-08
EP2119785A1 (en) 2009-11-18
EP1197496A4 (en) 2002-11-20
IL147652A (en) 2010-04-29
CA2696819A1 (en) 2001-02-01
CY1107724T1 (el) 2013-04-18
US20090170763A1 (en) 2009-07-02
WO2001007475A1 (fr) 2001-02-01

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