KR100519580B1 - 분할정제 - Google Patents
분할정제 Download PDFInfo
- Publication number
- KR100519580B1 KR100519580B1 KR10-1999-0011628A KR19990011628A KR100519580B1 KR 100519580 B1 KR100519580 B1 KR 100519580B1 KR 19990011628 A KR19990011628 A KR 19990011628A KR 100519580 B1 KR100519580 B1 KR 100519580B1
- Authority
- KR
- South Korea
- Prior art keywords
- tablet
- divided
- line
- tablets
- edge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 229920003002 synthetic resin Polymers 0.000 description 8
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- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 7
- 239000004743 Polypropylene Substances 0.000 description 6
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 6
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- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 6
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- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 description 3
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- 239000008120 corn starch Substances 0.000 description 3
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- 229910052919 magnesium silicate Inorganic materials 0.000 description 3
- 235000019792 magnesium silicate Nutrition 0.000 description 3
- 235000019359 magnesium stearate Nutrition 0.000 description 3
- ZADYMNAVLSWLEQ-UHFFFAOYSA-N magnesium;oxygen(2-);silicon(4+) Chemical compound [O-2].[O-2].[O-2].[Mg+2].[Si+4] ZADYMNAVLSWLEQ-UHFFFAOYSA-N 0.000 description 3
- 239000006082 mold release agent Substances 0.000 description 3
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- 241000894006 Bacteria Species 0.000 description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 2
- 229920002785 Croscarmellose sodium Polymers 0.000 description 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 229920002433 Vinyl chloride-vinyl acetate copolymer Polymers 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- 239000000556 agonist Substances 0.000 description 2
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 description 2
- 239000008116 calcium stearate Substances 0.000 description 2
- 235000013539 calcium stearate Nutrition 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 2
- 229940105329 carboxymethylcellulose Drugs 0.000 description 2
- 238000000748 compression moulding Methods 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 229960001681 croscarmellose sodium Drugs 0.000 description 2
- 229960000913 crospovidone Drugs 0.000 description 2
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000004570 mortar (masonry) Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 description 2
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000004513 sizing Methods 0.000 description 2
- 239000011343 solid material Substances 0.000 description 2
- 238000010025 steaming Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 244000215068 Acacia senegal Species 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 229920003114 HPC-L Polymers 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 239000004610 Internal Lubricant Substances 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
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- 230000000202 analgesic effect Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
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- 239000000428 dust Substances 0.000 description 1
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- 238000009778 extrusion testing Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000008172 hydrogenated vegetable oil Substances 0.000 description 1
- 239000001341 hydroxy propyl starch Substances 0.000 description 1
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- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- 235000013828 hydroxypropyl starch Nutrition 0.000 description 1
- 239000005555 hypertensive agent Substances 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229940127249 oral antibiotic Drugs 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920001225 polyester resin Polymers 0.000 description 1
- 239000004645 polyester resin Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 229920005992 thermoplastic resin Polymers 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0007—Pill breaking or crushing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
- B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
- B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D2575/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D2575/3209—Details
