KR100191191B1 - 인터루킨-8합성억제의 카르보스티릴 유도체 - Google Patents

인터루킨-8합성억제의 카르보스티릴 유도체 Download PDF

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Publication number
KR100191191B1
KR100191191B1 KR1019950702533A KR19950702533A KR100191191B1 KR 100191191 B1 KR100191191 B1 KR 100191191B1 KR 1019950702533 A KR1019950702533 A KR 1019950702533A KR 19950702533 A KR19950702533 A KR 19950702533A KR 100191191 B1 KR100191191 B1 KR 100191191B1
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KR
South Korea
Prior art keywords
salt
derivative represented
chlorobenzoylamino
quinolone
carbostyryl derivative
Prior art date
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Expired - Fee Related
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KR1019950702533A
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English (en)
Korean (ko)
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KR950703957A (ko
Inventor
다까히데 마쓰다
시게루 오와다
히로시 무따
미끼 아이하라
히사오 다끼자와
겐이찌 이마가와
미끼오 기꾸찌
Original Assignee
오쓰까 아끼히꼬
오쓰까 세이야꾸 가부시키가이샤
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Application filed by 오쓰까 아끼히꼬, 오쓰까 세이야꾸 가부시키가이샤 filed Critical 오쓰까 아끼히꼬
Publication of KR950703957A publication Critical patent/KR950703957A/ko
Application granted granted Critical
Publication of KR100191191B1 publication Critical patent/KR100191191B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
KR1019950702533A 1993-10-21 1994-10-17 인터루킨-8합성억제의 카르보스티릴 유도체 Expired - Fee Related KR100191191B1 (ko)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP93-263417 1993-10-21
JP93-263419 1993-10-21
JP26341893 1993-10-21
JP26341993 1993-10-21
JP93-263418 1993-10-21
JP26341793 1993-10-21
JP94-89641 1994-04-27
JP93-89641 1994-04-27
JP8964194 1994-04-27
PCT/JP1994/001739 WO1995011026A1 (en) 1993-10-21 1994-10-17 Carbostyril derivative for inhibiting production of interleukin-8

Publications (2)

Publication Number Publication Date
KR950703957A KR950703957A (ko) 1995-11-17
KR100191191B1 true KR100191191B1 (ko) 1999-06-15

Family

ID=27467652

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950702533A Expired - Fee Related KR100191191B1 (ko) 1993-10-21 1994-10-17 인터루킨-8합성억제의 카르보스티릴 유도체

Country Status (14)

Country Link
US (1) US5637597A (https=)
EP (1) EP0674515B1 (https=)
JP (1) JP2839847B2 (https=)
KR (1) KR100191191B1 (https=)
CN (1) CN1073418C (https=)
AT (1) ATE184793T1 (https=)
AU (1) AU683697B2 (https=)
CA (1) CA2150546C (https=)
DE (1) DE69420832T2 (https=)
DK (1) DK0674515T3 (https=)
ES (1) ES2138092T3 (https=)
GR (1) GR3032091T3 (https=)
TW (1) TW296983B (https=)
WO (1) WO1995011026A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR004214A1 (es) * 1995-10-12 1998-11-04 Otsuka Pharma Co Ltd Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas
DE10029404B4 (de) * 2000-06-15 2009-10-29 Jagotec Ag Arzneiformulierung enthaltend Ciclosporin und deren Verwendung
FR2812548B1 (fr) * 2000-08-01 2002-09-20 Sanofi Synthelabo Utilisation de derives de quinolein-2(1h)-one ou un de leurs sels pharmaceutiquement acceptable pour la preparation d'un medicament destine au traitement de l'insuffisance renale
WO2004091724A1 (en) * 2002-10-08 2004-10-28 Wyeth Anthranilic acid derivatives useful in treating infection with hepatitis c virus
CN1859948B (zh) * 2003-07-30 2010-05-26 大塚制药株式会社 促进唾液分泌的喹诺酮衍生物
TWI340650B (en) * 2004-01-21 2011-04-21 Otsuka Pharma Co Ltd Amine saly of carbostyril derivative
MY149159A (en) 2005-11-15 2013-07-31 Hoffmann La Roche Method for treating joint damage
KR101551506B1 (ko) * 2007-08-10 2015-09-08 오츠카 세이야쿠 가부시키가이샤 레바미피드를 함유하는 의약 조성물
KR101104634B1 (ko) * 2009-08-25 2012-01-12 한림제약(주) 레바미피드를 포함하는 류마티스 관절염 예방 또는 치료용 약학 조성물
KR101182114B1 (ko) * 2010-03-05 2012-09-12 한림제약(주) 유효성분으로서 레바미피드를 함유하는 골관절염 예방 또는 치료용 약학 조성물
US9248196B2 (en) 2011-02-25 2016-02-02 Nuformix Limited Rebamipide complexes and cocrystals
US20140010882A1 (en) 2011-03-24 2014-01-09 Takakuni Matsuda Pharmaceutical composition for treating a disease in the oral cavity comprising rebamipide
JP6294773B2 (ja) * 2014-06-27 2018-03-14 株式会社ナールスコーポレーション 口腔粘膜疾患の予防または治療用経口製剤
WO2022128054A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammatory conditions of human skin (iv)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578381A (en) * 1982-07-05 1986-03-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
GB8334494D0 (en) * 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
JPS63119467A (ja) * 1987-10-21 1988-05-24 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
JPH02178227A (ja) * 1988-12-28 1990-07-11 Otsuka Pharmaceut Co Ltd 腎炎治療剤
JP2812998B2 (ja) * 1989-08-14 1998-10-22 大塚製薬 株式会社 胃炎治療剤
DK0543018T3 (da) * 1991-06-07 1996-02-05 Otsuka Pharma Co Ltd Antidiabetikum
CA2090876A1 (en) * 1991-07-03 1993-01-04 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulating composition
TW227558B (https=) * 1992-05-14 1994-08-01 Otsuka Pharma Co Ltd
JP2872546B2 (ja) * 1992-11-26 1999-03-17 大塚製薬株式会社 腸粘膜障害保護剤
AU5715994A (en) * 1992-12-24 1994-07-19 Otsuka Pharmaceutical Co., Ltd. Psoriasis remedy
EP0638311A4 (en) * 1993-03-02 1997-05-02 Otsuka Pharma Co Ltd REJECTION INHIBITOR FOR TRANSPLANTATIONS AND INTERLEUKIN PRODUCTION INHIBITOR 1.

Also Published As

Publication number Publication date
DE69420832D1 (de) 1999-10-28
KR950703957A (ko) 1995-11-17
EP0674515B1 (en) 1999-09-22
TW296983B (https=) 1997-02-01
CA2150546C (en) 2004-11-09
DE69420832T2 (de) 2000-01-13
ES2138092T3 (es) 2000-01-01
US5637597A (en) 1997-06-10
JP2839847B2 (ja) 1998-12-16
ATE184793T1 (de) 1999-10-15
CA2150546A1 (en) 1995-04-27
DK0674515T3 (da) 1999-12-20
CN1117268A (zh) 1996-02-21
JPH0812578A (ja) 1996-01-16
AU683697B2 (en) 1997-11-20
WO1995011026A1 (en) 1995-04-27
AU7864194A (en) 1995-05-08
EP0674515A1 (en) 1995-10-04
CN1073418C (zh) 2001-10-24
GR3032091T3 (en) 2000-03-31

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