HUP9901659A2 - Flupirtin alkalmazása a hematopoetikus sejtrendszer károsodásával kapcsolatos megbetegedések megelőzésére és gyógyítására alkalmas gyógyszerkészítmény előállítására - Google Patents
Flupirtin alkalmazása a hematopoetikus sejtrendszer károsodásával kapcsolatos megbetegedések megelőzésére és gyógyítására alkalmas gyógyszerkészítmény előállításáraInfo
- Publication number
- HUP9901659A2 HUP9901659A2 HU9901659A HUP9901659A HUP9901659A2 HU P9901659 A2 HUP9901659 A2 HU P9901659A2 HU 9901659 A HU9901659 A HU 9901659A HU P9901659 A HUP9901659 A HU P9901659A HU P9901659 A2 HUP9901659 A2 HU P9901659A2
- Authority
- HU
- Hungary
- Prior art keywords
- diseases
- damage
- treatment
- cell system
- flupirtin
- Prior art date
Links
- JUUFBMODXQKSTD-UHFFFAOYSA-N N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester Chemical compound N1=C(N)C(NC(=O)OCC)=CC=C1NCC1=CC=C(F)C=C1 JUUFBMODXQKSTD-UHFFFAOYSA-N 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 210000004524 haematopoietic cell Anatomy 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960003667 flupirtine Drugs 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polyurethanes Or Polyureas (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
A találmány tárgyát flűpirtin hatóanyag vagy annak gyógyszerészetilegfelhasználható sóinak alkalmazása képezi őlyan betegségek kezeléséreszőlgáló gyógyszerkészítmény előállítására, amelyek a hematőpőetikűssejtrendszer kárősításával kapcsőlatősak. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19541405A DE19541405A1 (de) | 1995-11-07 | 1995-11-07 | Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen |
PCT/DE1996/002009 WO1997017072A2 (de) | 1995-11-07 | 1996-10-23 | Verwendung von flupirtin zur prophylaxe und therapie von erkrankungen, die mit einer beeinträchtigung des hämatopoetischen zellsystems einhergehen |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP9901659A2 true HUP9901659A2 (hu) | 1999-09-28 |
HUP9901659A3 HUP9901659A3 (en) | 2001-04-28 |
HU225742B1 HU225742B1 (en) | 2007-07-30 |
Family
ID=7776799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9901659A HU225742B1 (en) | 1995-11-07 | 1996-10-23 | Use of flupirtin for producing pharmaceutical compositions suitable for the prevention and treatment of diseases which are associated with damage to the haemopoietic cell system |
Country Status (27)
Country | Link |
---|---|
US (2) | US6034111A (hu) |
EP (1) | EP0859613B1 (hu) |
JP (1) | JPH11514652A (hu) |
KR (1) | KR100512673B1 (hu) |
CN (1) | CN1116037C (hu) |
AT (1) | ATE316789T1 (hu) |
AU (1) | AU711207B2 (hu) |
BG (1) | BG63149B1 (hu) |
BR (1) | BR9611588A (hu) |
CA (1) | CA2189705C (hu) |
CZ (1) | CZ298115B6 (hu) |
DE (2) | DE19541405A1 (hu) |
DK (1) | DK0859613T3 (hu) |
ES (1) | ES2257755T3 (hu) |
HK (1) | HK1016508A1 (hu) |
HU (1) | HU225742B1 (hu) |
MX (1) | MX9803610A (hu) |
NO (1) | NO315074B1 (hu) |
NZ (1) | NZ330414A (hu) |
PL (1) | PL186537B1 (hu) |
PT (1) | PT859613E (hu) |
RU (1) | RU2200555C2 (hu) |
SK (1) | SK284601B6 (hu) |
TW (1) | TW393317B (hu) |
UA (1) | UA51682C2 (hu) |
WO (1) | WO1997017072A2 (hu) |
ZA (1) | ZA968783B (hu) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19625582A1 (de) * | 1996-06-27 | 1998-01-02 | Asta Medica Ag | Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen die mit einer unphysiologisch hohen Zellsterberate einhergehen |
US6821995B1 (en) | 1999-12-01 | 2004-11-23 | Duke University | Method of treating batten disease |
DE10327674A1 (de) | 2003-06-20 | 2005-01-05 | Awd.Pharma Gmbh & Co. Kg | Injizierbare Darreichungsform von Flupirtin |