- B65D2575/3218—Details with special means for gaining access to the contents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Composite Materials (AREA)
- Mechanical Engineering (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packages (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP98-91746 | 1998-04-03 | ||
| JP9174698 | 1998-04-03 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020040052194A Division KR20040070128A (ko) | 1998-04-03 | 2004-07-06 | 프레스-스루 팩 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR19990082890A KR19990082890A (ko) | 1999-11-25 |
| KR100519580B1 true KR100519580B1 (ko) | 2005-10-07 |
Family
ID=14035108
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR10-1999-0011628A Expired - Lifetime KR100519580B1 (ko) | 1998-04-03 | 1999-04-02 | 분할정제 |
| KR1020040052194A Ceased KR20040070128A (ko) | 1998-04-03 | 2004-07-06 | 프레스-스루 팩 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020040052194A Ceased KR20040070128A (ko) | 1998-04-03 | 2004-07-06 | 프레스-스루 팩 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6342248B1 (enExample) |
| EP (1) | EP0947188B1 (enExample) |
| JP (2) | JP3839065B2 (enExample) |
| KR (2) | KR100519580B1 (enExample) |
| CN (1) | CN1241553C (enExample) |
| AT (1) | ATE387905T1 (enExample) |
| AU (1) | AU764526C (enExample) |
| CA (1) | CA2268215C (enExample) |
| DE (1) | DE69938268T2 (enExample) |
| ES (1) | ES2302364T3 (enExample) |
| ID (1) | ID22360A (enExample) |
| IN (1) | IN190906B (enExample) |
| MY (1) | MY121786A (enExample) |
| SG (1) | SG70678A1 (enExample) |
| TW (1) | TW479045B (enExample) |
| WO (1) | WO1999051207A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002028222A (ja) * | 2000-04-28 | 2002-01-29 | Kyowa Hakko Kogyo Co Ltd | 錠剤分割器具、錠剤及びプレススルーパック |
| ITMI20012481A1 (it) | 2001-11-23 | 2003-05-23 | Univ Parma | Sistemi modulari per il rilascio controllato di sostanza a controllo spaziale e temporale |
| US20030215502A1 (en) * | 2002-03-20 | 2003-11-20 | Elan Pharma International Limited | Fast dissolving dosage forms having reduced friability |
| JP4652662B2 (ja) * | 2002-12-13 | 2011-03-16 | 田辺三菱製薬株式会社 | 分割錠剤 |
| TW200502000A (en) * | 2003-03-28 | 2005-01-16 | Kyowa Hakko Kogyo Kk | Dividing tablet |
| JP2005145821A (ja) * | 2003-11-11 | 2005-06-09 | Kao Corp | 打錠製剤 |
| US7820198B2 (en) * | 2004-10-19 | 2010-10-26 | Arch Chemicals, Inc. | Pool chemical tablet |
| PT1867324T (pt) * | 2005-03-31 | 2016-08-29 | Takeda Pharmaceuticals Co | Comprimido¿ |
| FR2885051B1 (fr) * | 2005-04-28 | 2008-07-25 | So Ge Val Sa | Comprime notamment comprime veterinaire secable en particulier pour chiens ou chats |
| US7985419B1 (en) * | 2006-12-22 | 2011-07-26 | Watson Laboratories, Inc. | Divisible tablet and associated methods |
| FR2928836B1 (fr) * | 2008-03-21 | 2011-08-26 | Servier Lab | Forme galenique secable permettant une liberation modifiee du principe actif |
| AR072437A1 (es) * | 2008-07-01 | 2010-08-25 | Otsuka Pharma Co Ltd | Un comprimido de medicamento |
| AR076529A1 (es) * | 2008-09-16 | 2011-06-22 | Takeda Pharmaceutical | Comprimido ranurado recubierto de pelicula |
| USD672029S1 (en) * | 2010-12-15 | 2012-12-04 | Otsuka Pharmaceutical Co., Ltd. | Tablet |
| USD672030S1 (en) * | 2010-12-15 | 2012-12-04 | Otsuka Pharmaceutical Co., Ltd. | Tablet |
| AU337556S (en) * | 2010-12-15 | 2011-07-11 | Otsuka Pharma Co Ltd | Tablet |
| US10245215B2 (en) * | 2014-03-21 | 2019-04-02 | Tyson Triplett | Pill cutting and storage device |
| US20190076365A1 (en) * | 2016-03-15 | 2019-03-14 | Astellas Pharma Inc. | Tablet |
| CN107041845B (zh) * | 2017-05-05 | 2023-05-23 | 杨超翔 | 儿童给药装置及方法 |
| CN107379617B (zh) * | 2017-09-14 | 2019-07-26 | 南京乐锐斯医药科技有限公司 | 一种药片的加工工艺 |
| US10786434B2 (en) * | 2018-12-18 | 2020-09-29 | Erin Keeley Casner | Tablet splitter |
| CN112823639A (zh) * | 2019-11-20 | 2021-05-21 | 李国龙 | 食品结构及其制造方法 |
| USD933847S1 (en) | 2020-01-17 | 2021-10-19 | Studio 010 Inc. | Pill splitter |
| US11672735B2 (en) | 2020-01-17 | 2023-06-13 | Studio 010 Inc. | Pill splitter |
| USD941985S1 (en) * | 2020-04-07 | 2022-01-25 | Nutramax Laboratories, Inc. | Dietary supplement |
| USD941457S1 (en) | 2020-04-07 | 2022-01-18 | Nutramax Laboratories, Inc. | Dietary supplement |
| JP7453859B2 (ja) * | 2020-06-22 | 2024-03-21 | 東和薬品株式会社 | エスシタロプラム錠剤 |
| USD941458S1 (en) | 2020-08-11 | 2022-01-18 | Nutramax Laboratories, Inc. | Dietary supplement |
