JPWO2013118921A1 - ゲル化剤 - Google Patents
ゲル化剤 Download PDFInfo
- Publication number
- JPWO2013118921A1 JPWO2013118921A1 JP2013557621A JP2013557621A JPWO2013118921A1 JP WO2013118921 A1 JPWO2013118921 A1 JP WO2013118921A1 JP 2013557621 A JP2013557621 A JP 2013557621A JP 2013557621 A JP2013557621 A JP 2013557621A JP WO2013118921 A1 JPWO2013118921 A1 JP WO2013118921A1
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- Prior art keywords
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- gel
- Prior art date
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- 239000003349 gelling agent Substances 0.000 title claims abstract description 23
- 239000000203 mixture Substances 0.000 claims abstract description 67
- 150000001413 amino acids Chemical class 0.000 claims abstract description 22
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- 239000000539 dimer Substances 0.000 claims description 42
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- 150000002009 diols Chemical class 0.000 claims description 33
- 150000002148 esters Chemical class 0.000 claims description 31
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- 229930195729 fatty acid Natural products 0.000 claims description 28
- 235000001014 amino acid Nutrition 0.000 claims description 27
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- PKGIJUSIJXTQFL-QFIPXVFZSA-N (4s)-5-(dibutylamino)-4-(dodecanoylamino)-5-oxopentanoic acid Chemical compound CCCCCCCCCCCC(=O)N[C@@H](CCC(O)=O)C(=O)N(CCCC)CCCC PKGIJUSIJXTQFL-QFIPXVFZSA-N 0.000 claims description 10
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- 238000002834 transmittance Methods 0.000 description 5
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- 238000005160 1H NMR spectroscopy Methods 0.000 description 4
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- 239000004471 Glycine Substances 0.000 description 4
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- 239000005642 Oleic acid Substances 0.000 description 4
- 150000001298 alcohols Chemical class 0.000 description 4
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- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 4
