KR100732692B1 - 프로게스테론 수용체 조절인자인 시클로티오카르바메이트유도체 - Google Patents

프로게스테론 수용체 조절인자인 시클로티오카르바메이트유도체 Download PDF

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Publication number
KR100732692B1
KR100732692B1 KR1020017014085A KR20017014085A KR100732692B1 KR 100732692 B1 KR100732692 B1 KR 100732692B1 KR 1020017014085 A KR1020017014085 A KR 1020017014085A KR 20017014085 A KR20017014085 A KR 20017014085A KR 100732692 B1 KR100732692 B1 KR 100732692B1
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KR
South Korea
Prior art keywords
substituted
alkyl
dihydro
aryl
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020017014085A
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English (en)
Korean (ko)
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KR20020000170A (ko
Inventor
장푸웬
펜섬앤드류
테리펜코유진에이.
지린
존즈토드케이.
테글리크리스토퍼엠.
콜린스마크에이.
로벨제이이.
에드워즈제임즈피.
Original Assignee
와이어쓰
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/552,354 external-priority patent/US6436929B1/en
Application filed by 와이어쓰 filed Critical 와이어쓰
Publication of KR20020000170A publication Critical patent/KR20020000170A/ko
Application granted granted Critical
Publication of KR100732692B1 publication Critical patent/KR100732692B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Detergent Compositions (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020017014085A 1999-05-04 2000-05-01 프로게스테론 수용체 조절인자인 시클로티오카르바메이트유도체 Expired - Fee Related KR100732692B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18301399P 1999-05-04 1999-05-04
US60/183,013 1999-05-04
US09/552,354 2000-04-19
US09/552,354 US6436929B1 (en) 1999-05-04 2000-04-19 Cyclothiocarbamate derivatives as progesterone receptor modulators

Publications (2)

Publication Number Publication Date
KR20020000170A KR20020000170A (ko) 2002-01-04
KR100732692B1 true KR100732692B1 (ko) 2007-06-27

Family

ID=26878649

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017014085A Expired - Fee Related KR100732692B1 (ko) 1999-05-04 2000-05-01 프로게스테론 수용체 조절인자인 시클로티오카르바메이트유도체

Country Status (24)

Country Link
EP (1) EP1175411B1 (https=)
JP (2) JP4958338B2 (https=)
KR (1) KR100732692B1 (https=)
CN (1) CN1131856C (https=)
AT (1) ATE386729T1 (https=)
AU (1) AU766801B2 (https=)
BG (1) BG65277B1 (https=)
BR (1) BR0010214A (https=)
CA (1) CA2371712C (https=)
CZ (1) CZ20013952A3 (https=)
DE (1) DE60038108T2 (https=)
DK (1) DK1175411T3 (https=)
EA (1) EA004511B1 (https=)
ES (1) ES2301482T3 (https=)
GE (1) GEP20043181B (https=)
HU (1) HUP0203332A3 (https=)
IL (1) IL146298A0 (https=)
MX (1) MXPA01011287A (https=)
NO (1) NO321370B1 (https=)
NZ (1) NZ515353A (https=)
PL (1) PL351083A1 (https=)
SG (1) SG120970A1 (https=)
SK (1) SK15922001A3 (https=)
TR (1) TR200103285T2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE386729T1 (de) * 1999-05-04 2008-03-15 Wyeth Corp Cyclothiocarbamatderivate als progesteron- rezeptormodulatoren
US6407101B1 (en) * 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
ATE409699T1 (de) * 2004-04-08 2008-10-15 Wyeth Corp Verfahren zur minimierung von thioamidverunreinigungen
ATE413398T1 (de) * 2004-04-08 2008-11-15 Wyeth Corp Thioamidderivate als progesteronrezeptormodulatoren
EP1756072A2 (en) * 2004-04-27 2007-02-28 Wyeth Purification of progesterone receptor modulators
CA2562160C (en) * 2004-04-27 2013-05-28 Wyeth Cyanopyrrole containing cyclic carbamate and thiocarbamate biaryls and methods for preparing the same
WO2006014476A1 (en) * 2004-07-07 2006-02-09 Wyeth Cyclic progestin regimens and kits
SI1778710T1 (sl) 2004-08-13 2012-05-31 Wyeth Llc Derivati tanaprogeta metaboliti in njihove uporabe
EP1877059B8 (en) 2005-04-28 2010-05-19 Wyeth a Corporation of the State of Delaware Micronized tanaproget and compostions containing same
JP2008539254A (ja) * 2005-04-28 2008-11-13 ワイス タナプロゲットの精製形態
SI1896034T1 (sl) 2005-04-28 2010-07-30 Wyeth Llc Mikronizirani sestavki tanaprogeta in postopki priprave le-tega
WO2007030153A2 (en) * 2005-04-28 2007-03-15 Wyeth Compositions containing micronized tanaproget
BRPI0610433A2 (pt) * 2005-04-28 2010-11-23 Wyeth Corp forma polimórfica ii de tanaproget, processos para preparar a mesma, e para preparar forma micronizada de um composto, composição farmacêutica, método de preparação de uma composição farmacêutica, e, uso da forma polimórfica ii de tanaproget ou da forma micronizada
CN103989687A (zh) * 2005-06-09 2014-08-20 惠氏公司 含有炔雌醇的tanaproget组合物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0510235A1 (en) * 1991-04-26 1992-10-28 Dong-A Pharm. Co., Ltd. Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same
JPH0510235A (ja) * 1991-07-05 1993-01-19 Nippondenso Co Ltd 内燃機関の点火時期制御装置
WO1995020389A1 (en) * 1994-01-28 1995-08-03 Merck & Co., Inc. Benzoxazinones as inhibitors of hiv reverse transcriptase
WO1996019458A2 (en) * 1994-12-22 1996-06-27 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
WO1998014436A1 (en) * 1996-10-02 1998-04-09 Dupont Pharmaceuticals Company 4,4-disubstituted-1,4-dihydro-2h-3,1-benzoxazin-2-ones useful as hiv reverse transcriptase inhibitors and intermediates and processes for making the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696130A (en) * 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Tricyclic steroid receptor modulator compounds and methods
ATE386729T1 (de) * 1999-05-04 2008-03-15 Wyeth Corp Cyclothiocarbamatderivate als progesteron- rezeptormodulatoren
EP1877059B8 (en) * 2005-04-28 2010-05-19 Wyeth a Corporation of the State of Delaware Micronized tanaproget and compostions containing same
CN103989687A (zh) * 2005-06-09 2014-08-20 惠氏公司 含有炔雌醇的tanaproget组合物

