KR100512673B1 - 조혈세포계내유도된어팝토시스를치료하기위한플루피르틴의조성물 - Google Patents

조혈세포계내유도된어팝토시스를치료하기위한플루피르틴의조성물 Download PDF

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Publication number
KR100512673B1
KR100512673B1 KR10-1998-0703376A KR19980703376A KR100512673B1 KR 100512673 B1 KR100512673 B1 KR 100512673B1 KR 19980703376 A KR19980703376 A KR 19980703376A KR 100512673 B1 KR100512673 B1 KR 100512673B1
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KR
South Korea
Prior art keywords
cells
apoptosis
flupyrutin
flupyritin
cell
Prior art date
Application number
KR10-1998-0703376A
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English (en)
Korean (ko)
Other versions
KR19990067366A (ko
Inventor
가브리엘라 페르간데
게. 뮐러 베르너 에.
Original Assignee
비아트리스 게엠베하 앤드 코. 카게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of KR19990067366A publication Critical patent/KR19990067366A/ko
Application granted granted Critical
Publication of KR100512673B1 publication Critical patent/KR100512673B1/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR10-1998-0703376A 1995-11-07 1996-10-23 조혈세포계내유도된어팝토시스를치료하기위한플루피르틴의조성물 KR100512673B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19541405.5 1995-11-07
DE19541405A DE19541405A1 (de) 1995-11-07 1995-11-07 Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen
PCT/DE1996/002009 WO1997017072A2 (fr) 1995-11-07 1996-10-23 Utilisation de flupirtine pour la prophylaxie et le traitement de maladies associees a une alteration du systeme cellulaire hematopoietique

Publications (2)

Publication Number Publication Date
KR19990067366A KR19990067366A (ko) 1999-08-16
KR100512673B1 true KR100512673B1 (ko) 2005-12-09

Family

ID=7776799

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-1998-0703376A KR100512673B1 (ko) 1995-11-07 1996-10-23 조혈세포계내유도된어팝토시스를치료하기위한플루피르틴의조성물

Country Status (27)

Country Link
US (2) US6034111A (fr)
EP (1) EP0859613B1 (fr)
JP (1) JPH11514652A (fr)
KR (1) KR100512673B1 (fr)
CN (1) CN1116037C (fr)
AT (1) ATE316789T1 (fr)
AU (1) AU711207B2 (fr)
BG (1) BG63149B1 (fr)
BR (1) BR9611588A (fr)
CA (1) CA2189705C (fr)
CZ (1) CZ298115B6 (fr)
DE (2) DE19541405A1 (fr)
DK (1) DK0859613T3 (fr)
ES (1) ES2257755T3 (fr)
HK (1) HK1016508A1 (fr)
HU (1) HU225742B1 (fr)
MX (1) MX9803610A (fr)
NO (1) NO315074B1 (fr)
NZ (1) NZ330414A (fr)
PL (1) PL186537B1 (fr)
PT (1) PT859613E (fr)
RU (1) RU2200555C2 (fr)
SK (1) SK284601B6 (fr)
TW (1) TW393317B (fr)
UA (1) UA51682C2 (fr)
WO (1) WO1997017072A2 (fr)
ZA (1) ZA968783B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20120055619A (ko) * 2009-08-07 2012-05-31 스와겔로크 컴패니 저진공 하에서의 저온 침탄

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19625582A1 (de) * 1996-06-27 1998-01-02 Asta Medica Ag Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen die mit einer unphysiologisch hohen Zellsterberate einhergehen
US6821995B1 (en) 1999-12-01 2004-11-23 Duke University Method of treating batten disease
DE10327674A1 (de) 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injizierbare Darreichungsform von Flupirtin
EP1688141A1 (fr) * 2005-01-31 2006-08-09 elbion AG Utilisation de flupirtine pour le traitement de la vessie hyperactive et des maladies associées et pour le traitement du syndrome du colon irritable
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
DE102009023162B4 (de) * 2009-05-29 2011-07-07 Corden PharmaChem GmbH, 68305 Verfahren zur Herstellung von Flupirtin
DE102010030053A1 (de) 2010-06-14 2011-12-15 Awd.Pharma Gmbh & Co.Kg Injizierbare Darreichungsform von Flupirtin
WO2013127539A2 (fr) * 2012-03-02 2013-09-06 Meda Pharma Gmbh & Co. Kg Formulations pharmaceutiques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN172468B (fr) * 1990-07-14 1993-08-14 Asta Medica Ag
DE4327516A1 (de) * 1993-08-17 1995-02-23 Asta Medica Ag Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Society for Neuroscience Abstracts, Vol 20 pt 1, 1994 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20120055619A (ko) * 2009-08-07 2012-05-31 스와겔로크 컴패니 저진공 하에서의 저온 침탄

Also Published As

Publication number Publication date
NO315074B1 (no) 2003-07-07
CN1116037C (zh) 2003-07-30
NO981898L (no) 1998-04-27
WO1997017072A2 (fr) 1997-05-15
CZ298115B6 (cs) 2007-06-27
US6034111A (en) 2000-03-07
BR9611588A (pt) 1999-04-06
HU225742B1 (en) 2007-07-30
BG63149B1 (bg) 2001-05-31
DE19541405A1 (de) 1997-05-15
EP0859613B1 (fr) 2006-02-01
US6034112A (en) 2000-03-07
PT859613E (pt) 2006-06-30
CA2189705A1 (fr) 1997-05-08
JPH11514652A (ja) 1999-12-14
HUP9901659A2 (hu) 1999-09-28
NZ330414A (en) 1999-10-28
DE59611327D1 (de) 2006-04-13
ZA968783B (en) 1997-05-27
BG102404A (en) 1998-12-30
EP0859613A2 (fr) 1998-08-26
SK284601B6 (sk) 2005-07-01
PL186537B1 (pl) 2004-01-30
ES2257755T3 (es) 2006-08-01
WO1997017072A3 (fr) 1997-07-24
TW393317B (en) 2000-06-11
CZ128398A3 (cs) 1998-09-16
PL326629A1 (en) 1998-10-12
SK58698A3 (en) 1998-09-09
RU2200555C2 (ru) 2003-03-20
DK0859613T3 (da) 2006-06-06
HK1016508A1 (en) 1999-11-05
AU1716597A (en) 1997-05-29
KR19990067366A (ko) 1999-08-16
ATE316789T1 (de) 2006-02-15
NO981898D0 (no) 1998-04-27
HUP9901659A3 (en) 2001-04-28
AU711207B2 (en) 1999-10-07
CN1201391A (zh) 1998-12-09
UA51682C2 (uk) 2002-12-16
MX9803610A (es) 1998-09-30
CA2189705C (fr) 2005-08-09

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