AU766801B2 - Cyclothiocarbamate derivatives as progesterone receptor modulators - Google Patents
Cyclothiocarbamate derivatives as progesterone receptor modulators Download PDFInfo
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- AU766801B2 AU766801B2 AU48119/00A AU4811900A AU766801B2 AU 766801 B2 AU766801 B2 AU 766801B2 AU 48119/00 A AU48119/00 A AU 48119/00A AU 4811900 A AU4811900 A AU 4811900A AU 766801 B2 AU766801 B2 AU 766801B2
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- substituted
- alkyl
- dihydro
- dimethyl
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- 239000002379 progesterone receptor modulator Substances 0.000 title description 2
- 229940095745 sex hormone and modulator of the genital system progesterone receptor modulator Drugs 0.000 title description 2
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- 238000011282 treatment Methods 0.000 claims abstract description 34
- 125000005842 heteroatom Chemical group 0.000 claims abstract description 25
- 150000003839 salts Chemical class 0.000 claims abstract description 24
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- 125000003545 alkoxy group Chemical group 0.000 claims abstract description 22
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- PNQBEPDZQUOCNY-UHFFFAOYSA-N trifluoroacetyl chloride Chemical compound FC(F)(F)C(Cl)=O PNQBEPDZQUOCNY-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Detergent Compositions (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
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|---|---|---|---|
| US18301399P | 1999-05-04 | 1999-05-04 | |
| US60/183013 | 1999-05-04 | ||
| US09/552,354 US6436929B1 (en) | 1999-05-04 | 2000-04-19 | Cyclothiocarbamate derivatives as progesterone receptor modulators |
| US09/552354 | 2000-04-19 | ||
| PCT/US2000/011749 WO2000066570A1 (en) | 1999-05-04 | 2000-05-01 | Cyclothiocarbamate derivatives as progesterone receptor modulators |
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| AU4811900A AU4811900A (en) | 2000-11-17 |
| AU766801B2 true AU766801B2 (en) | 2003-10-23 |
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| AU48119/00A Ceased AU766801B2 (en) | 1999-05-04 | 2000-05-01 | Cyclothiocarbamate derivatives as progesterone receptor modulators |
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| KR (1) | KR100732692B1 (https=) |
| CN (1) | CN1131856C (https=) |
| AT (1) | ATE386729T1 (https=) |
| AU (1) | AU766801B2 (https=) |
| BG (1) | BG65277B1 (https=) |
| BR (1) | BR0010214A (https=) |
| CA (1) | CA2371712C (https=) |
| CZ (1) | CZ20013952A3 (https=) |
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| DK (1) | DK1175411T3 (https=) |
| EA (1) | EA004511B1 (https=) |
| ES (1) | ES2301482T3 (https=) |
| GE (1) | GEP20043181B (https=) |
| HU (1) | HUP0203332A3 (https=) |
| IL (1) | IL146298A0 (https=) |
| MX (1) | MXPA01011287A (https=) |
| NO (1) | NO321370B1 (https=) |
| NZ (1) | NZ515353A (https=) |
| PL (1) | PL351083A1 (https=) |
| SG (1) | SG120970A1 (https=) |
| SK (1) | SK15922001A3 (https=) |
| TR (1) | TR200103285T2 (https=) |
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| SG120970A1 (en) * | 1999-05-04 | 2006-04-26 | Ligand Pharm Inc | Cyclothiocarbamate derivatives as progesterone receptor modulators |
| US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
| ES2317223T3 (es) * | 2004-04-08 | 2009-04-16 | Wyeth | Derivados de tioamida como moduladores del receptor de progesterona. |
| JP4950027B2 (ja) * | 2004-04-08 | 2012-06-13 | ワイス・エルエルシー | チオアミド不純物を最小限に抑えるための方法 |
| BRPI0510278A (pt) * | 2004-04-27 | 2007-10-30 | Wyeth Corp | método para produzir compostos, produto, e, composto |
| MXPA06012403A (es) | 2004-04-27 | 2007-01-17 | Wyeth Corp | Purificacion de moduladores de receptor progesterona. |
| US20060009428A1 (en) * | 2004-07-07 | 2006-01-12 | Wyeth | Cyclic progestin regimens and kits |
| MX2007001812A (es) * | 2004-08-13 | 2007-03-26 | Wyeth Corp | Derivados de tanaproget, metabolitos, y usos de los mismos. |
| CN101166532B (zh) | 2005-04-28 | 2011-06-22 | 惠氏公司 | 微粒化的他那普戈特、组合物及其制备方法 |
| CN101166521A (zh) * | 2005-04-28 | 2008-04-23 | 惠氏公司 | 通过湿制粒法制备包含微粒化他那普戈特的组合物 |
| CN101166736B (zh) * | 2005-04-28 | 2013-02-06 | 惠氏公司 | 他那普戈特的多晶型ⅱ |
| AU2006241189B2 (en) * | 2005-04-28 | 2012-01-19 | Wyeth Llc | Purified form of tanaproget |
| MX2007013467A (es) | 2005-04-28 | 2008-01-21 | Wyeth Corp | Tanaproget micronizado y composiciones que contienen el mismo. |
| CA2610767C (en) * | 2005-06-09 | 2014-09-23 | Wyeth | Tanaproget compositions containing ethinyl estradiol |
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| EP0510235A1 (en) * | 1991-04-26 | 1992-10-28 | Dong-A Pharm. Co., Ltd. | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same |
| JPH0510235A (ja) * | 1991-07-05 | 1993-01-19 | Nippondenso Co Ltd | 内燃機関の点火時期制御装置 |
| AU1694295A (en) * | 1994-01-28 | 1995-08-15 | Merck & Co., Inc. | Benzoxazinones as inhibitors of hiv reverse transcriptase |
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| CA2610767C (en) * | 2005-06-09 | 2014-09-23 | Wyeth | Tanaproget compositions containing ethinyl estradiol |
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2000
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2001
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| TC | Change of applicant's name (sec. 104) |
Owner name: LIGAND PHARMACEUTICALS, INC., WYETH Free format text: FORMER NAME: AMERICAN HOME PRODUCTS CORPORATION, LIGAND PHARMACEUTICALS, INC. |
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| FGA | Letters patent sealed or granted (standard patent) |