- 239000002738 chelating agent Substances 0.000 description 4
- UKMSUNONTOPOIO-UHFFFAOYSA-N docosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(O)=O UKMSUNONTOPOIO-UHFFFAOYSA-N 0.000 description 4
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- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 3
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 3
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- 229960002703 undecylenic acid Drugs 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
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- ZNVKGUVDRSSWHV-UHFFFAOYSA-L zinc;4-hydroxybenzenesulfonate Chemical compound [Zn+2].OC1=CC=C(S([O-])(=O)=O)C=C1.OC1=CC=C(S([O-])(=O)=O)C=C1 ZNVKGUVDRSSWHV-UHFFFAOYSA-L 0.000 description 1
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- IPCAPQRVQMIMAN-UHFFFAOYSA-L zirconyl chloride Chemical compound Cl[Zr](Cl)=O IPCAPQRVQMIMAN-UHFFFAOYSA-L 0.000 description 1
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Classifications
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
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- A—HUMAN NECESSITIES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
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- A61Q1/02—Preparations containing skin colorants, e.g. pigments
- A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
Abstract
Description
即ち、本発明は、以下の態様を含む。
式(I):
(式中、R1及びR2はそれぞれ独立に炭素原子数1〜7の直鎖または分枝鎖のアルキル基を示し、R3は炭素原子数3〜15の直鎖または分枝鎖のアルキル基を示し、nは1または2を示す)で表わされ、
DL体比(D体/L体(重量/重量))が5/95〜20/80または80/20〜95/5であるN−アシル酸性アミノ酸ジアルキルアミドを含有するゲル化剤。
[2]の1
N−アシル酸性アミノ酸ジアルキルアミドが、N−2−エチルヘキサノイルグルタミン酸ジブチルアミドまたはN−ラウロイルグルタミン酸ジブチルアミドである[1]に記載のゲル化剤。
[2]の2
N−アシル酸性アミノ酸ジアルキルアミドが、N−2−エチルヘキサノイルグルタミン酸ジブチルアミドおよびN−ラウロイルグルタミン酸ジブチルアミドの混合物である[1]に記載のゲル化剤。
[3]
DL体比(D体/L体(重量/重量))が5/95〜20/80である上記[1]または[2]に記載のゲル化剤。
[4]
上記[1]から[3]のいずれか一項に記載のゲル化剤(成分A)及び油性基剤(成分B)を含有するゲル状組成物。
[5]
油性基剤(成分B)が、シリコーン油、エステル油、炭化水素、高級アルコール、多価アルコール、及び脂肪酸からなる群から選択される上記[4]に記載のゲル状組成物。
[6]
さらにアシルアミノ酸とダイマージオールとのエステル及び/またはアシルアミノ酸と脂肪酸とダイマージオールとのエステル(成分C)を含有する上記[4]または[5]に記載のゲル状組成物。
[7]
成分Cが、ラウロイルグルタミン酸とダイマージオールとのエステル、ラウロイルザルコシンとダイマージオールとのエステル、及びビス(ラウロイルグルタミン酸/ラウロイルザルコシン)ダイマージリノレイルからなる群から選択される1以上である[6]に記載のゲル状組成物。
