KR100250700B1 - 안정화된 레티노이드 함유 피부 보호용 조성물 - Google Patents

안정화된 레티노이드 함유 피부 보호용 조성물 Download PDF

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Publication number
KR100250700B1
KR100250700B1 KR1019930700583A KR930700583A KR100250700B1 KR 100250700 B1 KR100250700 B1 KR 100250700B1 KR 1019930700583 A KR1019930700583 A KR 1019930700583A KR 930700583 A KR930700583 A KR 930700583A KR 100250700 B1 KR100250700 B1 KR 100250700B1
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KR
South Korea
Prior art keywords
composition
oil
antioxidant
water
acid
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1019930700583A
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English (en)
Korean (ko)
Inventor
이. 클럼 찰스
씨. 티. 왕 요나스
Original Assignee
차알스 제이. 메츠
존슨 앤드 존슨 컨수머 컴퍼니즈 인코포레이티드
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Application filed by 차알스 제이. 메츠, 존슨 앤드 존슨 컨수머 컴퍼니즈 인코포레이티드 filed Critical 차알스 제이. 메츠
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/51—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019930700583A 1991-06-27 1991-06-28 안정화된 레티노이드 함유 피부 보호용 조성물 Expired - Lifetime KR100250700B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71926491A 1991-06-27 1991-06-27
US7/719,264 1991-06-27
PCT/US1991/004471 WO1993000085A1 (en) 1991-06-27 1991-06-28 Stabilized retinoid-containing skin care compositions

Publications (1)

Publication Number Publication Date
KR100250700B1 true KR100250700B1 (ko) 2000-07-01

Family

ID=24889399

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930700583A Expired - Lifetime KR100250700B1 (ko) 1991-06-27 1991-06-28 안정화된 레티노이드 함유 피부 보호용 조성물

Country Status (22)

Country Link
EP (1) EP0549592B2 (cg-RX-API-DMAC7.html)
JP (2) JP3435510B2 (cg-RX-API-DMAC7.html)
KR (1) KR100250700B1 (cg-RX-API-DMAC7.html)
AU (1) AU664973B2 (cg-RX-API-DMAC7.html)
BR (1) BR9106891A (cg-RX-API-DMAC7.html)
CA (1) CA2090104C (cg-RX-API-DMAC7.html)
CO (1) CO4130180A1 (cg-RX-API-DMAC7.html)
DE (1) DE69130020T2 (cg-RX-API-DMAC7.html)
EG (1) EG19852A (cg-RX-API-DMAC7.html)
ES (1) ES2120417T5 (cg-RX-API-DMAC7.html)
FI (2) FI930887A0 (cg-RX-API-DMAC7.html)
MA (1) MA22240A1 (cg-RX-API-DMAC7.html)
MX (1) MX187577B (cg-RX-API-DMAC7.html)
MY (2) MY131215A (cg-RX-API-DMAC7.html)
NO (1) NO304405B1 (cg-RX-API-DMAC7.html)
NZ (2) NZ239051A (cg-RX-API-DMAC7.html)
PH (1) PH31832A (cg-RX-API-DMAC7.html)
PT (1) PT98512B (cg-RX-API-DMAC7.html)
SG (1) SG66224A1 (cg-RX-API-DMAC7.html)
TW (1) TW203009B (cg-RX-API-DMAC7.html)
WO (1) WO1993000085A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA915285B (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100355892B1 (ko) * 2000-01-06 2002-10-12 주식회사 코리아나화장품 레티놀과 테트라디부틸 펜타에리스리틸히드록시히드로신나메이트를 함유하는 화장료 조성물