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0510235A1 (en) * 1991-04-26 1992-10-28 Dong-A Pharm. Co., Ltd. Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same
JPH0510235A (ja) * 1991-07-05 1993-01-19 Nippondenso Co Ltd 内燃機関の点火時期制御装置
WO1995020389A1 (en) * 1994-01-28 1995-08-03 Merck & Co., Inc. Benzoxazinones as inhibitors of hiv reverse transcriptase
WO1996019458A2 (en) * 1994-12-22 1996-06-27 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
WO1998014436A1 (en) * 1996-10-02 1998-04-09 Dupont Pharmaceuticals Company 4,4-disubstituted-1,4-dihydro-2h-3,1-benzoxazin-2-ones useful as hiv reverse transcriptase inhibitors and intermediates and processes for making the same

Also Published As

Publication number Publication date
EA004511B1 (ru) 2004-04-29
JP4958338B2 (ja) 2012-06-20
SG120970A1 (en) 2006-04-26
BG106080A (en) 2002-05-31
CA2371712A1 (en) 2000-11-09
JP2012087129A (ja) 2012-05-10
PL351083A1 (en) 2003-03-10
BR0010214A (pt) 2002-02-13
ATE386729T1 (de) 2008-03-15
CN1131856C (zh) 2003-12-24
NZ515353A (en) 2004-03-26
IL146298A0 (en) 2002-07-25
CZ20013952A3 (cs) 2002-05-15
BG65277B1 (bg) 2007-11-30
ES2301482T3 (es) 2008-07-01
JP2002543192A (ja) 2002-12-17
AU4811900A (en) 2000-11-17
EP1175411B1 (en) 2008-02-20
DK1175411T3 (da) 2008-06-09
JP5523430B2 (ja) 2014-06-18
EP1175411A1 (en) 2002-01-30
NO20015381L (no) 2002-01-03
KR20020000170A (ko) 2002-01-04
TR200103285T2 (tr) 2002-02-21
CA2371712C (en) 2009-12-22
EA200101181A1 (ru) 2002-04-25
NO321370B1 (no) 2006-05-02
NO20015381D0 (no) 2001-11-02
DE60038108T2 (de) 2009-02-12
GEP20043181B (en) 2004-02-25
AU766801B2 (en) 2003-10-23
HUP0203332A2 (hu) 2003-01-28
DE60038108D1 (de) 2008-04-03
CN1349516A (zh) 2002-05-15
SK15922001A3 (sk) 2002-09-10
HUP0203332A3 (en) 2004-12-28
MXPA01011287A (es) 2003-07-14

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