[8]
成分Aの配合量が0.01〜30重量%であり、成分Cの配合量が0.1〜60重量%であり、成分Bと成分Cの配合量の合計が30〜99.99重量%であることを特徴とする上記[6]または[7]に記載のゲル状組成物。
[9]
形状が、棒状であることを特徴とする上記[4]〜[8]に記載のゲル状組成物。
[10]
制汗剤、リップスティックまたは口紅である上記[4]〜[9]に記載のゲル状組成物。
本発明においてゲル化剤とは、液体を増粘させ、またはゼリー状または固形状まで変化させる物質または組成物をいう。本発明においては特に、油性の液体(油性基材)に対するゲル化剤として有用である。
また、当該N−アシル酸性アミノ酸ジアルキルアミド(成分A)及び油性基剤(成分B)、さらにアシルアミノ酸とダイマージオールとのエステル及び/またはアシルアミノ酸と脂肪酸とダイマージオールとのエステル(成分C)を含有するゲル状組成物、特に棒状のゲル状組成物に関する。
本発明のN−アシル酸性アミノ酸ジアルキルアミド(成分A)は、式(I)で表される。
本発明のN−アシルアミノ酸ジアルキルアミド(成分A)は、油性基剤(成分B)に加熱溶解させ、室温に冷却することによりゲル状組成物を調製することができる。油性基剤(成分B)としては、具体的には、メチルポリシロキサン、高重合メチルポリシロキサン、ポリオキシエチレン・メチルポリシロキサン共重合体、ポリオキシプロピレン・メチルポリシロキサン共重合体、ポリ(オキシエチレン、オキシプロピレン)・メチルポリシロキサン共重合体、ステアロキシメチルポリシロキサン、ステアロキシトリメチルシラン、メチルハイドロジェンポリシロキサン、オクタメチルポリシロキサン、デカメチルポリシロキサン、デカメチルシクロペンタシロキサン、オクタメチルシクロテトラシロキサン、テトラヒドロテトラメチルシクロテトラシロキサン、メチルシクロポリシロキサン、シクロペンタシロキサン、ドデカメチルシクロヘキサシロキサン、メチルフェニルポリシロキサン、トリメチルシロキシケイ酸、アミノエチルアミノプロピルシロキサン・ジメチルシロキサン、シラノール変性ポリシロキサン、アルコキシ変性ポリシロキサン、脂肪酸変性ポリシロキサン、フッ素変性ポリシロキサン、エポキシ変性ポリシロキサン、アルコキシ変性ポリシロキサンパーフルオロポリエーテル、ポリ酢酸ビニルジメチルポリシロキサンなどのシリコーン油;ミリスチン酸ミリスチル、ラウリン酸ヘキシル、オレイン酸デシル、ミリスチン酸イソプロピル、ジメチルオクタン酸ヘキシルデシル、モノステアリン酸グリセリン、トリ−2−エチルヘキサン酸グリセリル、フタル酸ジエチル、モノステアリン酸エチレングリコール、オキシステアリン酸オクチル、安息香酸アルキルエステル等のエステル油;流動パラフィン、ポリイソブテン、ワセリン、スクワラン等の炭化水素;セチルアルコール、イソステアリルアルコール、ラウリルアルコール、ヘキサデシルアルコール、オクチルドデカノール等の高級アルコール;イソステアリン酸、ウンデシレン酸、オレイン酸等の脂肪酸;ラノリン、還元ラノリン、カルナバロウ等のロウ;ミンク油、カカオ油、ヤシ油、パーム核油、ツバキ油、ゴマ油、ヒマシ油、オリーブ油等の油脂;エチレン・α−オレフィン・コオリゴマー等が挙げられる。シリコーン油、エステル油、炭化水素、高級アルコール、及び脂肪酸が好ましく、シリコーン油、エステル油、炭化水素、及び高級アルコールが更に好ましい。
本発明のゲル状組成物にアシルアミノ酸とダイマージオールとのエステル及び/またはアシルアミノ酸と脂肪酸とダイマージオールとのエステル(成分C)を添加すると、更になじみ及びのびに優れ、べたつきのないゲル状組成物を得ることができる。
成分Cと合わせて使用する場合には、成分Bと成分Cの重量を合わせて、30重量%〜99.99重量%となるように調製する。成分Bと成分Cの合計重量は、ゲルネットワークが形成され保持されるという観点で、30重量%が好ましく、40重量%がより好ましく、50重量%が更に好ましく、60重量%が更に一層好ましく、70重量%が最も好ましい。ゲル状組成物全体に対する油性基剤の配合量の上限値(重量%)は、効率的にゲルが形成し得るという観点で、99.99%が好ましく、99.9%がより好ましく、99.5%が更に好ましい。
合成方法:L−グルタミン酸ナトリウム一水和物110gを水140g、25%水酸化ナトリウム水溶液84gに溶解させて、10℃に冷却した。アセトン110gを加えた後、2−エチルヘキサノイルクロライド87gと25%水酸化ナトリウム水溶液84gを滴下した。アシル化反応液を100gの水で希釈し、75%硫酸80gで中和し、油状分離させた。水層を除去し油層を減圧濃縮して油状物質を得た。この油状物質をメタノール742gに溶解し、75%硫酸7.9gを加え9時間還流させた。反応液を35℃まで放冷し、n−ブチルアミン8.8gで中和後メタノールを留去し、油状物質をえた。この油状物質をトルエン643gと、n−ブチルアミン271gを加えて、90℃で10時間加熱撹拌した。これに温水506g、75%硫酸165gを加えて、油状分離させ、水層を除去した。油層に温水1200gを加えて、常圧で溶媒を除去して白色固体のスラリー液を得た。この固体をろ過後、メタノールアセトン混合溶媒により再結晶し、ろ過後50℃で真空乾燥してN−2−エチルヘキサノイル−L−グルタミン酸ジブチルアミドを50g得た。
