JP2020105190A5 - - Google Patents

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Publication number
JP2020105190A5
JP2020105190A5 JP2020035656A JP2020035656A JP2020105190A5 JP 2020105190 A5 JP2020105190 A5 JP 2020105190A5 JP 2020035656 A JP2020035656 A JP 2020035656A JP 2020035656 A JP2020035656 A JP 2020035656A JP 2020105190 A5 JP2020105190 A5 JP 2020105190A5
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Japan
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cancer
pharmaceutical composition
disease
combination
pharmaceutically acceptable
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JP2020035656A
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English (en)
Japanese (ja)
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JP2020105190A (ja
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Publication of JP2020105190A publication Critical patent/JP2020105190A/ja
Publication of JP2020105190A5 publication Critical patent/JP2020105190A5/ja
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JP2020035656A 2012-10-16 2020-03-03 Pkm2調節因子およびそれらの使用方法 Withdrawn JP2020105190A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261714659P 2012-10-16 2012-10-16
US61/714,659 2012-10-16
US201361875855P 2013-09-10 2013-09-10
US61/875,855 2013-09-10

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2018186629A Division JP2019023209A (ja) 2012-10-16 2018-10-01 Pkm2調節因子およびそれらの使用方法

Publications (2)

Publication Number Publication Date
JP2020105190A JP2020105190A (ja) 2020-07-09
JP2020105190A5 true JP2020105190A5 (enExample) 2020-08-20

Family

ID=50488890

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2015537799A Active JP6243918B2 (ja) 2012-10-16 2013-10-16 Pkm2調節因子およびそれらの使用方法
JP2017203963A Expired - Fee Related JP6526767B2 (ja) 2012-10-16 2017-10-20 Pkm2調節因子およびそれらの使用方法
JP2018186629A Withdrawn JP2019023209A (ja) 2012-10-16 2018-10-01 Pkm2調節因子およびそれらの使用方法
JP2020035656A Withdrawn JP2020105190A (ja) 2012-10-16 2020-03-03 Pkm2調節因子およびそれらの使用方法
JP2020035657A Withdrawn JP2020097631A (ja) 2012-10-16 2020-03-03 Pkm2調節因子およびそれらの使用方法
JP2021120679A Active JP7128331B2 (ja) 2012-10-16 2021-07-21 Pkm2調節因子およびそれらの使用方法
JP2021129580A Pending JP2021181467A (ja) 2012-10-16 2021-08-06 Pkm2調節因子およびそれらの使用方法

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2015537799A Active JP6243918B2 (ja) 2012-10-16 2013-10-16 Pkm2調節因子およびそれらの使用方法
JP2017203963A Expired - Fee Related JP6526767B2 (ja) 2012-10-16 2017-10-20 Pkm2調節因子およびそれらの使用方法
JP2018186629A Withdrawn JP2019023209A (ja) 2012-10-16 2018-10-01 Pkm2調節因子およびそれらの使用方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2020035657A Withdrawn JP2020097631A (ja) 2012-10-16 2020-03-03 Pkm2調節因子およびそれらの使用方法
JP2021120679A Active JP7128331B2 (ja) 2012-10-16 2021-07-21 Pkm2調節因子およびそれらの使用方法
JP2021129580A Pending JP2021181467A (ja) 2012-10-16 2021-08-06 Pkm2調節因子およびそれらの使用方法

Country Status (6)

Country Link
US (5) US9394257B2 (enExample)
EP (1) EP2909181B1 (enExample)
JP (7) JP6243918B2 (enExample)
DK (1) DK2909181T3 (enExample)
ES (1) ES2644758T3 (enExample)
WO (1) WO2014062838A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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EP2909181B1 (en) * 2012-10-16 2017-08-09 Tolero Pharmaceuticals, Inc. Pkm2 modulators and methods for their use
LT3483164T (lt) 2017-03-20 2020-05-11 Forma Therapeutics, Inc. Pirolpirolo kompozicijos kaip piruvato kinazės (pkr) aktyvatoriai
US20200237766A1 (en) * 2017-10-13 2020-07-30 Tolero Pharmaceuticals, Inc. Pkm2 activators in combination with reactive oxygen species for treatment of cancer
EP3852791B1 (en) 2018-09-19 2024-07-03 Novo Nordisk Health Care AG Activating pyruvate kinase r
EP3853206B1 (en) 2018-09-19 2024-04-10 Novo Nordisk Health Care AG Treating sickle cell disease with a pyruvate kinase r activating compound
JP2022527451A (ja) * 2019-03-22 2022-06-02 スミトモ ダイニッポン ファーマ オンコロジー, インコーポレイテッド Pkm2モジュレーターおよびその使用方法
KR20210141621A (ko) * 2019-03-22 2021-11-23 스미토모 다이니폰 파마 온콜로지, 인크. Pkm2 조정제를 포함하는 조성물 및 그를 사용한 치료 방법
CN114206839B (zh) 2019-08-06 2025-03-07 拜奥克里斯特制药公司 血浆激肽释放酶抑制剂的生产规模合成
HRP20251148T1 (hr) 2019-09-19 2025-11-21 Novo Nordisk Health Care Ag Pripravci koji aktiviraju piruvat-kinazu r (pkr)
US12128035B2 (en) 2021-03-19 2024-10-29 Novo Nordisk Health Care Ag Activating pyruvate kinase R

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