JPWO2020218951A5 - - Google Patents
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- JPWO2020218951A5 JPWO2020218951A5 JP2021563239A JP2021563239A JPWO2020218951A5 JP WO2020218951 A5 JPWO2020218951 A5 JP WO2020218951A5 JP 2021563239 A JP2021563239 A JP 2021563239A JP 2021563239 A JP2021563239 A JP 2021563239A JP WO2020218951 A5 JPWO2020218951 A5 JP WO2020218951A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antigen
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2019112296 | 2019-04-23 | ||
| RU2019112296A RU2734432C1 (ru) | 2019-04-23 | 2019-04-23 | Моноклональное антитело, которое специфически связывается с GITR |
| PCT/RU2020/050080 WO2020218951A2 (ru) | 2019-04-23 | 2020-04-23 | Моноклональное антитело, которое специфически связывается с gitr |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022532991A JP2022532991A (ja) | 2022-07-21 |
| JPWO2020218951A5 true JPWO2020218951A5 (enExample) | 2023-05-02 |
| JP7695200B2 JP7695200B2 (ja) | 2025-06-18 |
Family
ID=69821666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021563239A Active JP7695200B2 (ja) | 2019-04-23 | 2020-04-23 | Ｇｉｔｒに特異的に結合するモノクローナル抗体 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US12410257B2 (enExample) |
| EP (1) | EP3964525A4 (enExample) |
| JP (1) | JP7695200B2 (enExample) |
| KR (1) | KR20220010501A (enExample) |
| CN (1) | CN110903392B (enExample) |
| AR (1) | AR118763A1 (enExample) |
| AU (1) | AU2020261207A1 (enExample) |
| BR (1) | BR112021021281A2 (enExample) |
| CA (1) | CA3137822A1 (enExample) |
| CL (1) | CL2021002792A1 (enExample) |
| CO (1) | CO2021014153A2 (enExample) |
| EA (1) | EA202192907A1 (enExample) |
| IL (1) | IL287531A (enExample) |
| JO (1) | JOP20210286A1 (enExample) |
| MA (2) | MA54969B2 (enExample) |
| MX (1) | MX2021012962A (enExample) |
| MY (1) | MY210018A (enExample) |
| PE (1) | PE20220144A1 (enExample) |
| PY (1) | PY2018606A (enExample) |
| RU (1) | RU2734432C1 (enExample) |
| TW (1) | TWI803718B (enExample) |
| UY (1) | UY38672A (enExample) |
| WO (1) | WO2020218951A2 (enExample) |
| ZA (1) | ZA202109374B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2724470C1 (ru) * | 2019-11-11 | 2020-06-23 | Автономная некоммерческая образовательная организация высшего образования Сколковский институт науки и технологий | Применение cas9 белка из бактерии pasteurella pneumotropica для модификации геномной днк в клетках |
| CN111732658B (zh) * | 2020-06-28 | 2022-04-26 | 英诺湖医药(杭州)有限公司 | 一组gitr单克隆抗体及其医药用途 |
| CN112362876B (zh) * | 2020-08-06 | 2023-12-15 | 武汉天德生物科技有限公司 | 一种检测早期老年痴呆症的胶体金试纸条及其制备方法 |
| CN112540179B (zh) * | 2020-08-06 | 2023-07-07 | 武汉天德生物科技有限公司 | 一种测试ApoE4蛋白含量的ELISA试剂盒 |
| CN111763257B (zh) * | 2020-09-01 | 2020-12-15 | 北京百奥赛图基因生物技术有限公司 | 抗gitr抗体及其用途 |
| CN114920845A (zh) * | 2020-12-31 | 2022-08-19 | 中元汇吉生物技术股份有限公司 | 特异性结合人IgG4的蛋白及其应用 |
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| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4740461A (en) | 1983-12-27 | 1988-04-26 | Genetics Institute, Inc. | Vectors and methods for transformation of eucaryotic cells |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| DE3668186D1 (de) | 1985-04-01 | 1990-02-15 | Celltech Ltd | Transformierte myeloma-zell-linie und dieselbe verwendendes verfahren zur expression eines gens, das ein eukaryontisches polypeptid kodiert. |
| US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4959455A (en) | 1986-07-14 | 1990-09-25 | Genetics Institute, Inc. | Primate hematopoietic growth factors IL-3 and pharmaceutical compositions |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US4912040A (en) | 1986-11-14 | 1990-03-27 | Genetics Institute, Inc. | Eucaryotic expression system |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| GB8809129D0 (en) | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5571894A (en) | 1991-02-05 | 1996-11-05 | Ciba-Geigy Corporation | Recombinant antibodies specific for a growth factor receptor |
| EP0940468A1 (en) | 1991-06-14 | 1999-09-08 | Genentech, Inc. | Humanized antibody variable domain |
| FI941572L (fi) | 1991-10-07 | 1994-05-27 | Oncologix Inc | Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä |
| DE69333807T2 (de) | 1992-02-06 | 2006-02-02 | Chiron Corp., Emeryville | Marker für krebs und biosynthetisches bindeprotein dafür |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| DE19544393A1 (de) | 1995-11-15 | 1997-05-22 | Hoechst Schering Agrevo Gmbh | Synergistische herbizide Mischungen |
| US6517529B1 (en) | 1999-11-24 | 2003-02-11 | Radius International Limited Partnership | Hemodialysis catheter |
| RU2369636C2 (ru) * | 2003-05-23 | 2009-10-10 | Уайт | Лиганд gitr и связанные с лигандом gitr молекулы и антитела и варианты их применения |
| CA2545603A1 (en) | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | Neonatal fc receptor (fcrn)-binding polypeptide variants, dimeric fc binding proteins and methods related thereto |
| US20100104564A1 (en) | 2005-03-29 | 2010-04-29 | Genevieve Hansen | Altered Antibody Fc Regions and Uses Thereof |
| EP1899477A4 (en) | 2005-07-01 | 2010-01-20 | Medimmune Inc | INTEGRATED APPROACH FOR GENERATING MULTIDOMAIN PROTEIN THERAPEUTIC APPLICATIONS |
| RU2595409C2 (ru) * | 2009-09-03 | 2016-08-27 | Мерк Шарп И Доум Корп., | Анти-gitr-антитела |
| TW201605896A (zh) | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
| AU2015266958A1 (en) * | 2014-05-28 | 2016-12-08 | Agenus Inc. | Anti-GITR antibodies and methods of use thereof |
| JP6449338B2 (ja) | 2014-06-06 | 2019-01-09 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | グルココルチコイド誘導腫瘍壊死因子受容体（ｇｉｔｒ）に対する抗体およびその使用 |
| CA2973978A1 (en) * | 2015-01-14 | 2016-07-21 | The Brigham And Women's Hospital, Inc. | Treatment of cancer with anti-lap monoclonal antibodies |
| US11059899B1 (en) | 2015-10-22 | 2021-07-13 | Ablynx N.V. | Polypeptides that bind glucocorticoid-induced TNFR family-related receptor (GITR) |
| AU2016364895A1 (en) | 2015-12-02 | 2018-06-07 | Agenus Inc. | Anti-GITR antibodies and methods of use thereof |
| KR102495601B1 (ko) | 2016-06-10 | 2023-02-06 | 리제너론 파마슈티칼스 인코포레이티드 | 항-gitr 항체 및 그것의 사용 |
| CN109641967A (zh) * | 2016-07-01 | 2019-04-16 | 戊瑞治疗有限公司 | 用GITR激动剂和CpG的组合的抗肿瘤疗法 |
| CN109843916B (zh) * | 2016-08-12 | 2023-10-31 | 詹森生物科技公司 | 具有增强的激动活性的Fc工程化抗TNFR超家族成员抗体及其使用方法 |
| CA3042727A1 (en) * | 2016-11-19 | 2018-05-24 | Potenza Therapeutics, Inc. | Anti-gitr antigen-binding proteins and methods of use thereof |
| JP7231549B2 (ja) * | 2017-02-06 | 2023-03-01 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | 抗体媒介性受容体シグナル伝達を増強するための組成物及び方法 |
| PE20191487A1 (es) * | 2017-03-03 | 2019-10-18 | Rinat Neuroscience Corp | Anticuerpos anti-gitr y metodos de uso de los mismos |
| TWI788340B (zh) * | 2017-04-07 | 2023-01-01 | 美商必治妥美雅史谷比公司 | 抗icos促效劑抗體及其用途 |
-
2019
- 2019-04-23 RU RU2019112296A patent/RU2734432C1/ru active
- 2019-12-03 CN CN201911222245.8A patent/CN110903392B/zh active Active
- 2019-12-03 TW TW108144110A patent/TWI803718B/zh active
-
2020
- 2020-04-22 UY UY0001038672A patent/UY38672A/es unknown
- 2020-04-23 JP JP2021563239A patent/JP7695200B2/ja active Active
- 2020-04-23 CA CA3137822A patent/CA3137822A1/en active Pending
- 2020-04-23 JO JOP/2021/0286A patent/JOP20210286A1/ar unknown
- 2020-04-23 MX MX2021012962A patent/MX2021012962A/es unknown
- 2020-04-23 WO PCT/RU2020/050080 patent/WO2020218951A2/ru not_active Ceased
- 2020-04-23 EP EP20794288.9A patent/EP3964525A4/en active Pending
- 2020-04-23 PE PE2021001765A patent/PE20220144A1/es unknown
- 2020-04-23 AR ARP200101146A patent/AR118763A1/es unknown
- 2020-04-23 EA EA202192907A patent/EA202192907A1/ru unknown
- 2020-04-23 US US17/605,933 patent/US12410257B2/en active Active
- 2020-04-23 BR BR112021021281A patent/BR112021021281A2/pt unknown
- 2020-04-23 AU AU2020261207A patent/AU2020261207A1/en active Pending
- 2020-04-23 MA MA54969A patent/MA54969B2/fr unknown
- 2020-04-23 KR KR1020217038209A patent/KR20220010501A/ko active Pending
- 2020-04-23 MY MYPI2021006363A patent/MY210018A/en unknown
- 2020-05-06 PY PY202002018606A patent/PY2018606A/es unknown
- 2020-06-30 MA MA55390A patent/MA55390B1/fr unknown
-
2021
- 2021-10-22 CO CONC2021/0014153A patent/CO2021014153A2/es unknown
- 2021-10-22 CL CL2021002792A patent/CL2021002792A1/es unknown
- 2021-10-24 IL IL287531A patent/IL287531A/en unknown
- 2021-11-22 ZA ZA2021/09374A patent/ZA202109374B/en unknown
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