NMR:1H−NMRピーク(CDCl3) δ:0.85−0.95(m,12H)、1.25−1.62(m,16H)、1.98−2.10(m,3H)、2.26−2.33(m,1H)、2.42−2.50(m,1H)、3.22−3.29(m,4H)、4.30−4.36(m,1H)、5.97(br,1H)、6.91(br,1H)、7.12(br,1H)
融点:200℃
DL体比(D体/L体(重量/重量)):0/100
合成方法:DL−グルタミン酸63gを水130g、25%水酸化ナトリウム水溶液126gに溶解させて、10℃に冷却した。イソプロピルアルコール63gを加えた後、2−エチルヘキサノイルクロライド64gと25%水酸化ナトリウム水溶液74gを滴下した。アシル化反応液を75%硫酸56gで中和し、油状分離させた。水層を除去し油層を減圧濃縮して油状物質を得た。この油状物質をn−ブタノール221gに溶解し、98%硫酸7.7gを加え8時間還流させた。反応液を減圧濃縮して油状物質を得、この油状物質にn−ブチルアミン180gを加えて、90℃で8時間加熱撹拌した。反応液を減圧濃縮して油状物質を得、これに水300gを加え、75%硫酸にて中和し、油状分離させ、水層を除去した。油層を減圧濃縮して、白色固体のスラリー液を得、この固体をろ過後、50℃で真空乾燥してN−2−エチルヘキサノイル−DL−グルタミン酸ジブチルアミドを105g得た。
NMR:1H−NMRピーク(CDCl3) δ:0.85−0.95(m,12H)、1.25−1.62(m,16H)、1.98−2.10(m,3H)、2.26−2.33(m,1H)、2.42−2.50(m,1H)、3.22−3.29(m,4H)、4.30−4.36(m,1H)、5.97(br,1H)、6.91(br,1H)、7.12(br,1H)
融点:175℃
DL体比(D体/L体(重量/重量)):50/50
合成方法:L−グルタミン酸ナトリウム一水和物110gを水140g、25%水酸化ナトリウム水溶液84gに溶解させて、10℃に冷却した。アセトン110gを加えた後、ラウロイルクロライド116gと25%水酸化ナトリウム水溶液80gを滴下した。アシル化反応液を100gの水で希釈し、75%硫酸80gで中和し、油状分離させた。水層を除去し油層を減圧濃縮して油状物質を得た。この油状物質をメタノール742gに溶解し、75%硫酸7.9gを加え9時間還流させた。反応液を35℃まで放冷し、n−ブチルアミン8.8gで中和後メタノールを留去し、油状物質をえた。この油状物質をトルエン643gと、n−ブチルアミン271gを加えて、90℃で10時間加熱撹拌した。これに温水506g、75%硫酸165gを加えて、油状分離させ、水層を除去した。油層に温水1200gを加えて、常圧で溶媒を除去して白色固体のスラリー液を得た。この固体をろ過後、メタノールにより再結晶し、ろ過後50℃で真空乾燥してN−ラウロイル−L−グルタミン酸ジブチルアミドを58g得た。
NMR:1H−NMRピーク(CDCl3) δ:0.86−0.95(m,9H)、1.25−1.66(m,26H)、1.92−2.10(m,2H)、2.20−2.32(m,3H)、2.38−2.48(m,1H)、3.22−3.28(m,4H)、4.32−4.36(m,1H)、6.03(br,1H)、6.82(br,1H)、7.00(br,1H)
融点:166℃
DL体比(D体/L体(重量/重量)):0/100
合成方法:DL−グルタミン酸57gを水120g、25%水酸化ナトリウム水溶液108gに溶解させて、10℃に冷却した。イソプロピルアルコール57gを加えた後、ラウロイルクロライド79gと25%水酸化ナトリウム水溶液71gを滴下した。アシル化反応液を75%硫酸50gで中和すると、白色固体が析出し、この固体をろ過、水で洗浄した。この固体をn−ブタノール200gに溶解し、98%硫酸7.4gを加え8時間還流させた。反応液を減圧濃縮して油状物質を得、この油状物質にn−ブチルアミン164gを加えて、90℃で8時間加熱撹拌した。反応液を減圧濃縮して油状物質を得、これに水300gを加え、75%硫酸にて中和し、油状分離させ、水層を除去した。油層を減圧濃縮して、白色固体のスラリー液を得、この固体をろ過後、50℃で真空乾燥してN−ラウロイル−DL−グルタミン酸ジブチルアミドを98g得た。
NMR:1H−NMRピーク(CDCl3) δ:0.86−0.95(m,9H)、1.25−1.66(m,26H)、1.92−2.10(m,2H)、2.20−2.32(m,3H)、2.38−2.48(m,1H)、3.22−3.28(m,4H)、4.32−4.36(m,1H)、6.03(br,1H)、6.82(br,1H)、7.00(br,1H)