| USD942609S1 (en) | 2020-08-11 | 2022-02-01 | Nutramax Laboratories, Inc. | Dietary supplement |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB993291A (en) * | 1961-12-06 | 1965-05-26 | Thomas Lee Cooper | Tablets, pills, pellets and the like |
| GB1368574A (en) | 1971-02-12 | 1974-10-02 | Ives Lab Inc | Divisible tablet |
| GB1387643A (en) * | 1971-03-16 | 1975-03-19 | Ives Lab Inc | Divisible tablet |
| US3921805A (en) * | 1972-10-10 | 1975-11-25 | Newton L Compere | Rupturable blister pill package with safety backing |
| US4353887A (en) * | 1979-08-16 | 1982-10-12 | Ciba-Geigy Corporation | Divisible tablet having controlled and delayed release of the active substance |
| JPS61287568A (ja) * | 1985-05-02 | 1986-12-17 | 東洋アルミニウム株式会社 | プレススル−パツク |
| GB8514089D0 (en) | 1985-06-04 | 1985-07-10 | Sandoz Ltd | Pharmaceutical tablet |
| US4824677A (en) * | 1986-12-18 | 1989-04-25 | The Unjohn Company | Grooved tablet for fractional dosing of sustained release medication |
| NZ255541A (en) * | 1992-09-09 | 1996-05-28 | Fisons Plc | Blister package for medicament-containing capsules with an aperture for dispensing the medicament; the package base has a sealing means to seal the capsule aperture |
| JPH07149367A (ja) | 1993-11-20 | 1995-06-13 | Dainippon Printing Co Ltd | プレススルーパック |
| JPH07179333A (ja) * | 1993-12-21 | 1995-07-18 | Kikusui Seisakusho:Kk | 錠 剤 |
| JPH07257639A (ja) * | 1994-03-22 | 1995-10-09 | Dainippon Printing Co Ltd | プレススルーパック |
| JP3015677B2 (ja) * | 1994-08-10 | 2000-03-06 | ファイザー製薬株式会社 | フィルムコーティングを施した分割錠剤 |
| JP3670710B2 (ja) * | 1995-04-04 | 2005-07-13 | 協和醗酵工業株式会社 | 割溝付き錠剤および割溝形成凸部付き杵 |
| JPH08277217A (ja) * | 1995-04-05 | 1996-10-22 | Sumitomo Pharmaceut Co Ltd | 分割性錠剤 |
| JP3553220B2 (ja) * | 1995-08-17 | 2004-08-11 | ダイセル化学工業株式会社 | 封緘性フィルムおよびその製造方法 |
| DE29617001U1 (de) * | 1996-09-30 | 1996-11-21 | Azupharma GmbH, 70839 Gerlingen | Tablette in Herzform |
| EP1057743B1 (en) * | 1997-10-02 | 2005-12-28 | Kyowa Hakko Kogyo Co., Ltd. | Press-through pack and methods of taking-out and of dividing tablets |
| JP5367212B2 (ja) * | 1998-04-03 | 2013-12-11 | 協和発酵キリン株式会社 | 錠剤の分割方法、分割容易化方法および分割容易な錠剤の製造方法 |
-
1999
- 1999-04-01 JP JP53819499A patent/JP3839065B2/ja not_active Expired - Lifetime
- 1999-04-01 AT AT99106101T patent/ATE387905T1/de not_active IP Right Cessation
- 1999-04-01 IN IN383MA1999 patent/IN190906B/en unknown
- 1999-04-01 DE DE69938268T patent/DE69938268T2/de not_active Expired - Lifetime
- 1999-04-01 EP EP99106101A patent/EP0947188B1/en not_active Expired - Lifetime
- 1999-04-01 ES ES99106101T patent/ES2302364T3/es not_active Expired - Lifetime
- 1999-04-01 CA CA002268215A patent/CA2268215C/en not_active Expired - Fee Related
- 1999-04-01 WO PCT/JP1999/001769 patent/WO1999051207A1/ja not_active Ceased
- 1999-04-01 SG SG1999001626A patent/SG70678A1/en unknown
- 1999-04-02 TW TW088105293A patent/TW479045B/zh not_active IP Right Cessation
- 1999-04-02 US US09/285,062 patent/US6342248B1/en not_active Expired - Lifetime
- 1999-04-02 KR KR10-1999-0011628A patent/KR100519580B1/ko not_active Expired - Lifetime
- 1999-04-02 MY MYPI99001270A patent/MY121786A/en unknown
- 1999-04-02 CN CN99104789.3A patent/CN1241553C/zh not_active Expired - Lifetime
- 1999-04-05 ID IDP990305A patent/ID22360A/id unknown
- 1999-04-06 AU AU23606/99A patent/AU764526C/en not_active Ceased
-
2004
- 2004-07-06 KR KR1020040052194A patent/KR20040070128A/ko not_active Ceased
-
2009
- 2009-09-24 JP JP2009218646A patent/JP5219092B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69938268T2 (de) | 2009-04-30 |
| US6342248B1 (en) | 2002-01-29 |
| KR20040070128A (ko) | 2004-08-06 |
| AU764526C (en) | 2004-03-25 |
| IN190906B (enExample) | 2003-08-30 |
| JP2009292845A (ja) | 2009-12-17 |
| MY121786A (en) | 2006-02-28 |
| CN1231887A (zh) | 1999-10-20 |
| CN1241553C (zh) | 2006-02-15 |
| WO1999051207A1 (fr) | 1999-10-14 |
| JP5219092B2 (ja) | 2013-06-26 |
| ATE387905T1 (de) | 2008-03-15 |
| EP0947188A2 (en) | 1999-10-06 |
| KR19990082890A (ko) | 1999-11-25 |
| CA2268215A1 (en) | 1999-10-03 |
| JP3839065B2 (ja) | 2006-11-01 |
| ES2302364T3 (es) | 2008-07-01 |
| EP0947188A3 (en) | 2000-05-31 |
| ID22360A (id) | 1999-10-07 |
| AU764526B2 (en) | 2003-08-21 |
| DE69938268D1 (de) | 2008-04-17 |
| AU2360699A (en) | 1999-10-14 |
| EP0947188B1 (en) | 2008-03-05 |
| CA2268215C (en) | 2009-01-06 |
| TW479045B (en) | 2002-03-11 |
| SG70678A1 (en) | 2000-02-22 |
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