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US5559149A (en) 1990-01-29 1996-09-24 Johnson & Johnson Consumer Products, Inc. Skin care compositions containing retinoids
ES2221921T3 (es) * 1992-07-13 2005-01-16 Shiseido Company, Ltd. Composicion para preparacion dermatologica.
JPH0632722A (ja) * 1992-07-13 1994-02-08 Shiseido Co Ltd 皮膚外用剤
GR1002207B (en) * 1992-08-06 1996-03-27 Johnson & Johnson Consumer Skin care compositions containing imidazoles.
GB9223235D0 (en) * 1992-11-05 1992-12-16 Unilever Plc Cosmetic composition
FR2714595B1 (fr) * 1993-12-30 1996-02-02 Oreal Emulsion eau dans huile contenant du rétinol, son utilisation et son conditionnement.
FR2717686B1 (fr) * 1994-03-22 1996-06-28 Fabre Pierre Cosmetique Composition dermo-cosmétologique et procédé de préparation.
US5976555A (en) * 1994-09-07 1999-11-02 Johnson & Johnson Consumer Products, Inc. Topical oil-in-water emulsions containing retinoids
US6461622B2 (en) * 1994-09-07 2002-10-08 Johnson & Johnson Consumer Companies, Inc. Topical compositions
AU1128997A (en) * 1995-12-11 1997-07-03 Procter & Gamble Company, The Topical retinoid composition
US5851538A (en) * 1995-12-29 1998-12-22 Advanced Polymer Systems, Inc. Retinoid formulations in porous microspheres for reduced irritation and enhanced stability
AR006049A1 (es) 1996-03-01 1999-07-21 Johnson & Johnson Consumer Una emulsion de aceite en agua
US5744148A (en) * 1996-09-20 1998-04-28 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Stabilization of an unstable retinoid in oil-in-water emulsions for skin care compositions
USH2043H1 (en) 1997-05-23 2002-08-06 The Procter & Gamble Company Skin care compositions
DE19745506A1 (de) * 1997-10-15 1999-04-22 Basf Ag Verwendung von Ascorbyl-2-phosphorsäureestern zur Stabilisierung von Vitamin A und/oder Vitamin A-Derivaten in kosmetischen und pharmazeutischen Zubereitung
US6228894B1 (en) * 1998-04-17 2001-05-08 Enhanced Derm Technologies, Inc. Softgel-compatible composition containing retinol
US5891470A (en) * 1998-04-17 1999-04-06 Advanced Polymer Systems, Inc. Softgel formulation containing retinol
US6207717B1 (en) 1999-01-12 2001-03-27 Dow Corning Corporation Entrapment of vitamins with an elastomeric silicone polyether
IN2000KO00299A (cg-RX-API-DMAC7.html) * 1999-05-28 2005-11-18 Johnson & Johnson Consumer
DE10048125A1 (de) * 2000-09-28 2002-04-18 Beiersdorf Ag Zubereitungen von Emulsionstyp W/O mit erhöhtem Wassergehalt, mit mittelpolaren und/oder unpolaren Lipiden und einem oder mehreren grenzflächenaktiven Polyethern vom Typ A-O-B-O-A
DE10048366A1 (de) * 2000-09-29 2002-04-11 Beiersdorf Ag Zubereitungen vom Emulsionstyp W/O mit erhöhtem Wassergehalt, mit mittelpolaren und/oder unpolaren Lipiden und einem oder mehreren grenzflächenaktiven Polyethern vom Typ A-O-B-O-A sowie mit mindestens einer Substanz, gewählt aus der Gruppe der kationischen Polymere
DE10048427A1 (de) * 2000-09-29 2002-04-11 Beiersdorf Ag Zubereitungen vom Emulsionstyp W/O mit erhöhtem Wassergehalt, mit mittelpolaren und/oder unpolaren Lipiden und einem oder mehreren grenzflächenaktiven Polyet hern vom Typ A-O-B-O-A sowie mindestens einer Substanz gewählt aus der Gruppe der anionischen und oder amphoteren Polymere
DE10048429A1 (de) * 2000-09-29 2002-04-11 Beiersdorf Ag Zubereitungen vom Emulsionstyp W/O mit erhöhtem Wassergehalt, mit mittelpolaren und/oder unpolaren Lipiden und einem oder mehreren grenzflächenaktiven Polyethern von Typ A-O-B-O-A sowie einer Substanz gewählt aus der Gruppe der nichtionischen Polymere
IL156411A0 (en) 2000-12-15 2004-01-04 Franke Patrick Hypoallergenic and non-irritant skin care formulations
DE10233740A1 (de) * 2002-07-24 2004-02-05 Basf Ag Retinoid-haltige Zubereitungen
US20060140890A1 (en) * 2002-10-11 2006-06-29 Atsushi Miida Oily solid cosmetic and method for production thereof
JP4119296B2 (ja) * 2003-04-14 2008-07-16 株式会社コーセー 化粧料
DE102004003478A1 (de) * 2004-01-22 2005-08-18 Basf Ag Retinoid-haltige Zubereitungen
JP2006045080A (ja) * 2004-08-02 2006-02-16 Pola Chem Ind Inc 医薬部外品に好適な皮膚外用剤
FR2894465B1 (fr) 2005-12-14 2010-09-10 Fabre Pierre Dermo Cosmetique Utilisation de composes polyinsatures en tant qu'agents blanchissants
DE102006062568A1 (de) 2006-12-29 2008-07-03 Henkel Kgaa Verbesserte Farbstabilisierung wasserhaltiger kosmetischer und pharmazeutischer Mittel
JP6386713B2 (ja) * 2013-10-03 2018-09-05 国立大学法人千葉大学 脳循環障害の予防剤および／または治療剤
WO2017108902A1 (en) * 2015-12-23 2017-06-29 Novartis Ag Oil-in-water emulsions including retinoic acid
US10493009B2 (en) 2016-12-13 2019-12-03 The Procter & Gamble Company Stable personal care compositions containing a retinoid
FR3104977B1 (fr) 2019-12-20 2023-05-05 Oreal Sérum à base de rétinol
FR3104975B1 (fr) 2019-12-20 2021-12-17 Oreal Composition à base de rétinol
FR3104976B1 (fr) 2019-12-20 2021-12-24 Oreal Composition à base de rétinol
FR3111074B1 (fr) 2020-06-08 2022-07-01 Oreal Composition à base de rétinol
FR3111075B1 (fr) 2020-06-08 2022-12-16 Oreal Composition à base de rétinol