融点:142℃
DL体比(D体/L体(重量/重量)):50/50
カラム:CHIRALPAK AS(ダイセル社製)
カラム温度:40℃
検出:254nm(UV)
溶離液:ヘキサン/イソプロピルアルコール 96/4
流速:1.0 mL/min
[溶解温度]
4種の成分B(ミネラルオイル、ミリスチン酸イソプロピル、トリエチルヘキサノイン、シクロペンタシロキサン/オクチルドデカノール(80/20混合物))に、DL体比(D体/L体(重量/重量))が、50/50、30/70、10/90、0/100のN−2−エチルヘキサノイルグルタミン酸ジブチルアミドをそれぞれ1重量%となるように添加し、50mLサンプル管瓶にいれ90℃のオイルバスに保持し20分攪拌した。溶解しない場合オイルバスの温度を5℃上昇させ、同様の手順を繰り返し、各N−2−エチルヘキサノイルグルタミン酸ジブチルアミドが完全に溶解した温度を溶解温度(t)を測定した。DL比が0/100のN−2−エチルヘキサノイルグルタミン酸ジブチルアミドの溶解温度を(t0)とし以下の基準で評価した。
なお、DL比が30/70、10/90のN−2−エチルヘキサノイルグルタミン酸ジブチルアミドは合成例1及び合成例2のN−2−エチルヘキサノイルグルタミン酸ジブチルアミドを適宜混合して調製した。以下の実施例においても同じである。
◎:t−t0が25℃以上
○:t−t0が15℃以上25℃未満
△:t−t0が5℃以上15℃未満
×:t−t0が5未満
上記と同じ4種の成分Bに、上記と同じ各N−2−エチルヘキサノイルグルタミン酸ジブチルアミドを1重量%となるように添加し、オイルバスで加熱溶解し、24時間、室温25℃の部屋で放冷し、ゲル状組成物を得た。得られたゲル状組成物のゲル強度(G)をレオメータ(FUDOH RHEO METER NRM−2010−J−CW)にて測定し、DL比が0/100のN−2−エチルヘキサノイルグルタミン酸ジブチルアミドの溶解温度を(G0)とし以下の基準で評価した。
以下の基準で評価した。アダプターはプルーム用・粘弾性用、10φを用い、試料台速度は6cm/minとした。
◎:G/G0が1.0超
○:G/G0が0.5超、1.0以下
△:G/G0が0.3超、0.5以下
×:G/G0が0.3以下
上記で得られたゲル状組成物の透過率(T)を分光光度計(V−750:日本分光社製、波長520nm、光路長1cm)を用いて測定し、DL比が0/100のN−2−エチルヘキサノイルグルタミン酸ジブチルアミドの透過率を(T0)とし以下の基準で評価した。
◎:T/T0が1.0超
○:T/T0が0.6超、1.0以下
△:T/T0が0.4超、0.6以下
×:T/T0が0.4以下
上記で得られたゲル状組成物を皮膚に塗布した時ののび及びなじみについて、専門パネラー4人により、以下の基準で評価した。
・皮膚に対するのびのよさ(4点満点で評価)
4:のびが非常によい。
3:のびがよい
2:のびが悪い。
1:のびが非常に悪い。
・皮膚へのなじみやすさ(4点満点で評価)
4:皮膚へのなじみ感が非常によい。
3:皮膚へのなじみ感がよい。
2:皮膚へのなじみ感が悪い。
1:皮膚へのなじみ感が非常に悪い。
その評価結果の平均点が3.5以上を◎、2.5以上3.5未満を○、1.5以上2.5未満を△、1.5未満を×とした。評価結果を表1に併せて示す。
◎を3点、○を2点、△を1点、×を0点として、総合評価を計算した。
ミネラルオイル:村松石油社製、モレスコホワイトP−55
ミリスチン酸イソプロピル:高級アルコール工業社製、IPM−R
トリエチルヘキサノイン:高級アルコール工業社製、TOG
シクロペンタシロキサン:東レ・ダウコーニング社製、SH245
オクチルドデカノール:高級アルコール工業社製、リソノール20SP
N−2−エチルヘキサノイルグルタミン酸ジブチルアミドをN−ラウロイルグルタミン酸ジブチルアミドに変更した以外は上記と同様に、溶解温度、ゲル強度、透過率、なじみ、のびを測定し、評価した。(ただし、シクロペンタデカン/オクチルドデカノールの場合のみ2重量%のN−ラウロイルグルタミン酸ジブチルアミドを添加している。)
[のび・なじみ・べたつき]
下記表3に示す原料を140℃のオイルバスを用いて加熱溶解し、専用容器内で24時間、室温25℃の部屋で放冷することによりリップスティックを調製した。なお、比較例27のリップスティックについては140℃では調製できなかったため、150℃のオイルバスを使用した。
表3で得られたリップスティックを皮膚に塗布した際の、(1)のび、(2)なじみ、(3)べたつき、の3項目について、以下の評価基準に基づき専門パネラー4人により評価した。専門パネラー4人により、以下の基準で評価した。
・皮膚に対するのびのよさ(4点満点で評価)
4:のびが非常によい。
3:のびがよい