EP1688141A1 (en) * | 2005-01-31 | 2006-08-09 | elbion AG | The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome |
US20080279930A1 (en) * | 2007-05-07 | 2008-11-13 | Bernd Terhaag | Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof |
DE102009023162B4 (de) * | 2009-05-29 | 2011-07-07 | Corden PharmaChem GmbH, 68305 | Verfahren zur Herstellung von Flupirtin |
EP2462253B1 (en) * | 2009-08-07 | 2021-04-07 | Swagelok Company | Low temperature carburization under soft vacuum |
DE102010030053A1 (de) | 2010-06-14 | 2011-12-15 | Awd.Pharma Gmbh & Co.Kg | Injizierbare Darreichungsform von Flupirtin |
MX2014010460A (es) * | 2012-03-02 | 2014-10-13 | Meda Pharma Gmbh & Co Kg | Formulaciones farmaceuticas que contienen flupirtina. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN172468B (hu) * | 1990-07-14 | 1993-08-14 | Asta Medica Ag | |
DE4327516A1 (de) * | 1993-08-17 | 1995-02-23 | Asta Medica Ag | Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin |
-
1995
- 1995-11-07 DE DE19541405A patent/DE19541405A1/de not_active Ceased
-
1996
- 1996-10-18 ZA ZA968783A patent/ZA968783B/xx unknown
- 1996-10-23 JP JP9517734A patent/JPH11514652A/ja active Pending
- 1996-10-23 DE DE59611327T patent/DE59611327D1/de not_active Expired - Lifetime
- 1996-10-23 BR BR9611588A patent/BR9611588A/pt not_active Application Discontinuation
- 1996-10-23 RU RU98111152/14A patent/RU2200555C2/ru not_active IP Right Cessation
- 1996-10-23 KR KR10-1998-0703376A patent/KR100512673B1/ko not_active IP Right Cessation
- 1996-10-23 ES ES96945822T patent/ES2257755T3/es not_active Expired - Lifetime
- 1996-10-23 PT PT96945822T patent/PT859613E/pt unknown
- 1996-10-23 WO PCT/DE1996/002009 patent/WO1997017072A2/de active IP Right Grant
- 1996-10-23 CN CN96198131A patent/CN1116037C/zh not_active Expired - Fee Related
- 1996-10-23 CZ CZ0128398A patent/CZ298115B6/cs not_active IP Right Cessation
- 1996-10-23 AT AT96945822T patent/ATE316789T1/de active
- 1996-10-23 PL PL96326629A patent/PL186537B1/pl not_active IP Right Cessation
- 1996-10-23 DK DK96945822T patent/DK0859613T3/da active
- 1996-10-23 UA UA98062946A patent/UA51682C2/uk unknown
- 1996-10-23 SK SK586-98A patent/SK284601B6/sk not_active IP Right Cessation
- 1996-10-23 HU HU9901659A patent/HU225742B1/hu not_active IP Right Cessation
- 1996-10-23 EP EP96945822A patent/EP0859613B1/de not_active Expired - Lifetime
- 1996-10-23 NZ NZ330414A patent/NZ330414A/en unknown
- 1996-10-23 AU AU17165/97A patent/AU711207B2/en not_active Ceased
- 1996-11-04 TW TW085113437A patent/TW393317B/zh not_active IP Right Cessation
- 1996-11-06 CA CA002189705A patent/CA2189705C/en not_active Expired - Fee Related
- 1996-11-07 US US08/744,953 patent/US6034111A/en not_active Expired - Lifetime
-
1998
- 1998-04-16 US US09/061,099 patent/US6034112A/en not_active Expired - Lifetime
- 1998-04-24 BG BG102404A patent/BG63149B1/bg unknown
- 1998-04-27 NO NO19981898A patent/NO315074B1/no not_active IP Right Cessation
- 1998-05-07 MX MX9803610A patent/MX9803610A/es not_active IP Right Cessation
-
1999
- 1999-04-21 HK HK99101726A patent/HK1016508A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
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HC9A | Change of name, address |
Owner name: MEDA PHARMA GMBH & CO. KG, DE Free format text: FORMER OWNER(S): ASTA MEDICA AG., DE; ASTA MEDICA HEALTH PRODUCTS GMBH & CO. KG, DE; VIATRIS GMBH & CO. KG, DE; VIATRIS GMBH & CO. KG, DE |
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MM4A | Lapse of definitive patent protection due to non-payment of fees |