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KR910001221A (ko) * 1989-06-30 1991-01-30 후루다 노리마사 엔진의 흡기장치

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US4603146A (en) * 1984-05-16 1986-07-29 Kligman Albert M Methods for retarding the effects of aging of the skin
US4877805A (en) * 1985-07-26 1989-10-31 Kligman Albert M Methods for treatment of sundamaged human skin with retinoids
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100355892B1 (ko) * 2000-01-06 2002-10-12 주식회사 코리아나화장품 레티놀과 테트라디부틸 펜타에리스리틸히드록시히드로신나메이트를 함유하는 화장료 조성물

Also Published As

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ES2120417T3 (es) 1998-11-01
CA2090104A1 (en) 1992-12-28
NO930660D0 (no) 1993-02-24
NZ239051A (en) 1996-02-27
SG66224A1 (en) 1999-07-20
EP0549592B1 (en) 1998-08-19
EP0549592B2 (en) 2008-10-22
TW203009B (cg-RX-API-DMAC7.html) 1993-04-01
JPH06500079A (ja) 1994-01-06
FI981664A0 (fi) 1998-07-27
ES2120417T5 (es) 2009-04-01
PT98512B (pt) 1999-01-29
EP0549592A4 (cg-RX-API-DMAC7.html) 1995-03-29
FI930887L (fi) 1993-02-26
FI104407B (fi) 2000-01-31
NO930660L (no) 1993-04-15
JP2003238389A (ja) 2003-08-27
PH31832A (cg-RX-API-DMAC7.html) 1999-03-02
EG19852A (en) 1996-03-31
AU664973B2 (en) 1995-12-14
WO1993000085A1 (en) 1993-01-07
ZA915285B (en) 1993-03-31
DE69130020T2 (de) 1999-03-04
FI930887A7 (fi) 1993-02-26
NO304405B1 (no) 1998-12-14
MY132824A (en) 2007-10-31
CA2090104C (en) 2002-05-28
AU8299791A (en) 1993-01-25
JP3435510B2 (ja) 2003-08-11
DE69130020D1 (de) 1998-09-24
PT98512A (pt) 1992-06-30
MX9100278A (es) 1993-01-01
FI981664L (fi) 1998-07-27
BR9106891A (pt) 1994-06-14
JP3927511B2 (ja) 2007-06-13
EP0549592A1 (en) 1993-07-07
MA22240A1 (fr) 1992-04-01
MY131215A (en) 2007-07-31
CO4130180A1 (es) 1995-02-13
FI930887A0 (fi) 1993-02-26
NZ272557A (en) 1996-02-27
MX187577B (es) 1998-01-07

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