2:のびが悪い。
1:のびが非常に悪い。
・皮膚へのなじみやすさ(4点満点で評価)
4:皮膚へのなじみ感が非常によい。
3:皮膚へのなじみ感がよい。
2:皮膚へのなじみ感が悪い。
1:皮膚へのなじみ感が非常に悪い。
・べたつき(4点満点で評価)
4:べたつきがまったく感じられない。
3:べたつきがあまり感じられない。
2:べたつきが感じられる。
1:べたつきが非常に感じられる。
平均点が3.5以上を◎、2.5以上3.5未満を○、1.5以上2.5未満を△、1.5未満を×とした。
得られたリップスティックの折れ強度をレオメータ(FUDOH RHEOMETER NRM−2010−J−CW)にて測定した。アダプターは歯形押棒Aを用い、試料台速度は6cm/minとした。リップスティックの断面は直径10mmの円形である。専用容器より長さが20mmとなるようにリップスティックを伸ばし、その中間部(専用容器末端より10mmの部分)にアダプターが接触するように測定サンプルを固定した。この測定で得られる折れ強度について、以下の基準で評価した。
◎:200g/cm2以上
○:150g/cm2以上200g/cm2未満
△:100g/cm2以上150g/cm2未満
×:100g/cm2未満
ビス(ラウロイルグルタミン酸/ラウロイルサルコシン)ダイマージリノレイル:味の素社製、「エルデュウ」DA−209
オクチルドデカノール:高級アルコール工業社製、リソノール20SP
リンゴ酸ジイソステアリル:高級アルコール工業社製、ハイマレートDIS
シクロペンタシロキサン:東レ・ダウコーニング社、SH245 Fluid
ラウロイルグルタミン酸ジ(フィトステリル/オクチルドデシル):味の素社製、「エルデュウ」PS−203
ダイマージリノール酸ダイマージリノレイルビス(ベヘニル/イソステアリル/フィトステリル):日本精化社製、PLANDOOL G
水添ポリイソブテン:日油社製、パールリーム18
下記表4に示す原料を140℃のオイルバスで加熱溶解し、専用容器内で24時間、室温25℃の部屋で放冷することによりリップスティックを調製した。
得られたリップスティックは、実施例9とほぼ同等の性能を示した。
使用した成分は表3と同じである。
表5の1)〜5)を105℃で溶解した後、80℃まで冷却し上記6)を添加し、室温まで放冷し発汗抑制ゲルスティックを得た。本品は、十分なゲル強度を有し、のび、及びなじみに優れ、べたつきのないものであった。
Claims (10)
- N−アシル酸性アミノ酸ジアルキルアミドが、N−2−エチルヘキサノイルグルタミン酸ジブチルアミドまたはN−ラウロイルグルタミン酸ジブチルアミドである請求項1に記載のゲル化剤。
- DL体比(D体/L体(重量/重量))が5/95〜20/80である請求項1または2に記載のゲル化剤。
- 請求項1から3のいずれか一項に記載のゲル化剤(成分A)及び油性基剤(成分B)を含有するゲル状組成物。
- 油性基剤(成分B)が、シリコーン油、エステル油、炭化水素、高級アルコール、多価アルコール、及び脂肪酸からなる群から選択される請求項4に記載のゲル状組成物。
- さらにアシルアミノ酸とダイマージオールとのエステル及び/またはアシルアミノ酸と脂肪酸とダイマージオールとのエステル(成分C)を含有する請求項4または5に記載のゲル状組成物。
- 成分Cが、ラウロイルグルタミン酸とダイマージオールとのエステル、ラウロイルザルコシンとダイマージオールとのエステル、及びビス(ラウロイルグルタミン酸/ラウロイルザルコシン)ダイマージリノレイルからなる群から選択される1以上である請求項6に記載のゲル状組成物。
- 成分Aの配合量が0.01〜30重量%であり、成分Cの配合量が0.1〜60重量%であり、成分Bと成分Cの配合量の合計が30〜99.99重量%であることを特徴とする請求項6または7に記載のゲル状組成物。
- 形状が、棒状であることを特徴とする請求項4〜8に記載のゲル状組成物。
- 制汗剤、リップスティックまたは口紅である請求項4〜9に記載のゲル状組成物。
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JPS53121615A (en) * | 1977-03-31 | 1978-10-24 | Fuji Photo Film Co Ltd | Photographic material |
US6423324B1 (en) * | 2000-06-20 | 2002-07-23 | Cosmolab, Inc. | Temperature-stable polyamide resin-based composition, and products |
JP2002316971A (ja) * | 2001-02-13 | 2002-10-31 | Ajinomoto Co Inc | 油性基剤のゲル化剤 |
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