JPWO2019150305A5 - - Google Patents
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- JPWO2019150305A5 JPWO2019150305A5 JP2020542110A JP2020542110A JPWO2019150305A5 JP WO2019150305 A5 JPWO2019150305 A5 JP WO2019150305A5 JP 2020542110 A JP2020542110 A JP 2020542110A JP 2020542110 A JP2020542110 A JP 2020542110A JP WO2019150305 A5 JPWO2019150305 A5 JP WO2019150305A5
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- Prior art keywords
- cancer
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- pharmaceutical composition
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 206010028980 Neoplasm Diseases 0.000 claims 12
- 201000011510 cancer Diseases 0.000 claims 9
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 210000003169 central nervous system Anatomy 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 102100030708 GTPase KRas Human genes 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 2
- 208000006593 Urologic Neoplasms Diseases 0.000 claims 2
- 208000002495 Uterine Neoplasms Diseases 0.000 claims 2
- 230000002159 abnormal effect Effects 0.000 claims 2
- 230000004663 cell proliferation Effects 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 2
- 201000002528 pancreatic cancer Diseases 0.000 claims 2
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 2
- 102200006538 rs121913530 Human genes 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 206010046766 uterine cancer Diseases 0.000 claims 2
- 206010000830 Acute leukaemia Diseases 0.000 claims 1
- 206010061424 Anal cancer Diseases 0.000 claims 1
- 208000007860 Anus Neoplasms Diseases 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010005949 Bone cancer Diseases 0.000 claims 1
- 208000018084 Bone neoplasm Diseases 0.000 claims 1
- 206010006143 Brain stem glioma Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 208000001976 Endocrine Gland Neoplasms Diseases 0.000 claims 1
- 206010014733 Endometrial cancer Diseases 0.000 claims 1
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 208000017604 Hodgkin disease Diseases 0.000 claims 1
- 208000010747 Hodgkins lymphoma Diseases 0.000 claims 1
- 208000005016 Intestinal Neoplasms Diseases 0.000 claims 1
- 206010061252 Intraocular melanoma Diseases 0.000 claims 1
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 1
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims 1
- 206010052178 Lymphocytic lymphoma Diseases 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 208000000821 Parathyroid Neoplasms Diseases 0.000 claims 1
- 208000002471 Penile Neoplasms Diseases 0.000 claims 1
- 206010034299 Penile cancer Diseases 0.000 claims 1
- 208000007913 Pituitary Neoplasms Diseases 0.000 claims 1
- 201000005746 Pituitary adenoma Diseases 0.000 claims 1
- 206010061538 Pituitary tumour benign Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000015634 Rectal Neoplasms Diseases 0.000 claims 1
- 206010038389 Renal cancer Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 206010039491 Sarcoma Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000021712 Soft tissue sarcoma Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 201000005969 Uveal melanoma Diseases 0.000 claims 1
- 201000005188 adrenal gland cancer Diseases 0.000 claims 1
- 208000024447 adrenal gland neoplasm Diseases 0.000 claims 1
- 201000011165 anus cancer Diseases 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 208000024207 chronic leukemia Diseases 0.000 claims 1
- 208000030381 cutaneous melanoma Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 201000002313 intestinal cancer Diseases 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 201000010982 kidney cancer Diseases 0.000 claims 1
- 208000029559 malignant endocrine neoplasm Diseases 0.000 claims 1
- 208000026045 malignant tumor of parathyroid gland Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 201000002575 ocular melanoma Diseases 0.000 claims 1
- 208000021310 pituitary gland adenoma Diseases 0.000 claims 1
- 206010038038 rectal cancer Diseases 0.000 claims 1
- 201000001275 rectum cancer Diseases 0.000 claims 1
- 208000015347 renal cell adenocarcinoma Diseases 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 201000003708 skin melanoma Diseases 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 201000002510 thyroid cancer Diseases 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
- 206010046885 vaginal cancer Diseases 0.000 claims 1
- 208000013139 vaginal neoplasm Diseases 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862624829P | 2018-02-01 | 2018-02-01 | |
| US62/624,829 | 2018-02-01 | ||
| US201862685383P | 2018-06-15 | 2018-06-15 | |
| US62/685,383 | 2018-06-15 | ||
| US201962795062P | 2019-01-22 | 2019-01-22 | |
| US62/795,062 | 2019-01-22 | ||
| PCT/IB2019/050795 WO2019150305A1 (en) | 2018-02-01 | 2019-01-31 | Substituted quinazoline and pyridopyrimidine derivatives useful as anticancer agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021512131A JP2021512131A (ja) | 2021-05-13 |
| JPWO2019150305A5 true JPWO2019150305A5 (enExample) | 2022-02-08 |
| JP7317028B2 JP7317028B2 (ja) | 2023-07-28 |
Family
ID=65685851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542110A Active JP7317028B2 (ja) | 2018-02-01 | 2019-01-31 | 抗ガン剤として有用な置換キナゾリン誘導体と置換ピリドピリミジン誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10662204B2 (enExample) |
| EP (1) | EP3746435B1 (enExample) |
| JP (1) | JP7317028B2 (enExample) |
| CA (1) | CA3089936C (enExample) |
| ES (1) | ES2926373T3 (enExample) |
| PY (1) | PY1906086A (enExample) |
| TW (1) | TW201942115A (enExample) |
| UY (1) | UY38070A (enExample) |
| WO (1) | WO2019150305A1 (enExample) |
Families Citing this family (90)
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| SG11201810171SA (en) | 2016-05-18 | 2018-12-28 | Mirati Therapeutics Inc | Kras g12c inhibitors |
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| RS66280B1 (sr) | 2018-11-09 | 2025-01-31 | Hoffmann La Roche | Jedinjenja sa kondenzovanim prstenovima |
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| CN114222743A (zh) * | 2019-08-16 | 2022-03-22 | 劲方医药科技(上海)有限公司 | 氧代六元环并嘧啶类化合物，其制法与医药上的用途 |
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-
2019
- 2019-01-29 TW TW108103302A patent/TW201942115A/zh unknown
- 2019-01-31 UY UY38070A patent/UY38070A/es not_active Application Discontinuation
- 2019-01-31 EP EP19709113.5A patent/EP3746435B1/en active Active
- 2019-01-31 PY PY201901906086A patent/PY1906086A/es unknown
- 2019-01-31 ES ES19709113T patent/ES2926373T3/es active Active
- 2019-01-31 WO PCT/IB2019/050795 patent/WO2019150305A1/en not_active Ceased
- 2019-01-31 JP JP2020542110A patent/JP7317028B2/ja active Active
- 2019-01-31 CA CA3089936A patent/CA3089936C/en active Active
- 2019-01-31 US US16/263,185 patent/US10662204B2/en active Active
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